Hideyuki Okano

2005

Functional properties of dopaminergic neurones in the mouse olfactory bulb

Pignatelli, A., Kobayashi, K., Okano, H. & Belluzzi, O., 2005 4月 15, In: Journal of Physiology. 564, 2, p. 501-514 14 p.

研究成果: Article › 査読

Open Access

82 被引用数 (Scopus)

Gain-of-function screen identifies a role of the Sec61α translocon in Drosophila postmitotic neurotoxicity

Kanuka, H., Hiratou, T., Igaki, T., Kanda, H., Kuranaga, E., Sawamoto, K., Aigaki, T., Okano, H. & Miura, M., 2005 11月 30, In: Biochimica et Biophysica Acta - General Subjects. 1726, 3, p. 225-237 13 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine

Suzuki, K., Fukui, H., Kayahara, T., Sawada, M., Seno, H., Hiai, H., Kageyama, R., Okano, H. & Chiba, T., 2005 3月 4, In: Biochemical and Biophysical Research Communications. 328, 1, p. 348-352 5 p.

研究成果: Article › 査読

64 被引用数 (Scopus)

Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA

Iijima, T., Imai, T., Kimura, Y., Bernstein, A., Okano, H. J., Yuzaki, M. & Okano, H., 2005 11月 22, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 47, p. 17190-17195 6 p.

研究成果: Article › 査読

23 被引用数 (Scopus)

Identification of neural stem cells in adult human brain: Its implication in the strategy for repairing the damaged central nervous system

Okano, H., 2005 11月 1, In: Clinical Neurology. 45, 11, p. 871-873 3 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Increased number of neural progenitors in human temporal lobe epilepsy

Crespel, A., Rigau, V., Coubes, P., Rousset, M. C., De Bock, F., Okano, H., Baldy-Moulinier, M., Bockaert, J. & Lerner-Natoli, M., 2005 8月, In: Neurobiology of Disease. 19, 3, p. 436-450 15 p.

研究成果: Article › 査読

57 被引用数 (Scopus)

Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine

Matsumoto, T., Okamoto, R., Yajima, T., Mori, T., Okamoto, S., Ikeda, Y., Mukai, M., Yamazaki, M., Oshima, S., Tsuchiya, K., Nakamura, T., Kanai, T., Okano, H., Inazawa, J., Hibi, T. & Watanabe, M., 2005 6月, In: Gastroenterology. 128, 7, p. 1851-1867 17 p.

研究成果: Article › 査読

Open Access

72 被引用数 (Scopus)

Inhibition of glioma cell proliferation by neural stem cell factor

Suzuki, T., Izumoto, S., Wada, K., Fujimoto, Y., Maruno, M., Yamasaki, M., Kanemura, Y., Shimazaki, T., Okano, H. & Yoshimine, T., 2005 9月, In: Journal of Neuro-Oncology. 74, 3, p. 233-239 7 p.

研究成果: Article › 査読

21 被引用数 (Scopus)

In vitro screening of exogenous factors for human neural stem/progenitor cell proliferation using measurement of total ATP content in viable cells

Kanemura, Y., Mori, H., Nakagawa, A., Islam, M. O., Kodama, E., Yamamoto, A., Shofuda, T., Kobayashi, S., Miyake, J., Yamazaki, T., Hirano, S. I., Yamasaki, M. & Okano, H., 2005, In: Cell Transplantation. 14, 9, p. 673-682 10 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

In vivo imaging of engrafted neural stem cells: Its application in evaluating the optimal timing of transplantation for spinal cord injury

Okada, S., Ishii, K., Yamane, J., Iwanami, A., Ikegami, T., Katoh, H., Iwamoto, Y., Nakamura, M., Miyoshi, H., Okano, H. J., Contag, C. H., Toyama, Y. & Okano, H., 2005 11月, In: FASEB Journal. 19, 13, p. 1839-1841 3 p.

