Hideyuki Okano

Article

Involvement of ferroptosis in human motor neuron cell death

Matsuo, T., Adachi-Tominari, K., Sano, O., Kamei, T., Nogami, M., Ogi, K., Okano, H. & Yano, M., 2021 8月 20, In: Biochemical and Biophysical Research Communications. 566, p. 24-29 6 p.

研究成果: Article › 査読

Open Access

4 被引用数 (Scopus)

Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation

Yano, M., Okano, H. J. & Okano, H., 2005 4月 1, In: Journal of Biological Chemistry. 280, 13, p. 12690-12699 10 p.

研究成果: Article › 査読

104 被引用数 (Scopus)

Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling

Kase, Y., Otsu, K., Shimazaki, T. & Okano, H., 2019 6月 11, In: Stem cell reports. 12, 6, p. 1313-1328 16 p.

研究成果: Article › 査読

Open Access

24 被引用数 (Scopus)

Involvement of the septo-hippocampal cholinergic pathway in association with septal acetylcholinesterase upregulation in a mouse model of tauopathy

Hara, Y., Motoi, Y., Hikishima, K., Mizuma, H., Onoe, H., Matsumoto, S. E., Elahi, M., Okano, H., Aoki, S. & Hattori, N., 2017 1月 1, In: Current Alzheimer Research. 14, 1, p. 94-103 10 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

IPS cell technologies: Significance and applications to CNS regeneration and disease

Okano, H. & Yamanaka, S., 2014 3月 31, In: Molecular brain. 7, 1, 22.

研究成果: Article › 査読

169 被引用数 (Scopus)

Isolation and characterization of dendritic cells from common marmosets for preclinical cell therapy studies

Ohta, S., Ueda, Y., Yaguchi, M., Matsuzaki, Y., Nakamura, M., Toyama, Y., Tanioka, Y., Tamaoki, N., Nomura, T., Okano, H., Kawakami, Y. & Toda, M., 2008 4月, In: Immunology. 123, 4, p. 566-574 9 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Isolation and characterization of neural crest-like progenitor cells in human umbilical cord blood

Al-Bakri, Z., Ishige-Wada, M., Fukuda, N., Yoshida-Noro, C., Nagoshi, N., Okano, H., Mugishima, H. & Matsumoto, T., 2020 12月, In: Regenerative Therapy. 15, p. 53-63 11 p.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero

Kubota, Y., Takubo, K., Hirashima, M., Nagoshi, N., Kishi, K., Okuno, Y., Nakamura-Ishizu, A., Sano, K., Murakami, M., Ema, M., Omatsu, Y., Takahashi, S., Nagasawa, T., Shibuya, M., Okano, H. & Suda, T., 2011 5月, In: Journal of Experimental Medicine. 208, 5, p. 949-960 12 p.

研究成果: Article › 査読

31 被引用数 (Scopus)

Isolation and identification of putative stem/progenitor cells from human cycling endometrium

Okano, H., 2007 9月 1, In: Journal of Obstetrics and Gynaecology Research. 33, SUPPL.1, p. S56-S57

研究成果: Article › 査読

Isolation and transplantation of dopaminergic neurons and neural stem cells

Okano, H., Yoshizaki, T., Shimazaki, T. & Sawamoto, K., 2002 10月 1, In: Parkinsonism and Related Disorders. 9, 1, p. 23-28 6 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells

Yoshizaki, T., Inaji, M., Kouike, H., Shimazaki, T., Sawamoto, K., Ando, K., Date, I., Kobayashi, K., Suhara, T., Uchiyama, Y. & Okano, H., 2004 6月 3, In: Neuroscience Letters. 363, 1, p. 33-37 5 p.

