年別の研究成果
年別の研究成果
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Article
Concise synthesis of 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) as a protected form based on a new transformation of α,β-unsaturated ester to α-oxocarboxylic acid ester via diol cyclic sulfite
Kuboki, A., Tajimi, T., Tokuda, Y., Kato, D. I., Sugai, T. & Ohira, S., 2004 5月 31, In: Tetrahedron Letters. 45, 23, p. 4545-4548 4 p.研究成果: Article › 査読
17 被引用数 (Scopus) -
Conditional knockout of Mn superoxide dismutase in postnatal motor neurons reveals resistance to mitochondrial generated superoxide radicals
Misawa, H., Nakata, K., Matsuura, J., Moriwaki, Y., Kawashima, K., Shimizu, T., Shirasawa, T. & Takahashi, R., 2006 7月, In: Neurobiology of Disease. 23, 1, p. 169-177 9 p.研究成果: Article › 査読
42 被引用数 (Scopus) -
Conformational equilibrium shift underlies altered K+ channel gating as revealed by NMR
Iwahashi, Y., Toyama, Y., Imai, S., Itoh, H., Osawa, M., Inoue, M. & Shimada, I., 2020 12月 1, In: Nature communications. 11, 1, 5168.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Construction of 2,6,9,11-tetraoxatricyclo[6.2.1.03,8]undecane containing 4-keto-D-glucose skeleton
Fujitani, B., Hanaya, K., Higashibayashi, S., Shoji, M. & Sugai, T., 2017 12月 21, In: Tetrahedron. 73, 51, p. 7217-7222 6 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Control of the nitrile-hydrolyzing enzyme activity in Rhodococcus rhodochrous IFO 15564: Preferential action of nitrile hydratase and amidase depending on the reaction condition factors and its application to the one-pot preparation of amides from aldehydes
Kashiwagi, M., Fuhshuku, K. I. & Sugai, T., 2004 6月 21, In: Journal of Molecular Catalysis B: Enzymatic. 29, 1-6, p. 249-258 10 p.研究成果: Article › 査読
20 被引用数 (Scopus) -
Convergent synthesis of the HIJKLM ring fragment of ciguatoxin CTX3C
Uehara, H., Oishi, T., Inoue, M., Shoji, M., Nagumo, Y., Kosaka, M., Le Brazidec, J. Y. & Hirama, M., 2002 8月 5, In: Tetrahedron. 58, 32, p. 6493-6512 20 p.研究成果: Article › 査読
56 被引用数 (Scopus) -
Convergent synthesis of the IJKLM ring fragment of ciguatoxin CTX3C
Oishi, T., Nagumo, Y., Shoji, M., Le Brazidec, J. Y., Uehara, H. & Hirama, M., 1999 10月 21, In: Chemical Communications. 20, p. 2035-2036 2 p.研究成果: Article › 査読
48 被引用数 (Scopus) -
Copper(II)-catalyzed oxidation of d-α-tocopherol by oxygen in aqueous solution
Nagata, Y., Miyamoto, C., Matsushima, Y. & Matsumoto, S., 2000 1月, In: Chemical and Pharmaceutical Bulletin. 48, 1, p. 71-76 6 p.研究成果: Article › 査読
Open Access8 被引用数 (Scopus) -
Correlation of physicochemical property and the dissolution behavior of ingredients of an antihypertensive combination tablet
Nagata, Y., Anan, Y. & Kanazawa, H., 2015 12月 9, In: BUNSEKI KAGAKU. 64, 11, p. 835-844 10 p.研究成果: Article › 査読
Open Access -
Covalent change of major intrinsic polypeptide (MIP26K) of lens membrane during human senile cataractogenesis
Takemoto, L. & Takehana, M., 1986 3月 28, In: Biochemical and Biophysical Research Communications. 135, 3, p. 965-971 7 p.研究成果: Article › 査読
17 被引用数 (Scopus) -
Covalent changes in MIP26K during aging of the human lens membrane
Takemoto, L., Takehana, M. & Horwitz, J., 1986 1月 1, In: Investigative Ophthalmology and Visual Science. 27, 3, p. 443-446 4 p.研究成果: Article › 査読
35 被引用数 (Scopus) -
Creation of pure nanodrugs and their anticancer properties
Kasai, H., Murakami, T., Ikuta, Y., Koseki, Y., Baba, K., Oikawa, H., Nakanishi, H., Okada, M., Shoji, M., Ueda, M., Imahori, H. & Hashida, M., 2012 10月 8, In: Angewandte Chemie - International Edition. 51, 41, p. 10315-10318 4 p.研究成果: Article › 査読
114 被引用数 (Scopus) -
Critical roles of acetylcholine and the muscarinic and nicotinic acetylcholine receptors in the regulation of immune function
