三澤 日出巳

研究成果

年別の研究成果 1987 1994 1995 1997 2004 2007 2008 2012 2016 2017 2018 2020 2022

• 5401 被引用数
• 41 h-index
• 103 Article
• 5 Review article
• 1 Conference contribution
• 1 Comment/debate

年別の研究成果

年別の研究成果

検索結果

• Immune system expression of SLURP-1 and SLURP-2, two endogenous nicotinic acetylcholine receptor ligands

  Moriwaki, Y., Yoshikawa, K., Fukuda, H., Fujii, Y. X., Misawa, H. & Kawashima, K., 2007 5月 30, In: Life Sciences. 80, 24-25, p. 2365-2368 4 p.

  研究成果: Article › 査読

  • Nicotinic Receptors 100%
  • Acetylcholine 96%
  • Immune System 71%
  • Ligands 64%
  • Messenger RNA 51%
  71 被引用数 (Scopus)

• Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis

  Tokuda, E., Anzai, I., Nomura, T., Toichi, K., Watanabe, M., Ohara, S., Watanabe, S., Yamanaka, K., Morisaki, Y., Misawa, H. & Furukawa, Y., 2017 1月 5, In: Molecular Neurodegeneration. 12, 1, 2.

  研究成果: Article › 査読

  • Superoxide Dismutase-1 100%
  • Amyotrophic Lateral Sclerosis 84%
  • Disulfides 83%
  • Antibodies 43%
  • Motor Neurons 38%
  14 被引用数 (Scopus)

• Induced loss of ADAR2 engenders slow death of motor neurons from Q/R site-unedited GluR2

  Hideyama, T., Yamashita, T., Suzuki, T., Tsuji, S., Higuchi, M., Seeburg, P. H., Takahashi, R., Misawa, H. & Kwak, S., 2010 9月 8, In: Journal of Neuroscience. 30, 36, p. 11917-11925 9 p.

  研究成果: Article › 査読

  • Adenosine Deaminase 100%
  • Motor Neurons 76%
  • AMPA Receptors 56%
  • RNA 55%
  • Oculomotor Nerve 22%
  111 被引用数 (Scopus)

• Induction of choline acetyltransferase mRNA in human mononuclear leukocytes stimulated by phytohemagglutinin, a T-cell activator

  Fujii, T., Yamada, S., Watanabe, Y., Misawa, H., Tajima, S., Fujimoto, K., Kasahara, T. & Kawashima, K., 1998 2月, In: Journal of Neuroimmunology. 82, 1, p. 101-107 7 p.

  研究成果: Article › 査読

  • Mononuclear Leukocytes 100%
  • Choline O-Acetyltransferase 89%
  • Phytohemagglutinins 82%
  • Acetylcholine 67%
  • T-Lymphocytes 45%
  83 被引用数 (Scopus)

• Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes

  Komine, O., Yamashita, H., Fujimori-Tonou, N., Koike, M., Jin, S., Moriwaki, Y., Endo, F., Watanabe, S., Uematsu, S., Akira, S., Uchiyama, Y., Takahashi, R., Misawa, H. & Yamanaka, K., 2018 12月 1, In: Cell Death and Differentiation. 25, 12, p. 2130-2146 17 p.

  研究成果: Article › 査読

  • Deficiency Diseases 100%
  • Amyotrophic Lateral Sclerosis 77%
  • Astrocytes 66%
  • Disease Progression 57%
  • Myeloid Differentiation Factor 88 42%
  21 被引用数 (Scopus)

• Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases

  Yamamotoya, T., Hasei, S., Akasaka, Y., Ohata, Y., Nakatsu, Y., Kanna, M., Fujishiro, M., Sakoda, H., Ono, H., Kushiyama, A., Misawa, H. & Asano, T., 2022 12月, In: Scientific reports. 12, 1, 1966.

  研究成果: Article › 査読

  Open Access

  • Neurodegenerative Diseases 100%
  • Muscles 69%
  • Neuromuscular Junction 57%
  • Motor Neurons 47%
  • Genes 46%

• Klf4 regulates the expression of slurp1, which functions as an immunomodulatory peptide in the mouse cornea

  Swamynathan, S., Buela, K. A., Kinchington, P., Lathrop, K. L., Misawa, H., Hendricks, R. L. & Swamynathan, S. K., 2012 12月, In: Investigative Ophthalmology and Visual Science. 53, 13, p. 8433-8446 14 p.

