法務研究科(法科大学院)

研究成果

1994

Single‐cell Suspension Assay with an MTT End Point Is Useful for Evaluating the Optimal Adjuvant Chemotherapy for Advanced Gastric Cancer

Saikawa, Y., Kubota, T., Furukawa, T., Suto, A., Watanabe, M., Kumai, K., Ishibiki, K. & Kitajima, M., 1994 7, : : Japanese Journal of Cancer Research. 85, 7, p. 762-765 4 p.

研究成果: Article

54 引用 (Scopus)

Synergistic antitumor activity of combination chemotherapy with mitomycin C and cisplatin against human gastric cancer xenografts in nude mice

Saikawa, Y., Kubota, T., Kuo, TH. H., Furukawa, T., Kase, S., Tanino, H., Isobe, Y., Watanabe, M., Ishibiki, K., Arimori, M. & Kitajima, M., 1994 8, : : Journal of Surgical Oncology. 56, 4, p. 242-245 4 p.

研究成果: Article

5 引用 (Scopus)
1993

A metastatic model of human colon cancer constructed using cecal implantation of cancer tissue in nude mice

Furukawa, T., Kubota, T., Watanabe, M., Kuo, T. H., Nishibori, H., Kase, S., Saikawa, Y., Tanino, H., Teramoto, T., Ishibiki, K. & Kitajima, M., 1993 5 1, : : Surgery today. 23, 5, p. 420-423 4 p.

研究成果: Article

25 引用 (Scopus)

A newly developed hexamethylmelamine derivative, SAE9 with both antitumor and aromatase-inhibitory activity

Tanino, H., Kubota, T., Yamada, Y., Koh, J. I., Takeuchi, T., Kase, S., Furukawa, T., Takahashi, M., Fukuda, S., Ogose, N., Komatsu, T., Kato, M., Kitajima, M., Sakurai, T., Naito, Y. & Hoffman, R. M., 1993 1 1, : : Anticancer research. 13, 3, p. 623-626 4 p.

研究成果: Article

5 引用 (Scopus)
100 引用 (Scopus)

A suitable model for experimental liver metastasis of human colon cancer xenografts using mice with severe combined immunodeficiency

Furukawa, T., Kubota, T., Watanabe, M., Nishibori, H., Kuo, TH. H., Saikawa, Y., Kase, S., Tanino, H., Teramoto, T., Ishibiki, K. & Kitajima, M., 1993 1, : : Journal of Surgical Oncology. 52, 1, p. 64-67 4 p.

研究成果: Article

10 引用 (Scopus)

Clinical usefulness of chemosensitivity testing using the mtt assay

Saikawa, Y., Kubota, T., Furukawa, T., Suto, A., Kuo, T. H., Tanino, H., Kase, S., Fujita, S., Yamamoto, T., Ishibiki, K. & Kitajima, M., 1993, : : Annals of Cancer Research and Therapy. 2, 1, p. 143-144 2 p.

研究成果: Article

Colorimetric chemosensitivity testing using sulforhodamine B

Kubota, T., Takahara, T., Nagata, M., Furukawa, T., Kase, S., Tanino, H., Ishibiki, K. & Kitajima, M., 1993 2, : : Journal of Surgical Oncology. 52, 2, p. 83-88 6 p.

研究成果: Article

20 引用 (Scopus)

Different chemo- and endocrino- sensitivity of MCF-7 cells with or without estradiol supplement in vitro

Tanino, H., Kubota, T., Saikawa, Y., Kuo, T. H., Takeuchi, T., Kase, S., Furukawa, T., Kitajima, M., Sakurai, T., Naito, Y. & Hoffman, R. M., 1993 1 1, : : Anticancer research. 13, 4, p. 1219-1221 3 p.

研究成果: Article

1 引用 (Scopus)
26 引用 (Scopus)

Early resection of primary orthotopically-growing human colon tumor in nude mouse prevents liver metastasis: Further evidence for patient-like hematogenous metastatic route

Kuo, T. H., Kubota, T., Watanabe, M., Furukawa, T., Teramoto, T., Ishibiki, K., Kitajima, M. & Hoffman, R. M., 1993 1 1, : : Anticancer research. 13, 2, p. 293-297 5 p.

