三澤 日出巳

研究成果

年別の研究成果 1987 1994 1995 1997 2004 2007 2008 2012 2016 2017 2018 2020 2022

• 5424 被引用数
• 41 h-index
• 103 Article
• 5 Review article
• 1 Conference contribution
• 1 Comment/debate

年別の研究成果

年別の研究成果

検索結果

• 2007

  Diminished antigen-specific IgG₁ and interleukin-6 production and acetylcholinesterase expression in combined M₁ and M₅ muscarinic acetylcholine receptor knockout mice

  Fujii, Y. X., Tashiro, A., Arimoto, K., Fujigaya, H., Moriwaki, Y., Misawa, H., Fujii, T., Matsui, M., Kasahara, T. & Kawashima, K., 2007 8月, In: Journal of Neuroimmunology. 188, 1-2, p. 80-85 6 p.

  研究成果: Article › 査読

  • Acetylcholinesterase 100%
  • Muscarinic Receptors 98%
  • Knockout Mice 82%
  • Ovalbumin 75%
  • Interleukin-6 69%
  39 被引用数 (Scopus)

• Enhanced serum antigen-specific IgG₁ and proinflammatory cytokine production in nicotinic acetylcholine receptor α7 subunit gene knockout mice

  Fujii, Y. X., Fujigaya, H., Moriwaki, Y., Misawa, H., Kasahara, T., Grando, S. A. & Kawashima, K., 2007 9月, In: Journal of Neuroimmunology. 189, 1-2, p. 69-74 6 p.

  研究成果: Article › 査読

  • Gene Knockout Techniques 100%
  • Nicotinic Receptors 90%
  • Knockout Mice 75%
  • Immunoglobulin G 62%
  • Antigens 52%
  69 被引用数 (Scopus)

• Expression and function of genes encoding cholinergic components in murine immune cells

  Kawashima, K., Yoshikawa, K., Fujii, Y. X., Moriwaki, Y. & Misawa, H., 2007 5月 30, In: Life Sciences. 80, 24-25, p. 2314-2319 6 p.

  研究成果: Article › 査読

  • Cholinergic 100%
  • Mononuclear Leukocytes 80%
  • Cholinergic Agents 73%
  • Dendritic Cells 70%
  • Acetylcholine 62%
  163 被引用数 (Scopus)

• Immune system expression of SLURP-1 and SLURP-2, two endogenous nicotinic acetylcholine receptor ligands

  Moriwaki, Y., Yoshikawa, K., Fukuda, H., Fujii, Y. X., Misawa, H. & Kawashima, K., 2007 5月 30, In: Life Sciences. 80, 24-25, p. 2365-2368 4 p.

  研究成果: Article › 査読

  • Nicotinic Receptors 100%
  • Acetylcholine 96%
  • Immune System 71%
  • Ligands 64%
  • Messenger RNA 51%
  71 被引用数 (Scopus)

• Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice

  Olsen, O., Funke, L., Long, J. F., Fukata, M., Kazuta, T., Trinidad, J. C., Moore, K. A., Misawa, H., Welling, P. A., Burlingame, A. L., Zhang, M. & Bredt, D. S., 2007 10月 8, In: Journal of Cell Biology. 179, 1, p. 151-164 14 p.

  研究成果: Article › 査読

  • Knockout Mice 100%
  • Epithelium 59%
  • Kidney 58%
  • Cystic Kidney Diseases 43%
  • Cell Polarity 19%
  36 被引用数 (Scopus)

• Ubiquitous expression of acetylcholine and its biological functions in life forms without nervous systems

  Kawashima, K., Misawa, H., Moriwaki, Y., Fujii, Y. X., Fujii, T., Horiuchi, Y., Yamada, T., Imanaka, T. & Kamekura, M., 2007 5月 30, In: Life Sciences. 80, 24-25, p. 2206-2209 4 p.

  研究成果: Article › 査読

  • Acetylcholine 100%
  • Nervous System 76%
  • Shiitake Mushrooms 38%
  • Choline 33%
  • Choline O-Acetyltransferase 28%
  72 被引用数 (Scopus)
• 2006

  Conditional knockout of Mn superoxide dismutase in postnatal motor neurons reveals resistance to mitochondrial generated superoxide radicals

  Misawa, H., Nakata, K., Matsuura, J., Moriwaki, Y., Kawashima, K., Shimizu, T., Shirasawa, T. & Takahashi, R., 2006 7月, In: Neurobiology of Disease. 23, 1, p. 169-177 9 p.

