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研究成果 1999 2019

  • 703 引用
  • 15 h指数
  • 44 Article
  • 5 Review article
  • 2 Comment/debate
  • 1 Chapter
フィルター
Article
2019

Establishment and characterization of a new malignant peritoneal mesothelioma cell line, KOG-1, from the ascitic fluid of a patient with pemetrexed chemotherapy resistance

Akahane, T., Hirasawa, A., Imoto, I., Okubo, A., Itoh, M., Nanki, Y., Yoshihama, T., Tominaga, E. & Aoki, D., 2019 1 1, (Accepted/In press) : : Human Cell.

研究成果: Article

Pemetrexed
Ascitic Fluid
Drug Therapy
Cell Line
Contact Inhibition
公開
Uterine Diseases
Aminolevulinic Acid
Neoplasms
Sensitivity and Specificity
Endometrial Hyperplasia
1 引用 (Scopus)

Is antidyslipidemic statin use for cancer prevention a promising drug repositioning approach?

Kobayashi, Y., Banno, K., Kunitomi, H., Nagai, S., Takahashi, T., Anko, M., Iijima, M., Takeda, T., Matoba, Y., Nakamura, K., Tsuji, K., Tominaga, E. & Aoki, D., 2019 11 1, : : European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). 28, 6, p. 562-567 6 p.

研究成果: Article

Drug Repositioning
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Pharmaceutical Preparations
Neoplasms
Molecular Mechanisms of Pharmacological Action

Mutations of RAS genes in endometrial polyps

Takeda, T., Banno, K., Kobayashi, Y., Adachi, M., Yanokura, M., Tominaga, E., Kosaki, K. & Aoki, D., 2019 1 1, : : Oncology reports. 42, 6, p. 2303-2308 6 p.

研究成果: Article

公開
Polyps
Mutation
Genes
Adenomyoma
Laser Capture Microdissection
2018
4 引用 (Scopus)
Hereditary Nonpolyposis Colorectal Neoplasms
Ovarian Neoplasms
DNA Mismatch Repair
Methylation
Mutation

Warburg effect in Gynecologic cancers

Kobayashi, Y., Banno, K., Kunitomi, H., Takahashi, T., Takeda, T., Nakamura, K., Tsuji, K., Tominaga, E. & Aoki, D., 2018 1 1, (Accepted/In press) : : Journal of Obstetrics and Gynaecology Research.

研究成果: Article

Glycolysis
Neoplasms
Oxidative Phosphorylation
Glucose
Lactic Acid
2017
1 引用 (Scopus)

Clinical utility of a self-administered questionnaire for assessment of hereditary gynecologic cancer

Masuda, K., Hirasawa, A., Irie-Kunitomi, H., Akahane, T., Ueki, A., Kobayashi, Y., Yamagami, W., Nomura, H., Kataoka, F., Tominaga, E., Banno, K., Susumu, N. & Aoki, D., 2017 5 1, : : Japanese Journal of Clinical Oncology. 47, 5, p. 401-406 6 p., hyx019.

研究成果: Article

Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms
Endometrial Neoplasms
Ovarian Neoplasms
Surveys and Questionnaires
13 引用 (Scopus)

Drug repositioning of mevalonate pathway inhibitors as antitumor agents for ovarian cancer

Kobayashi, Y., Kashima, H., Rahmanto, Y. S., Banno, K., Yu, Y., Matoba, Y., Watanabe, K., Iijima, M., Takeda, T., Kunitomi, H., Iida, M., Adachi, M., Nakamura, K., Tsuji, K., Masuda, K., Nomura, H., Tominaga, E. & Aoki, D., 2017 1 1, : : Oncotarget. 8, 42, p. 72147-72156 10 p.

研究成果: Article

Drug Repositioning
Mevalonic Acid
Antineoplastic Agents
Ovarian Neoplasms
Diphosphonates
2 引用 (Scopus)

UGT1A1 polymorphism as a prognostic indicator of stage I ovarian clear cell carcinoma patients treated with irinotecan

Yoshihama, T., Hirasawa, A., Nomura, H., Akahane, T., Nanki, Y., Yamagami, W., Kataoka, F., Tominaga, E., Susumu, N., Mushiroda, T. & Aoki, D., 2017 2 1, : : Japanese Journal of Clinical Oncology. 47, 2, p. 170-174 5 p.