  研究成果: Article › 査読

  • GKLF protein 100%
  • Cornea 59%
  • Peptides 40%
  • Human Herpesvirus 1 27%
  • Proteins 23%
  29 被引用数 (Scopus)

• L347P PINK1 mutant that fails to bind to Hsp90/Cdc37 chaperones is rapidly degraded in a proteasome-dependent manner

  Moriwaki, Y., Kim, Y. J., Ido, Y., Misawa, H., Kawashima, K., Endo, S. & Takahashi, R., 2008 5月, In: Neuroscience Research. 61, 1, p. 43-48 6 p.

  研究成果: Article › 査読

  • Proteasome Endopeptidase Complex 100%
  • Phosphotransferases 74%
  • geldanamycin 20%
  • Novobiocin 20%
  • Molecular Chaperones 16%
  64 被引用数 (Scopus)

• Localization of acetylcholine-related molecules in the retina: Implication of the communication from photoreceptor to retinal pigment epithelium

  Matsumoto, H., Shibasaki, K., Uchigashima, M., Koizumi, A., Kurachi, M., Moriwaki, Y., Misawa, H., Kawashima, K., Watanabe, M., Kishi, S. & Ishizaki, Y., 2012 8月 3, In: PloS one. 7, 8, e42841.

  研究成果: Article › 査読

  • Retinal Pigment 100%
  • Retinal Pigment Epithelium 84%
  • photoreceptors 75%
  • acetylcholine 74%
  • retina 72%
  19 被引用数 (Scopus)

• Localization of two cholinergic markers, choline acetyltransferase and vesicular acetylcholine transporter in the central nervous system of the rat: In situ hybridization histochemistry and immunohistochemistry

  Ichikawa, T., Ajiki, K., Matsuura, J. & Misawa, H., 1997 6月, In: Journal of Chemical Neuroanatomy. 13, 1, p. 23-39 17 p.

  研究成果: Article › 査読

  • Vesicular Acetylcholine Transport Proteins 100%
  • Choline O-Acetyltransferase 78%
  • Cholinergic Agents 59%
  • In Situ Hybridization 58%
  • Central Nervous System 47%
  195 被引用数 (Scopus)

• Loss of cholinergic synapses on the spinal motor neurons of amyotrophic lateral sclerosis

  Nagao, M., Misawa, H., Kato, S. & Hirai, S., 1998 4月, In: Journal of Neuropathology and Experimental Neurology. 57, 4, p. 329-333 5 p.

  研究成果: Article › 査読

  Open Access

  • Amyotrophic Lateral Sclerosis 100%
  • Amyotrophic lateral sclerosis 1 93%
  • Motor Neurons 90%
  • Cholinergic Agents 87%
  • Synapses 85%
  54 被引用数 (Scopus)

• Loss of TDP-43 causes age-dependent progressive motor neuron degeneration

  Iguchi, Y., Katsuno, M., Niwa, J. I., Takagi, S., Ishigaki, S., Ikenaka, K., Kawai, K., Watanabe, H., Yamanaka, K., Takahashi, R., Misawa, H., Sasaki, S., Tanaka, F. & Sobue, G., 2013 5月, In: Brain. 136, 5, p. 1371-1382 12 p.

  研究成果: Article › 査読

  • Nerve Degeneration 100%
  • Motor Neurons 77%
  • DNA-Binding Proteins 66%
  • Amyotrophic Lateral Sclerosis 42%
  • Amyotrophic lateral sclerosis 1 26%
  109 被引用数 (Scopus)

• miRNA malfunction causes spinal motor neuron disease

  Haramati, S., Chapnik, E., Sztainberg, Y., Eilam, R., Zwang, R., Gershoni, N., McGlinn, E., Heiser, P. W., Wills, A. M., Wirguin, I., Rubin, L. L., Misawa, H., Tabin, C. J., Brown, R., Chen, A. & Hornstein, E., 2010 7月 20, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 29, p. 13111-13116 6 p.