研究成果: Article › 査読

75 被引用数 (Scopus)

Isolation of a Drosophila Gene Encoding a Head‐Specific Guanylyl Cyclase

Yoshikawa, S., Miyamoto, I., Aruga, J., Furuichi, T., Okano, H. & Mikoshiba, K., 1993 4月, In: Journal of Neurochemistry. 60, 4, p. 1570-1573 4 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

Isolation of mouse mesenchymal stem cells on the basis of expression of Sca-1 and PDGFR-α

Houlihan, D. D., Mabuchi, Y., Morikawa, S., Niibe, K., Araki, D., Suzuki, S., Okano, H. & Matsuzaki, Y., 2012 12月, In: Nature Protocols. 7, 12, p. 2103-2111 9 p.

研究成果: Article › 査読

184 被引用数 (Scopus)

Isolation of multipotent neural crest-derived stem cells from the adult mouse cornea

Yoshida, S., Shimmura, S., Nagoshi, N., Fukuda, K., Matsuzaki, Y., Okano, H. & Tsubota, K., 2006 12月, In: Stem Cells. 24, 12, p. 2714-2722 9 p.

研究成果: Article › 査読

153 被引用数 (Scopus)

JMJD1C exhibits multiple functions in epigenetic regulation during spermatogenesis

Nakajima, R., Okano, H. & Noce, T., 2016 9月, In: PloS one. 11, 9, e163466.

研究成果: Article › 査読

9 被引用数 (Scopus)

Kidney Specific Protein-Positive Cells Derived from Embryonic Stem Cells Reproduce Tubular Structures In Vitro and Differentiate into Renal Tubular Cells

Morizane, R., Monkawa, T., Fujii, S., Yamaguchi, S., Homma, K., Matsuzaki, Y., Okano, H. & Itoh, H., 2013 6月 3, In: PloS one. 8, 6, e64843.

研究成果: Article › 査読

36 被引用数 (Scopus)

Large-area fluorescence and electron microscopic correlative imaging with multibeam scanning electron microscopy

Shibata, S., Iseda, T., Mitsuhashi, T., Oka, A., Shindo, T., Moritoki, N., Nagai, T., Otsubo, S., Inoue, T., Sasaki, E., Akazawa, C., Takahashi, T., Schalek, R., Lichtman, J. W. & Okano, H., 2019 4月 24, In: Frontiers in Neural Circuits. 13, 29.

研究成果: Article › 査読

Open Access

7 被引用数 (Scopus)

Laser-induced stress wave-assisted gene transfection with cationic liposome

Terakawa, M., Otsuka, R., Sato, S., Satoh, Y., Takishima, K., Ashida, H., Okano, H. & Obara, M., 2007 12月 14, In: Japanese Journal of Applied Physics, Part 2: Letters. 46, 45-49, p. L1243-L1245

研究成果: Article › 査読

3 被引用数 (Scopus)

Learning and memory

Okano, H., Hirano, T. & Balaban, E., 2000 11月 7, In: Proceedings of the National Academy of Sciences of the United States of America. 97, 23, p. 12403-12404 2 p.

研究成果: Article › 査読

61 被引用数 (Scopus)

Lecithinized brain-derived neurotrophic factor promotes the differentiation of embryonic stem cells in vitro and in vivo

Kitagawa, A., Nakayama, T., Takenaga, M., Matsumoto, K., Tokura, Y., Ohta, Y., Ichinohe, M., Yamaguchi, Y., Suzuki, N., Okano, H. & Igarashi, R., 2005 3月 25, In: Biochemical and Biophysical Research Communications. 328, 4, p. 1051-1057 7 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Lecithinized superoxide dismutase (PC-SOD) improved spinal cord injury-induced motor dysfunction through suppression of oxidative stress and enhancement of neurotrophic factor production

Takenaga, M., Ohta, Y., Tokura, Y., Hamaguchi, A., Nakamura, M., Okano, H. & Igarashi, R., 2006 1月 10, In: Journal of Controlled Release. 110, 2, p. 283-289 7 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

Leptin suppresses ghrelin-induced activation of neuropeptide Y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway

Kohno, D., Nakata, M., Maekawa, F., Fujiwara, K., Maejima, Y., Kuramochi, M., Shimazaki, T., Okano, H., Onaka, T. & Yada, T., 2007 5月, In: Endocrinology. 148, 5, p. 2251-2263 13 p.