  研究成果: Article › 査読

  • Superoxides 100%
  • Motor Neurons 96%
  • Superoxide Dismutase 91%
  • Axons 58%
  • Neurons 40%
  42 被引用数 (Scopus)
• 2005

  Neurotransmitter release regulated by a MALS-liprin-α presynaptic complex

  Olsen, O., Moore, K. A., Fukata, M., Kazuta, T., Trinidad, J. C., Kauer, F. W., Streuli, M., Misawa, H., Burlingame, A. L., Nicoll, R. A. & Bredt, D. S., 2005 9月 26, In: Journal of Cell Biology. 170, 7, p. 1127-1134 8 p.

  研究成果: Article › 査読

  • Neurotransmitter Agents 100%
  • Adhesives 53%
  • Synapses 52%
  • Mentha 43%
  • Proteins 42%
  100 被引用数 (Scopus)
• 2004

  Calcium-permeable AMPA receptors promote misfolding of mutant SOD1 protein and development of amyotrophic lateral sclerosis in a transgenic mouse model

  Tateno, M., Sadakata, H., Tanaka, M., Itohara, S., Shin, R. M., Miura, M., Masuda, M., Aosaki, T., Urushitani, M., Misawa, H. & Takahashi, R., 2004 10月 1, In: Human molecular genetics. 13, 19, p. 2183-2196 14 p.

  研究成果: Article › 査読

  • Superoxide Dismutase-1 100%
  • AMPA Receptors 93%
  • Amyotrophic Lateral Sclerosis 84%
  • Mutant Proteins 84%
  • Transgenic Mice 70%
  125 被引用数 (Scopus)

• Comparative study of gene expression of cholinergic system-related molecules in the human spinal cord and term placenta

  Oda, Y., Muroishi, Y., Misawa, H. & Suzuki, S., 2004, In: Neuroscience. 128, 1, p. 39-49 11 p.

  研究成果: Article › 査読

  • Transcriptional Silencer Elements 100%
  • Choline O-Acetyltransferase 93%
  • Vesicular Acetylcholine Transport Proteins 85%
  • RE1-silencing transcription factor 73%
  • Cholinergic Agents 71%
  19 被引用数 (Scopus)

• c-Ret regulates cholinergic properties in mouse sympathetic neurons: From mutant mice

  Burau, K., Stenull, I., Huber, K., Misawa, H., Berse, B., Unsicker, K. & Ernsberger, U., 2004 7月, In: European Journal of Neuroscience. 20, 2, p. 353-362 10 p.

  研究成果: Article › 査読

  • Vesicular Acetylcholine Transport Proteins 100%
  • Choline O-Acetyltransferase 78%
  • Cholinergic Agents 59%
  • Neurons 39%
  • Cholinergic Neurons 39%
  40 被引用数 (Scopus)

• Novel analogs of choline as potential neuroprotective agents

  Buccafusco, J. J., Beach, J. W., Terry, A. V., Doad, G. S., Sood, A., Arias, E., Misawa, H., Masai, M., Fujii, T. & Kawashima, K., 2004 1月 1, In: Journal of Alzheimer's Disease. 6, SUPPL., p. S85-S92

  研究成果: Article › 査読

  • Choline 100%
  • PC 96%
  • Neuroprotective Agents 95%
  • withdrawal 89%
  • nicotine 88%
  8 被引用数 (Scopus)

• The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons

  Mori, T., Yuxing, Z., Takaki, H., Takeuchi, M., Iseki, K., Hagino, S., Kitanaka, J. I., Takemura, M., Misawa, H., Ikawa, M., Okabe, M. & Wanaka, A., 2004 6月 1, In: European Journal of Neuroscience. 19, 12, p. 3129-3141 13 p.

