Hideyuki Okano

1998

Argos induces programmed cell death in the developing Drosophila eye by inhibition of the Ras pathway

Sawamoto, K., Taguchi, A., Hirota, Y., Yamada, C., Jin, M. H. & Okano, H., 1998 4月, In: Cell Death and Differentiation. 5, 4, p. 262-270 9 p.

研究成果: Article › 査読

Open Access

52 被引用数 (Scopus)

Caenorhabditis elegans anti-apoptotic gene ced-9 prevents ced-3-induced cell death in Drosophila cells

Hisahara, S., Kanuka, H., Shoji, S. I., Yoshikawa, S., Okano, H. & Miura, M., 1998 4月 23, In: Journal of Cell Science. 111, 6, p. 667-673 7 p.

研究成果: Article › 査読

25 被引用数 (Scopus)

Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cells

Pincus, D. W., Keyoung, H. M., Harrison-Restelli, C., Goodman, R. R., Fraser, R. A. R., Edgar, M., Sakakibara, S. I., Okano, H., Nedergaard, M. & Goldman, S. A., 1998 5月, In: Annals of Neurology. 43, 5, p. 576-585 10 p.

研究成果: Article › 査読

117 被引用数 (Scopus)

Inositol 1,4,5-trisphosphate receptor mediates ventralising signals in Xenopus embryos

Kume, S., Muto, A., Okano, H. & Mikoshiba, K., 1998 12月 1, In: Zygote. 6, 1 SUPPL., p. S145-S146

研究成果: Article › 査読

Localization of 5-HT2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken

Hamada, S., Senzaki, K., Hamaguchi-Hamada, K., Tabuchi, K., Yamamoto, H., Yamamoto, T., Yoshikawa, S., Okano, H. & Okado, N., 1998 3月 1, In: Molecular Brain Research. 54, 2, p. 199-211 13 p.

研究成果: Article › 査読

104 被引用数 (Scopus)

Mammalian BarH homologue is a potential regulator of neural bHLH genes

Saito, T., Sawamoto, K., Okano, H., Anderson, D. J. & Mikoshiba, K., 1998 7月 15, In: Developmental Biology. 199, 2, p. 216-225 10 p.

研究成果: Article › 査読

48 被引用数 (Scopus)

The human Musashi homolog 1 (MSI1) gene encoding the homologue of Musashi/Nrp-1, a neural RNA-binding protein putatively expressed in CNS stem cells and neural progenitor cells

Good, P., Yoda, A., Sakakibara, S. I., Yamamoto, A., Imai, T., Sawa, H., Ikeuchi, T., Tsuji, S., Satoh, H. & Okano, H., 1998 9月 15, In: Genomics. 52, 3, p. 382-384 3 p.

研究成果: Article › 査読

50 被引用数 (Scopus)

1999

A genetic approach to visualization neurotechnique of multisynaptic neural pathways using plant lectin transgene

Yoshihara, Y., Mizuno, T., Nakahira, M., Kawasaki, M., Watanabe, Y., Kagamiyama, H., Jishage, K. I., Ueda, O., Suzuki, H., Tabuchi, K., Sawamoto, K., Okano, H., Noda, T. & Mori, K., 1999 1月, In: Neuron. 22, 1, p. 33-41 9 p.

研究成果: Article › 査読

92 被引用数 (Scopus)

Caspase activity is required for nephrogenesis in the developing mouse metanephros

Araki, T., Saruta, T., Okano, H. & Miura, M., 1999 5月 1, In: Experimental Cell Research. 248, 2, p. 423-429 7 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

Cloning and characterization of Dfak56, a homolog of focal adhesion kinase, in Drosophila melanogaster

Fujimoto, J., Sawamoto, K., Okabe, M., Takagi, Y., Tezuka, T., Yoshikawa, S., Ryo, H., Okano, H. & Yamamoto, T., 1999 10月 8, In: Journal of Biological Chemistry. 274, 41, p. 29196-29201 6 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator

Kanuka, H., Sawamoto, K., Inohara, N., Matsuno, K., Okano, H. & Miura, M., 1999 11月, In: Molecular Cell. 4, 5, p. 757-769 13 p.

研究成果: Article › 査読

Open Access

62 被引用数 (Scopus)

Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development

Sawamoto, K., Yamada, C., Kishida, S., Hirota, Y., Taguchi, A., Kikuchi, A. & Okano, H., 1999 3月 18, In: Oncogene. 18, 11, p. 1967-1974 8 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

Involvement of caspases in cytotoxic cytokine-mediated oligodendrocyte cell death

Miura, M., Hisahara, S., Takano, R., Shoji, S. & Okano, H., 1999, In: Protoplasma. 206, 4, p. 219-223 5 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems

Akamatsu, W., Okano, H. J., Osumi, N., Inoue, T., Nakamura, S., Sakakibara, S. I., Miura, M., Matsuo, N., Darnell, R. B. & Okano, H., 1999 8月 17, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 17, p. 9885-9890 6 p.

