大学院研究科

1994

Liver Metastatic Model of Human Colon Cancer Constructed by Orthotopic Onplantation A Suitable Model for Experimental Immunochemotherapy

Kuo, T. H., Kubota, T., Watanabe, M., Furukawa, T., Teramoto, T. & Kitajima, M., 1994, In: the japanese journal of gastroenterological surgery. 27, 4, p. 994-997 4 p.

研究成果: Article › 査読

Paradoxical Enhancement of Tumor Growth in Mice with Severe Combined Immunodeficiency which Produce a Human Immunoglobulin G Reactive against Tumor Cells

Furukawa, T., Watanabe, M., Kubota, T. & Kitajima, M., 1994 1月, In: Japanese Journal of Cancer Research. 85, 1, p. 72-79 8 p.

研究成果: Article › 査読

Open Access

Single‐cell Suspension Assay with an MTT End Point Is Useful for Evaluating the Optimal Adjuvant Chemotherapy for Advanced Gastric Cancer

Saikawa, Y., Kubota, T., Furukawa, T., Suto, A., Watanabe, M., Kumai, K., Ishibiki, K. & Kitajima, M., 1994 7月, In: Japanese Journal of Cancer Research. 85, 7, p. 762-765 4 p.

研究成果: Article › 査読

54 被引用数 (Scopus)

Synergistic antitumor activity of combination chemotherapy with mitomycin C and cisplatin against human gastric cancer xenografts in nude mice

Saikawa, Y., Kubota, T., Kuo, TH. H., Furukawa, T., Kase, S., Tanino, H., Isobe, Y., Watanabe, M., Ishibiki, K., Arimori, M. & Kitajima, M., 1994 8月, In: Journal of Surgical Oncology. 56, 4, p. 242-245 4 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

1993

A metastatic model of human colon cancer constructed using cecal implantation of cancer tissue in nude mice

Furukawa, T., Kubota, T., Watanabe, M., Kuo, T. H., Nishibori, H., Kase, S., Saikawa, Y., Tanino, H., Teramoto, T., Ishibiki, K. & Kitajima, M., 1993 5月 1, In: Surgery today. 23, 5, p. 420-423 4 p.

研究成果: Article › 査読

25 被引用数 (Scopus)

A newly developed hexamethylmelamine derivative, SAE9 with both antitumor and aromatase-inhibitory activity

Tanino, H., Kubota, T., Yamada, Y., Koh, J. I., Takeuchi, T., Kase, S., Furukawa, T., Takahashi, M., Fukuda, S., Ogose, N., Komatsu, T., Kato, M., Kitajima, M., Sakurai, T., Naito, Y. & Hoffman, R. M., 1993 1月 1, In: Anticancer research. 13, 3, p. 623-626 4 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

A Novel “Patient-like” Treatment Model of Human Pancreatic Cancer Constructed Using Orthotopic Transplantation of Histologically Intact Human Tumor Tissue in Nude Mice

Furukawa, T., Kubota, T., Watanabe, M., Kitajima, M. & Hoffman, R. M., 1993 7月, In: Cancer Research. 53, 13, p. 3070-3072 3 p.

研究成果: Article › 査読

106 被引用数 (Scopus)

A suitable model for experimental liver metastasis of human colon cancer xenografts using mice with severe combined immunodeficiency

Furukawa, T., Kubota, T., Watanabe, M., Nishibori, H., Kuo, TH. H., Saikawa, Y., Kase, S., Tanino, H., Teramoto, T., Ishibiki, K. & Kitajima, M., 1993 1月, In: Journal of Surgical Oncology. 52, 1, p. 64-67 4 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Clinical usefulness of chemosensitivity testing using the mtt assay

Saikawa, Y., Kubota, T., Furukawa, T., Suto, A., Kuo, T. H., Tanino, H., Kase, S., Fujita, S., Yamamoto, T., Ishibiki, K. & Kitajima, M., 1993, In: Annals of Cancer Research and Therapy. 2, 1, p. 143-144 2 p.

研究成果: Article › 査読

Colorimetric chemosensitivity testing using sulforhodamine B

Kubota, T., Takahara, T., Nagata, M., Furukawa, T., Kase, S., Tanino, H., Ishibiki, K. & Kitajima, M., 1993 2月, In: Journal of Surgical Oncology. 52, 2, p. 83-88 6 p.