研究成果: Article › 査読

114 被引用数 (Scopus)

Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16

Hishikawa, K., Marumo, T., Miura, S., Nakanishi, A., Matsuzaki, Y., Shibata, K., Kohike, H., Komori, T., Hayashi, M., Nakaki, T., Nakauchi, H., Okano, H. & Fujita, T., 2005 3月 4, In: Biochemical and Biophysical Research Communications. 328, 1, p. 288-291 4 p.

研究成果: Article › 査読

22 被引用数 (Scopus)

LIM homeobox 8 (Lhx8) is a key regulator of the cholinergic neuronal function via a tropomyosin receptor kinase A (TrkA)-mediated positive feedback loop

Tomioka, T., Shimazaki, T., Yamauchi, T., Oki, T., Ohgoh, M. & Okano, H., 2014 1月 10, In: Journal of Biological Chemistry. 289, 2, p. 1000-1010 11 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

LNGFR⁺THY-1⁺ human pluripotent stem cell-derived neural crest-like cells have the potential to develop into mesenchymal stem cells

Ouchi, T., Morikawa, S., Shibata, S., Fukuda, K., Okuno, H., Fujimura, T., Kuroda, T., Ohyama, M., Akamatsu, W., Nakagawa, T. & Okano, H., 2016 12月 1, In: Differentiation. 92, 5, p. 270-280 11 p.

研究成果: Article › 査読

Open Access

14 被引用数 (Scopus)

LNGFR⁺THY-1⁺VCAM-1^hi+ cells reveal functionally distinct subpopulations in mesenchymal stem cells

Mabuchi, Y., Morikawa, S., Harada, S., Niibe, K., Suzuki, S., Renault-Mihara, F., Houlihan, D. D., Akazawa, C., Okano, H. & Matsuzaki, Y., 2013, In: Stem cell reports. 1, 2, p. 152-165 14 p.

研究成果: Article › 査読

128 被引用数 (Scopus)

Localization of 5-HT2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken

Hamada, S., Senzaki, K., Hamaguchi-Hamada, K., Tabuchi, K., Yamamoto, H., Yamamoto, T., Yoshikawa, S., Okano, H. & Okado, N., 1998 3月 1, In: Molecular Brain Research. 54, 2, p. 199-211 13 p.

研究成果: Article › 査読

103 被引用数 (Scopus)

Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: Oncogenic transformation with epithelial-mesenchymal transition

Nori, S., Okada, Y., Nishimura, S., Sasaki, T., Itakura, G., Kobayashi, Y., Renault-Mihara, F., Shimizu, A., Koya, I., Yoshida, R., Kudoh, J., Koike, M., Uchiyama, Y., Ikeda, E., Toyama, Y., Nakamura, M. & Okano, H., 2015 3月 10, In: Stem cell reports. 4, 3, p. 360-373 14 p.

研究成果: Article › 査読

138 被引用数 (Scopus)

Long-term selective stimulation of transplanted neural stem/progenitor cells for spinal cord injury improves locomotor function

Kawai, M., Imaizumi, K., Ishikawa, M., Shibata, S., Shinozaki, M., Shibata, T., Hashimoto, S., Kitagawa, T., Ago, K., Kajikawa, K., Shibata, R., Kamata, Y., Ushiba, J., Koga, K., Furue, H., Matsumoto, M., Nakamura, M., Nagoshi, N. & Okano, H., 2021 11月 23, In: Cell Reports. 37, 8, 110019.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice

Sakatani, T., Kaneda, A., Iacobuzio-Donahue, C. A., Carter, M. G., De Boom Witzel, S., Okano, H., Ko, M. S. H., Ohlsson, R., Longo, D. L. & Feinberg, A. P., 2005 3月 25, In: Science. 307, 5717, p. 1976-1978 3 p.