研究成果: Article

29 引用 (Scopus)

Enhancement of Antitumor Activity of Cisplatin on Human Gastric Cancer Cells in vitro and in vivo by Buthionine Sulfoximine

Saikawa, Y., Kubota, T., Kuo, TH. H., Furukawa, T., Tanino, H., Watanabe, M., Ishibiki, K. & Kitajima, M., 1993 7, : : Japanese Journal of Cancer Research. 84, 7, p. 787-793 7 p.

研究成果: Article

10 引用 (Scopus)

Experimental and clinical studies on the intraperitoneal administration of cis-diamminedichloroplatinum (II) for peritoneal carcinomatosis caused by gastric cancers

Furukawa, T., Kumai, K., Kubota, T., Hirahata, S., Shimizu, H., Matsui, H., Takahara, T., Aizawa, K. I., Shibata, S., Shimada, A., Yoshino, K., Ishibiki, K. & Kitajima, M., 1993 4 1, : : Surgery today. 23, 4, p. 298-306 9 p.

研究成果: Article

9 引用 (Scopus)

Experimental cancer chemotherapy using A liver metastatic model of human colon cancer transplanted into the spleen of severe combined immunodeficient mice

Kuo, TH. H., Kubota, T., Nishibori, H., Watanabe, M., Furukawa, T., Kase, S., Tanino, H., Saikawa, Y., Teramoto, T. & Kitajima, M., 1993 2, : : Journal of Surgical Oncology. 52, 2, p. 92-96 5 p.

研究成果: Article

5 引用 (Scopus)

Growth of human tumor xenografts in nude mice and mice with severe combined immunodeficiency (SCID)

Kubota, T., Yamaguchi, H., Watanabe, M., Yamamoto, T., Takahara, T., Takeuchi, T., Furukawa, T., Kase, S., Kodaira, S., Ishibiki, K. & Kitajima, M., 1993 4 1, : : Surgery today. 23, 4, p. 375-377 3 p.

研究成果: Article

25 引用 (Scopus)

Immunochemotherapy prevents human colon cancer metastasis after orthotopic onplantation of histologically-intact tumor tissue in nude mice

Furukawa, T., Kubota, T., Watanabe, M., Kuo, T. H., Kase, S., Saikawa, Y., Tanino, H., Teramoto, T., Ishibiki, K., Kitajima, M. & Hoffman, R. M., 1993 1 1, : : Anticancer research. 13, 2, p. 287-291 5 p.

研究成果: Article

13 引用 (Scopus)

Interferon beta increases antitumor activity of 5-fluorouracil against human colon carcinoma cells in vitro and in vivo

Kase, S., Kubota, T., Watanabe, M., Furukawa, T., Tanino, H., Ishibiki, K., Teramoto, T. & Kitajima, M., 1993 1 1, : : Anticancer research. 13, 2, p. 369-373 5 p.

研究成果: Article

14 引用 (Scopus)

Modulation by 1-leucovorin of 5-fluorouracil antitumor activity on human gastric carcinoma xenograft in nude mouse: preliminary report

Kase, S., Kubota, T., Furukawa, T., Watanabe, M., Teramoto, T., Ishibiki, K. & Kitajima, M., 1993 6, : : Nippon Geka Gakkai zasshi. 94, 6, 1 p.

研究成果: Article

Nude Mouse Metastatic Models of Human Stomach Cancer Constructed Using Orthotopic Implantation of Histologically Intact Tissue

Furukawa, T., Kubota, T., Watanabe, M. & Kitajima, M., 1993 3, : : Cancer Research. 53, 5, p. 1204-1208 5 p.

研究成果: Article

148 引用 (Scopus)

Orthotopically implanted human colon carcinoma xenografts can metastasize to liver via hematogenous spread: preliminary report

Kuo, T. H., Kubota, T., Watanabe, M., Furukawa, T., Teramoto, T., Ishibiki, K. & Kitajima, M., 1993 2, : : Nippon Geka Gakkai zasshi. 94, 2, 1 p.