  研究成果: Article › 査読

  • Basal Forebrain 100%
  • Cholinergic Neurons 96%
  • Homeobox Genes 92%
  • Vesicular Acetylcholine Transport Proteins 20%
  • Nerve Growth Factor Receptor 17%
  82 被引用数 (Scopus)

• Ultrastructural localization of high-affinity choline transporter in the rat neuromuscular junction: Enrichment on synaptic vesicles

  Nakata, K., Okuda, T. & Misawa, H., 2004 7月, In: Synapse. 53, 1, p. 53-56 4 p.

  研究成果: Article › 査読

  • choline transporter 100%
  • Neuromuscular Junction 70%
  • Synaptic Vesicles 70%
  • Choline 64%
  • Cell Membrane 43%
  46 被引用数 (Scopus)
• 2003

  Hyperproliferation of synapses on spinal motor neurons of Duchenne muscular dystrophy and myotonic dystrophy patients

  Nagao, M., Kato, S., Hayashi, H. & Misawa, H., 2003 12月, In: Acta Neuropathologica. 106, 6, p. 557-560 4 p.

  研究成果: Article › 査読

  • Myotonic Dystrophy 100%
  • Duchenne Muscular Dystrophy 91%
  • Motor Neurons 75%
  • Synapses 71%
  • Vesicular Acetylcholine Transport Proteins 30%
  4 被引用数 (Scopus)

• The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model

  Inoue, H., Tsukita, K., Iwasato, T., Suzuki, Y., Tomioka, M., Tateno, M., Nagao, M., Kawata, A., Saido, T. C., Miura, M., Misawa, H., Itohara, S. & Takahashi, R., 2003 12月 15, In: EMBO Journal. 22, 24, p. 6665-6674 10 p.

  研究成果: Article › 査読

  • Apoptotic 100%
  • Caspase 9 98%
  • Amyotrophic Lateral Sclerosis 93%
  • Superoxide 84%
  • Disease Progression 69%
  94 被引用数 (Scopus)

• VAChT-Cre.Fast and VAChT-Cre.Slow: Postnatal expression of Cre recombinase in somatomotor neurons with different onset

  Misawa, H., Nakata, K., Toda, K., Matsuura, J., Oda, Y., Inoue, H., Tateno, M. & Takahashi, R., 2003 9月 1, In: Genesis. 37, 1, p. 44-50 7 p.

  研究成果: Article › 査読

  • Vesicular Acetylcholine Transport Proteins 100%
  • Cre recombinase 86%
  • Neurons 39%
  • Cholinergic Agents 22%
  • Cholinergic Neurons 19%
  27 被引用数 (Scopus)
• 2002

  Identification of a monogenic locus (jams1) causing juvenile audiogenic seizures in mice

  Misawa, H., Sherr, E. H., Lee, D. J., Chetkovich, D. M., Tan, A., Schreiner, C. E. & Bredt, D. S., 2002 12月 1, In: Journal of Neuroscience. 22, 23, p. 10088-10093 6 p.

  研究成果: Article › 査読

  Open Access

  • Seizures 100%
  • Epileptic Syndromes 47%
  • Epilepsy 46%
  • Organism Cloning 33%
  • Genes 29%
  23 被引用数 (Scopus)
• 2001

  Cellular mRNA expression of the transcription factor NGFI-B suggests a gene regulatory role in striatal opiate-peptide neurons

  Bäckman, C., Hoffer, B. J., Misawa, H. & Morales, M., 2001 6月 8, In: Brain Research. 903, 1-2, p. 26-32 7 p.

  研究成果: Article › 査読

  • Opioid Peptides 100%
  • Regulator Genes 83%
  • Corpus Striatum 78%
  • Transcription Factors 60%
  • Neurons 49%
  7 被引用数 (Scopus)

• Contrasting Localizations of MALS/LIN-7 PDZ Proteins in Brain and Molecular Compensation in Knockout Mice

  Misawa, H., Kawasaki, Y., Mellor, J., Sweeney, N., Jo, K., Nicoll, R. A. & Bredt, D. S., 2001 3月 23, In: Journal of Biological Chemistry. 276, 12, p. 9264-9272 9 p.

  研究成果: Article › 査読

  • Knockout Mice 100%
  • Brain 53%
  • Protein 45%
  • Proteins 40%
  • Post-Synaptic Density 16%
  43 被引用数 (Scopus)

• Distribution of the high-affinity choline transporter in the central nervous system of the rat

  Misawa, H., Nakata, K., Matsuura, J., Nagao, M., Okuda, T. & Haga, T., 2001 7月 16, In: Neuroscience. 105, 1, p. 87-98 12 p.