  研究成果: Article › 査読

  • Motor Neuron Disease 100%
  • MicroRNAs 67%
  • Motor Neurons 61%
  • Spinal Muscular Atrophy 41%
  • Intermediate Filaments 35%
  232 被引用数 (Scopus)

• Modulating lipid metabolism helps axon regeneration

  Yonezu, Y., Misawa, H. & Muramatsu, R., 2020, In: Folia Pharmacologica Japonica. 155, 5, p. 354 1 p.

  研究成果: Article › 査読

• Molecular characterization of the mouse vesicular acetylcholine transporter gene

  Naciff, J. M., Misawa, H. & Dedman, J. R., 1997, In: NeuroReport. 8, 16, p. 3467-3473 7 p.

  研究成果: Article › 査読

  • Vesicular Acetylcholine Transport Proteins 100%
  • Choline O-Acetyltransferase 78%
  • Transgenic Mice 28%
  • Genes 25%
  • 5' Flanking Region 19%
  41 被引用数 (Scopus)

• Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis

  Tashiro, Y., Urushitani, M., Inoue, H., Koike, M., Uchiyama, Y., Komatsu, M., Tanaka, K., Yamazaki, M., Abe, M., Misawa, H., Sakimura, K., Ito, H. & Takahashia, R., 2012 12月 14, In: Journal of Biological Chemistry. 287, 51, p. 42984-42994 11 p.

  研究成果: Article › 査読

  • Amyotrophic Lateral Sclerosis 100%
  • Proteasome Endopeptidase Complex 97%
  • Motor Neurons 90%
  • Autophagy 89%
  • DNA-Binding Proteins 44%
  128 被引用数 (Scopus)

• Multiple mRNA species of choline acetyltransferase from rat spinal cord

  Kengaku, M., Misawa, H. & Deguchi, T., 1993 4月, In: Molecular Brain Research. 18, 1-2, p. 71-76 6 p.

  研究成果: Article › 査読

  • Choline O-Acetyltransferase 100%
  • Spinal Cord 66%
  • Complementary DNA 65%
  • Messenger RNA 46%
  • Clone Cells 27%
  78 被引用数 (Scopus)

• Myelinating cocultures of rodent stem cell line-derived neurons and immortalized Schwann cells

  Ishii, T., Kawakami, E., Endo, K., Misawa, H. & Watabe, K., 2017 10月, In: Neuropathology. 37, 5, p. 475-481 7 p.

  研究成果: Article › 査読

  • Schwann Cells 100%
  • Coculture Techniques 88%
  • Rodentia 73%
  • Stem Cells 65%
  • Neurons 54%
  12 被引用数 (Scopus)

• Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons

  Lasiene, J., Komine, O., Fujimori-Tonou, N., Powers, B., Endo, F., Watanabe, S., Shijie, J., Ravits, J., Horner, P., Misawa, H. & Yamanaka, K., 2016 2月 18, In: Acta Neuropathologica Communications. 4, p. 15 1 p.

  研究成果: Article › 査読

  • Neuregulin-1 100%
  • Superoxide Dismutase-1 89%
  • Amyotrophic Lateral Sclerosis 76%
  • Neuroprotection 74%
  • Motor Neurons 68%
  30 被引用数 (Scopus)

• Neurotransmitter release regulated by a MALS-liprin-α presynaptic complex

  Olsen, O., Moore, K. A., Fukata, M., Kazuta, T., Trinidad, J. C., Kauer, F. W., Streuli, M., Misawa, H., Burlingame, A. L., Nicoll, R. A. & Bredt, D. S., 2005 9月 26, In: Journal of Cell Biology. 170, 7, p. 1127-1134 8 p.

  研究成果: Article › 査読

  • Neurotransmitter Agents 100%
  • Adhesives 53%
  • Synapses 52%
  • Mentha 43%
  • Proteins 42%
  100 被引用数 (Scopus)

• Non-neuronal cholinergic system in regulation of immune function with a focus on α7 nAChRs

  Kawashima, K., Fujii, T., Moriwaki, Y., Misawa, H. & Horiguchi, K., 2015 2月 8, In: International Immunopharmacology. 29, 1, p. 127-134 8 p.