研究成果: Article › 査読

194 被引用数 (Scopus)

In vivo PET measurements with [¹¹C]PE2I to evaluate fetal mesencephalic transplantations to unilateral 6-OHDA-lesioned rats

Inaji, M., Yoshizaki, T., Okauchi, T., Maeda, J., Nagai, Y., Nariai, T., Ohno, K., Ando, K., Okano, H., Obayashi, S. & Suhara, T., 2005, In: Cell Transplantation. 14, 9, p. 655-663 9 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation

Yano, M., Okano, H. J. & Okano, H., 2005 4月 1, In: Journal of Biological Chemistry. 280, 13, p. 12690-12699 10 p.

研究成果: Article › 査読

61 被引用数 (Scopus)

Lecithinized brain-derived neurotrophic factor promotes the differentiation of embryonic stem cells in vitro and in vivo

Kitagawa, A., Nakayama, T., Takenaga, M., Matsumoto, K., Tokura, Y., Ohta, Y., Ichinohe, M., Yamaguchi, Y., Suzuki, N., Okano, H. & Igarashi, R., 2005 3月 25, In: Biochemical and Biophysical Research Communications. 328, 4, p. 1051-1057 7 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16

Hishikawa, K., Marumo, T., Miura, S., Nakanishi, A., Matsuzaki, Y., Shibata, K., Kohike, H., Komori, T., Hayashi, M., Nakaki, T., Nakauchi, H., Okano, H. & Fujita, T., 2005 3月 4, In: Biochemical and Biophysical Research Communications. 328, 1, p. 288-291 4 p.

研究成果: Article › 査読

22 被引用数 (Scopus)

Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice

Sakatani, T., Kaneda, A., Iacobuzio-Donahue, C. A., Carter, M. G., De Boom Witzel, S., Okano, H., Ko, M. S. H., Ohlsson, R., Longo, D. L. & Feinberg, A. P., 2005 3月 25, In: Science. 307, 5717, p. 1976-1978 3 p.

研究成果: Article › 査読

284 被引用数 (Scopus)

Musculin/MyoR is expressed in kidney side population cells and can regulate their function

Hishikawa, K., Marumo, T., Miura, S., Nakanishi, A., Matsuzaki, Y., Shibata, K., Ichiyanagi, T., Kohike, H., Komori, T., Takahashi, I., Takase, O., Imai, N., Yoshikawa, M., Inowa, T., Hayashi, M., Nakaki, T., Nakauchi, H., Okano, H. & Fujita, T., 2005 6月, In: Journal of Cell Biology. 169, 6, p. 921-928 8 p.

研究成果: Article › 査読

73 被引用数 (Scopus)

Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in rats: Possible involvement of Nedd9 in the differentiation of neurons after ischemia

Sasaki, T., Iwata, S., Okano, H. J., Urasaki, Y., Hamada, J., Tanaka, H., Dang, N. H., Okano, H. & Morimoto, C., 2005 11月, In: Stroke. 36, 11, p. 2457-2462 6 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

Neural stem cells and regeneration of injured spinal cord

Okano, H., Okada, S., Nakamura, M. & Toyama, Y., 2005 11月, In: Kidney international. 68, 5, p. 1927-1931 5 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Notch signaling functions as a binary switch for the determination of glandular and luminal fates of endodermal epithelium during chicken stomach development

Matsuda, Y., Wakamatsu, Y., Kohyama, J., Okano, H., Fukuda, K. & Yasugi, S., 2005 6月, In: Development. 132, 12, p. 2783-2793 11 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

Possibility for neurogenesis in substantia nigra of parkinsonian brain

Yoshimi, K., Ren, Y. R., Seki, T., Yamada, M., Ooizumi, H., Onodera, M., Saito, Y., Murayama, S., Okano, H., Mizuno, Y. & Mochizuki, H., 2005 7月 1, In: Annals of Neurology. 58, 1, p. 31-40 10 p.