研究成果: Article › 査読

20 被引用数 (Scopus)

Different chemo- and endocrino- sensitivity of MCF-7 cells with or without estradiol supplement in vitro

Tanino, H., Kubota, T., Saikawa, Y., Kuo, T. H., Takeuchi, T., Kase, S., Furukawa, T., Kitajima, M., Sakurai, T., Naito, Y. & Hoffman, R. M., 1993 1月 1, In: Anticancer research. 13, 4, p. 1219-1221 3 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Differential chemosensitivity of local and metastatic human gastric cancer after orthotopic transplantation of histologically intact tumor tissue in nude mice

Furukawa, T., Kubota, T., Watanabe, M., Kuo, TH. H., Kitajima, M. & Hoffman, R. M., 1993 5月 28, In: International Journal of Cancer. 54, 3, p. 397-401 5 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

Early resection of primary orthotopically-growing human colon tumor in nude mouse prevents liver metastasis: Further evidence for patient-like hematogenous metastatic route

Kuo, T. H., Kubota, T., Watanabe, M., Furukawa, T., Teramoto, T., Ishibiki, K., Kitajima, M. & Hoffman, R. M., 1993, In: Anticancer research. 13, 2, p. 293-297 5 p.

研究成果: Article › 査読

29 被引用数 (Scopus)

Enhancement of Antitumor Activity of Cisplatin on Human Gastric Cancer Cells in vitro and in vivo by Buthionine Sulfoximine

Saikawa, Y., Kubota, T., Kuo, TH. H., Furukawa, T., Tanino, H., Watanabe, M., Ishibiki, K. & Kitajima, M., 1993 7月, In: Japanese Journal of Cancer Research. 84, 7, p. 787-793 7 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Experimental and clinical studies on the intraperitoneal administration of cis-diamminedichloroplatinum (II) for peritoneal carcinomatosis caused by gastric cancers

Furukawa, T., Kumai, K., Kubota, T., Hirahata, S., Shimizu, H., Matsui, H., Takahara, T., Aizawa, K. I., Shibata, S., Shimada, A., Yoshino, K., Ishibiki, K. & Kitajima, M., 1993 4月 1, In: Surgery today. 23, 4, p. 298-306 9 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Experimental cancer chemotherapy using A liver metastatic model of human colon cancer transplanted into the spleen of severe combined immunodeficient mice

Kuo, TH. H., Kubota, T., Nishibori, H., Watanabe, M., Furukawa, T., Kase, S., Tanino, H., Saikawa, Y., Teramoto, T. & Kitajima, M., 1993 2月, In: Journal of Surgical Oncology. 52, 2, p. 92-96 5 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Growth of human tumor xenografts in nude mice and mice with severe combined immunodeficiency (SCID)

Kubota, T., Yamaguchi, H., Watanabe, M., Yamamoto, T., Takahara, T., Takeuchi, T., Furukawa, T., Kase, S., Kodaira, S., Ishibiki, K. & Kitajima, M., 1993 4月 1, In: Surgery today. 23, 4, p. 375-377 3 p.

研究成果: Article › 査読

25 被引用数 (Scopus)

High clinical predictability of histoculture drug response assay (HDRA) for drug-sensitivity of cancer of the digestive organs

Kubota, T., Furukawa, T. & Kitajima, M., 1993 1月 1, In: Japanese Journal of Cancer and Chemotherapy. 20, 4, p. 461-466 6 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Immunochemotherapy prevents human colon cancer metastasis after orthotopic onplantation of histologically-intact tumor tissue in nude mice

Furukawa, T., Kubota, T., Watanabe, M., Kuo, T. H., Kase, S., Saikawa, Y., Tanino, H., Teramoto, T., Ishibiki, K., Kitajima, M. & Hoffman, R. M., 1993 1月 1, In: Anticancer research. 13, 2, p. 287-291 5 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Interferon beta increases antitumor activity of 5-fluorouracil against human colon carcinoma cells in vitro and in vivo

Kase, S., Kubota, T., Watanabe, M., Furukawa, T., Tanino, H., Ishibiki, K., Teramoto, T. & Kitajima, M., 1993 1月 1, In: Anticancer research. 13, 2, p. 369-373 5 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Modulation by 1-leucovorin of 5-fluorouracil antitumor activity on human gastric carcinoma xenograft in nude mouse: preliminary report

Kase, S., Kubota, T., Furukawa, T., Watanabe, M., Teramoto, T., Ishibiki, K. & Kitajima, M., 1993 6月, In: Nippon Geka Gakkai zasshi. 94, 6, 1 p.

