Hideyuki Okano

Article

Sox21 is a repressor of neuronal differentiation and is antagonized by YB-1

Ohba, H., Chiyoda, T., Endo, E., Yano, M., Hayakawa, Y., Sakaguchi, M., Darnell, R. B., Okano, H. J. & Okano, H., 2004 4月 1, In: Neuroscience Letters. 358, 3, p. 157-160 4 p.

研究成果: Article › 査読

31 被引用数 (Scopus)

Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene

Matsuda, S., Kuwako, K. I., Okano, H. J., Tsutsumi, S., Aburatani, H., Saga, Y., Matsuzaki, Y., Akaike, A., Sugimoto, H. & Okano, H., 2012 9月 5, In: Journal of Neuroscience. 32, 36, p. 12543-12557 15 p.

研究成果: Article › 査読

52 被引用数 (Scopus)

Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ

Saito, K., Michon, F., Yamada, A., Inuzuka, H., Yamaguchi, S., Fukumoto, E., Yoshizaki, K., Nakamura, T., Arakaki, M., Chiba, Y., Ishikawa, M., Okano, H., Thesleff, I. & Fukumoto, S., 2020 7月 24, In: iScience. 23, 7, 101329.

研究成果: Article › 査読

Open Access

10 被引用数 (Scopus)

Sox6 Up-Regulation by Macrophage Migration Inhibitory Factor Promotes Survival and Maintenance of Mouse Neural Stem/Progenitor Cells

Ohta, S., Misawa, A., Lefebvre, V., Okano, H., Kawakami, Y. & Toda, M., 2013 9月 16, In: PloS one. 8, 9, e74315.

研究成果: Article › 査読

20 被引用数 (Scopus)

Spatiotemporal expression of TRPM4 in the mouse cochlea

Sakuraba, M., Murata, J., Teruyama, R., Kamiya, K., Yamaguchi, J., Okano, H., Uchiyama, Y. & Ikeda, K., 2014 10月, In: Journal of neuroscience research. 92, 10, p. 1409-1418 10 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Spatiotemporal patterns of Musashil expression during inner ear development

Sakaguchi, H., Yaoi, T., Suzuki, T., Okano, H., Hisa, Y. & Fushiki, S., 2004 4月 29, In: NeuroReport. 15, 6, p. 997-1001 5 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells

Okada, Y., Matsumoto, A., Shimazaki, T., Enoki, R., Koizumi, A., Ishii, S., Itoyama, Y., Sobue, G. & Okano, H., 2008 12月, In: Stem Cells. 26, 12, p. 3086-3098 13 p.

研究成果: Article › 査読

145 被引用数 (Scopus)

Sphere-formation culture of testicular germ cells in the common marmoset, a small New World monkey

Lin, Z. Y. C., Hikabe, O., Suzuki, S., Hirano, T., Siomi, H., Sasaki, E., Imamura, M. & Okano, H., 2016 1月 1, In: Primates. 57, 1, p. 129-135 7 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy

Iida, M., Sahashi, K., Kondo, N., Nakatsuji, H., Tohnai, G., Tsutsumi, Y., Noda, S., Murakami, A., Onodera, K., Okada, Y., Nakatochi, M., Tsukagoshi Okabe, Y., Shimizu, S., Mizuno, M., Adachi, H., Okano, H., Sobue, G. & Katsuno, M., 2019 12月 1, In: Nature communications. 10, 1, 4262.

研究成果: Article › 査読

Open Access

10 被引用数 (Scopus)

STAT3: Down the R(h)oAd

Renault-Mihara, F. & Okano, H., 2018 2月, In: Cytokine. 102, p. 149-150 2 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch

Shiratori-Hayashi, M., Koga, K., Tozaki-Saitoh, H., Kohro, Y., Toyonaga, H., Yamaguchi, C., Hasegawa, A., Nakahara, T., Hachisuka, J., Akira, S., Okano, H., Furue, M., Inoue, K. & Tsuda, M., 2015 8月 8, In: Nature medicine. 21, 8, p. 927-931 5 p.