  研究成果: Article › 査読

  • choline transporter 100%
  • Central Nervous System 44%
  • Cholinergic Neurons 24%
  • Presynaptic Terminals 22%
  • Antibodies 22%
  88 被引用数 (Scopus)
• 2000

  Aberrant splicing of human Cu/Zn superoxide dismutase (SOD1) RNA transcripts

  Kawata, A., Kato, S., Shimizu, T., Hayashi, H., Hirai, S., Misawa, H. & Takahashi, R., 2000 8月 21, In: NeuroReport. 11, 12, p. 2649-2653 5 p.

  研究成果: Article › 査読

  • Superoxide Dismutase-1 100%
  • Exons 65%
  • Amyotrophic Lateral Sclerosis 56%
  • RNA 54%
  • Amyotrophic lateral sclerosis 1 35%
  9 被引用数 (Scopus)

• A novel function of synapsin II in neurotransmitter release

  Sugiyama, T., Shinoe, T., Ito, Y., Misawa, H., Tojima, T., Ito, E. & Yoshioka, T., 2000 12月 28, In: Molecular Brain Research. 85, 1-2, p. 133-143 11 p.

  研究成果: Article › 査読

  • Synapsins 100%
  • Synaptic Vesicles 65%
  • Neurotransmitter Agents 61%
  • FM1 43 22%
  • Cell Body 14%
  19 被引用数 (Scopus)
• 1999

  Constitutive expression of mRNA for the same choline acetyltransferase as that in the nervous system, an acetylcholine-synthesizing enzyme, in human leukemic T-cell lines

  Fujii, T., Tajima, S., Yamada, S., Watanabe, Y., Sato, K. Z., Matsui, M., Misawa, H., Kasahara, T. & Kawashima, K., 1999 1月 8, In: Neuroscience Letters. 259, 2, p. 71-74 4 p.

  研究成果: Article › 査読

  • Choline O-Acetyltransferase 100%
  • Acetylcholine 75%
  • Nervous System 66%
  • T-Lymphocytes 50%
  • Cell Line 48%
  51 被引用数 (Scopus)

• Identification and transgenic analysis of a murine promoter that targets cholinergic neuron expression

  Naciff, J. M., Behbehani, M. M., Misawa, H. & Dedman, J. R., 1999, In: Journal of Neurochemistry. 72, 1, p. 17-28 12 p.

  研究成果: Article › 査読

  • Cholinergic 100%
  • Choline O-Acetyltransferase 96%
  • Cholinergic Neurons 95%
  • Choline 84%
  • Vesicular Acetylcholine Transport Proteins 35%
  34 被引用数 (Scopus)

• Transfection analysis of functional roles of complexin I and II in the exocytosis of two different types of secretory vesicles

  Itakura, M., Misawa, H., Sekiguchi, M., Takahashi, S. & Takahashi, M., 1999 11月 30, In: Biochemical and Biophysical Research Communications. 265, 3, p. 691-696 6 p.

  研究成果: Article › 査読

  • complexin I 100%
  • complexin II 98%
  • Secretory Vesicles 57%
  • Exocytosis 55%
  • Acetylcholine 53%
  64 被引用数 (Scopus)
• 1998

  Acetylcholine synthesis and muscarinic receptor subtype mRNA expression in T-lymphocytes

  Kawashima, K., Fujii, T., Watanabe, Y. & Misawa, H., 1998 3月 27, In: Life Sciences. 62, 17-18, p. 1701-1705 5 p.

  研究成果: Article › 査読

  • Parasympathomimetic Agent 100%
  • Muscarinic Receptors 87%
  • Acetylcholine 85%
  • T-Lymphocytes 49%
  • Messenger RNA 45%
  84 被引用数 (Scopus)

• Induction of choline acetyltransferase mRNA in human mononuclear leukocytes stimulated by phytohemagglutinin, a T-cell activator

  Fujii, T., Yamada, S., Watanabe, Y., Misawa, H., Tajima, S., Fujimoto, K., Kasahara, T. & Kawashima, K., 1998 2月, In: Journal of Neuroimmunology. 82, 1, p. 101-107 7 p.