研究成果: Article

irinotecan
Carcinoma
Genotype
Disease-Free Survival
Recurrence
2016
55 引用 (Scopus)

ARID1A gene mutation in ovarian and endometrial cancers (Review)

Takeda, T., Banno, K., Okawa, R., Yanokura, M., Iijima, M., Iriekunitomi, H., Nakamura, K., Iida, M., Adachi, M., Umene, K., Nogami, Y., Masuda, K., Kobayashi, Y., Tominaga, E. & Aoki, D., 2016 2 1, : : Oncology Reports. 35, 2, p. 607-613 7 p.

研究成果: Article

Endometrial Neoplasms
Ovarian Neoplasms
Mutation
Genes
Proteins
17 引用 (Scopus)

Metformin: A candidate for the treatment of gynecological tumors based on drug repositioning (Review)

Irie, H., Banno, K., Yanokura, M., Iida, M., Adachi, M., Nakamura, K., Umene, K., Nogami, Y., Masuda, K., Kobayashi, Y., Tominaga, E. & Aoki, D., 2016 2 1, : : Oncology Letters. 11, 2, p. 1287-1293 7 p.

研究成果: Article

Drug Repositioning
Metformin
Neoplasms
Clinical Trials
Breast Neoplasms
5 引用 (Scopus)

Methylation analysis of DNA mismatch repair genes using DNA derived from the peripheral blood of patients with endometrial cancer: Epimutation in endometrial carcinogenesis

Takeda, T., Banno, K., Yanokura, M., Adachi, M., Iijima, M., Kunitomi, H., Nakamura, K., Iida, M., Nogami, Y., Umene, K., Masuda, K., Kobayashi, Y., Yamagami, W., Hirasawa, A., Tominaga, E., Susumu, N. & Aoki, D., 2016 10 14, : : Genes. 7, 10, 86.

研究成果: Article

DNA Mismatch Repair
Endometrial Neoplasms
Methylation
Carcinogenesis
Microsatellite Instability
2015
14 引用 (Scopus)

Aurora kinase A has a significant role as a therapeutic target and clinical biomarker in endometrial cancer

Umene, K., Yanokura, M., Banno, K., Irie, H., Adachi, M., Iida, M., Nakamura, K., Nogami, Y., Masuda, K., Kobayashi, Y., Tominaga, E. & Aoki, D., 2015 4 1, : : International Journal of Oncology. 46, 4, p. 1498-1506 9 p.

研究成果: Article

Aurora Kinases
Aurora Kinase A
Endometrial Neoplasms
Biomarkers
Paclitaxel
22 引用 (Scopus)

Clinicopathologic analysis with immunohistochemistry for DNA mismatch repair protein expression in synchronous primary endometrial and ovarian cancers

Kobayashi, Y., Nakamura, K., Nomura, H., Banno, K., Irie, H., Adachi, M., Iida, M., Umene, K., Nogami, Y., Masuda, K., Kisu, I., Ueki, A., Yamagami, W., Kataoka, F., Hirasawa, A., Tominaga, E., Susumu, N. & Aoki, D., 2015 3 10, : : International Journal of Gynecological Cancer. 25, 3, p. 440-446 7 p.

研究成果: Article

DNA Mismatch Repair
Endometrial Neoplasms
Ovarian Neoplasms
Immunohistochemistry
Neoplasms
16 引用 (Scopus)
Drug Repositioning
tumor
Tumors
cancer
drug
2 引用 (Scopus)

Effectiveness of third-line chemotherapy in recurrent ovarian cancer patients

Yoshihama, T., Chiyoda, T., Kataoka, F., Nomura, H., Iguchi, Y., Hashimoto, S., Yamagami, W., Tominaga, E., Susumu, N., Tsuda, H. & Aoki, D., 2015, : : European Journal of Gynaecological Oncology. 36, 4, p. 424-427 4 p.