研究成果: Article › 査読

211 被引用数 (Scopus)

Musashi and Seven in absentia downregulate Tramtrack through distinct mechanisms in Drosophila eye development

Hirota, Y., Okabe, M., Imai, T., Kurusu, M., Yamamoto, A., Miyao, S., Nakamura, M., Sawamoto, K. & Okano, H., 1999 9月 1, In: Mechanisms of Development. 87, 1-2, p. 93-101 9 p.

研究成果: Article › 査読

36 被引用数 (Scopus)

Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: Implicated mechanisms for caspase activation

Kanuka, H., Hisahara, S., Sawamoto, K., Shoji, S. I., Okano, H. & Miura, M., 1999 1月 5, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 1, p. 145-150 6 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Stimulation of myelin basic protein gene transcription by fyn tyrosine kinase for myelination

Umemori, H., Kadowaki, Y., Hirosawa, K., Yoshida, Y., Hironaka, K., Okano, H. & Yamamoto, T., 1999 2月 15, In: Journal of Neuroscience. 19, 4, p. 1393-1397 5 p.

研究成果: Article › 査読

Open Access

41 被引用数 (Scopus)

Structure, backbone dynamics and interactions with RNA of the C-terminal RNA-binding domain of a mouse neural RNA-binding protein, Musashi1

Nagata, T., Kanno, R., Kurihara, Y., Uesugi, S., Imai, T., Sakakibara, S. I., Okano, H. & Katahira, M., 1999 3月 26, In: Journal of Molecular Biology. 287, 2, p. 315-330 16 p.

研究成果: Article › 査読

31 被引用数 (Scopus)

The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH₂-terminal kinase pathway

Sawamoto, K., Winge, P., Koyama, S., Hirota, Y., Yamada, C., Miyao, S., Yoshikawa, S., Jin, M. H., Kikuchi, A. & Okano, H., 1999 7月 26, In: Journal of Cell Biology. 146, 2, p. 361-372 12 p.

研究成果: Article › 査読

23 被引用数 (Scopus)

WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans

Rocheleau, C. E., Yasuda, J., Tae Ho Shin, H. S., Lin, R., Sawa, H., Okano, H., Priess, J. R., Davis, R. J. & Mello, C. C., 1999, In: Cell. 97, 6, p. 717-726 10 p.

研究成果: Article › 査読

219 被引用数 (Scopus)

2000

Caspases determine the vulnerability of oligodendrocytes in the ischemic brain

Shibata, M., Hisahara, S., Hara, H., Yamawaki, T., Fukuuchi, Y., Yuan, J., Okano, H. & Miura, M., 2000 9月, In: Journal of Clinical Investigation. 106, 5, p. 643-653 11 p.

研究成果: Article › 査読

Open Access

78 被引用数 (Scopus)

Components of the SWI/SNF complex are required for asymmetric cell division in C. elegans

Sawa, H., Kouike, H. & Okano, H., 2000, In: Molecular Cell. 6, 3, p. 617-624 8 p.

研究成果: Article › 査読

Open Access

78 被引用数 (Scopus)

Dissection of signaling cascades through gp130 in vivo: Reciprocal roles for STAT3- and SHP2-mediated signals in immune responses

Ohtani, T., Ishihara, K., Atsumi, T., Nishida, K., Kaneko, Y., Miyata, T., Itoh, S., Narimatsu, M., Maeda, H., Fukada, T., Itoh, M., Okano, H., Hibi, M. & Hirano, T., 2000 1月, In: Immunity. 12, 1, p. 95-105 11 p.

研究成果: Article › 査読

Open Access

124 被引用数 (Scopus)

Drob-1, a Drosophila member of the Bcl-2/CED-9 family that promotes cell death

Igaki, T., Kanuka, H., Inohara, N., Sawamoto, K., Núñez, G., Okano, H. & Miura, M., 2000 1月 18, In: Proceedings of the National Academy of Sciences of the United States of America. 97, 2, p. 662-667 6 p.