研究成果: Article

96 引用 (Scopus)

Significance of in vitro attachment of human colon cancers to extracellular matrix proteins in experimental and clinical liver metastases

Furukawa, T., Watanabe, M., Kubota, T., Kase, S., Fujita, S., Yamamoto, T., Saikawa, Y., Kuo, TH. H., Tanino, H., Kurihara, N., Kawano, Y., Kawamoto, K., Suto, A., Teramoto, T., Ishibiki, K. & Kitajima, M., 1993 5, : : Journal of Surgical Oncology. 53, 1, p. 10-15 6 p.

研究成果: Article

13 引用 (Scopus)

Similarity of serum-tumor pharmacokinetics of antitumor agents

Kubota, T., Inoue, S., Furukawa, T., Ishibiki, K., Kitajima, M., Kawamura, E. & Hoffman, R. M., 1993 1 1, : : Anticancer research. 13, 5 A, p. 1481-1484 4 p.

研究成果: Article

14 引用 (Scopus)

Site-specific chemosensitivity of human small-cell lung carcinoma growing orthotopically compared to subcutaneously in SCID mice: The importance of orthotopic models to obtain relevant drug evaluation data

Kuo, T. H., Kubota, T., Watanabe, M., Furukawa, T., Kase, S., Tanino, H., Saikawa, Y., Ishibiki, K., Kitajima, M. & Hoffman, R. M., 1993 1 1, : : Anticancer research. 13, 3, p. 627-630 4 p.

研究成果: Article

85 引用 (Scopus)

Synergistic antitumor activity of mitomycin C and cisplatin against gastric cancer cells in vitro

Saikawa, Y., Kubota, T., Kuo, TH. H., Kase, S., Furukawa, T., Tanino, H., Ishibiki, K. & Kitajima, M., 1993 10, : : Journal of Surgical Oncology. 54, 2, p. 98-102 5 p.

研究成果: Article

11 引用 (Scopus)

The modulation by L-leucovorin of 5-fluorouracil antitumor activity on human colon carcinoma cells in vitro and in vivo

Kase, S., Kubota, T., Watanabe, M., Takahara, T., Takeuchi, T., Yamaguchi, H., Furukawa, T., Teramoto, T., Kodaira, S., Ishibiki, K. & Kitajima, M., 1993 7 1, : : Surgery today. 23, 7, p. 615-620 6 p.

研究成果: Article

4 引用 (Scopus)

Usefulness of fecal alpha-1-antitrypsin for detection of gastrointestinal bleeding in patients with gastric cancer

Saikawa, Y., Kubota, T., Ogawa, S., Shimada, A., Shibata, S., Furukawa, T., Yamamoto, T., Kumai, K., Yoshino, K., Ishibiki, K., Kitajima, M., Kubota, N. & Kikuchi, T., 1993 1 1, : : Anticancer research. 13, 3, p. 619-622 4 p.

研究成果: Article

1 引用 (Scopus)
1992

A metastatic model of human gastric cancers using orthotopic tissue implantation in nude mice: preliminary report

Furukawa, T., Kubota, T., Watanabe, M., Nishibori, H., Kuo, T. H., Ishibiki, K. & Kitajima, M., 1992 5, : : Nippon Geka Gakkai zasshi. 93, 5, 1 p.

研究成果: Article

2 引用 (Scopus)

Chemosensitivity testing of clinical gastrointestinal cancers using histoculture and the MTT end-point

Furukawa, T., Kubota, T., Watanabe, M., Kase, S., Takahara, T., Yamaguchi, H., Takeuchi, T., Teramoto, T., Ishibiki, K., Kitajima, M. & Hoffman, R. M., 1992 1 1, : : Anticancer research. 12, 5, p. 1377-1382 6 p.

研究成果: Article

30 引用 (Scopus)

High Human IgG Levels in Severe Combined Immunodeficient Mouse Reconstituted with Human Splenic Tissues from Patients with Gastric Cancer

Kubota, T., Yamaguchi, H., Watanabe, M., Yamamoto, T., Takahara, T., Takeuchi, T., Furukawa, T., Kase, S., Kodaira, S., Ishibiki, K. & Kitajima, M., 1992 3, : : Japanese Journal of Cancer Research. 83, 3, p. 300-303 4 p.