研究成果: Article › 査読

125 被引用数 (Scopus)

Potential functional neural repair with grafted neural stem cells of early embryonic neuroepithelial origin

Uchida, K., Momiyama, T., Okano, H., Yuzaki, M., Koizumi, A., Mine, Y. & Kawase, T., 2005 7月, In: Neuroscience Research. 52, 3, p. 276-286 11 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

Prospective characterization of neural stem cells by flow cytometry analysis using a combination of surface markers

Nagato, M., Heike, T., Kato, T., Yamanaka, Y., Yoshimoto, M., Shimazaki, T., Okano, H. & Nakahata, T., 2005 5月 15, In: Journal of neuroscience research. 80, 4, p. 456-466 11 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

Regenerative medicine for the central nervous system - Transplantation of neural stem cells into the injured spinal cord -

Kaneko, S., Nakamura, M., Ogawa, Y., Watanabe, K., Iwanami, A., Toyama, Y. & Okano, H., 2005 2月 1, In: Japan Medical Association Journal. 48, 2, p. 68-80 13 p.

研究成果: Article › 査読

Targeted expression of anti-apoptotic protein p35 in oligodendrocytes reduces delayed demyelination and functional impairment after spinal cord injury

Tamura, M., Nakamura, M., Ogawa, Y., Toyama, Y., Miura, M. & Okano, H., 2005 9月 1, In: Glia. 51, 4, p. 312-321 10 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

The RNA-binding protein HuD regulates neuronal cell identity and maturation

Akamatsu, W., Fujihara, H., Mitsuhashi, T., Yano, M., Shibata, S., Hayakawa, Y., Okano, H. J., Sakakibara, S. I., Takano, H., Takano, T., Takahashi, T., Noda, T. & Okano, H., 2005 3月 22, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 12, p. 4625-4630 6 p.

研究成果: Article › 査読

147 被引用数 (Scopus)

The transmembrane protein, Tincar, is involved in the development of the compound eye in Drosophila melanogaster

Hirota, Y., Sawamoto, K., Takahashi, K., Ueda, R. & Okano, H., 2005 2月, In: Development Genes and Evolution. 215, 2, p. 90-96 7 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells

Yuasa, S., Itabashi, Y., Koshimizu, U., Tanaka, T., Sugimura, K., Kinoshita, M., Hattori, F., Fukami, S. I., Shimazaki, T., Okano, H., Ogawa, S. & Fukuda, K., 2005, In: Nature Biotechnology. 23, 5, p. 607-611 5 p.

研究成果: Article › 査読

259 被引用数 (Scopus)

Transplantation of embryonic spinal cord-derived neurospheres support growth of supraspinal projections and functional recovery after spinal cord injury in the neonatal rat

Nakamura, M., Okano, H., Toyama, Y., Dai, H. N., Finn, T. P. & Bregman, B. S., 2005 8月 15, In: Journal of neuroscience research. 81, 4, p. 457-468 12 p.

研究成果: Article › 査読

50 被引用数 (Scopus)

Transplantation of human neural stem cells for spinal cord injury in primates

Iwanami, A., Kaneko, S., Nakamura, M., Kanemura, Y., Mori, H., Kobayashi, S., Yamasaki, M., Momoshima, S., Ishii, H., Ando, K., Tanioka, Y., Tamaoki, N., Nomura, T., Toyama, Y. & Okano, H., 2005 4月 15, In: Journal of neuroscience research. 80, 2, p. 182-190 9 p.

研究成果: Article › 査読

318 被引用数 (Scopus)

Transplantation of neural stem cells for spinal cord injury

Nakamura, M., Toyama, Y. & Okano, H., 2005 11月 1, In: Clinical Neurology. 45, 11, p. 874-876 3 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Use of TH-EGFP transgenic mice as a source of identified dopaminergic neurons for physiological studies in postnatal cell culture

Jomphe, C., Bourque, M. J., Fortin, G. D., St-Gelais, F., Okano, H., Kobayashi, K. & Trudeau, L. E., 2005 7月 15, In: Journal of Neuroscience Methods. 146, 1, p. 1-12 12 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

Visualization of spatiotemporal activation of Notch signaling: Live monitoring and significance in neural development

Kohyama, J., Tokunaga, A., Fujita, Y., Miyoshi, H., Nagai, T., Miyawaki, A., Nakao, K., Matsuzaki, Y. & Okano, H., 2005 10月 1, In: Developmental Biology. 286, 1, p. 311-325 15 p.