Kawashima, K., Fujii, T., Moriwaki, Y. & Misawa, H., 2012 11月 27, In: Life Sciences. 91, 21-22, p. 1027-1032 6 p.研究成果: Article › 査読
117 被引用数 (Scopus) -
Crosslinked Poly(N-Isopropylacrylamide)-Based Microfibers as Cell Manipulation Materials with Prompt Cell Detachment
Konishi, T., Mizutani Akimoto, A., Nishimoto, T., Tokura, Y., Tenjimbayashi, M., Homma, K., Matsukawa, K., Kaku, T., Hiruta, Y., Nagase, K., Kanazawa, H. & Shiratori, S., 2019 12月 1, In: Macromolecular Rapid Communications. 40, 23, 1900464.研究成果: Article › 査読
4 被引用数 (Scopus) -
Cysteine-derived organocatalyst in a highly enantioselective intramolecular Michael reaction
Hayashi, Y., Gotoh, H., Tamura, T., Yamaguchi, H., Masui, R. & Shoji, M., 2005 11月 23, In: Journal of the American Chemical Society. 127, 46, p. 16028-16029 2 p.研究成果: Article › 査読
198 被引用数 (Scopus) -
Dearomative Oxidative Rearrangement of [3]Cyclo-1,8-carbazolylene
Yasui, M., Ohtsu, H., Kawano, M., Hanaya, K., Sugai, T. & Higashibayashi, S., 2018, In: Chemistry Letters. 47, 11, p. 1357-1359 3 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Degradation of Derivatives of N-Acetyl-D-glucosamine by rhodococcus rhodochrous IFO 15564: Substrate specificity and its application to the synthesis of Allyl α-N-Acetyl-D-glucosaminide
Kuboki, A., Komiya, R., Sekiguchi, T., Katsuragi, K., Sugai, T. & Ohta, H., 1998, In: Bioscience, Biotechnology and Biochemistry. 62, 8, p. 1581-1585 5 p.研究成果: Article › 査読
4 被引用数 (Scopus) -
Design and synthesis of temperature-responsive polymer/silica hybrid nanoparticles and application to thermally controlled cellular uptake
Hiruta, Y., Nemoto, R. & Kanazawa, H., 2017 5月 1, In: Colloids and Surfaces B: Biointerfaces. 153, p. 2-9 8 p.研究成果: Article › 査読
11 被引用数 (Scopus) -
Design of Environmentally Responsive Fluorescent Polymer Probes for Cellular Imaging
Yamada, A., Hiruta, Y., Wang, J., Ayano, E. & Kanazawa, H., 2015 8月 10, In: Biomacromolecules. 16, 8, p. 2356-2362 7 p.研究成果: Article › 査読
40 被引用数 (Scopus) -
Design of functional thermoresponsive polymer brushes and their application to bioseparation
Nagase, K., Okano, T. & Kanazawa, H., 2018 3月, In: KOBUNSHI RONBUNSHU. 75, 2, p. 143-154 12 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Design of tetra-arm PEG-crosslinked thermoresponsive hydrogel for 3D cell culture
Akimoto, A. M., Hasuike, E., Tada, H., Nagase, K., Okano, T., Kanazawa, H. & Yoshida, R., 2016, In: analytical sciences. 32, 11, p. 1203-1206 4 p.研究成果: Article › 査読
Open Access11 被引用数 (Scopus) -
Design of two complementary copolymers that work as a glue for cell-laden collagen gels
Nishimoto, T., Matsukawa, K., Nagase, K., Kanazawa, H., Akimoto, A. M. & Yoshida, R., 2020 9月 16, In: Chemical Communications. 56, 72, p. 10545-10548 4 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Design of VEGF releasing fiber mat for effective transplantation of cardiomyocyte sheets
Nagase, K. & Kanazawa, H., 2019, In: Drug Delivery System. 34, 3, p. 173-178 6 p.研究成果: Article › 査読
Open Access -
Determination and quantitation of sulfonylurea and urea herbicides in water samples using liquid chromatography with electrospray ionization mass spectrometric detection
Ayano, E., Kanazawa, H., Ando, M. & Nishimura, T., 2004 4月 8, In: Analytica Chimica Acta. 507, 2, p. 211-218 8 p.研究成果: Article › 査読
78 被引用数 (Scopus) -
Determination by asymmetric total synthesis of the absolute configuration of lucilactaene, a cell-cycle inhibitor in p53-transfected cancer cells
Yamaguchi, J., Kakeya, H., Uno, T., Shoji, M., Osada, H. & Hayashi, Y., 2005 5月 13, In: Angewandte Chemie - International Edition. 44, 20, p. 3110-3115 6 p.研究成果: Article › 査読
31 被引用数 (Scopus) -
