Hideyuki Okano

Article

Disease progression of human SOD1 (G93A) transgenic ALS model rats

Matsumoto, A., Okada, Y., Nakamichi, M., Nakamura, M., Toyama, Y., Sobue, G., Nagai, M., Aoki, M., Itoyama, Y. & Okano, H., 2006 1月 1, In: Journal of neuroscience research. 83, 1, p. 119-133 15 p.

研究成果: Article › 査読

73 被引用数 (Scopus)

Disorders in myelination in the twitcher mutant: Immunohistochemical and biochemical studies

Mikoshiba, K., Fujishiro, M., Kohsaka, S., Okano, H., Takamatsu, K. & Tsukada, Y., 1985 8月, In: Neurochemical Research. 10, 8, p. 1129-1141 13 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity

Tsuboi, D., Kuroda, K., Tanaka, M., Namba, T., Iizuka, Y., Taya, S., Shinoda, T., Hikita, T., Muraoka, S., Iizuka, M., Nimura, A., Mizoguchi, A., Shiina, N., Sokabe, M., Okano, H., Mikoshiba, K. & Kaibuchi, K., 2015 4月 28, In: Nature Neuroscience. 18, 5, p. 698-707 10 p.

研究成果: Article › 査読

44 被引用数 (Scopus)

Dissection of signaling cascades through gp130 in vivo: Reciprocal roles for STAT3- and SHP2-mediated signals in immune responses

Ohtani, T., Ishihara, K., Atsumi, T., Nishida, K., Kaneko, Y., Miyata, T., Itoh, S., Narimatsu, M., Maeda, H., Fukada, T., Itoh, M., Okano, H., Hibi, M. & Hirano, T., 2000 1月, In: Immunity. 12, 1, p. 95-105 11 p.

研究成果: Article › 査読

Open Access

194 被引用数 (Scopus)

Distinct expression pattern of a deafness gene, KIAA1199, in a primate Cochlea

Hosoya, M., Fujioka, M., Okano, H. & Ogawa, K., 2016, In: BioMed Research International. 2016, 1781894.

研究成果: Article › 査読

12 被引用数 (Scopus)

Distinct Expression Patterns of Causative Genes Responsible for Hereditary Progressive Hearing Loss in Non-Human Primate Cochlea

Hosoya, M., Fujioka, M., Ogawa, K. & Okano, H., 2016 2月 26, In: Scientific reports. 6, 22250.

研究成果: Article › 査読

33 被引用数 (Scopus)

Distinct expression patterns of splicing isoforms of mNumb in the endocrine lineage of developing pancreas

Yoshida, T., Tokunaga, A., Nakao, K. & Okano, H., 2003 10月, In: Differentiation. 71, 8, p. 486-495 10 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

Distinct functions of human numb isoforms revealed by misexpression in the neural stem cell lineage in the Drosophila larval brain

Toriya, M., Tokunaga, A., Sawamoto, K., Nakao, K. & Okano, H., 2006 2月 1, In: Developmental Neuroscience. 28, 1-2, p. 142-155 14 p.

研究成果: Article › 査読

32 被引用数 (Scopus)

Distinct roles of endogenous vascular endothelial factor receptor 1 and 2 in neural protection after spinal cord injury

Shinozaki, M., Nakamura, M., Konomi, T., Kobayashi, Y., Takano, M., Saito, N., Toyama, Y. & Okano, H., 2014 1月, In: Neuroscience Research. 78, 1, p. 55-64 10 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Distribution of tight junctions in the primate cochlear lateral wall

Saeki, T., Hosoya, M., Shibata, S., Okano, H., Fujioka, M. & Ogawa, K., 2020 1月 19, In: Neuroscience Letters. 717, 134686.

研究成果: Article › 査読

2 被引用数 (Scopus)

DN-cadherin is required for spatial arrangement of nerve terminals and ultrastructural organization of synapses

Iwai, Y., Hirota, Y., Ozaki, K., Okano, H., Takeichi, M. & Uemura, T., 2002, In: Molecular and Cellular Neuroscience. 19, 3, p. 375-388 14 p.