研究成果: Article › 査読

Nude Mouse Metastatic Models of Human Stomach Cancer Constructed Using Orthotopic Implantation of Histologically Intact Tissue

Furukawa, T., Kubota, T., Watanabe, M. & Kitajima, M., 1993 3月, In: Cancer Research. 53, 5, p. 1204-1208 5 p.

研究成果: Article › 査読

157 被引用数 (Scopus)

Orthotopically implanted human colon carcinoma xenografts can metastasize to liver via hematogenous spread: preliminary report

Kuo, T. H., Kubota, T., Watanabe, M., Furukawa, T., Teramoto, T., Ishibiki, K. & Kitajima, M., 1993 2月, In: Nippon Geka Gakkai zasshi. 94, 2, 1 p.

研究成果: Article › 査読

Orthotopic transplantation of histologically intact clinical specimens of stomach cancer to nude mice: Correlation of metastatic sites in mouse and individual patient donors

Furukawa, T., Kubota, T., Watanabe, M., Kitajima, M. & Hoffman, R. M., 1993 2月 20, In: International Journal of Cancer. 53, 4, p. 608-612 5 p.

研究成果: Article › 査読

111 被引用数 (Scopus)

Significance of in vitro attachment of human colon cancers to extracellular matrix proteins in experimental and clinical liver metastases

Furukawa, T., Watanabe, M., Kubota, T., Kase, S., Fujita, S., Yamamoto, T., Saikawa, Y., Kuo, TH. H., Tanino, H., Kurihara, N., Kawano, Y., Kawamoto, K., Suto, A., Teramoto, T., Ishibiki, K. & Kitajima, M., 1993 5月, In: Journal of Surgical Oncology. 53, 1, p. 10-15 6 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Similarity of serum-tumor pharmacokinetics of antitumor agents

Kubota, T., Inoue, S., Furukawa, T., Ishibiki, K., Kitajima, M., Kawamura, E. & Hoffman, R. M., 1993 1月 1, In: Anticancer research. 13, 5 A, p. 1481-1484 4 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Site-specific chemosensitivity of human small-cell lung carcinoma growing orthotopically compared to subcutaneously in SCID mice: The importance of orthotopic models to obtain relevant drug evaluation data

Kuo, T. H., Kubota, T., Watanabe, M., Furukawa, T., Kase, S., Tanino, H., Saikawa, Y., Ishibiki, K., Kitajima, M. & Hoffman, R. M., 1993 1月 1, In: Anticancer research. 13, 3, p. 627-630 4 p.

研究成果: Article › 査読

89 被引用数 (Scopus)

Super high definition image communications - a platform for media integration -

Ono, S. & Ohta, N., 1993 6月 1, In: IEICE Transactions on Communications. E76-B, 6, p. 599-608 10 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Synergistic antitumor activity of mitomycin C and cisplatin against gastric cancer cells in vitro

Saikawa, Y., Kubota, T., Kuo, TH. H., Kase, S., Furukawa, T., Tanino, H., Ishibiki, K. & Kitajima, M., 1993 10月, In: Journal of Surgical Oncology. 54, 2, p. 98-102 5 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

The modulation by L-leucovorin of 5-fluorouracil antitumor activity on human colon carcinoma cells in vitro and in vivo

Kase, S., Kubota, T., Watanabe, M., Takahara, T., Takeuchi, T., Yamaguchi, H., Furukawa, T., Teramoto, T., Kodaira, S., Ishibiki, K. & Kitajima, M., 1993 7月 1, In: Surgery today. 23, 7, p. 615-620 6 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Usefulness of fecal alpha-1-antitrypsin for detection of gastrointestinal bleeding in patients with gastric cancer

Saikawa, Y., Kubota, T., Ogawa, S., Shimada, A., Shibata, S., Furukawa, T., Yamamoto, T., Kumai, K., Yoshino, K., Ishibiki, K., Kitajima, M., Kubota, N. & Kikuchi, T., 1993 1月 1, In: Anticancer research. 13, 3, p. 619-622 4 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

1992

All-digital super high definition images

Ono, S., Ohta, N. & Aoyama, T., 1992 8月, In: Signal Processing: Image Communication. 4, 4-5, p. 429-444 16 p.

