• 6860 引用
  • 41 h指数
1991 …2019

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 6860 引用
  • 41 h指数
  • 130 Article
  • 5 Review article
  • 2 Comment/debate
  • 1 Letter
2019

Features of and preventive measures against hypertension in the young

Kawabe, H., Azegami, T., Takeda, A., Kanda, T., Saito, I., Saruta, T. & Hirose, H., 2019 1 1, : : Hypertension Research.

研究成果: Review article

公開
6 引用 (Scopus)
3 引用 (Scopus)
2018

Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21

Tanikawa, C., Kamatani, Y., Toyoshima, O., Sakamoto, H., Ito, H., Takahashi, A., Momozawa, Y., Hirata, M., Fuse, N., Takai-Igarashi, T., Shimizu, A., Sasaki, M., Yamaji, T., Sawada, N., Iwasaki, M., Tsugane, S., Naito, M., Hishida, A., Wakai, K., Furusyo, N. および13人, Murakami, Y., Nakamura, Y., Imoto, I., Inazawa, J., Oze, I., Sato, N., Tanioka, F., Sugimura, H., Hirose, H., Yoshida, T., Matsuo, K., Kubo, M. & Matsuda, K., 2018 12, : : Cancer science. 109, 12, p. 4015-4024 10 p.

研究成果: Article

7 引用 (Scopus)

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Demenais, F., Margaritte-Jeannin, P., Barnes, K. C., Cookson, W. O. C., Altmüller, J., Ang, W., Barr, R. G., Beaty, T. H., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E. および155人, Burkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., Couto Alves, A., Curtin, J. A., Custovic, A., Daley, D., De Jongste, J. C., Del-Rio-Navarro, B. E., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Freidin, M. B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Granell, R., Graves, P. E., Gudbjartsson, D. F., Haahtela, T., Heckbert, S. R., Heederik, D., Heinrich, J., Heliövaara, M., Henderson, J., Himes, B. E., Hirose, H., Hirschhorn, J. N., Hofman, A., Holt, P., Hottenga, J., Hudson, T. J., Hui, J., Imboden, M., Ivanov, V., Jaddoe, V. W. V., James, A., Janson, C., Jarvelin, M. R., Jarvis, D., Jones, G., Jonsdottir, I., Jousilahti, P., Kabesch, M., Kähönen, M., Kantor, D. B., Karunas, A. S., Khusnutdinova, E., Koppelman, G. H., Kozyrskyj, A. L., Kreiner, E., Kubo, M., Kumar, R., Kumar, A., Kuokkanen, M., Lahousse, L., Laitinen, T., Laprise, C., Lathrop, M., Lau, S., Lee, Y. A., Lehtimäki, T., Letort, S., Levin, A. M., Li, G., Liang, L., Loehr, L. R., London, S. J., Loth, D. W., Manichaikul, A., Marenholz, I., Martinez, F. J., Matheson, M. C., Mathias, R. A., Matsumoto, K., Mbarek, H., McArdle, W. L., Melbye, M., Melén, E., Meyers, D., Michel, S., Mohamdi, H., Musk, A. W., Myers, R. A., Nieuwenhuis, M. A. E., Noguchi, E., O'Connor, G. T., Ogorodova, L. M., Palmer, C. D., Palotie, A., Park, J. E., Pennell, C. E., Pershagen, G., Polonikov, A., Postma, D. S., Probst-Hensch, N., Puzyrev, V. P., Raby, B. A., Raitakari, O. T., Ramasamy, A., Rich, S. S., Robertson, C. F., Romieu, I., Salam, M. T., Salomaa, V., Schlünssen, V., Scott, R., Selivanova, P. A., Sigsgaard, T., Simpson, A., Siroux, V., Smith, L. J., Solodilova, M., Standl, M., Stefansson, K., Strachan, D. P., Stricker, B. H., Takahashi, A., Thompson, P. J., Thorleifsson, G., Thorsteinsdottir, U., Tiesler, C. M. T., Torgerson, D. G., Tsunoda, T., Uitterlinden, A. G., Van Der Valk, R. J. P., Vaysse, A., Vedantam, S., Von Berg, A., Von Mutius, E., Vonk, J. M., Waage, J., Wareham, N. J., Weiss, S. T., White, W. B., Wickman, M., Widén, E., Willemsen, G., Williams, L. K., Wouters, I. M., Yang, J. J., Zhao, J. H., Moffatt, M. F., Ober, C. & Nicolae, D. L., 2018 1 1, : : Nature genetics. 50, 1, p. 42-50 9 p.

研究成果: Article

100 引用 (Scopus)
4 引用 (Scopus)
2017
8 引用 (Scopus)
1 引用 (Scopus)
2016
13 引用 (Scopus)

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

Imamura, M., Takahashi, A., Yamauchi, T., Hara, K., Yasuda, K., Grarup, N., Zhao, W., Wang, X., Huerta-Chagoya, A., Hu, C., Moon, S., Long, J., Kwak, S. H., Rasheed, A., Saxena, R., Ma, R. C. W., Okada, Y., Iwata, M., Hosoe, J., Shojima, N. および43人, Iwasaki, M., Fujita, H., Suzuki, K., Danesh, J., Jørgensen, T., Jørgensen, M. E., Witte, D. R., Brandslund, I., Christensen, C., Hansen, T., Mercader, J. M., Flannick, J., Moreno-Macías, H., Burtt, N. P., Zhang, R., Kim, Y. J., Zheng, W., Singh, J. R., Tam, C. H. T., Hirose, H., Maegawa, H., Ito, C., Kaku, K., Watada, H., Tanaka, Y., Tobe, K., Kawamori, R., Kubo, M., Cho, Y. S., Chan, J. C. N., Sanghera, D., Frossard, P., Park, K. S., Shu, X. O., Kim, B. J., Florez, J. C., Tusié-Luna, T., Jia, W., Tai, E. S., Pedersen, O., Saleheen, D., Maeda, S. & Kadowaki, T., 2016 1 28, : : Nature communications. 7, 10531.