  研究成果: Article › 査読

  • Non-Neuronal Cholinergic System 100%
  • Acetylcholine 50%
  • T-Lymphocytes 26%
  • Choline O-Acetyltransferase 14%
  • Dendritic Cells 10%
  59 被引用数 (Scopus)

• Novel analogs of choline as potential neuroprotective agents

  Buccafusco, J. J., Beach, J. W., Terry, A. V., Doad, G. S., Sood, A., Arias, E., Misawa, H., Masai, M., Fujii, T. & Kawashima, K., 2004 1月 1, In: Journal of Alzheimer's Disease. 6, SUPPL., p. S85-S92

  研究成果: Article › 査読

  • Choline 100%
  • PC 96%
  • Neuroprotective Agents 95%
  • withdrawal 89%
  • nicotine 88%
  8 被引用数 (Scopus)

• Osteopontin is an alpha motor neuron marker in the mouse spinal cord

  Misawa, H., Hara, M., Tanabe, S., Niikura, M., Moriwaki, Y. & Okuda, T., 2012 4月, In: Journal of neuroscience research. 90, 4, p. 732-742 11 p.

  研究成果: Article › 査読

  • Osteopontin 100%
  • Motor Neurons 81%
  • Spinal Cord 69%
  • Choline O-Acetyltransferase 57%
  • Carisoprodol 30%
  20 被引用数 (Scopus)

• Overexpression of choline acetyltransferase reconstitutes discrete acetylcholine release in some but not all synapse formation-defective neuroblastoma cells

  Zhong, ZG. G., Misawa, H., Furuya, S., Kimura, Y., Noda, M., Yokoyama, S. & Higashid, H., 1995, In: Journal of Physiology - Paris. 89, 3, p. 137-145 9 p.

  研究成果: Article › 査読

  • Choline O-Acetyltransferase 100%
  • Neuroblastoma 81%
  • Acetylcholine 75%
  • Synapses 74%
  • Skeletal Muscle Fibers 30%
  14 被引用数 (Scopus)

• Oxidative misfolding of Cu/Zn-superoxide dismutase triggered by non-canonical intramolecular disulfide formation

  Anzai, I., Tokuda, E., Handa, S., Misawa, H., Akiyama, S. & Furukawa, Y., 2020 2月 1, In: Free Radical Biology and Medicine. 147, p. 187-199 13 p.

  研究成果: Article › 査読

  • Superoxide Dismutase-1 100%
  • Disulfides 83%
  • Disulfide 64%
  • Amyotrophic Lateral Sclerosis 56%
  • Sulfenic Acids 48%
  6 被引用数 (Scopus)

• Primary sensory neuronal expression of SLURP-1, an endogenous nicotinic acetylcholine receptor ligand

  Moriwaki, Y., Watanabe, Y., Shinagawa, T., Kai, M., Miyazawa, M., Okuda, T., Kawashima, K., Yabashi, A., Waguri, S. & Misawa, H., 2009 8月, In: Neuroscience Research. 64, 4, p. 403-412 10 p.

  研究成果: Article › 査読

  • Urokinase Plasminogen Activator Receptors 100%
  • Nicotinic Receptors 79%
  • Ligands 50%
  • Spinal Cord Dorsal Horn 30%
  • Proteins 26%
  49 被引用数 (Scopus)

• Purified opioid μ-receptor is of a different molecular size than δ- and κ-receptors

  Ueda, H., Harada, H., Misawa, H., Nozaki, M. & Takagi, H., 1987 4月 10, In: Neuroscience Letters. 75, 3, p. 339-344 6 p.

  研究成果: Article › 査読

  • Opioid Receptors 100%
  • Opioid Analgesics 79%
  • Carrier Proteins 75%
  • Ala(2)-MePhe(4)-Gly(5)-enkephalin 65%
  • Octoxynol 53%
  18 被引用数 (Scopus)

• Reappraisal of VAChT-Cre: Preference in slow motor neurons innervating type I or IIa muscle fibers

  Misawa, H., Inomata, D., Kikuchi, M., Maruyama, S., Moriwaki, Y., Okuda, T., Nukina, N. & Yamanaka, T., 2016 11月 1, In: Genesis. 54, 11, p. 568-572 5 p.

  研究成果: Article › 査読

  • Motor Neurons 100%
  • Muscles 62%
  • Fatigue 37%
  • Fluorescence 36%
  • Presynaptic Terminals 32%
  2 被引用数 (Scopus)

• Reconciling neuronally and nonneuronally derived acetylcholine in the regulation of immune function

  Kawashima, K., Fujii, T., Moriwaki, Y., Misawa, H. & Horiguchi, K., 2012 7月, In: Annals of the New York Academy of Sciences. 1261, 1, p. 7-17 11 p.