研究成果: Article › 査読

120 被引用数 (Scopus)

Stem cell-like properties of the endometrial side population: Implication in endometrial regeneration

Masuda, H., Matsuzaki, Y., Hiratsu, E., Ono, M., Nagashima, T., Kajitani, T., Arase, T., Oda, H., Uchida, H., Asada, H., Ito, M., Yoshimura, Y., Maruyama, T. & Okano, H., 2010, In: PloS one. 5, 4, e10387.

研究成果: Article › 査読

213 被引用数 (Scopus)

Stem cells purified from human induced pluripotent stem cell-derived neural crest-like cells promote peripheral nerve regeneration

Kimura, H., Ouchi, T., Shibata, S., Amemiya, T., Nagoshi, N., Nakagawa, T., Matsumoto, M., Okano, H., Nakamura, M. & Sato, K., 2018 12月 1, In: Scientific reports. 8, 1, 10071.

研究成果: Article › 査読

Open Access

31 被引用数 (Scopus)

Step-by-step protocols for non-viral derivation of transgene-free induced pluripotent stem cells from somatic fibroblasts of multiple mammalian species

Yoshimatsu, S., Yamazaki, A., Edamura, K., Koushige, Y., Shibuya, H., Qian, E., Sato, T., Okahara, J., Kishi, N., Noce, T., Yamaguchi, Y. & Okano, H., 2022 8月, In: Development Growth and Differentiation. 64, 6, p. 325-341 17 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Stimulation of myelin basic protein gene transcription by fyn tyrosine kinase for myelination

Umemori, H., Kadowaki, Y., Hirosawa, K., Yoshida, Y., Hironaka, K., Okano, H. & Yamamoto, T., 1999 2月 15, In: Journal of Neuroscience. 19, 4, p. 1393-1397 5 p.

研究成果: Article › 査読

Open Access

102 被引用数 (Scopus)

Strategic approaches to regeneration of a damaged central nervous system

Okano, H., 2011 10月 1, In: Cornea. 30, 10 SUPPL. 1, p. S15-S18

研究成果: Article › 査読

7 被引用数 (Scopus)

Strategies toward CNS-regeneration using induced pluripotent stem cells.

Okano, H., 2009 10月, In: Genome informatics. International Conference on Genome Informatics. 23, 1, p. 217-220 4 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex

Yamasaki, T., Kawasaki, H., Arakawa, S., Shimizu, K., Shimizu, S., Reiner, O., Okano, H., Nishina, S., Azuma, N., Penninger, J. M., Katada, T. & Nishina, H., 2011 11月 16, In: Journal of Neuroscience. 31, 46, p. 16872-16883 12 p.

研究成果: Article › 査読

54 被引用数 (Scopus)

Stromal cell-secreted factors promote the survival of embryonic stem cell-derived early neural stem/progenitor cells via the activation of MAPK and PI3K-Akt pathways

Ishii, S., Okada, Y., Kadoya, T., Matsuzaki, Y., Shimazaki, T. & Okano, H., 2010 3月, In: Journal of neuroscience research. 88, 4, p. 722-734 13 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

Structural analysis of Musashi-RNA complex on the basis of long-range structural information.