  研究成果: Article › 査読

  • Mononuclear Leukocytes 100%
  • Choline O-Acetyltransferase 89%
  • Phytohemagglutinins 82%
  • Acetylcholine 67%
  • T-Lymphocytes 45%
  83 被引用数 (Scopus)

• Loss of cholinergic synapses on the spinal motor neurons of amyotrophic lateral sclerosis

  Nagao, M., Misawa, H., Kato, S. & Hirai, S., 1998 4月, In: Journal of Neuropathology and Experimental Neurology. 57, 4, p. 329-333 5 p.

  研究成果: Article › 査読

  Open Access

  • Amyotrophic Lateral Sclerosis 100%
  • Amyotrophic lateral sclerosis 1 93%
  • Motor Neurons 90%
  • Cholinergic Agents 87%
  • Synapses 85%
  55 被引用数 (Scopus)
• 1997

  Changes of expression levels of choline acetyltransferase and vesicular acetylcholine transporter mRNAs after transection of the hypoglossal nerve in adult rats

  Matsuura, J., Ajiki, K., Ichikawa, T. & Misawa, H., 1997 10月 31, In: Neuroscience Letters. 236, 2, p. 95-98 4 p.

  研究成果: Article › 査読

  • Hypoglossal Nerve Injuries 100%
  • Vesicular Acetylcholine Transport Proteins 86%
  • Choline O-Acetyltransferase 67%
  • Messenger RNA 31%
  • Cholinergic Neurons 13%
  24 被引用数 (Scopus)

• Characterization of the 5′-noncoding region of the mouse choline acetyltransferase gene in transgenic mice

  Naciff, J. M., Behbehani, M. M., Misawa, H. & Dedman, J. R., 1997 12月 1, In: FASEB Journal. 11, 3, p. A452

  研究成果: Article › 査読

  • Cholinergic 100%
  • Choline O-Acetyltransferase 96%
  • Choline 84%
  • Transgenic Mice 70%
  • Cholinergic Agents 52%

• Evidence for active acetylcholine metabolism in human amniotic epithelial cells: Applicable to intracerebral allografting for neurologic disease

  Sakuragawa, N., Misawa, H., Ohsugi, K., Kakishita, K., Ishii, T., Thangavel, R., Tohyama, J., Elwan, M., Yokoyama, Y., Okuda, O., Arai, H., Ogino, I. & Sato, K., 1997 8月 22, In: Neuroscience Letters. 232, 1, p. 53-56 4 p.

  研究成果: Article › 査読

  • Homologous Transplantation 100%
  • Nervous System Diseases 83%
  • Acetylcholine 82%
  • Epithelial Cells 63%
  • Lysosomal Storage Diseases 24%
  97 被引用数 (Scopus)

• Human choline acetyltransferase mRNAs with different 5′-region produce a 69-kDa major translation product

  Misawa, H., Matsuura, J., Oda, Y., Takahashi, R. & Deguchi, T., 1997, In: Molecular Brain Research. 44, 2, p. 323-333 11 p.

  研究成果: Article › 査読

  • Choline O-Acetyltransferase 100%
  • Messenger RNA 46%
  • Initiator Codon 33%
  • Haplorhini 16%
  • Enzymes 14%
  54 被引用数 (Scopus)

• Localization of two cholinergic markers, choline acetyltransferase and vesicular acetylcholine transporter in the central nervous system of the rat: In situ hybridization histochemistry and immunohistochemistry

  Ichikawa, T., Ajiki, K., Matsuura, J. & Misawa, H., 1997 6月, In: Journal of Chemical Neuroanatomy. 13, 1, p. 23-39 17 p.

  研究成果: Article › 査読

  • Vesicular Acetylcholine Transport Proteins 100%
  • Choline O-Acetyltransferase 78%
  • Cholinergic Agents 59%
  • In Situ Hybridization 58%
  • Central Nervous System 47%
  195 被引用数 (Scopus)

• Molecular characterization of the mouse vesicular acetylcholine transporter gene

  Naciff, J. M., Misawa, H. & Dedman, J. R., 1997, In: NeuroReport. 8, 16, p. 3467-3473 7 p.