  研究成果: Article › 査読

  • Acetylcholine 100%
  • Cells 65%
  • T-Lymphocytes 57%
  • Cholinergic 29%
  • Parasympathomimetic Agent 29%
  58 被引用数 (Scopus)

• Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice

  Olsen, O., Funke, L., Long, J. F., Fukata, M., Kazuta, T., Trinidad, J. C., Moore, K. A., Misawa, H., Welling, P. A., Burlingame, A. L., Zhang, M. & Bredt, D. S., 2007 10月 8, In: Journal of Cell Biology. 179, 1, p. 151-164 14 p.

  研究成果: Article › 査読

  • Knockout Mice 100%
  • Epithelium 59%
  • Kidney 58%
  • Cystic Kidney Diseases 43%
  • Cell Polarity 19%
  36 被引用数 (Scopus)

• Reply to “CNTF in the embryo”

  Takahashi, R., Misawa, H. & Deguchi, T., 1994, In: Nature Genetics. 7, 4, p. 460 1 p.

  研究成果: Article › 査読

• Role of GluR1 in activity-dependent motor system development

  Zhang, L., Schessl, J., Werner, M., Bonnemann, C., Xiong, G., Mojsilovic-Petrovic, J., Zhou, W., Cohen, A., Seeburg, P., Misawa, H., Jayaram, A., Personius, K., Hollmann, M., Sprengel, R. & Kalb, R., 2008 10月 1, In: Journal of Neuroscience. 28, 40, p. 9953-9968 16 p.

  研究成果: Article › 査読

  • Motor Activity 100%
  • Dendrites 96%
  • Motor Neurons 90%
  • Spinal Cord 76%
  • AMPA 1 glutamate receptor ionotropic 52%
  18 被引用数 (Scopus)

• Selective disruption of acetylcholine synthesis in subsets of motor neurons: A new model of late-onset motor neuron disease

  Lecomte, M. J., Bertolus, C., Santamaria, J., Bauchet, A. L., Herbin, M., Saurini, F., Misawa, H., Maisonobe, T., Pradat, P. F., Nosten-Bertrand, M., Mallet, J. & Berrard, S., 2014 5月, In: Neurobiology of Disease. 65, p. 102-111 10 p.

  研究成果: Article › 査読

  • Motor Neuron Disease 100%
  • Motor Neurons 77%
  • Acetylcholine 74%
  • Choline O-Acetyltransferase 49%
  • Gene Knockout Techniques 16%
  6 被引用数 (Scopus)

• Selective expression of osteopontin in ALS-resistant motor neurons is a critical determinant of late phase neurodegeneration mediated by matrix metalloproteinase-9

  Morisaki, Y., Niikura, M., Watanabe, M., Onishi, K., Tanabe, S., Moriwaki, Y., Okuda, T., Ohara, S., Murayama, S., Takao, M., Uchida, S., Yamanaka, K. & Misawa, H., 2016 6月 6, In: Scientific reports. 6, 27354.

  研究成果: Article › 査読

  Open Access

  • Osteopontin 100%
  • Matrix Metalloproteinase 9 90%
  • Amyotrophic Lateral Sclerosis 90%
  • Motor Neurons 81%
  • Fatigue 40%
  29 被引用数 (Scopus)

• SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes

  Moriwaki, Y., Ohno, Y., Ishii, T., Takamura, Y., Kita, Y., Watabe, K., Sango, K., Tsuji, S. & Misawa, H., 2018 6月, In: PloS one. 13, 6, e0199829.

  研究成果: Article › 査読

  • trans-Golgi Network 100%
  • endosomes 91%
  • protein transport 82%
  • Endosomes 81%
  • Protein Transport 81%
  3 被引用数 (Scopus)

• SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system

  Watanabe, S., Ageta-Ishihara, N., Nagatsu, S., Takao, K., Komine, O., Endo, F., Miyakawa, T., Misawa, H., Takahashi, R., Kinoshita, M. & Yamanaka, K., 2014 8月 29, In: Molecular brain. 7, 1, 62.