Ohyama, T., Furukawa, A., Mashima, T., Sugiyama, T., Ohgara, S., Yamazaki, T., Imai, T., Okano, H., Nagata, T. & Katahira, M., 2008 12月 1, In: Nucleic acids symposium series (2004). 52, p. 193-194 2 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA

Iwaoka, R., Nagata, T., Tsuda, K., Imai, T., Okano, H., Kobayashi, N. & Katahira, M., 2017 7月 19, In: Molecules (Basel, Switzerland). 22, 7

研究成果: Article › 査読

Open Access

18 被引用数 (Scopus)

Structural properties and RNA-binding activities of two RNA recognition motifs of a mouse neural RNA-binding protein, mouse-Musashi-1

Kurihara, Y., Nagata, T., Imai, T., Hiwatashi, A., Horiuchi, M., Sakakibara, S. I., Katahira, M., Okano, H. & Uesugi, S., 1997 2月 20, In: Gene. 186, 1, p. 21-27 7 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

Structure, backbone dynamics and interactions with RNA of the C-terminal RNA-binding domain of a mouse neural RNA-binding protein, Musashi1

Nagata, T., Kanno, R., Kurihara, Y., Uesugi, S., Imai, T., Sakakibara, S. I., Okano, H. & Katahira, M., 1999 3月 26, In: Journal of Molecular Biology. 287, 2, p. 315-330 16 p.

研究成果: Article › 査読

44 被引用数 (Scopus)

Structure and Function of Inositol 1,4,5‐Trisphosphate Receptor

MIKOSHIBA, K., FURUICHI, T., MIYAWAKI, A., YOSHIKAWA, S., NAKADE, S., MICHIKAWA, T., NAKAGAWA, T., OKANO, H., KUME, S., MUTO, A., ARUGA, J., YAMADA, N., HAMANAKA, Y., FUJINO, I. & KOBAYASHI, M., 1993 12月, In: Annals of the New York Academy of Sciences. 707, 1, p. 178-197 20 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

Structure of Musashi1 in a complex with target RNA: The role of aromatic stacking interactions

Ohyama, T., Nagata, T., Tsuda, K., Kobayashi, N., Imai, T., Okano, H., Yamazaki, T. & Katahira, M., 2012 4月, In: Nucleic acids research. 40, 7, p. 3218-3231 14 p.

研究成果: Article › 査読

64 被引用数 (Scopus)

Subventricular zone-derived neural progenitor cells migrate along a blood vessel scaffold toward the post-stroke striatum

Kojima, T., Hirota, Y., Ema, M., Takahashi, S., Miyoshi, I., Okano, H. & Sawamoto, K., 2010 3月 31, In: Stem Cells. 28, 3, p. 545-554 10 p.

研究成果: Article › 査読

239 被引用数 (Scopus)

Subventricular zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum

Yamashita, T., Ninomiya, M., Acosta, P. H., García-Verdugo, J. M., Sunabori, T., Sakaguchi, M., Adachi, K., Kojima, T., Hirota, Y., Kawase, T., Araki, N., Abe, K., Okano, H. & Sawamoto, K., 2006, In: Journal of Neuroscience. 26, 24, p. 6627-6636 10 p.

研究成果: Article › 査読

613 被引用数 (Scopus)

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

Hara, T., Nakamura, K., Matsui, M., Yamamoto, A., Nakahara, Y., Suzuki-Migishima, R., Yokoyama, M., Mishima, K., Saito, I., Okano, H. & Mizushima, N., 2006 6月 15, In: Nature. 441, 7095, p. 885-889 5 p.

研究成果: Article › 査読

3120 被引用数 (Scopus)

Suppression of oct4 by germ cell nuclear factor restricts pluripotency and promotes neural stem cell development in the early neural lineage

Akamatsu, W., Deveale, B., Okano, H., Cooney, A. J. & Van Kooy, D. D., 2009 2月 18, In: Journal of Neuroscience. 29, 7, p. 2113-2124 12 p.

研究成果: Article › 査読

63 被引用数 (Scopus)

Sustained bFGF-release tubes for peripheral nerve regeneration: Comparison with autograft

Takagi, T., Kimura, Y., Shibata, S., Saito, H., Ishii, K., Okano, H. J., Toyama, Y., Okano, H., Tabata, Y. & Nakamura, M., 2012 10月, In: Plastic and Reconstructive Surgery. 130, 4, p. 866-876 11 p.