研究成果: Article › 査読

60 被引用数 (Scopus)

Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium

Hirata, A., Utikal, J., Yamashita, S., Aoki, H., Watanabe, A., Yamamoto, T., Okano, H., Bardeesy, N., Kunisada, T., Ushijima, T., Hara, A., Jaenisch, R., Hochedlinger, K. & Yamada, Y., 2013 1月 1, In: Development (Cambridge). 140, 1, p. 66-75 10 p.

研究成果: Article › 査読

54 被引用数 (Scopus)

Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction

Suda, Y., Kuzumaki, N., Sone, T., Narita, M., Tanaka, K., Hamada, Y., Iwasawa, C., Shibasaki, M., Maekawa, A., Matsuo, M., Akamatsu, W., Hattori, N., Okano, H. & Narita, M., 2018 2月 20, In: Molecular brain. 11, 1, 6.

研究成果: Article › 査読

Open Access

29 被引用数 (Scopus)

Downregulation of Notch mediates the seamless transition of individual Drosophila neuroepithelial progenitors into optic medullar neuroblasts during prolonged G1

Orihara-Ono, M., Toriya, M., Nakao, K. & Okano, H., 2011 3月 1, In: Developmental Biology. 351, 1, p. 163-175 13 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina

Ozawa, Y., Nakao, K., Shimazaki, T., Takeda, J., Akira, S., Ishihara, K., Hirano, T., Oguchi, Y. & Okano, H., 2004 6月, In: Molecular and Cellular Neuroscience. 26, 2, p. 258-270 13 p.

研究成果: Article › 査読

42 被引用数 (Scopus)

Dramatic improvement in genome assembly achieved using doubled-haploid genomes

Zhang, H., Tan, E., Suzuki, Y., Hirose, Y., Kinoshita, S., Okano, H., Kudoh, J., Shimizu, A., Saito, K., Watabe, S. & Asakawa, S., 2014 10月 27, In: Scientific reports. 4, 6780.

研究成果: Article › 査読

16 被引用数 (Scopus)

Drob-1, a Drosophila member of the Bcl-2/CED-9 family that promotes cell death

Igaki, T., Kanuka, H., Inohara, N., Sawamoto, K., Núñez, G., Okano, H. & Miura, M., 2000 1月 18, In: Proceedings of the National Academy of Sciences of the United States of America. 97, 2, p. 662-667 6 p.

研究成果: Article › 査読

132 被引用数 (Scopus)

Drosophila big brain does not act as a water channel, but mediates cell adhesion

Tatsumi, K., Tsuji, S., Miwa, H., Morisaku, T., Nuriya, M., Orihara, M., Kaneko, K., Okano, H. & Yasui, M., 2009 6月 18, In: FEBS Letters. 583, 12, p. 2077-2082 6 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

Drosophila caspase transduces Shaggy/GSK-3β kinase activity in neural precursor development

Kanuka, H., Kuranaga, E., Takemoto, K., Hiratou, T., Okano, H. & Miura, M., 2005 11月 2, In: EMBO Journal. 24, 21, p. 3793-3806 14 p.

研究成果: Article › 査読

81 被引用数 (Scopus)

Drosophila deltex mediates suppressor of hairless-independent and late-endosomal activation of notch signaling

Hori, K., Fostier, M., Ito, M., Fuwa, T. J., Go, M. J., Okano, H., Baron, M. & Matsuno, K., 2004 11月, In: Development. 131, 22, p. 5527-5537 11 p.