研究成果: Article › 査読

39 被引用数 (Scopus)

A metastatic model of human gastric cancers using orthotopic tissue implantation in nude mice: preliminary report

Furukawa, T., Kubota, T., Watanabe, M., Nishibori, H., Kuo, T. H., Ishibiki, K. & Kitajima, M., 1992 5月, In: Nippon Geka Gakkai zasshi. 93, 5, 1 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Chemosensitivity testing of clinical gastrointestinal cancers using histoculture and the MTT end-point

Furukawa, T., Kubota, T., Watanabe, M., Kase, S., Takahara, T., Yamaguchi, H., Takeuchi, T., Teramoto, T., Ishibiki, K., Kitajima, M. & Hoffman, R. M., 1992 1月 1, In: Anticancer research. 12, 5, p. 1377-1382 6 p.

研究成果: Article › 査読

31 被引用数 (Scopus)

High Human IgG Levels in Severe Combined Immunodeficient Mouse Reconstituted with Human Splenic Tissues from Patients with Gastric Cancer

Kubota, T., Yamaguchi, H., Watanabe, M., Yamamoto, T., Takahara, T., Takeuchi, T., Furukawa, T., Kase, S., Kodaira, S., Ishibiki, K. & Kitajima, M., 1992 3月, In: Japanese Journal of Cancer Research. 83, 3, p. 300-303 4 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

High in vitro‐in vivo correlation of drug response using sponge‐gel‐supported three‐dimensional histoculture and the MTT end point

Furukawa, T., Kubota, T., Watanabe, M., Takahara, T., Yamaguchi, H., Takeuchi, T., Kase, S., Kodaira, S., Ishibiki, K., Kitajima, M. & Hoffman, R. M., 1992 5月 28, In: International Journal of Cancer. 51, 3, p. 489-498 10 p.

研究成果: Article › 査読

79 被引用数 (Scopus)

Increased drug resistance of cultured human cancer cell lines in three‐dimensional cellular growth assay using collagen gel matrix

Furukawa, T., Kubota, T., Watanabe, M., Kase, S., Saikawa, Y., Nishibori, H., Kuo, TH. H., Kodaira, S., Ishibiki, K. & Kitajima, M., 1992 2月, In: Journal of Surgical Oncology. 49, 2, p. 86-92 7 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Modulation by l-Leucovorin of 1-Hexylcarbamoyl-5-Fluorouracil antitumor activity on human gastric and colon carcinomas serially transplanted into nude mice

Kubota, T., Kase, S., Furukawa, T., Tanino, H., Kuo, T. H., Saikawa, Y., Nishibori, H., Ishibiki, K., Kitajima, M., Mabuchi, K. & Hirata, H., 1992 1月 1, In: Anticancer research. 12, 5, p. 1549-1553 5 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Orthotopic reconstitution of human small-cell lung carcinoma after intravenous transplantation in SCID mice

Kuo, T. H., Kubota, T., Watanabe, M., Furukawa, T., Kase, S., Tanino, H., Nishibori, H., Saikawa, Y., Teramoto, T., Ihsibiki, K., Kitajima, M. & Hoffman, R. M., 1992 1月 1, In: Anticancer research. 12, 5, p. 1407-1410 4 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

Production of Human Immunoglobulin G Reactive against Human Cancer in Tumor‐bearing Mice with Severe Combined Immunodeficiency Reconstituted with Human Splenic Tissues

Furukawa, T., Watanabe, M., Kubota, T., Yamaguchi, H., Teramoto, T., Ishibiki, K. & Kitajima, M., 1992 8月, In: Japanese Journal of Cancer Research. 83, 8, p. 894-898 5 p.