研究成果: Article › 査読

52 被引用数 (Scopus)

2006

A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells

Sakaguchi, M., Shingo, T., Shimazaki, T., Okano, H. J., Shiwa, M., Ishibashi, S., Oguro, H., Ninomiya, M., Kadoya, T., Horie, H., Shibuya, A., Mizusawa, H., Poirier, F., Nakauchi, H., Sawamoto, K. & Okano, H., 2006 5月 2, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 18, p. 7112-7117 6 p.

研究成果: Article › 査読

145 被引用数 (Scopus)

Administration of hematopoietic cytokines in the subacute phase after cerebral infarction is effective for functional recovery facilitating proliferation of intrinsic neural stem/progenitor cells and transition of bone marrow-derived neuronal cells

Kawada, H., Takizawa, S., Takanashi, T., Morita, Y., Fujita, J., Fukuda, K., Takagi, S., Okano, H., Ando, K. & Hotta, T., 2006 2月, In: Circulation. 113, 5, p. 701-710 10 p.

研究成果: Article › 査読

113 被引用数 (Scopus)

A practical device for pinpoint delivery of molecules into multiple neurons in culture

Hara, C., Tateyama, K., Akamatsu, N., Imabayashi, H., Karaki, K., Nomura, N., Okano, H. & Miyawaki, A., 2006 12月, In: Brain Cell Biology. 35, 4-6, p. 229-237 9 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord

Kaneko, S., Iwanami, A., Nakamura, M., Kishino, A., Kikuchi, K., Shibata, S., Okano, H. J., Ikegami, T., Moriya, A., Konishi, O., Nakayama, C., Kumagai, K., Kimura, T., Sato, Y., Goshima, Y., Taniguchi, M., Ito, M., He, Z., Toyama, Y. & Okano, H., 2006 12月, In: Nature medicine. 12, 12, p. 1380-1389 10 p.

研究成果: Article › 査読

267 被引用数 (Scopus)

Bcl2 enhances survival of newborn neurons in the normal and ischemic hippocampus

Sasaki, T., Kitagawa, K., Yagita, Y., Sugiura, S., Omura-Matsuoka, E., Tanaka, S., Matsushita, K., Okano, H., Tsujitnoto, Y. & Hori, M., 2006 11月 1, In: Journal of neuroscience research. 84, 6, p. 1187-1196 10 p.

研究成果: Article › 査読

60 被引用数 (Scopus)

Bidirectional regulation of dopamine D2 and neurotensin NTS1 receptors in dopamine neurons

Jomphe, C., Lemelin, P. L., Okano, H., Kobayashi, K. & Trudeau, L. E., 2006 12月, In: European Journal of Neuroscience. 24, 10, p. 2789-2800 12 p.

研究成果: Article › 査読

40 被引用数 (Scopus)

Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury

Okada, S., Nakamura, M., Katoh, H., Miyao, T., Shimazaki, T., Ishii, K., Yamane, J., Yoshimura, A., Iwamoto, Y., Toyama, Y. & Okano, H., 2006 7月, In: Nature medicine. 12, 7, p. 829-834 6 p.

研究成果: Article › 査読

731 被引用数 (Scopus)

Disease progression of human SOD1 (G93A) transgenic ALS model rats

Matsumoto, A., Okada, Y., Nakamichi, M., Nakamura, M., Toyama, Y., Sobue, G., Nagai, M., Aoki, M., Itoyama, Y. & Okano, H., 2006 1月 1, In: Journal of neuroscience research. 83, 1, p. 119-133 15 p.