研究成果: Article

6 引用 (Scopus)

High in vitro‐in vivo correlation of drug response using sponge‐gel‐supported three‐dimensional histoculture and the MTT end point

Furukawa, T., Kubota, T., Watanabe, M., Takahara, T., Yamaguchi, H., Takeuchi, T., Kase, S., Kodaira, S., Ishibiki, K., Kitajima, M. & Hoffman, R. M., 1992 5 28, : : International Journal of Cancer. 51, 3, p. 489-498 10 p.

研究成果: Article

77 引用 (Scopus)

Increased drug resistance of cultured human cancer cell lines in three‐dimensional cellular growth assay using collagen gel matrix

Furukawa, T., Kubota, T., Watanabe, M., Kase, S., Saikawa, Y., Nishibori, H., Kuo, TH. H., Kodaira, S., Ishibiki, K. & Kitajima, M., 1992 2, : : Journal of Surgical Oncology. 49, 2, p. 86-92 7 p.

研究成果: Article

11 引用 (Scopus)

Modulation by l-Leucovorin of 1-Hexylcarbamoyl-5-Fluorouracil antitumor activity on human gastric and colon carcinomas serially transplanted into nude mice

Kubota, T., Kase, S., Furukawa, T., Tanino, H., Kuo, T. H., Saikawa, Y., Nishibori, H., Ishibiki, K., Kitajima, M., Mabuchi, K. & Hirata, H., 1992 1 1, : : Anticancer research. 12, 5, p. 1549-1553 5 p.

研究成果: Article

2 引用 (Scopus)

Orthotopic reconstitution of human small-cell lung carcinoma after intravenous transplantation in SCID mice

Kuo, T. H., Kubota, T., Watanabe, M., Furukawa, T., Kase, S., Tanino, H., Nishibori, H., Saikawa, Y., Teramoto, T., Ihsibiki, K., Kitajima, M. & Hoffman, R. M., 1992 1 1, : : Anticancer research. 12, 5, p. 1407-1410 4 p.

研究成果: Article

30 引用 (Scopus)
8 引用 (Scopus)

Targeting cancer chemotherapy using a monoclonal antibody (NCC‐LU‐243) conjugated with mitomycin C

Kubota, T., Yamamoto, T., Takahara, T., Furukawa, T., Ishibiki, K., Kitajima, M., Shida, Y. & Nakatsubo, H., 1992 10, : : Journal of Surgical Oncology. 51, 2, p. 75-80 6 p.

研究成果: Article

7 引用 (Scopus)
1991

Antitumor activity and toxicity of KB-5424 R, a newly developed antitumor platinum compound

Yamaguchi, H., Kubota, T., Takahara, T., Takeuchi, T., Furukawa, T., Kase, S., Josui, K., Kadaira, S., Ishibiki, K., Abe, O., Ikeda, Y., Matsui, M. & Ugumori, N., 1991, : : Japanese Journal of Cancer and Chemotherapy. 18, 7, p. 1135-1141 7 p.

研究成果: Article

Clinical usefulness of chemosensitivity testing using the MTT assay

Furukawa, T., Kubota, T., Suto, A., Takahara, T., Yamaguchi, H., Takeuchi, T., Kase, S., Kodaira, S., Ishibiki, K. & Kitajima, M., 1991 11, : : Journal of Surgical Oncology. 48, 3, p. 188-193 6 p.

研究成果: Article

66 引用 (Scopus)

Establishment of transplantable human colon cancer cell lines, chemosensitivity of these colon carcinomas and the serially transplantable strains with MTT assay

Kase, S., Kubota, T., Furukawa, T., Yamaguchi, H., Takeuchi, T., Takahara, T., Suto, A., Kodaira, S. & Ishibiki, K., 1991 1 1, : : Japanese Journal of Cancer and Chemotherapy. 18, 13, p. 2247-2253 7 p.

研究成果: Article

2 引用 (Scopus)

Growth chamber assay, a novel chemosensitivity test which eliminates normal stromal cells

Tetsuya, T., Tetsuro, K., Hiroshi, Y., Touru, T., Toshiharu, F., Suguru, K., Susumu, K., Kyuya, I., Osahiko, A., Hirokazu, Y., Masatoshi, N. & Motonobu, I., 1991 1 1, : : Japanese Journal of Cancer and Chemotherapy. 18, 4, p. 547-554 8 p.

研究成果: Article

2 引用 (Scopus)