研究成果: Article › 査読

21 被引用数 (Scopus)

Sustained effect of hyaluronic acid in subcutaneous administration to the cochlear spiral ganglion

Inagaki, Y., Fujioka, M., Kanzaki, S., Watanabe, K., Oishi, N., Itakura, G., Yasuda, A., Shibata, S., Nakamura, M., James Okano, H., Okano, H. & Ogawa, K., 2016 4月, In: PloS one. 11, 4, e0153957.

研究成果: Article › 査読

Open Access

4 被引用数 (Scopus)

Symposium 4: Chairman's remark

Okano, H. & Mizusawa, H., 2003 11月 1, In: Clinical Neurology. 43, 11, 1 p.

研究成果: Article › 査読

Synaptic input of ON-bipolar cells onto the dopaminergic neurons of the mouse retina

Contini, M., Lin, B., Kobayashi, K., Okano, H., Masland, R. H. & Raviola, E., 2010 6月 1, In: Journal of Comparative Neurology. 518, 11, p. 2035-2050 16 p.

研究成果: Article › 査読

41 被引用数 (Scopus)

Targeted expression of anti-apoptotic protein p35 in oligodendrocytes reduces delayed demyelination and functional impairment after spinal cord injury

Tamura, M., Nakamura, M., Ogawa, Y., Toyama, Y., Miura, M. & Okano, H., 2005 9月 1, In: Glia. 51, 4, p. 312-321 10 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination

Hisahara, S., Araki, T., Sugiyama, F., Yagami, K. I., Suzuki, M., Abe, K., Yamamura, K. I., Miyazaki, J. I., Momoi, T., Saruta, T., Bernard, C. C. A., Okano, H. & Miura, M., 2000 2月 1, In: EMBO Journal. 19, 3, p. 341-348 8 p.

研究成果: Article › 査読

96 被引用数 (Scopus)

Tau isoform expression and phosphorylation in marmoset brains

Sharma, G., Huo, A., Kimura, T., Shiozawa, S., Kobayashi, R., Sahara, N., Ishibashi, M., Ishigaki, S., Saito, T., Ando, K., Murayama, S., Hasegawa, M., Sobue, G., Okano, H. & Hisanaga, S. I., 2019 7月 26, In: Journal of Biological Chemistry. 294, 30, p. 11433-11444 12 p.

研究成果: Article › 査読

Open Access

14 被引用数 (Scopus)

Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium

Homma, K., Toda, E., Osada, H., Nagai, N., Era, T., Tsubota, K., Okano, H. & Ozawa, Y., 2021 5月, In: Redox Biology. 41, 101921.

研究成果: Article › 査読

Open Access

16 被引用数 (Scopus)

Technical feasibility of visualizing myenteric plexus using confocal laser endomicroscopy

Kobayashi, M., Sumiyama, K., Shimojima, N., Ieiri, S., Okano, H., Kamba, S., Fujimura, T., Hirobe, S., Kuroda, T. & Takahashi-Fujigasaki, J., 2017 9月, In: Journal of Gastroenterology and Hepatology (Australia). 32, 9, p. 1604-1610 7 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

The 43rd Annual Meeting of the Japanese Society of Neurology. Symposium V: Chairman's remark

Sobue, G. & Okano, H., 2002 11月 1, In: Clinical Neurology. 42, 11, 1 p.

研究成果: Article › 査読

The adeno-associated virus rh10 vector is an effective gene transfer system for chronic spinal cord injury

Hoshino, Y., Nishide, K., Nagoshi, N., Shibata, S., Moritoki, N., Kojima, K., Tsuji, O., Matsumoto, M., Kohyama, J., Nakamura, M. & Okano, H., 2019 12月 1, In: Scientific reports. 9, 1, 9844.

