嶋 晴子

研究成果

年別の研究成果 2005 2010 2017 2018 2019 2022 2022

• 25 Article
• 5 Letter

年別の研究成果

年別の研究成果

検索結果

• 2022

  Cervical Edema Extending to the Larynx as Local Cytokine Release Syndrome Following Chimeric Antigen Receptor T-Cell Therapy in a Boy with Refractory Acute Lymphoblastic Leukemia

  Shima, H., Kurosawa, T., Oikawa, H., Kobayashi, H., Nishi, E., Yamazaki, F., Tomita, K. & Shimada, H., 2022 3月 15, In: Case Reports in Oncology. 15, 1, p. 257-262 6 p.

  研究成果: Article › 査読

  Open Access

  • Cytokine Release Syndrome 100%
  • Chimeric Antigen Receptors 83%
  • Larynx 65%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 60%
  • Cell- and Tissue-Based Therapy 58%

• Discontinuation of tyrosine kinase inhibitors in pediatric chronic myeloid leukemia

  Shima, H., Kada, A., Tanizawa, A., Sato, I., Tono, C., Ito, M., Yuza, Y., Watanabe, A., Kamibeppu, K., Uryu, H., Koh, K., Imai, C., Yoshida, N., Koga, Y., Fujita, N., Saito, A. M., Adachi, S., Ishii, E. & Shimada, H., 2022 8月, In: Pediatric Blood and Cancer. 69, 8, e29699.

  研究成果: Article › 査読

  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 100%
  • Protein-Tyrosine Kinases 86%
  • Pediatrics 61%
  • Leukemia, Myeloid, Chronic Phase 10%
  • Academic Performance 10%
  3 被引用数 (Scopus)

• Potential benefits of rapid genetic testing for germline WT1 in infants with bilateral renal tumors: A case report

  Yoshikawa, H., Sato, T., Ishikawa, T., Ito, J., Yamazaki, F., Shima, H., Honda, M., Shibata, H., Ishii, T., Asanuma, H., Shimada, H. & Hasegawa, T., 2022 2月, In: Pediatric Blood and Cancer. 69, 2, e29368.

  研究成果: Letter › 査読
• 2021

  A case of primary CNS embryonal rhabdomyosarcoma with PAX3-NCOA2 fusion and systematic meta-review

  Tanaka, R., Inoue, K., Yamada, Y., Yoshida, M., Shima, H., Ito, J., Okita, H., Miwa, T., Kato, M. & Shimada, H., 2021 9月, In: Journal of Neuro-Oncology. 154, 2, p. 247-256 10 p.

  研究成果: Article › 査読

  • Embryonal Rhabdomyosarcoma 100%
  • Rhabdomyosarcoma 81%
  • Central Nervous System 50%
  • Systematic Reviews 50%
  • Demography 12%
  1 被引用数 (Scopus)
• 2020

  A Case of Pulmonary Veno-occlusive Disease following Hepatic Veno-occlusive Disease after Autologous Hematopoietic Stem Cell Transplantation for Neuroblastoma

  Isshiki, K., Shima, H., Yamazaki, F., Takenouchi, T. & Shimada, H., 2020 10月 1, In: Journal of Pediatric Hematology/Oncology. 42, 7, p. e677-e679

  研究成果: Article › 査読

  • Pulmonary Veno-Occlusive Disease 100%
  • Hepatic Veno-Occlusive Disease 91%
  • Hematopoietic Stem Cell Transplantation 63%
  • Neuroblastoma 59%
  • Conservative Treatment 26%
  1 被引用数 (Scopus)

• Central nervous system ganglioneuroblastoma harboring MYO5A-NTRK3 fusion

  Ito, J., Nakano, Y., Shima, H., Miwa, T., Kogure, Y., Isshiki, K., Yamazaki, F., Oishi, Y., Morimoto, Y., Kataoka, K., Okita, H., Hirato, J., Ichimura, K. & Shimada, H., 2020 7月 1, In: Brain tumor pathology. 37, 3, p. 105-110 6 p.

  研究成果: Article › 査読

  • Ganglioneuroblastoma 100%
  • Central Nervous System 46%
  • Radiotherapy 26%
  • Neoplasms 20%
  • Supratentorial Neoplasms 19%
  1 被引用数 (Scopus)
• 2019

  Generalized eruptive histiocytoma developing into xanthoma disseminatum with central diabetes insipidus

  Kobayashi, K., Kurihara, Y., Yamagami, J., Ito, J., Shima, H., Shimada, H., Ichimura, C., Ishiko, A., Amagai, M. & Ouchi, T., 2019 1月 1, In: Journal of Dermatology.