Determination of acidic saponins in crude drugs by high- performance liquid chromatography on octadecylsilyl porous glass
Kanazawa, H., Nagata, Y., Matsushima, Y., Tomoda, M. & Takai, N., 1993 2月 5, In: Journal of Chromatography A. 630, 1-2, p. 408-414 7 p.研究成果: Article › 査読
20 被引用数 (Scopus) -
Determination of medetomidine, atipamezole and midazolam in pig plasma by liquid chromatography‐mass spectrometry
Kanazawa, H., Nishimura, R., Sasaki, N., Takeuchi, A., Takai, N., Nagata, Y. & Matsushima, Y., 1995 1月 1, In: Biomedical Chromatography. 9, 4, p. 188-191 4 p.研究成果: Article › 査読
27 被引用数 (Scopus) -
Determination of midazolam and its metabolite as a probe for cytochrome P450 3A4 phenotype by liquid chromatography-mass spectrometry
Kanazawa, H., Okada, A., Igarashi, E., Higaki, M., Miyabe, T., Sano, T. & Nishimura, R., 2004 3月 26, In: Journal of Chromatography A. 1031, 1-2, p. 213-218 6 p.研究成果: Article › 査読
30 被引用数 (Scopus) -
Determination of omeprazole and its metabolites in human plasma by liquid chromatography-mass spectrometry
Kanazawa, H., Okada, A., Matsushima, Y., Yokota, H., Okubo, S., Mashige, F. & Nakahara, K., 2002 3月 8, In: Journal of Chromatography A. 949, 1-2, p. 1-9 9 p.研究成果: Article › 査読
50 被引用数 (Scopus) -
Determination of peptides by high-performance liquid chromatography with laser-induced fluorescence detection
Kanazawa, H., Nagatsuka, T., Miyazaki, M. & Matsushima, Y., 1997 2月 28, In: Journal of Chromatography A. 763, 1-2, p. 23-29 7 p.研究成果: Article › 査読
26 被引用数 (Scopus) -
Determination of sedatives and anesthetics in plasma by liquid chromatography-mass spectrometry with a desalting system
Kanazawa, H., Konishi, Y., Matsushima, Y. & Takahashi, T., 1998 2月 27, In: Journal of Chromatography A. 797, 1-2, p. 227-236 10 p.研究成果: Article › 査読
51 被引用数 (Scopus) -
Determination of theophylline and its metabolites in biological samples by liquid chromatography-mass spectrometry
Kanazawa, H., Atsumi, R., Matsushima, Y. & Kizu, J., 2000 2月 18, In: Journal of Chromatography A. 870, 1-2, p. 87-96 10 p.研究成果: Article › 査読
55 被引用数 (Scopus) -
Determination of α-tocopherol and α-tocopherylquinone in rat tissues and plasma by high-performance liquid chromatography with electrochemical detection
Kanazawa, H., Miyata, C., Nagata, Y., Urano, S. & Matsushima, Y., 2000, In: Chemical and Pharmaceutical Bulletin. 48, 10, p. 1462-1466 5 p.研究成果: Article › 査読
Open Access19 被引用数 (Scopus) -
Development of a Fluorescent-Labeled Trapping Reagent to Detect Reactive Acyl Glucuronides
Shibazaki, C., Mashita, O., Takahashi, K., Nakamura, S., Mashino, T. & Ohe, T., 2021 11月 15, In: Chemical Research in Toxicology. 34, 11, p. 2343-2352 10 p.研究成果: Article › 査読
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Development of a novel sulfonate ester-based prodrug strategy
Hanaya, K., Yoshioka, S., Ariyasu, S., Aoki, S., Shoji, M. & Sugai, T., 2016 1月 15, In: Bioorganic and Medicinal Chemistry Letters. 26, 2, p. 545-550 6 p.研究成果: Article › 査読
10 被引用数 (Scopus) -
Development of a sensitive LC–MS/MS method for quantification of linezolid and its primary metabolites in human serum
Souza, E., Felton, J., Crass, R. L., Hanaya, K. & Pai, M. P., 2020 1月 30, In: Journal of Pharmaceutical and Biomedical Analysis. 178, 112968.研究成果: Article › 査読
8 被引用数 (Scopus) -
Development of biodegradable nanoparticles for liver-specific ribavirin delivery
Ishihara, T., Kaneko, K., Ishihara, T. & Mizushima, T., 2014 12月, In: Journal of Pharmaceutical Sciences. 103, 12, p. 4005-4011 7 p.研究成果: Article › 査読
26 被引用数 (Scopus) -
Development of chromatography system organic solvent-free using multi-functional polymers
Nishio, T. & Kanazawa, H., 2010, In: BUNSEKI KAGAKU. 59, 3, p. 163-173 11 p.研究成果: Article › 査読