研究成果: Article › 査読

37 被引用数 (Scopus)

Expression patterns of musashi homologs of the ascidians, Halocynthia roretzi and Ciona intestinalis

Kawashima, T., Murakami, A. R., Ogasawara, M., Tanaka, K. J., Isoda, R., Sasakura, Y., Nishikata, T., Okano, H. & Makabe, K. W., 2000, In: Development Genes and Evolution. 210, 3, p. 162-165 4 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

GAL4/UAS-WGA system as a powerful tool for tracing Drosophila transsynaptic neural pathways

Tabuchi, K., Sawamoto, K., Suzuki, E., Ozaki, K., Sone, M., Hama, C., Tanifuji-Morimoto, T., Yuasa, Y., Yoshihara, Y., Nose, A. & Okano, H., 2000 1月 1, In: Journal of neuroscience research. 59, 1, p. 94-99 6 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus

Roy, N. S., Wang, S., Jiang, L., Kang, J., Benraiss, A., Harrison-Restelli, C., Fraser, R. A. R., Couldwell, W. T., Kawaguchi, A., Okano, H., Nedergaard, M. & Goldman, S. A., 2000 3月, In: Nature medicine. 6, 3, p. 271-277 7 p.

研究成果: Article › 査読

170 被引用数 (Scopus)

Learning and memory

Okano, H., Hirano, T. & Balaban, E., 2000 11月 7, In: Proceedings of the National Academy of Sciences of the United States of America. 97, 23, p. 12403-12404 2 p.

研究成果: Article › 査読

Open Access

58 被引用数 (Scopus)

MSI-1, a neural RNA-binding protein, is involved in male mating behaviour in Caenorhabditis elegans

Yoda, A., Sawa, H. & Okano, H., 2000, In: Genes to Cells. 5, 11, p. 885-895 11 p.

研究成果: Article › 査読

38 被引用数 (Scopus)

Musashi1: An evolutionally conserved marker for CNS progenitor cells including neural stem cells

Kaneko, Y., Sakakibara, S., Imai, T., Suzuki, A., Nakamura, Y., Sawamoto, K., Ogawa, Y., Toyama, Y., Miyata, T. & Okano, H., 2000 2月, In: Developmental Neuroscience. 22, 1-2, p. 139-153 15 p.

研究成果: Article › 査読

449 被引用数 (Scopus)

Mutations modulating the Argos-regulated signaling pathway in Drosophila eye development

Taguchi, A., Sawamoto, K. & Okano, H., 2000 4月 1, In: Genetics. 154, 4, p. 1639-1648 10 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Nerve growth factor protects oligodendrocytes from tumor necrosis factor-α-induced injury through Akt-mediated signaling mechanisms

Takano, R., Hisahara, S., Namikawa, K., Kiyama, H., Okano, H. & Miurat, M., 2000 5月 26, In: Journal of Biological Chemistry. 275, 21, p. 16360-16365 6 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

Promoter-targeted selection and isolation of neural progenitor cells from the adult human ventricular zone

Roy, N. S., Benraiss, A., Wang, S., Fraser, R. A. R., Goodman, R., Couldwell, W. T., Nedergaard, M., Kawaguchi, A., Okano, H. & Goldman, S. A., 2000 2月 1, In: Journal of neuroscience research. 59, 3, p. 321-331 11 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

Role of caspase-1 subfamily in cytotoxic cytokine-induced oligodendrocyte cell death

Hisahara, S., Takano, R., Shoji, S., Okano, H. & Miura, M., 2000 1月 1, In: Journal of Neural Transmission, Supplement. 58, p. 135-142 8 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

Targeted expression of baculovirus p35 caspase inhibitor in oligodendrocytes protects mice against autoimmune-mediated demyelination

Hisahara, S., Araki, T., Sugiyama, F., Yagami, K. I., Suzuki, M., Abe, K., Yamamura, K. I., Miyazaki, J. I., Momoi, T., Saruta, T., Bernard, C. C. A., Okano, H. & Miura, M., 2000 2月 1, In: EMBO Journal. 19, 3, p. 341-348 8 p.

研究成果: Article › 査読

96 被引用数 (Scopus)

The bHLH gene Hes1 as a repressor of the neuronal commitment of CNS stem cells

Nakamura, Y., Sakakibara, S. I., Miyata, T., Ogawa, M., Shimazaki, T., Weiss, S., Kageyama, R. & Okano, H., 2000 1月 1, In: Journal of Neuroscience. 20, 1, p. 283-293 11 p.

研究成果: Article › 査読

Open Access

174 被引用数 (Scopus)

The C. elegans septin genes, unc-59 and unc-61, are required for normal postembryonic cytokineses and morphogenesis but have no essential function in embryogenesis

Nguyen, T. Q., Sawa, H., Okano, H. & White, J. G., 2000, In: Journal of Cell Science. 113, 21, p. 3825-3837 13 p.