  研究成果: Letter › 査読
  2 被引用数 (Scopus)

• Haploidentical stem cell transplantation with posttransplant cyclophosphamide for refractory systemic juvenile xanthogranuloma

  Ito, J., Shima, H., Inoue, K., Yamazaki, F. & Shimada, H., 2019, In: Pediatric Blood and Cancer. 66, 10, e27926.

  研究成果: Article › 査読

  • Juvenile Xanthogranuloma 100%
  • Non-Langerhans-Cell Histiocytosis 67%
  • Hematopoietic Stem Cell Transplantation 66%
  • Stem Cell Transplantation 65%
  • Cyclophosphamide 58%
  4 被引用数 (Scopus)

• Living donor liver re-transplantation for recurrent hepatoblastoma in the liver graft following complete eradication of peritoneal metastases under indocyanine green fluorescence imaging

  Takahashi, N., Yamada, Y., Hoshino, K., Kawaida, M., Mori, T., Abe, K., Fujimura, T., Matsubara, K., Hibi, T., Shinoda, M., Obara, H., Isshiki, K., Shima, H., Shimada, H., Kameyama, K., Fuchimoto, Y., Kitagawa, Y. & Kuroda, T., 2019 5月, In: Cancers. 11, 5, 730.

  研究成果: Article › 査読

  Open Access

  • Hepatoblastoma 100%
  • Indocyanine Green 86%
  • Living Donors 82%
  • Optical Imaging 80%
  • Liver Transplantation 66%
  21 被引用数 (Scopus)

• Testicular involvement without testicular enlargement in a young male with atypical chronic myeloid leukemia

  Shima, H., Ito, J., Isshiki, K., Sekinaka, Y., Yamazaki, F. & Shimada, H., 2019, In: Pediatric Blood and Cancer. 66, 10, e27911.

  研究成果: Letter › 査読
• 2018

  High-dose chemotherapy without whole lung radiation for refractory pulmonary metastases in an infant with stage IV favorable histology Wilms tumor

  Shima, H., Yamada, Y., Asanuma, H. & Shimada, H., 2018 1月 1, (Accepted/In press) In: Pediatric Blood and Cancer.

  研究成果: Article › 査読

• Nodular lymphocyte-predominant hodgkin lymphoma in a 15-year-old boy with li-fraumeni syndrome having a germline TP53 D49H mutation

  Yamazaki, F., Shima, H., Osumi, T., Narumi, S., Kuroda, T. & Shimada, H., 2018, In: Journal of Pediatric Hematology/Oncology. 40, 3, p. e195-e197

  研究成果: Article › 査読

  • Li-Fraumeni Syndrome 100%
  • Hodgkin Disease 66%
  • Germ-Line Mutation 48%
  • Siblings 39%
  • Mutation 36%
  3 被引用数 (Scopus)

• Rationale and design of a prospective, multicentre, stop tyrosine kinase inhibitor trial of paediatric patients with chronic myeloid Leukaemia with sustained complete molecular response (STKI-14)

  Kada, A., Shima, H., Tono, C., Yuza, Y., Kurosawa, H., Watanabe, A., Ito, M., Uryu, H., Kamibeppu, K., Kiyokawa, N., Adachi, S., Saito, A. M., Tanizawa, A. & Shimada, H., 2018 3月, In: Hiroshima Journal of Medical Sciences. 67, 1, p. 7-13 7 p.

  研究成果: Article › 査読

  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 100%
  • Protein-Tyrosine Kinases 86%
  • Pediatrics 61%
  • Myeloid Progenitor Cells 18%
  • Child 17%
  1 被引用数 (Scopus)

• Ring1A and Ring1B inhibit expression of Glis2 to maintain murine MOZ-TIF2 AML stem cells

  Shima, H., Takamatsu-Ichihara, E., Shino, M., Yamagata, K., Katsumoto, T., Aikawa, Y., Fujita, S., Koseki, H. & Kitabayashi, I., 2018 4月 19, In: Blood. 131, 16, p. 1833-1845 13 p.

  研究成果: Article › 査読

  Open Access

  • Acute Myeloid Leukemia 100%
  • Stem Cells 77%
  • Polycomb Repressive Complex 1 25%
  • Cell Self Renewal 18%
  • Neoplastic Stem Cells 15%
  10 被引用数 (Scopus)

• Sequential use of second-generation tyrosine kinase inhibitors following imatinib therapy in pediatric chronic myeloid leukemia: A report from the Japanese Pediatric Leukemia/Lymphoma Study Group

  Kurosawa, H., Tanizawa, A., Muramatsu, H., Tono, C., Watanabe, A., Shima, H., Ito, M., Yuza, Y., Hamamoto, K., Hotta, N., Okada, M., Saito, A. M., Manabe, A., Mizutani, S., Adachi, S., Horibe, K., Ishii, E. & Shimada, H., 2018 12月, In: Pediatric Blood and Cancer. 65, 12, e27368.