研究成果: Article › 査読

156 被引用数 (Scopus)

Dual usage of a stage-specific fluorescent reporter system based on a helper-dependent adenoviral vector to visualize osteogenic differentiation

Sone, T., Shin, M., Ouchi, T., Sasanuma, H., Miyamoto, A., Ohte, S., Tsukamoto, S., Nakanishi, M., Okano, H., Katagiri, T. & Mitani, K., 2019 12月 1, In: Scientific reports. 9, 1, 9705.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Dynamic regulation of innate immune responses in Drosophila by Senju-mediated glycosylation

Yamamoto-Hino, M., Muraoka, M., Kondo, S., Ueda, R., Okano, H. & Goto, S., 2015 5月 5, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 18, p. 5809-5814 6 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Dynamic spatiotemporal expression changes in connexins of the developing primate’s cochlea

Hosoya, M., Fujioka, M., Murayama, A. Y., Ogawa, K., Okano, H. & Ozawa, H., 2021 7月, In: Genes. 12, 7, 1082.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain

Rawal, N., Castelo-Branco, G., Sousa, K. M., Kele, J., Kobayashi, K., Okano, H. & Arenas, E., 2006 5月 15, In: Experimental Cell Research. 312, 9, p. 1626-1636 11 p.

研究成果: Article › 査読

41 被引用数 (Scopus)

Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice

Asada, N., Takase, M., Nakamura, J., Oguchi, A., Asada, M., Suzuki, N., Yamamura, K. I., Nagoshi, N., Shibata, S., Rao, T. N., Fehling, H. J., Fukatsu, A., Minegishi, N., Kita, T., Kimura, T., Okano, H., Yamamoto, M. & Yanagita, M., 2011 10月 3, In: Journal of Clinical Investigation. 121, 10, p. 3981-3990 10 p.

研究成果: Article › 査読

254 被引用数 (Scopus)

Dysfunction of ventrolateral striatal dopamine receptor type 2-expressing medium spiny neurons impairs instrumental motivation

Tsutsui-Kimura, I., Takiue, H., Yoshida, K., Xu, M., Yano, R., Ohta, H., Nishida, H., Bouchekioua, Y., Okano, H., Uchigashima, M., Watanabe, M., Takata, N., Drew, M. R., Sano, H., Mimura, M. & Tanaka, K. F., 2017 2月 1, In: Nature communications. 8, 14304.

研究成果: Article › 査読

27 被引用数 (Scopus)

Dysmyelination in transgenic mice resulting from expression of class I histocompatibility molecules in oligodendrocytes

Turnley, A. M., Morahan, G., Okano, H., Bernard, O., Mikoshiba, K., Allison, J., Bartlett, P. F. & Miller, J. F. A. P., 1991, In: Nature. 353, 6344, p. 566-569 4 p.

研究成果: Article › 査読

105 被引用数 (Scopus)

Early development of the cochlea of the common marmoset, a non-human primate model

Hosoya, M., Fujioka, M., Okahara, J., Yoshimatsu, S., Okano, H. & Ozawa, H., 2022 12月, In: Neural Development. 17, 1, 6.

研究成果: Article › 査読

Open Access

Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development

Sawamoto, K., Yamada, C., Kishida, S., Hirota, Y., Taguchi, A., Kikuchi, A. & Okano, H., 1999 3月 18, In: Oncogene. 18, 11, p. 1967-1974 8 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

Effect of ADAM28 on carcinoma cell metastasis by cleavage of von willebrand factor

Mochizuki, S., Soejima, K., Shimoda, M., Abe, H., Sasaki, A., Okano, H. J., Okano, H. & Okada, Y., 2012 6月 20, In: Journal of the National Cancer Institute. 104, 12, p. 906-922 17 p.

研究成果: Article › 査読

76 被引用数 (Scopus)

Effect of neurosphere size on the growth rate of human neural stem/progenitor cells

Mori, H., Ninomiya, K., Kino-Oka, M., Shofuda, T., Islam, M. O., Yamasaki, M., Okano, H., Taya, M. & Kanemura, Y., 2006 12月, In: Journal of neuroscience research. 84, 8, p. 1682-1691 10 p.

研究成果: Article › 査読

102 被引用数 (Scopus)

Effect of-opioid receptor agonist on the growth of non-small cell lung cancer (NSCLC) cells

Kuzumaki, N., Suzuki, A., Narita, M., Hosoya, T., Nagasawa, A., Imai, S., Yamamizu, K., Morita, H., Nagase, H., Okada, Y., Okano, H. J., Yamashita, J. K., Okano, H., Suzuki, T. & Narita, M., 2012 3月 13, In: British Journal of Cancer. 106, 6, p. 1148-1152 5 p.