研究成果: Article

Ovarian Neoplasms
Drug Therapy
Therapeutics
Survival
Carboplatin
32 引用 (Scopus)
Endometrial Neoplasms
MicroRNAs
microRNA
neoplasms
biomarkers
1 引用 (Scopus)

Osteoporosis is less frequent in endometrial cancer survivors with hypertriglyceridemia

Hirasawa, A., Makita, K., Akahane, T., Yamagami, W., Makabe, T., Yokota, M., Horiba, Y., Ogawa, M., Yanamoto, S., Deshimaru, R., Tominaga, E., Banno, K., Susumu, N. & Aoki, D., 2015 1 1, : : Japanese Journal of Clinical Oncology. 45, 1, p. 127-131 5 p., hyu164.

研究成果: Article

Hypertriglyceridemia
Endometrial Neoplasms
Osteoporosis
Survivors
Dyslipidemias
25 引用 (Scopus)
Endometrial Neoplasms
Uterine Cervical Neoplasms
Lymph Nodes
Neoplasm Metastasis
Deoxyglucose
2014
23 引用 (Scopus)

Application of FDG-PET in cervical cancer and endometrial cancer: Utility and future prospects

Nogami, Y., Iida, M., Banno, K., Kisu, I., Adachi, M., Nakamura, K., Umene, K., Masuda, K., Tominaga, E., Tanaka, K. & Aoki, D., 2014 2 1, : : Anticancer Research. 34, 2, p. 585-592 8 p.

研究成果: Article

Endometrial Neoplasms
Uterine Cervical Neoplasms
Positron-Emission Tomography
Glucose
Uterine Neoplasms
40 引用 (Scopus)

Application of MicroRNA in diagnosis and treatment of ovarian cancer

Banno, K., Yanokura, M., Iida, M., Adachi, M., Nakamura, K., Nogami, Y., Umene, K., Masuda, K., Kisu, I., Nomura, H., Kataoka, F., Tominaga, E. & Aoki, D., 2014, : : BioMed Research International. 2014, 232817.

研究成果: Article

MicroRNAs
Ovarian Neoplasms
Therapeutics
Ribonuclease III
Neoplasm Metastasis
6 引用 (Scopus)
Streptococcal Infections
Septic Shock
Uterine Cervical Neoplasms
Drug Therapy
Myalgia
7 引用 (Scopus)

Family history and BRCA1/BRCA2 status among Japanese ovarian cancer patients and occult cancer in a BRCA1 mutant case

Hirasawa, A., Masuda, K., Akahane, T., Ueki, A., Yokota, M., Tsuruta, T., Nomura, H., Kataoka, F., Tominaga, E., Banno, K., Makita, K., Susumu, N., Sugano, K., Kosaki, K., Kameyama, K. & Aoki, D., 2014 1, : : Japanese Journal of Clinical Oncology. 44, 1, p. 49-56 8 p., hyt171.

研究成果: Article

Ovarian Neoplasms
Fallopian Tube Neoplasms
Neoplasms
Mutation
Hereditary Breast and Ovarian Cancer Syndrome
9 引用 (Scopus)

Glycan profiling of gestational choriocarcinoma using a lectin microarray

Kobayashi, Y., Masuda, K., Banno, K., Kobayashi, N., Umene, K., Nogami, Y., Tsuji, K., Ueki, A., Nomura, H., Sato, K., Tominaga, E., Shimizu, T., Saya, H. & Aoki, D., 2014 3, : : Oncology Reports. 31, 3, p. 1121-1126 6 p.

研究成果: Article

Choriocarcinoma
Lectins
Polysaccharides
Carcinogenesis
Placental Site Trophoblastic Tumor
74 引用 (Scopus)
MicroRNAs
tumor
Uterine Cervical Neoplasms
Tumors
cancer
2013
6 引用 (Scopus)
Choriocarcinoma
Transcriptome
Placenta
Cell Line
Carcinogenesis
1 引用 (Scopus)

HMMC-1, a human monoclonal antibody to fucosylated core 1 O-glycan, suppresses growth of uterine endometrial cancer cells

Oikawa, F., Kojima-Aikawa, K., Inoue, F., Suzuki, A., Tanaka, K., Tominaga, E. & Aoki, D., 2013 1, : : Cancer Science. 104, 1, p. 62-69 8 p.