研究成果: Article › 査読

282 被引用数 (Scopus)

LOTUS inhibits neuronal apoptosis and promotes tract regeneration in contusive spinal cord injury model mice

Ito, S., Nagoshi, N., Tsuji, O., Shibata, S., Shinozaki, M., Kawabata, S., Kojima, K., Yasutake, K., Hirokawa, T., Matsumoto, M., Takei, K., Nakamura, M. & Okano, H., 2018 9月 1, In: eNeuro. 5, 5, e0303.

研究成果: Article › 査読

16 被引用数 (Scopus)

LOTUS overexpression via ex vivo gene transduction further promotes recovery of motor function following human iPSC-NS/PC transplantation for contusive spinal cord injury

Ito, S., Nagoshi, N., Kamata, Y., Kojima, K., Nori, S., Matsumoto, M., Takei, K., Nakamura, M. & Okano, H., 2021 11月 9, In: Stem cell reports. 16, 11, p. 2703-2717 15 p.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Low-dose rapamycin-induced autophagy in cochlear outer sulcus cells

Saegusa, C., Hosoya, M., Nishiyama, T., Saeki, T., Fujimoto, C., Okano, H., Fujioka, M. & Ogawa, K., 2020 6月 1, In: Laryngoscope investigative otolaryngology. 5, 3, p. 520-528 9 p.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Low immunogenicity of mouse induced pluripotent stem cell-derived neural stem/progenitor cells

Itakura, G., Ozaki, M., Nagoshi, N., Kawabata, S., Nishiyama, Y., Sugai, K., Iida, T., Kashiwagi, R., Ookubo, T., Yastake, K., Matsubayashi, K., Kohyama, J., Iwanami, A., Matsumoto, M., Nakamura, M. & Okano, H., 2017 12月 1, In: Scientific reports. 7, 1, 12996.

研究成果: Article › 査読

13 被引用数 (Scopus)

Macrophage migration inhibitory factor (MIF) promotes cell survival and proliferation of neural stem/progenitor cells

Ota, S., Misawa, A., Fukaya, R., Inoue, S., Kanemura, Y., Okano, H., Kawakami, Y. & Toda, M., 2012 10月 1, In: Development (Cambridge). 139, 19

研究成果: Article › 査読

69 被引用数 (Scopus)

Making and repairing the mammalian brain: Introduction.

Okano, H., 2003 6月, In: Seminars in cell & developmental biology. 14, 3, 1 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Mammalian BarH homologue is a potential regulator of neural bHLH genes

Saito, T., Sawamoto, K., Okano, H., Anderson, D. J. & Mikoshiba, K., 1998 7月 15, In: Developmental Biology. 199, 2, p. 216-225 10 p.

研究成果: Article › 査読

48 被引用数 (Scopus)

Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems

Akamatsu, W., Okano, H. J., Osumi, N., Inoue, T., Nakamura, S., Sakakibara, S. I., Miura, M., Matsuo, N., Darnell, R. B. & Okano, H., 1999 8月 17, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 17, p. 9885-9890 6 p.

研究成果: Article › 査読

205 被引用数 (Scopus)

Mapping of Notch activation during cochlear development in mice: Implications for determination of prosensory domain and cell fate diversification

Murata, J., Tokunaga, A., Okano, H. & Kubo, T., 2006 7月 20, In: Journal of Comparative Neurology. 497, 3, p. 502-518 17 p.

研究成果: Article › 査読

56 被引用数 (Scopus)

Mapping orbitofrontal-limbic maturation in non-human primates: A longitudinal magnetic resonance imaging study

Uematsu, A., Hata, J., Komaki, Y., Seki, F., Yamada, C., Okahara, N., Kurotaki, Y., Sasaki, E. & Okano, H., 2017 12月, In: NeuroImage. 163, p. 55-67 13 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain

Tokunaga, A., Kohyama, J., Yoshida, T., Nakao, K., Sawamoto, K. & Okano, H., 2004 7月, In: Journal of Neurochemistry. 90, 1, p. 142-154 13 p.