研究成果: Article › 査読

23 被引用数 (Scopus)

Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men

Irie, J., Inagaki, E., Fujita, M., Nakaya, H., Mitsuishi, M., Yamaguchi, S., Yamashita, K., Shigaki, S., Ono, T., Yukioka, H., Okano, H., Nabeshima, Y. I., Imai, S. I., Yasui, M., Tsubota, K. & Itoh, H., 2020, In: Endocrine journal. 67, 2, p. 153-160 8 p.

研究成果: Article › 査読

Open Access

55 被引用数 (Scopus)

Effects of an electric field on sleep quality and life span mediated by ultraviolet (UV)-A/blue light photoreceptor CRYPTOCHROME in Drosophila

Kawasaki, H., Okano, H., Nedachi, T., Nakagawa-Yagi, Y., Hara, A. & Ishida, N., 2021 12月, In: Scientific reports. 11, 1, 20543.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Efficient Derivation of Multipotent Neural Stem/Progenitor Cells from Non-Human Primate Embryonic Stem Cells

Shimada, H., Okada, Y., Ibata, K., Ebise, H., Ota, S. I., Tomioka, I., Nomura, T., Maeda, T., Kouda, K., Yuzaki, M., Sasaki, E., Nakamura, M. & Okano, H., 2012 11月 14, In: PloS one. 7, 11, e49469.

研究成果: Article › 査読

24 被引用数 (Scopus)

Efficient generation of Knock-in/Knock-out marmoset embryo via CRISPR/Cas9 gene editing

Kumita, W., Sato, K., Suzuki, Y., Kurotaki, Y., Harada, T., Zhou, Y., Kishi, N., Sato, K., Aiba, A., Sakakibara, Y., Feng, G., Okano, H. & Sasaki, E., 2019 12月 1, In: Scientific reports. 9, 1, 12719.

研究成果: Article › 査読

Open Access

26 被引用数 (Scopus)

Efficient generation of mature cerebellar Purkinje cells from mouse embryonic stem cells

Tao, O., Shimazaki, T., Okada, Y., Naka, H., Kohda, K., Yuzaki, M., Mizusawa, H. & Okano, H., 2010 2月 1, In: Journal of neuroscience research. 88, 2, p. 234-247 14 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons

Suzuki, S., Akamatsu, W., Kisa, F., Sone, T., Ishikawa, K. I., Kuzumaki, N., Katayama, H., Miyawaki, A., Hattori, N. & Okano, H., 2017 1月 29, In: Biochemical and Biophysical Research Communications. 483, 1, p. 88-93 6 p.

研究成果: Article › 査読

41 被引用数 (Scopus)

Elavl3 is essential for the maintenance of Purkinje neuron axons

Ogawa, Y., Kakumoto, K., Yoshida, T., Kuwako, K. I., Miyazaki, T., Yamaguchi, J., Konno, A., Hata, J., Uchiyama, Y., Hirai, H., Watanabe, M., Darnell, R. B., Okano, H. & Okano, H. J., 2018 12月 1, In: Scientific reports. 8, 1, 2722.

研究成果: Article › 査読

Open Access

22 被引用数 (Scopus)

Electrical stimulation modulates fate determination of differentiating embryonic stem cells

Yamada, M., Tanemura, K., Okada, S., Iwanami, A., Nakamura, M., Mizuno, H., Ozawa, M., Ohyama-Goto, R., Kitamura, N., Kawano, M., Tan-Takeuchi, K., Ohtsuka, C., Miyawaki, A., Takashima, A., Ogawa, M., Toyama, Y., Okano, H. & Kondo, T., 2007 3月, In: Stem Cells. 25, 3, p. 562-570 9 p.