研究成果: Article

Uterine Neoplasms
Endometrial Neoplasms
Polysaccharides
Monoclonal Antibodies
Epitopes
19 引用 (Scopus)

New candidate therapeutic agents for endometrial cancer: Potential for clinical practice (Review)

Umene, K., Banno, K., Kisu, I., Yanokura, M., Nogami, Y., Tsuji, K., Masuda, K., Ueki, A., Kobayashi, Y., Yamagami, W., Tominaga, E., Susumu, N. & Aoki, D., 2013 3, : : Oncology Reports. 29, 3, p. 855-860 6 p.

研究成果: Article

Endometrial Neoplasms
G1 Phase Cell Cycle Checkpoints
Combined Modality Therapy
Neoplasms
Growth Inhibitors
13 引用 (Scopus)

Polymorphisms in the UGT1A1 gene predict adverse effects of irinotecan in the treatment of gynecologic cancer in Japanese patients

Hirasawa, A., Zama, T., Akahane, T., Nomura, H., Kataoka, F., Saito, K., Okubo, K., Tominaga, E., Makita, K., Susumu, N., Kosaki, K., Tanigawara, Y. & Aoki, D., 2013 12, : : Journal of Human Genetics. 58, 12, p. 794-798 5 p.

研究成果: Article

irinotecan
Glucuronosyltransferase
Uridine Diphosphate
Genes
Neoplasms
12 引用 (Scopus)

The origin of stroma surrounding epithelial ovarian cancer cells

Akahane, T., Hirasawa, A., Tsuda, H., Kataoka, F., Nishimura, S., Tanaka, H., Tominaga, E., Nomura, H., Chiyoda, T., Iguchi, Y., Yamagami, W., Susumu, N. & Aoki, D., 2013 1, : : International Journal of Gynecological Pathology. 32, 1, p. 26-30 5 p.

研究成果: Article

Neoplasms
Ovarian epithelial cancer
Mutation
Bone Marrow
Epithelial-Mesenchymal Transition
2012
13 引用 (Scopus)
irinotecan
Gene Silencing
Epigenomics
Uterine Cervical Neoplasms
decitabine
23 引用 (Scopus)

Biomarkers in endometrial cancer: Possible clinical applications (review)

Banno, K., Kisu, I., Yanokura, M., Tsuji, K., Masuda, K., Ueki, A., Kobayashi, Y., Yamagami, W., Nomura, H., Tominaga, E., Susumu, N. & Aoki, D., 2012 6, : : Oncology Letters. 3, 6, p. 1175-1180 6 p.

研究成果: Article

Endometrial Neoplasms
Biomarkers
Genes
DNA Mismatch Repair
Ploidies
2 引用 (Scopus)

Cervical cancer screening

Aoki, D., Saito, E. & Tominaga, E., 2012 1 15, : : Japanese Journal of Cancer and Chemotherapy. 39, 1, p. 23-26 4 p.

研究成果: Article

Early Detection of Cancer
Uterine Cervical Neoplasms
Cell Biology
Japan
Cervical Intraepithelial Neoplasia
27 引用 (Scopus)

Epimutation and cancer: A new carcinogenic mechanism of Lynch syndrome (Review)

Banno, K., Kisu, I., Yanokura, M., Tsuji, K., Masuda, K., Ueki, A., Kobayashi, Y., Yamagami, W., Nomura, H., Tominaga, E., Susumu, N. & Aoki, D., 2012 9, : : International Journal of Oncology. 41, 3, p. 793-797 5 p.