研究成果: Article › 査読

77 被引用数 (Scopus)

Distinct functions of human numb isoforms revealed by misexpression in the neural stem cell lineage in the Drosophila larval brain

Toriya, M., Tokunaga, A., Sawamoto, K., Nakao, K. & Okano, H., 2006 2月, In: Developmental Neuroscience. 28, 1-2, p. 142-155 14 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain

Rawal, N., Castelo-Branco, G., Sousa, K. M., Kele, J., Kobayashi, K., Okano, H. & Arenas, E., 2006 5月 15, In: Experimental Cell Research. 312, 9, p. 1626-1636 11 p.

研究成果: Article › 査読

42 被引用数 (Scopus)

Effect of neurosphere size on the growth rate of human neural stem/progenitor cells

Mori, H., Ninomiya, K., Kino-Oka, M., Shofuda, T., Islam, M. O., Yamasaki, M., Okano, H., Taya, M. & Kanemura, Y., 2006 12月, In: Journal of neuroscience research. 84, 8, p. 1682-1691 10 p.

研究成果: Article › 査読

105 被引用数 (Scopus)

Enhanced neurogenesis in the ischemic striatum following EGF-induced expansion of transit-amplifying cells in the subventricular zone

Ninomiya, M., Yamashita, T., Araki, N., Okano, H. & Sawamoto, K., 2006 7月 31, In: Neuroscience Letters. 403, 1-2, p. 63-67 5 p.

研究成果: Article › 査読

58 被引用数 (Scopus)

Enhanced therapeutic efficacy of G207 for the treatment of glioma through Musashi1 promoter retargeting of γ34.5-mediated virulence

Kanai, R., Tomita, H., Shinoda, A., Takahashi, M., Goldman, S., Okano, H., Kawase, T. & Yazaki, T., 2006 1月, In: Gene Therapy. 13, 2, p. 106-116 11 p.

研究成果: Article › 査読

25 被引用数 (Scopus)

Enhanced therapeutic efficacy of oncolytic herpes vector G207 against human non-small cell lung cancer - Expression of an RNA-binding protein, Musashi1, as a marker for the tailored gene therapy

Kanai, R., Eguchi, K., Takahashi, M., Goldman, S., Okano, H., Kawase, T. & Yazaki, T., 2006 11月 1, In: Journal of Gene Medicine. 8, 11, p. 1329-1340 12 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

Expression of Musashi-1 in the rat stomach and changes during mucosal injury and restitution

Nagata, H., Akiba, Y., Suzuki, H., Okano, H. & Hibi, T., 2006 1月 9, In: FEBS Letters. 580, 1, p. 27-33 7 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

Expression of RNA-binding protein Musashi in hair follicle development and hair cycle progression

Sugiyama-Nakagiri, Y., Akiyama, M., Shibata, S., Okano, H. & Shimizu, H., 2006 1月, In: American Journal of Pathology. 168, 1, p. 80-92 13 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

Histopathological and behavioral improvement of murine mucopolysaccharidosis type VII by intracerebral transplantation of neural stem cells

Fukuhara, Y., Li, X. K., Kitazawa, Y., Inagaki, M., Matsuoka, K., Kosuga, M., Kosaki, R., Shimazaki, T., Endo, H., Umezawa, A., Okano, H., Takahashi, T. & Okuyama, T., 2006 3月, In: Molecular Therapy. 13, 3, p. 548-555 8 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Implication of "Down syndrome cell adhesion molecule" in the hippocampal neurogenesis of ischemic monkeys

Yamashima, T., Popivanova, B. K., Guo, J., Kotani, S., Wakayama, T., Iseki, S., Sawamoto, K., Okano, H., Fujii, C., Mukaida, N. & Tonchev, A. B., 2006, In: Hippocampus. 16, 11, p. 924-935 12 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

岡野 栄之

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岡野栄之