研究成果: Article › 査読

Open Access

8 被引用数 (Scopus)

Rapid Communication - Quantitative analysis of intercellular communication in colon cancer cells (Caco-2) by the scrape-loading/dye transfer assay

Hara, A., Hibil, T., Yoshioka, M., Hayashi, A., Toda, K., Suzuki, T., Kameda, Y., Ueda, F., Watanabe, M. & Tsuchiya, M., 1992 8月 1, In: Gastroenterologia Japonica. 27, 4, 1 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Targeting cancer chemotherapy using a monoclonal antibody (NCC‐LU‐243) conjugated with mitomycin C

Kubota, T., Yamamoto, T., Takahara, T., Furukawa, T., Ishibiki, K., Kitajima, M., Shida, Y. & Nakatsubo, H., 1992 10月, In: Journal of Surgical Oncology. 51, 2, p. 75-80 6 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

1991

Antitumor activity and toxicity of KB-5424 R, a newly developed antitumor platinum compound

Yamaguchi, H., Kubota, T., Takahara, T., Takeuchi, T., Furukawa, T., Kase, S., Josui, K., Kadaira, S., Ishibiki, K., Abe, O., Ikeda, Y., Matsui, M. & Ugumori, N., 1991, In: Japanese Journal of Cancer and Chemotherapy. 18, 7, p. 1135-1141 7 p.

研究成果: Article › 査読

Clinical usefulness of chemosensitivity testing using the MTT assay

Furukawa, T., Kubota, T., Suto, A., Takahara, T., Yamaguchi, H., Takeuchi, T., Kase, S., Kodaira, S., Ishibiki, K. & Kitajima, M., 1991 11月, In: Journal of Surgical Oncology. 48, 3, p. 188-193 6 p.

研究成果: Article › 査読

68 被引用数 (Scopus)

Establishment of transplantable human colon cancer cell lines, chemosensitivity of these colon carcinomas and the serially transplantable strains with MTT assay

Kase, S., Kubota, T., Furukawa, T., Yamaguchi, H., Takeuchi, T., Takahara, T., Suto, A., Kodaira, S. & Ishibiki, K., 1991 1月 1, In: Japanese Journal of Cancer and Chemotherapy. 18, 13, p. 2247-2253 7 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Growth chamber assay, a novel chemosensitivity test which eliminates normal stromal cells

Tetsuya, T., Tetsuro, K., Hiroshi, Y., Touru, T., Toshiharu, F., Suguru, K., Susumu, K., Kyuya, I., Osahiko, A., Hirokazu, Y., Masatoshi, N. & Motonobu, I., 1991, In: Japanese Journal of Cancer and Chemotherapy. 18, 4, p. 547-554 8 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Layered coding for ATM based video distribution systems

Nomura, M., Fujii, T. & Ohta, N., 1991 9月, In: Signal Processing: Image Communication. 3, 4, p. 301-311 11 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

1990

In vitro anticolon antibody production by mucosal or peripheral blood lymphocytes from patients with ulcerative colitis

Hibi, T., Ohara, M., Toda, K., Hara, A., Ogata, H., Iwao, Y., Watanabe, N., Watanabe, M., Hamada, Y., Kobayashi, K., Aiso, S., Tsuchiya, M., Ohara, M., Toda, K. & Watanabe, N., 1990, In: Gut. 31, 12, p. 1371-1376 6 p.

研究成果: Article › 査読

Open Access

49 被引用数 (Scopus)

Scheduling methods for a low-bit-rate speech coding algorithm (ATC-VQ) on a multicomputer-type DSP system

Sawabe, T., Suzuki, J., Ohta, N. & Ono, S., 1990 6月, In: Electronics and Communications in Japan, Part III: Fundamental Electronic Science (English translation of Denshi Tsushin Gakkai Ronbunshi). 73, 6, p. 78-88 11 p.

研究成果: Article › 査読

1989

Basic characteristics of variable rate interframe video coding

Nomura, M., Fujii, T. & Ohta, N., 1989 9月, In: Electronics and Communications in Japan, Part I: Communications (English translation of Denshi Tsushin Gakkai Ronbunshi). 72, 9, p. 92-102 11 p.

研究成果: Article › 査読

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