  研究成果: Article › 査読

  • Imatinib Mesylate 100%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 92%
  • Protein-Tyrosine Kinases 80%
  • Lymphoma 73%
  • 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide 72%
  8 被引用数 (Scopus)
• 2017

  Flow cytometric analysis as an additional predictive tool of treatment response in children with chronic-phase chronic myeloid leukemia treated with imatinib

  Shima, H., Kiyokawa, N., Miharu, M., Tanizawa, A., Kurosawa, H., Watanabe, A., Ito, M., Tono, C., Yuza, Y., Muramatsu, H., Hotta, N., Okada, M., Hamamoto, K., Kajiwara, R., Saito, A. M., Horibe, K., Mizutani, S., Adachi, S., Ishii, E. & Shimada, H., 2017 9月, In: Pediatric Blood and Cancer. 64, 9, e26478.

  研究成果: Article › 査読

  • Leukemia, Myeloid, Chronic Phase 100%
  • Imatinib Mesylate 83%
  • Bone Marrow 53%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 51%
  • Child 31%
  1 被引用数 (Scopus)

• Severe hypertriglyceridemia during treatment of acute lymphoblastic leukemia associated with type III hyperlipoproteinemia

  Yamada, Y., Shima, H., Shibata, H., Ishii, T., Hasegawa, T. & Shimada, H., 2017, (Accepted/In press) In: Pediatric Blood and Cancer.

  研究成果: Article › 査読

• Successful haploidentical BMT with post-transplant cyclophosphamide for refractory autoimmune pancytopenia after cord blood transplant in pediatric myelodysplastic syndrome

  Shima, H., Isshiki, K., Yamada, Y., Yamazaki, F., Takahashi, T. & Shimada, H., 2017 4月 1, In: Bone Marrow Transplantation. 52, 4, p. 653-655 3 p.

  研究成果: Letter › 査読

  Open Access
  1 被引用数 (Scopus)
• 2016

  Leukostasis in Children and Adolescents with Chronic Myeloid Leukemia: Japanese Pediatric Leukemia/Lymphoma Study Group

  Kurosawa, H., Tanizawa, A., Tono, C., Watanabe, A., Shima, H., Ito, M., Yuza, Y., Hotta, N., Muramatsu, H., Okada, M., Kajiwara, R., Moriya Saito, A., Mizutani, S., Adachi, S., Horibe, K., Ishii, E. & Shimada, H., 2016 3月 1, In: Pediatric Blood and Cancer. 63, 3, p. 406-411 6 p.

  研究成果: Article › 査読

  • Leukostasis 100%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 64%
  • Lymphoma 51%
  • Leukemia 50%
  • Pediatrics 39%
  16 被引用数 (Scopus)
• 2014

  Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion

  Shima, H., Yamagata, K., Aikawa, Y., Shino, M., Koseki, H., Shimada, H. & Kitabayashi, I., 2014 1月, In: International journal of hematology. 99, 1, p. 21-31 11 p.

  研究成果: Article › 査読

  • PHD Zinc Fingers 100%
  • Acute Myeloid Leukemia 39%
  • Leukemia 25%
  • Proteins 22%
  • Acetylation 21%
  23 被引用数 (Scopus)
• 2011

  Distinct impact of imatinib on growth at prepubertal and pubertal ages of children with chronic myeloid leukemia

  Shima, H., Tokuyama, M., Tanizawa, A., Tono, C., Hamamoto, K., Muramatsu, H., Watanabe, A., Hotta, N., Ito, M., Kurosawa, H., Kato, K., Tsurusawa, M., Horibe, K. & Shimada, H., 2011 10月, In: Journal of Pediatrics. 159, 4, p. 676-681 6 p.

  研究成果: Article › 査読

  • Imatinib Mesylate 100%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 92%
  • Growth 44%
  • Child 38%
  • Puberty 20%
  92 被引用数 (Scopus)
• 2010

  Acquisition of G₀ state by CD34-positive cord blood cells after bone marrow transplantation

  Shima, H., Takubo, K., Tago, N., Iwasaki, H., Arai, F., Takahashi, T. & Suda, T., 2010 12月, In: Experimental Hematology. 38, 12, p. 1231-1240 10 p.