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Development of fluorescent-labeled trapping reagents based on cysteine to detect soft and hard electrophilic reactive metabolites
Shibazaki, C., Ohe, T., Takahashi, K., Nakamura, S. & Mashino, T., 2021 8月, In: Drug Metabolism And Pharmacokinetics. 39, 100386.研究成果: Article › 査読
3 被引用数 (Scopus) -
Development of intestinal M cells and follicle-associated epithelium is regulated by TRAF6-mediated NF-κB signaling
Kanaya, T., Sakakibara, S., Jinnohara, T., Hachisuka, M., Tachibana, N., Hidano, S., Kobayashi, T., Kimura, S., Iwanaga, T., Nakagawa, T., Katsuno, T., Kato, N., Akiyama, T., Sato, T., Williams, I. R. & Ohno, H., 2018 2月 1, In: Journal of Experimental Medicine. 215, 2, p. 501-519 19 p.研究成果: Article › 査読
Open Access46 被引用数 (Scopus) -
Development of nanocarriers functionalized with stimuli-responsive polymer for controlled cellular uptake
Yamanouchi, T., Katsuyama, N., Hiruta, Y., Ayano, E. & Kanazawa, H., 2018 3月, In: KOBUNSHI RONBUNSHU. 75, 2, p. 116-127 12 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
Development of Novel Diclofenac Analogs Designed to Avoid Metabolic Activation and Hepatocyte Toxicity
Tateishi, Y., Ohe, T., Ogawa, M., Takahashi, K., Nakamura, S. & Mashino, T., 2020 12月 22, In: ACS Omega. 5, 50, p. 32608-32616 9 p.研究成果: Article › 査読
Open Access3 被引用数 (Scopus) -
Development of oral epithelial cell line ROE2 with differentiation potential from transgenic rats harboring temperature-sensitive simian virus 40 large T-antigen gene
Tabuchi, Y., Wada, S., Ikegame, M., Kariya, A., Furusawa, Y., Hoshi, N., Yunoki, T., Suzuki, N., Takasaki, I., Kondo, T. & Suzuki, Y., 2014, In: Experimental Animals. 63, 1, p. 31-44 14 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
Development of temperature-responsive chromatography using functional polymers
Ayano, E. & Kanazawa, H., 2005, In: BUNSEKI KAGAKU. 54, 7, p. 593-603 11 p.研究成果: Article › 査読
4 被引用数 (Scopus) -
Diastereoselective total synthesis of both enantiomers of epolactaene
Hayashi, Y., Kanayama, J., Yamaguchi, J. & Shoji, M., 2002 12月 27, In: Journal of Organic Chemistry. 67, 26, p. 9443-9448 6 p.研究成果: Article › 査読
41 被引用数 (Scopus) -
Diclofenac protects cultured human corneal epithelial cells against hyperosmolarity and ameliorates corneal surface damage in a rat model of dry eye
Sawazaki, R., Ishihara, T., Usui, S., Hayashi, E., Tahara, K., Hoshino, T., Higuchi, A., Nakamura, S., Tsubota, K. & Mizushima, T., 2014 3月 27, In: Investigative Ophthalmology and Visual Science. 55, 4, p. 2547-2556 10 p.研究成果: Article › 査読
30 被引用数 (Scopus) -
Differential effects of the ascorbyl and tocopheryl derivative on the methamphetamine-induced toxic behavior and toxicity
Ito, S., Mori, T., Kanazawa, H. & Sawaguchi, T., 2007 10月 30, In: Toxicology. 240, 1-2, p. 96-110 15 p.研究成果: Article › 査読
16 被引用数 (Scopus) -
Differential induction of cystathionine γ-lyase in the livers and kidneys of mouse dams during gestation and lactation
Akahoshi, N., Izumi, T., Ishizaki, Y. & Ishii, I., 2006, In: Biological and Pharmaceutical Bulletin. 29, 9, p. 1799-1802 4 p.研究成果: Article › 査読
12 被引用数 (Scopus) -
Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS
Yamanaka, T., Tosaki, A., Miyazaki, H., Kurosawa, M., Koike, M., Uchiyama, Y., Maity, S. N., Misawa, H., Takahashi, R., Shimogori, T., Hattori, N. & Nukina, N., 2016 9月 30, In: Scientific reports. 6, 34575.研究成果: Article › 査読
Open Access8 被引用数 (Scopus) -
Different Reaction Modes for the Oxidative Dimerization of Epoxyquinols and Epoxyquinones. Importance of Intermolecular Hydrogen-Bonding
Shoji, M., Imai, H., Shiina, I., Kakeya, H., Osada, H. & Hayashi, Y., 2004 3月 5, In: Journal of Organic Chemistry. 69, 5, p. 1548-1556 9 p.研究成果: Article › 査読
35 被引用数 (Scopus)