研究成果: Article › 査読

107 被引用数 (Scopus)

The interaction between the Drosophila secreted protein Argos and the epidermal growth factor receptor inhibits dimerization of the receptor and binding of secreted spitz to the receptor

Jin, M. H., Sawamoto, K., Ito, M. & Okano, H., 2000 3月, In: Molecular and cellular biology. 20, 6, p. 2098-2107 10 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

2001

Activation of murine cytomegalovirus immediate-early promoter in cerebral ventricular zone and glial progenitor cells in transgenic mice

Li, R. Y., Baba, S., Kosugi, I., Arai, Y., Kawasaki, H., Shinmura, Y., Sakakibara, S. I., Okano, H. & Tsutsui, Y., 2001, In: Glia. 35, 1, p. 41-52 12 p.

研究成果: Article › 査読

20 被引用数 (Scopus)

Asymmetric inheritance of radial glial fibers by cortical neurons

Miyata, T., Kawaguchi, A., Okano, H. & Ogawa, M., 2001 9月 13, In: Neuron. 31, 5, p. 727-741 15 p.

研究成果: Article › 査読

732 被引用数 (Scopus)

Brain from bone: Efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent

Kohyama, J., Abe, H., Shimazaki, T., Koizumi, A., Nakashima, K., Gojo, S., Taga, T., Okano, H., Hata, J. I. & Umezawa, A., 2001 10月, In: Differentiation. 68, 4-5, p. 235-244 10 p.

研究成果: Article › 査読

99 被引用数 (Scopus)

Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination

Hisahara, S., Yuan, J., Momoi, T., Okano, H. & Miura, M., 2001 1月 1, In: Journal of Experimental Medicine. 193, 1, p. 111-122 12 p.

研究成果: Article › 査読

42 被引用数 (Scopus)

Critical role of Caenorhabditis elegans homologs of Cds1 (Chk2)-related kinases in meiotic recombination

Oishi, I., Iwai, K., Kagohashi, Y., Fujimoto, H., Kariya, K. I., Kataoka, T., Sawa, H., Okano, H., Otani, H., Yamamura, H. & Minami, Y., 2001, In: Molecular and cellular biology. 21, 4, p. 1329-1335 7 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Direct isolation of committed neuronal progenitor cells from transgenic mice coexpressing spectrally distinct fluorescent protemins regulated by stage-specific neural promoters

Sawamoto, K., Yamamoto, A., Kawaguchi, A., Yamaguchi, M., Mori, K., Goldman, S. A. & Okano, H., 2001 8月 1, In: Journal of neuroscience research. 65, 3, p. 220-227 8 p.

研究成果: Article › 査読

59 被引用数 (Scopus)

Expression of mouse igf2 mRNA-binding protein 3 and its implications for the developing central nervous system

Mori, H., Sakakibara, S. I., Imai, T., Nakamura, Y., Iijima, T., Suzuki, A., Yuasa, Y., Takeda, M. & Okano, H., 2001 4月 15, In: Journal of neuroscience research. 64, 2, p. 132-143 12 p.

研究成果: Article › 査読

47 被引用数 (Scopus)

Expression of the neural RNA- binding protein Musashi1 in human gliomas

Toda, M., Iizuka, Y., Yu, W., Imai, T., Ikeda, E., Yoshida, K., Kawase, T., Kawakami, Y., Okano, H. & Uyemura, K., 2001, In: Glia. 34, 1, p. 1-7 7 p.

研究成果: Article › 査読

141 被引用数 (Scopus)

Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene

Sawamoto, K., Nakao, N., Kakishita, K., Ogawa, Y., Toyama, Y., Yamamoto, A., Yamaguchi, M., Mori, K., Goldman, S. A., Itakura, T. & Okano, H., 2001 6月 1, In: Journal of Neuroscience. 21, 11, p. 3895-3903 9 p.

研究成果: Article › 査読

Open Access

188 被引用数 (Scopus)

Genetic and functional analysis of PARP, a DNA strand break-binding enzyme

Uchida, M., Hanai, S., Uematsu, N., Sawamoto, K., Okano, H., Miwa, M. & Uchida, K., 2001 6月 2, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 477, 1-2, p. 89-96 8 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain

Keyoung, H. M., Roy, N. S., Benraiss, A., Louissaint, A., Suzuki, A., Hashimoto, M., Rashbaum, W. K., Okano, H. & Goldman, S. A., 2001, In: Nature Biotechnology. 19, 9, p. 843-850 8 p.

研究成果: Article › 査読

42 被引用数 (Scopus)

Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis

Kishi, N., Tang, Z., Maeda, Y., Hirai, A., Mo, R., Ito, M., Suzuki, S., Nakao, K., Kinoshita, T., Kadesch, T., Hui, C. C., Artavanis-Tsakonas, S., Okano, H. & Matsuno, K., 2001 2月 1, In: International Journal of Developmental Neuroscience. 19, 1, p. 21-35 15 p.

研究成果: Article › 査読

78 被引用数 (Scopus)

岡野 栄之

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岡野栄之