  研究成果: Article › 査読

  • Vesicular Acetylcholine Transport Proteins 100%
  • Choline O-Acetyltransferase 78%
  • Transgenic Mice 28%
  • Genes 25%
  • 5' Flanking Region 19%
  41 被引用数 (Scopus)
• 1996

  A subtype of κ-opioid receptor mediates inhibition of high-affinity GTPase inherent in G_i1 in Guinea pig cerebellar membranes

  Ueda, H., Misawa, H., Fukushima, N., Katada, T., Ui, M. & Satoh, M., 1996 2月, In: Journal of Neurochemistry. 66, 2, p. 845-851 7 p.

  研究成果: Article › 査読

  • GTP Phosphohydrolases 100%
  • Opioid Receptors 97%
  • (trans)-Isomer 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide 90%
  • Toxin 83%
  • Ethylmaleimide 77%
  9 被引用数 (Scopus)
• 1995

  A subtype of opioid κ-receptor is coupled to inhibition of Gil-mediated phospholipase C activity in the guinea pig cerebellum

  Misawa, H., Ueda, H., Katada, T., Ui, M. & Satoh, M., 1995 3月 13, In: FEBS Letters. 361, 1, p. 106-110 5 p.

  研究成果: Article › 査読

  • Opioid Receptors 100%
  • Type C Phospholipases 99%
  • Agent Interacting With Transmitter, Hormone or Drug Receptor 99%
  • Cerebellum 82%
  • Guinea Pigs 78%
  23 被引用数 (Scopus)

• cDNA cloning and chromosomal localization of the human ciliary neurotrophic factor gene

  Yokoji, H., Ariyama, T., Takahashi, R., Inazawa, J., Misawa, H. & Deguchi, T., 1995 2月 13, In: Neuroscience Letters. 185, 3, p. 175-178 4 p.

  研究成果: Article › 査読

  • Ciliary Neurotrophic Factor 100%
  • Organism Cloning 65%
  • Complementary DNA 57%
  • Chromosomes, Human, Pair 11 30%
  • Polyadenylation 30%
  2 被引用数 (Scopus)

• Coordinate expression of vesicular acetylcholine transporter and choline acetyltransferase in sympathetic superior cervical neurones

  Misawa, H., Takahashi, R. & Deguchi, T., 1995 5月, In: NeuroReport. 6, 7, p. 965-968 4 p.

  研究成果: Article › 査読

  • Vesicular Acetylcholine Transport Proteins 100%
  • Choline O-Acetyltransferase 78%
  • Neurons 39%
  • Messenger RNA 31%
  • Leukemia Inhibitory Factor 24%
  74 被引用数 (Scopus)

• Discrete acetylcholine release from neuroblastoma or hybrid cells overexpressing choline acetyltransferase into the neuromuscular synaptic cleft

  Zhong, Z. G., Kimura, Y., Noda, M., Misawa, H. & Higashida, H., 1995 3月, In: Neuroscience Research. 22, 1, p. 81-88 8 p.

  研究成果: Article › 査読

  • Choline O-Acetyltransferase 100%
  • Hybrid Cells 98%
  • Neuroblastoma 81%
  • Acetylcholine 75%
  • Skeletal Muscle Fibers 30%
  13 被引用数 (Scopus)

• Overexpression of choline acetyltransferase reconstitutes discrete acetylcholine release in some but not all synapse formation-defective neuroblastoma cells

  Zhong, ZG. G., Misawa, H., Furuya, S., Kimura, Y., Noda, M., Yokoyama, S. & Higashid, H., 1995, In: Journal of Physiology - Paris. 89, 3, p. 137-145 9 p.

  研究成果: Article › 査読

  • Choline O-Acetyltransferase 100%
  • Neuroblastoma 81%
  • Acetylcholine 75%
  • Synapses 74%
  • Skeletal Muscle Fibers 30%
  14 被引用数 (Scopus)
• 1994

  A null mutation in the human CNTF gene is not causally related to neurological diseases

  Takahashi, R., Yokoji, H., Misawa, H., Hayashi, M., Hu, J. & Deguchi, T., 1994 5月, In: Nature genetics. 7, 1, p. 79-84 6 p.