研究成果: Article

Hereditary Nonpolyposis Colorectal Neoplasms
Epigenetic Repression
Colorectal Neoplasms
Neoplasms
Carcinogenesis
27 引用 (Scopus)

Objective evaluation of the alleviating effects of Goshajinkigan on peripheral neuropathy induced by paclitaxel/carboplatin therapy: A multicenter collaborative study

Kaku, H., Kumagai, S., Onoue, H., Takada, A., Shoji, T., Miura, F., Yoshizaki, A., Sato, S., Kigawa, J., Arai, T., Tsunoda, S., Tominaga, E., Aoki, D. & Sugiyama, T., 2012 1, : : Experimental and Therapeutic Medicine. 3, 1, p. 60-65 6 p.

研究成果: Article

Carboplatin
Peripheral Nervous System Diseases
Paclitaxel
Multicenter Studies
Therapeutics
12 引用 (Scopus)

Relationship of lower uterine segment cancer with Lynch syndrome: A novel case with an hMLH1 germline mutation

Masuda, K., Banno, K., Hirasawa, A., Yanokura, M., Tsuji, K., Kobayashi, Y., Kisu, I., Ueki, A., Nomura, H., Tominaga, E., Susumu, N. & Aoki, D., 2012 11, : : Oncology Reports. 28, 5, p. 1537-1543 7 p.

研究成果: Article

Hereditary Nonpolyposis Colorectal Neoplasms
Uterine Neoplasms
Germ-Line Mutation
Endometrial Neoplasms
Microsatellite Instability
2 引用 (Scopus)
irinotecan
Platinum
Retrospective Studies
Therapeutics
Hand-Foot Syndrome
2011

The chemosensitivity of nodal metastases in recurrent epithelial ovarian cancer

Kataoka, F., Tsuda, H., Nomura, H., Chiyoda, T., Tominaga, E., Suzuki, A., Susumu, N. & Aoki, D., 2011, : : European Journal of Gynaecological Oncology. 32, 2, p. 160-163 4 p.

研究成果: Article

Neoplasm Metastasis
Drug Therapy
Lymph Nodes
Abdominal Cavity
Ovarian Neoplasms
2010
14 引用 (Scopus)

Amplification of GNAS may be an independent, qualitative, and reproducible biomarker to predict progression-free survival in epithelial ovarian cancer

Tominaga, E., Tsuda, H., Arao, T., Nishimura, S., Takano, M., Kataoka, F., Nomura, H., Hirasawa, A., Aoki, D. & Nishio, K., 2010 8 1, : : Gynecologic Oncology. 118, 2, p. 160-166 7 p.

研究成果: Article

Disease-Free Survival
Biomarkers
Genes
Microarray Analysis
Chromosomes, Human, Pair 20
8 引用 (Scopus)
Platinum
Ovarian Neoplasms
Drug Therapy
Survival
taxane
32 引用 (Scopus)

Lymph node metastasis in grossly apparent stages I and II epithelial ovarian cancer

Nomura, H., Tsuda, H., Susumu, N., Fujii, T., Banno, K., Kataoka, F., Tominaga, E., Suzuki, A., Chiyoda, T. & Aoki, D., 2010 4, : : International Journal of Gynecological Cancer. 20, 3, p. 341-345 5 p.

研究成果: Article

Lymph Nodes
Neoplasm Metastasis
Lymph Node Excision
Ovarian epithelial cancer
Incidence
1999
100 引用 (Scopus)

Prognosis of Japanese patients with ovarian clear cell carcinoma associated with pelvic endometriosis: Clinicopathologic evaluation

Komiyama, S. I., Aoki, D., Tominaga, E., Susumu, N., Udagawa, Y. & Nozawa, S., 1999 3, : : Gynecologic Oncology. 72, 3, p. 342-346 5 p.

研究成果: Article

Endometriosis
Carcinoma
Survival Rate
Cell Biology
Incidence

Two soluble forms of β1,4-galactosyltransferase released from ovarian cancer cells and from COS-1 cells transfected with its cDNA

Aoki, D., Saitoh, E., Matsumoto, Y., Tominaga, E., Hirasawa, A., Susumu, N., Udagawa, Y. & Nozawa, S., 1999, : : Acta Histochemica et Cytochemica. 32, 3, p. 209-214 6 p.

研究成果: Article

Galactosyltransferases
COS Cells
Ovarian Neoplasms
Complementary DNA
Cells