研究成果: Article › 査読

146 被引用数 (Scopus)

Elucidation of developmental patterns of marmoset corpus callosum through a comparative MRI in marmosets, chimpanzees, and humans

Sakai, T., Komaki, Y., Hata, J., Okahara, J., Okahara, N., Inoue, T., Mikami, A., Matsui, M., Oishi, K., Sasaki, E. & Okano, H., 2017 9月, In: Neuroscience Research. 122, p. 25-34 10 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression

Ieda, M., Fukuda, K., Hisaka, Y., Kimura, K., Kawaguchi, H., Fujita, J., Shimoda, K., Takeshita, E., Okano, H., Kurihara, Y., Kurihara, H., Ishida, J., Fukamizu, A., Federoff, H. J. & Ogawa, S., 2004 3月, In: Journal of Clinical Investigation. 113, 6, p. 876-884 9 p.

研究成果: Article › 査読

105 被引用数 (Scopus)

Engrafted Neural Stem/Progenitor Cells Promote Functional Recovery through Synapse Reorganization with Spared Host Neurons after Spinal Cord Injury

Yokota, K., Kobayakawa, K., Kubota, K., Miyawaki, A., Okano, H., Ohkawa, Y., Iwamoto, Y. & Okada, S., 2015, In: Stem cell reports. 5, 2, p. 264-277 14 p.

研究成果: Article › 査読

Open Access

39 被引用数 (Scopus)

Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice

Takeda, H., Hosoya, M., Fujioka, M., Saegusa, C., Saeki, T., Miwa, T., Okano, H. & Minoda, R., 2018 12月 1, In: Scientific reports. 8, 1, 1941.

研究成果: Article › 査読

14 被引用数 (Scopus)

Enhanced aggregation of androgen receptor in induced pluripotent stem cell-derived neurons from spinal and bulbar muscular atrophy

Nihei, Y., Ito, D., Okada, Y., Akamatsu, W., Yagi, T., Yoshizaki, T., Okano, H. & Suzuki, N., 2013 3月 22, In: Journal of Biological Chemistry. 288, 12, p. 8043-8052 10 p.

研究成果: Article › 査読

38 被引用数 (Scopus)

Enhanced angiogenesis in grafted skins by laser-induced stress wave-assisted gene transfer of hepatocyte growth factor

Terakawa, M., Sato, S., Saitoh, D., Tsuda, H., Ashida, H., Okano, H. & Obara, M., 2007 5月, In: Journal of Biomedical Optics. 12, 3, 034031.

研究成果: Article › 査読

22 被引用数 (Scopus)

Enhanced Functional Recovery from Spinal Cord Injury in Aged Mice after Stem Cell Transplantation through HGF Induction

Takano, M., Kawabata, S., Shibata, S., Yasuda, A., Nori, S., Tsuji, O., Nagoshi, N., Iwanami, A., Ebise, H., Horiuchi, K., Okano, H. & Nakamura, M., 2017 3月 14, In: Stem cell reports. 8, 3, p. 509-518 10 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

Enhanced neurogenesis in the ischemic striatum following EGF-induced expansion of transit-amplifying cells in the subventricular zone

Ninomiya, M., Yamashita, T., Araki, N., Okano, H. & Sawamoto, K., 2006 7月 31, In: Neuroscience Letters. 403, 1-2, p. 63-67 5 p.

研究成果: Article › 査読

55 被引用数 (Scopus)

Enhanced proliferation of progenitor cells in the subventricular zone and limited neuronal production in the striatum and neocortex of adult macaque monkeys after global cerebral ischemia

Tonchev, A. B., Yamashima, T., Sawamoto, K. & Okano, H., 2005 9月 15, In: Journal of neuroscience research. 81, 6, p. 776-788 13 p.

研究成果: Article › 査読

103 被引用数 (Scopus)

Enhanced therapeutic efficacy of G207 for the treatment of glioma through Musashi1 promoter retargeting of γ34.5-mediated virulence

Kanai, R., Tomita, H., Shinoda, A., Takahashi, M., Goldman, S., Okano, H., Kawase, T. & Yazaki, T., 2006 1月, In: Gene Therapy. 13, 2, p. 106-116 11 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

岡野 栄之

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岡野栄之