  研究成果: Article › 査読

  • Bone Marrow Transplantation 100%
  • Hematopoietic Stem Cells 96%
  • Fetal Blood 96%
  • Blood Cells 80%
  • Cell Cycle 38%
  25 被引用数 (Scopus)

• Differences in voriconazole trough plasma concentrations per oral dosages between children younger and older than 3 years of age

  Shima, H., Miharu, M., Osumi, T., Takahashi, T. & Shimada, H., 2010 7月 1, In: Pediatric Blood and Cancer. 54, 7, p. 1050-1052 3 p.

  研究成果: Article › 査読

  • Voriconazole 100%
  • Child 34%
  • Poisons 11%
  • Therapeutics 2%
  44 被引用数 (Scopus)

• Protein-losing enteropathy caused by gastrointestinal tract-involved Langerhans cell histiocytosis

  Shima, H., Takahashi, T. & Shimada, H., 2010 2月, In: Pediatrics. 125, 2, p. e426-e432

  研究成果: Article › 査読

  • Protein-Losing Enteropathies 100%
  • Langerhans Cell Histiocytosis 87%
  • Gastrointestinal Tract 58%
  • Hemophagocytic Lymphohistiocytosis 29%
  • Disseminated Intravascular Coagulation 13%
  23 被引用数 (Scopus)

• PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2

  Aikawa, Y., Katsumoto, T., Zhang, P., Shima, H., Shino, M., Terui, K., Ito, E., Ohno, H., Stanley, E. R., Singh, H., Tenen, D. G. & Kitabayashi, I., 2010 5月, In: Nature medicine. 16, 5, p. 580-585 6 p.

  研究成果: Article › 査読

  • Ablation 100%
  • Leukemia 70%
  • Colony Stimulating Factor 64%
  • Stem Cells 63%
  • Up-Regulation 62%
  74 被引用数 (Scopus)

• Regulation of the HIF-1α level is essential for hematopoietic stem cells

  Takubo, K., Goda, N., Yamada, W., Iriuchishima, H., Ikeda, E., Kubota, Y., Shima, H., Johnson, R. S., Hirao, A., Suematsu, M. & Suda, T., 2010 9月 3, In: Cell stem cell. 7, 3, p. 391-402 12 p.

  研究成果: Article › 査読

  • Hypoxia-Inducible Factor 1 100%
  • Hematopoietic Stem Cells 78%
  • Cell Cycle 35%
  • Bone Marrow Transplantation 23%
  • Bone Marrow 16%
  667 被引用数 (Scopus)
• 2009

  A case of multisystem Langerhans cell histiocytosis with primary hypothyroidism followed by type 1 diabetes mellitus

  Shima, H., Inokuchi, M. & Shimada, H., 2009 8月, In: Pediatric Blood and Cancer. 53, 2, p. 232-234 3 p.

  研究成果: Article › 査読

  • Langerhans Cell Histiocytosis 100%
  • Hypothyroidism 78%
  • Type 1 Diabetes Mellitus 68%
  • Thyroid Gland 31%
  • Diabetes Mellitus 30%
  8 被引用数 (Scopus)

• Reconstitution activity of hypoxic cultured human cord blood CD34-positive cells in NOG mice

  Shima, H., Takubo, K., Iwasaki, H., Yoshihara, H., Gomei, Y., Hosokawa, K., Arai, F., Takahashi, T. & Suda, T., 2009 1月 16, In: Biochemical and Biophysical Research Communications. 378, 3, p. 467-472 6 p.

  研究成果: Article › 査読

  • Cord 100%
  • Hematopoietic Stem Cells 80%
  • Fetal Blood 80%
  • Hypoxia 38%
  • Bone Marrow 23%
  40 被引用数 (Scopus)
• 2007

  Function of oxidative stress in the regulation of hematopoietic stem cell-niche interaction

  Hosokawa, K., Arai, F., Yoshihara, H., Nakamura, Y., Gomei, Y., Iwasaki, H., Miyamoto, K., Shima, H., Ito, K. & Suda, T., 2007 11月 23, In: Biochemical and Biophysical Research Communications. 363, 3, p. 578-583 6 p.

  研究成果: Article › 査読

  • Stem Cell Niche 100%
  • Oxidative Stress 76%
  • Hematopoietic Stem Cells 76%
  • Cell Communication 72%
  • Reactive Oxygen Metabolite 72%
  96 被引用数 (Scopus)
• 2005

  Little response to zoledronic acid in a child of juvenile myelomonocytic leukemia (JMML) harboring the PTPN11 mutation [2]

  Shimada, H., Shima, H., Shimasaki, N., Yoshihara, H., Mori, T. & Takahashi, T., 2005 8月, In: Annals of Oncology. 16, 8, p. 1400 1 p.

  研究成果: Letter › 査読
  11 被引用数 (Scopus)