研究成果: Article › 査読

89 被引用数 (Scopus)

Markerless analysis of hindlimb kinematics in spinal cord-injured mice through deep learning

Sato, Y., Kondo, T., Shinozaki, M., Shibata, R., Nagoshi, N., Ushiba, J., Nakamura, M. & Okano, H., 2022 3月, In: Neuroscience Research. 176, p. 49-56 8 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Mature adipocyte-derived cells, dedifferentiated fat cells (DFAT), promoted functional recovery from spinal cord injury-induced motor dysfunction in rats

Ohta, Y., Takenaga, M., Tokura, Y., Hamaguchi, A., Matsuraoto, T., Kano, K., Mugishima, H., Okano, H. & Igarashi, R., 2008, In: Cell Transplantation. 17, 8, p. 877-886 10 p.

研究成果: Article › 査読

66 被引用数 (Scopus)

Measurement of baseline locomotion and other behavioral traits in a common marmoset model of Parkinson's disease established by a single administration regimen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: providing reference data for efficacious preclinical evaluations

Ando, K., Inoue, T., Hikishima, K., Komaki, Y., Kawai, K., Inoue, R., Nishime, C., Nishinaka, E., Urano, K. & Okano, H., 2020, In: Behavioural pharmacology. 31, 1, p. 45-60 16 p.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling

Nakashima, H., Tsujimura, K., Irie, K., Imamura, T., Trujillo, C. A., Ishizu, M., Uesaka, M., Pan, M., Noguchi, H., Okada, K., Aoyagi, K., Andoh-Noda, T., Okano, H., Muotri, A. R. & Nakashima, K., 2021 5月 18, In: Cell Reports. 35, 7, 109124.

研究成果: Article › 査読

Open Access

5 被引用数 (Scopus)

MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model

Ogawa, Y., Morikawa, S., Okano, H., Mabuchi, Y., Suzuki, S., Yaguchi, T., Sato, Y., Mukai, S., Yaguchi, S., Inaba, T., Okamoto, S., Kawakami, Y., Tsubota, K., Matsuzaki, Y. & Shimmura, S., 2016 1月 26, In: eLife. 5, JANUARY2016, e09394.

研究成果: Article › 査読

24 被引用数 (Scopus)

MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells

Tsuyama, J., Bunt, J., Richards, L. J., Iwanari, H., Mochizuki, Y., Hamakubo, T., Shimazaki, T. & Okano, H., 2015 9月 8, In: Stem cell reports. 5, 3, p. 365-377 13 p.

研究成果: Article › 査読

Open Access

34 被引用数 (Scopus)

MIF maintains the tumorigenic capacity of brain tumor-initiating cells by directly inhibiting p53

Fukaya, R., Ohta, S., Yaguchi, T., Matsuzaki, Y., Sugihara, E., Okano, H., Saya, H., Kawakami, Y., Kawase, T., Yoshida, K. & Toda, M., 2016 5月 1, In: Cancer Research. 76, 9, p. 2813-2823 11 p.

研究成果: Article › 査読

Open Access

40 被引用数 (Scopus)

Migration and differentiation of transplanted enteric neural crest-derived cells in murine model of Hirschsprung’s disease

Nishikawa, R., Hotta, R., Shimojima, N., Shibata, S., Nagoshi, N., Nakamura, M., Matsuzaki, Y., Okano, H. J., Kuroda, T., Okano, H. & Morikawa, Y., 2015 8月 23, In: Cytotechnology. 67, 4, p. 661-670 10 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Mimicking the neurotrophic factor profile of embryonic spinal cord controls the differentiation potential of spinal progenitors into neuronal cells

Nakamura, M., Tsuji, O., Bregman, B. S., Toyama, Y. & Okano, H., 2011, In: PloS one. 6, 6, e20717.

研究成果: Article › 査読

8 被引用数 (Scopus)

岡野 栄之

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岡野栄之