  研究成果: Article › 査読

  • Sirtuin 1 100%
  • Superoxide Dismutase-1 95%
  • Heat-Shock Response 82%
  • Amyotrophic Lateral Sclerosis 80%
  • Transgenic Mice 53%
  60 被引用数 (Scopus)

• SLURP-1, an endogenous α7 nicotinic acetylcholine receptor allosteric ligand, is expressed in CD205⁺ dendritic cells in human tonsils and potentiates lymphocytic cholinergic activity

  Fujii, T., Horiguchi, K., Sunaga, H., Moriwaki, Y., Misawa, H., Kasahara, T., Tsuji, S. & Kawashima, K., 2014, In: Journal of Neuroimmunology. 267, 1-2, p. 43-49 7 p.

  研究成果: Article › 査読

  • Palatine Tonsil 100%
  • Cholinergic Receptors 95%
  • Nicotinic Receptors 95%
  • Cholinergic Agents 80%
  • Dendritic Cells 77%
  29 被引用数 (Scopus)

• Stagnation of glymphatic interstitial fluid flow and delay in waste clearance in the SOD1-G93A mouse model of ALS

  Hirose, M., Asano, M., Watanabe-Matsumoto, S., Yamanaka, K., Abe, Y., Yasui, M., Tokuda, E., Furukawa, Y. & Misawa, H., 2021 10月, In: Neuroscience Research. 171, p. 74-82 9 p.

  研究成果: Article › 査読

  Open Access

  • Extracellular Fluid 100%
  • Amyotrophic Lateral Sclerosis 94%
  • Aquaporin 4 59%
  • Glymphatic System 34%
  • Spinal Cord 18%
  4 被引用数 (Scopus)

• Substrate-induced internalization of the high-affinity choline transporter

  Okuda, T., Konishi, A., Misawa, H. & Haga, T., 2011 10月 19, In: Journal of Neuroscience. 31, 42, p. 14989-14997 9 p.

  研究成果: Article › 査読

  • choline transporter 100%
  • Acetylcholine 55%
  • Choline 48%
  • Presynaptic Terminals 33%
  • Hemicholinium 3 23%
  16 被引用数 (Scopus)

• Sustained subcutaneous infusion of nicotine enhances cholinergic vasodilation in the cerebral cortex induced by stimulation of the nucleus basalis of Meynert in rats

  Uchida, S., Hotta, H., Misawa, H. & Kawashima, K., 2011 3月 11, In: European journal of pharmacology. 654, 3, p. 235-240 6 p.

  研究成果: Article › 査読

  • Basal Nucleus of Meynert 100%
  • Subcutaneous Infusions 91%
  • Nicotine 68%
  • Vasodilation 66%
  • Cholinergic Agents 64%
  9 被引用数 (Scopus)

• The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model

  Inoue, H., Tsukita, K., Iwasato, T., Suzuki, Y., Tomioka, M., Tateno, M., Nagao, M., Kawata, A., Saido, T. C., Miura, M., Misawa, H., Itohara, S. & Takahashi, R., 2003 12月 15, In: EMBO Journal. 22, 24, p. 6665-6674 10 p.

  研究成果: Article › 査読

  • Apoptotic 100%
  • Caspase 9 98%
  • Amyotrophic Lateral Sclerosis 93%
  • Superoxide 84%
  • Disease Progression 69%
  94 被引用数 (Scopus)

• The in vivo contribution of motor neuron TrkB receptors to mutant SOD1 motor neuron disease

  Zhai, J., Zhou, W., Li, J., Hayworth, C. R., Zhang, L., Misawa, H., Klein, R., Scherer, S. S., Balice-Gordon, R. J. & Kalb, R. G., 2011 11月, In: Human molecular genetics. 20, 21, p. 4116-4131 16 p., ddr335.

  研究成果: Article › 査読

  • tropomyosin kinase 100%
  • Superoxide Dismutase-1 83%
  • Motor Neuron Disease 83%
  • Motor Neurons 64%
  • Brain-Derived Neurotrophic Factor 35%
  18 被引用数 (Scopus)

• The kyotorphin (tyrosine-arginine) receptor and a selective reconstitution with purified G(i), measured with GTPase and phospholipase C assays

  Ueda, H., Yoshihara, Y., Misawa, H., Fukushima, N., Katada, T., Ui, M., Takagi, H. & Satoh, M., 1989, In: Journal of Biological Chemistry. 264, 7, p. 3732-3741 10 p.