  研究成果: Article › 査読

  • Ciliary Neurotrophic Factor 100%
  • Loss of Function Mutation 80%
  • Homozygote 52%
  • Alleles 34%
  • RNA Splice Sites 29%
  177 被引用数 (Scopus)

• Calcium‐Independent Release of Acetylcholine from Stable Cell Lines Expressing Mouse Choline Acetyltransferase cDNA

  Misawa, H., Takahashi, R. & Deguchi, T., 1994 2月, In: Journal of Neurochemistry. 62, 2, p. 465-470 6 p.

  研究成果: Article › 査読

  • Choline O-Acetyltransferase 100%
  • Choline 87%
  • Acetylcholine 86%
  • Complementary DNA 84%
  • Cell Line 48%
  18 被引用数 (Scopus)

• Differentiation of cholinergic neurons and physiological role of ciliary neurotrophic factor (CNTF)

  Deguchi, T., Misawa, H. & Takahashi, R., 1994, In: Journal of Physiology - Paris. 88, 4, p. 229-233 5 p.

  研究成果: Article › 査読

  • Ciliary Neurotrophic Factor 100%
  • Cholinergic Neurons 86%
  • Messenger RNA 36%
  • Choline O-Acetyltransferase 29%
  • Loss of Function Mutation 17%
  1 被引用数 (Scopus)

• Reply to “CNTF in the embryo”

  Takahashi, R., Misawa, H. & Deguchi, T., 1994, In: Nature Genetics. 7, 4, p. 460 1 p.

  研究成果: Article › 査読
• 1993

  Multiple mRNA species of choline acetyltransferase from rat spinal cord

  Kengaku, M., Misawa, H. & Deguchi, T., 1993 4月, In: Molecular Brain Research. 18, 1-2, p. 71-76 6 p.

  研究成果: Article › 査読

  • Choline O-Acetyltransferase 100%
  • Spinal Cord 66%
  • Complementary DNA 65%
  • Messenger RNA 46%
  • Clone Cells 27%
  78 被引用数 (Scopus)

• Transcriptional Regulation of Choline Acetyltransferase Gene by Cyclic AMP

  Misawa, H., Takahashi, R. & Deguchi, T., 1993 4月, In: Journal of Neurochemistry. 60, 4, p. 1383-1387 5 p.

  研究成果: Article › 査読

  • Choline O-Acetyltransferase 100%
  • Choline 87%
  • Cyclic AMP 79%
  • Genes 32%
  • Bucladesine 30%
  41 被引用数 (Scopus)
• 1992

  Gene expression of mouse choline acetyltransferase. Alternative splicing and identification of a highly active promoter region

  Misawa, H., Ishii, K. & Deguchi, T., 1992, In: Journal of Biological Chemistry. 267, 28, p. 20392-20399 8 p.

  研究成果: Article › 査読

  • Choline O-Acetyltransferase 100%
  • Alternative Splicing 88%
  • Choline 87%
  • Genetic Promoter Regions 78%
  • Gene Expression 48%
  107 被引用数 (Scopus)
• 1990

  Functional Reconstitution of Purified G_i and G_o with μ‐Opioid Receptors in Guinea Pig Striatal Membranes Pretreated with Micromolar Concentrations of N‐Ethylmaleimide

  Ueda, H., Misawa, H., Katada, T., Ui, M., Takagi, H. & Satoh, M., 1990 3月, In: Journal of Neurochemistry. 54, 3, p. 841-848 8 p.

  研究成果: Article › 査読

  • Opioid Receptors 100%
  • Corpus Striatum 87%
  • Agonist 85%
  • Guinea Pigs 78%
  • Membranes 53%
  54 被引用数 (Scopus)

• κ-Opioid agonist inhibits phospholipase C, possibly via an inhibition of G-protein activity

  Misawa, H., Ueda, H. & Satoh, M., 1990 5月 4, In: Neuroscience Letters. 112, 2-3, p. 324-327 4 p.

  研究成果: Article › 査読

  • Type C Phospholipases 100%
  • GTP-Binding Proteins 89%
  • Opioid Analgesics 79%
  • (trans)-Isomer 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide 69%
  • Synaptic Membranes 59%
  31 被引用数 (Scopus)