研究成果: Article › 査読

Open Access

7 被引用数 (Scopus)

The Amelioration of Pain-Related Behavior in Mice with Chronic Spinal Cord Injury Treated with Neural Stem/Progenitor Cell Transplantation Combined with Treadmill Training

Tashiro, S., Nishimura, S., Shinozaki, M., Takano, M., Konomi, T., Tsuji, O., Nagoshi, N., Toyama, Y., Liu, M., Okano, H. & Nakamura, M., 2018 11月 1, In: Journal of Neurotrauma. 35, 21, p. 2561-2571 11 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

The Anterior Eye Chamber as a Visible Medium for in Vivo Tumorigenicity Tests

Inagaki, E., Arai, E., Hatou, S., Sayano, T., Taniguchi, H., Negishi, K., Kanai, Y., Sato, Y., Okano, H., Tsubota, K. & Shimmura, S., 2022 8月, In: Stem Cells Translational Medicine. 11, 8, p. 841-849 9 p.

研究成果: Article › 査読

Open Access

The bHLH gene Hes1 as a repressor of the neuronal commitment of CNS stem cells

Nakamura, Y., Sakakibara, S. I., Miyata, T., Ogawa, M., Shimazaki, T., Weiss, S., Kageyama, R. & Okano, H., 2000 1月 1, In: Journal of Neuroscience. 20, 1, p. 283-293 11 p.

研究成果: Article › 査読

Open Access

274 被引用数 (Scopus)

The C. elegans septin genes, unc-59 and unc-61, are required for normal postembryonic cytokineses and morphogenesis but have no essential function in embryogenesis

Nguyen, T. Q., Sawa, H., Okano, H. & White, J. G., 2000, In: Journal of Cell Science. 113, 21, p. 3825-3837 13 p.

研究成果: Article › 査読

106 被引用数 (Scopus)

The common marmoset as suitable nonhuman alternative for the analysis of primate cochlear development

Hosoya, M., Fujioka, M., Murayama, A. Y., Okano, H. & Ogawa, K., 2021 1月, In: FEBS Journal. 288, 1, p. 325-353 29 p.

研究成果: Article › 査読

Open Access

8 被引用数 (Scopus)

The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice

Kiso, M., Tanaka, S., Saba, R., Matsuda, S., Shimizu, A., Ohyama, M., Okano, H. J., Shiroishi, T., Okano, H. & Saga, Y., 2009 6月 9, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 23, p. 9292-9297 6 p.

研究成果: Article › 査読

57 被引用数 (Scopus)

The Drosophila ortholog of MLL3 and MLL4, trithorax related, functions as a negative regulator of tissue growth

Kanda, H., Nguyen, A., Chen, L., Okano, H. & Hariharan, I. K., 2013 5月, In: Molecular and cellular biology. 33, 9, p. 1702-1710 9 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH₂-terminal kinase pathway

Sawamoto, K., Winge, P., Koyama, S., Hirota, Y., Yamada, C., Miyao, S., Yoshikawa, S., Jin, M. H., Kikuchi, A. & Okano, H., 1999 7月 26, In: Journal of Cell Biology. 146, 2, p. 361-372 12 p.

研究成果: Article › 査読

43 被引用数 (Scopus)

The Drosophila secreted protein Argos regulates signal transduction in the Ras/MAPK pathway

Sawamoto, K., Okabe, M., Tanimura, T., Mikoshiba, K., Nishida, Y. & Okano, H., 1996 8月 25, In: Developmental Biology. 178, 1, p. 13-22 10 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

The dual origin of the peripheral olfactory system: Placode and neural crest

Katoh, H., Shibata, S., Fukuda, K., Sato, M., Satoh, E., Nagoshi, N., Minematsu, T., Matsuzaki, Y., Akazawa, C., Toyama, Y., Nakamura, M. & Okano, H., 2011, In: Molecular brain. 4, 1, 34.

研究成果: Article › 査読

69 被引用数 (Scopus)

岡野 栄之

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岡野栄之