  研究成果: Article › 査読

  • kyotorphin 100%
  • tyrosine receptor 79%
  • GTP Phosphohydrolases 62%
  • Type C Phospholipases 60%
  • Arginine 50%
  67 被引用数 (Scopus)

• The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons

  Mori, T., Yuxing, Z., Takaki, H., Takeuchi, M., Iseki, K., Hagino, S., Kitanaka, J. I., Takemura, M., Misawa, H., Ikawa, M., Okabe, M. & Wanaka, A., 2004 6月 1, In: European Journal of Neuroscience. 19, 12, p. 3129-3141 13 p.

  研究成果: Article › 査読

  • Basal Forebrain 100%
  • Cholinergic Neurons 96%
  • Homeobox Genes 92%
  • Vesicular Acetylcholine Transport Proteins 20%
  • Nerve Growth Factor Receptor 17%
  81 被引用数 (Scopus)

• The missing link between long-term stimulation of nicotinic receptors and the increases of acetylcholine release and vasodilation in the cerebral cortex of aged rats

  Uchida, S., Hotta, H., Misawa, H. & Kawashima, K., 2013 3月, In: Journal of Physiological Sciences. 63, 2, p. 95-101 7 p.

  研究成果: Article › 査読

  • Nicotinic Receptors 100%
  • Nicotine 90%
  • Vasodilation 87%
  • Cerebral Cortex 84%
  • Acetylcholine 70%
  6 被引用数 (Scopus)

• The specific opioid κ-agonist U-50,488H inhibits low Km GTPase

  Ueda, H., Misawa, H., Fukushima, N. & Takagi, H., 1987 6月 12, In: European journal of pharmacology. 138, 1, p. 129-132 4 p.

  研究成果: Article › 査読

  • (trans)-Isomer 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide 100%
  • GTP Phosphohydrolases 73%
  • Opioid Analgesics 56%
  • Naloxone 45%
  • Guinea Pigs 37%
  21 被引用数 (Scopus)

• Transcriptional Regulation of Choline Acetyltransferase Gene by Cyclic AMP

  Misawa, H., Takahashi, R. & Deguchi, T., 1993 4月, In: Journal of Neurochemistry. 60, 4, p. 1383-1387 5 p.

  研究成果: Article › 査読

  • Choline O-Acetyltransferase 100%
  • Choline 87%
  • Cyclic AMP 79%
  • Genes 32%
  • Bucladesine 30%
  41 被引用数 (Scopus)

• Transcriptional regulation of SLURP2, a psoriasis-associated gene, is under control of IL-22 in the skin: A special reference to the nested gene LYNX1

  Moriwaki, Y., Takada, K., Tsuji, S., Kawashima, K. & Misawa, H., 2015 2月 12, In: International Immunopharmacology. 29, 1, p. 71-75 5 p.

  研究成果: Article › 査読

  • Nested Genes 100%
  • interleukin-22 73%
  • Psoriasis 53%
  • Keratinocytes 52%
  • Skin 29%
  10 被引用数 (Scopus)

• Transfection analysis of functional roles of complexin I and II in the exocytosis of two different types of secretory vesicles

  Itakura, M., Misawa, H., Sekiguchi, M., Takahashi, S. & Takahashi, M., 1999 11月 30, In: Biochemical and Biophysical Research Communications. 265, 3, p. 691-696 6 p.

  研究成果: Article › 査読

  • complexin I 100%
  • complexin II 98%
  • Secretory Vesicles 57%
  • Exocytosis 55%
  • Acetylcholine 53%
  64 被引用数 (Scopus)

• Ubiquitous expression of acetylcholine and its biological functions in life forms without nervous systems

  Kawashima, K., Misawa, H., Moriwaki, Y., Fujii, Y. X., Fujii, T., Horiuchi, Y., Yamada, T., Imanaka, T. & Kamekura, M., 2007 5月 30, In: Life Sciences. 80, 24-25, p. 2206-2209 4 p.

  研究成果: Article › 査読

  • Acetylcholine 100%
  • Nervous System 76%
  • Shiitake Mushrooms 38%
  • Choline 33%
  • Choline O-Acetyltransferase 28%
  72 被引用数 (Scopus)