研究成果: Article

72 引用 (Scopus)

Replication study in a japanese population of six susceptibility loci for type 2 diabetes originally identified by a transethnic meta-analysis of genome-wide association studies

Matsuba, R., Imamura, M., Tanaka, Y., Iwata, M., Hirose, H., Kaku, K., Maegawa, H., Watada, H., Tobe, K., Kashiwagi, A., Kawamori, R. & Maeda, S., 2016 4, : : PloS one. 11, 4, e0154093.

研究成果: Article

6 引用 (Scopus)

Vitamin D deficiency with high intact PTH levels is more common in younger than in older women: A study of women aged 39–64 years

Miyamoto, T., Katsuyama, E., Kanagawa, H., Fujie, A., Miyamoto, H., Yoshida, S., Mori, T., Miyamoto, K., Sato, Y., Kobayashi, T., Nakamura, M., Matsumoto, M., Nishiwaki, Y., Hirose, H., Kanda, T., Saito, I. & Toyama, Y., 2016, : : Keio Journal of Medicine. 65, 2, p. 33-38 6 p.

研究成果: Article

5 引用 (Scopus)
2015

Palmitic acid-rich diet suppresses glucose-stimulated insulin secretion (GSIS) and induces endoplasmic reticulum (ER) stress in pancreatic islets in mice

Hirata, T., Kawai, T., Hirose, H., Tanaka, K., Kurosawa, H., Fujii, C., Fujita, H., Seto, Y., Matsumoto, H. & Itoh, H., 2015 7 10, (Accepted/In press) : : Endocrine Research.

研究成果: Article

7 引用 (Scopus)

Replication study in a Japanese population to evaluate the association between 10 SNP loci, identified in European genome-wide association studies, and type 2 diabetes

Matsuba, R., Sakai, K., Imamura, M., Tanaka, Y., Iwata, M., Hirose, H., Kaku, K., Maegawa, H., Watada, H., Tobe, K., Kashiwagi, A., Kawamori, R. & Maeda, S., 2015 5 7, : : PloS one. 10, 5, e0126363.

研究成果: Article

9 引用 (Scopus)

Replication study of the association of rs7578597 in THADA, rs10886471 in GRK5, and rs7403531 in RASGRP1 with susceptibility to type 2 diabetes among a Japanese population

Sakai, K., Imamura, M., Tanaka, Y., Iwata, M., Hirose, H., Kaku, K., Maegawa, H., Watada, H., Tobe, K., Kashiwagi, A., Kawamori, R. & Maeda, S., 2015 12 1, : : Diabetology International. 6, 4, p. 306-312 7 p.

研究成果: Article

1 引用 (Scopus)
2014

Disturbed tumor necrosis factor system is linked with lower eGFR and chronic inflammation in hypertension

Eguchi, T., Maruyama, T., Ohno, Y., Morii, T., Hirose, H., Takenaka, T., Suzuki, H., Kawabe, H., Saito, I., Hayashi, M. & Itoh, H., 2014 1 1, : : International Journal of Biological Markers. 29, 1, p. e69-e77

研究成果: Article

3 引用 (Scopus)

Genome-wide association study identifies three novel loci for type 2 diabetes

Hara, K., Fujita, H., Johnson, T. A., Yamauchi, T., Yasuda, K., Horikoshi, M., Peng, C., Hu, C., Ma, R. C. W., Imamura, M., Iwata, M., Tsunoda, T., Morizono, T., Shojima, N., So, W. Y., Leung, T. F., Kwan, P., Zhang, R., Wang, J., Yu, W. および17人, Maegawa, H., Hirose, H., Kaku, K., Ito, C., Watada, H., Tanaka, Y., Tobe, K., Kashiwagi, A., Kawamori, R., Jia, W., Chan, J. C. N., Teo, Y. Y., Shyong, T. E., Kamatani, N., Kubo, M., Maeda, S. & Kadowaki, T., 2014 1, : : Human molecular genetics. 23, 1, p. 239-246 8 p., ddt399.

研究成果: Article

100 引用 (Scopus)
2013

Assessing the clinical utility of a genetic risk score constructed using 49 susceptibility alleles for type 2 diabetes in a Japanese population

Imamura, M., Shigemizu, D., Tsunoda, T., Iwata, M., Maegawa, H., Watada, H., Hirose, H., Tanaka, Y., Tobe, K., Kaku, K., Kashiwagi, A., Kawamori, R. & Maeda, S., 2013 10, : : Journal of Clinical Endocrinology and Metabolism. 98, 10, p. E1667-E1673

研究成果: Article

22 引用 (Scopus)
12 引用 (Scopus)

Effect of telmisartan or losartan for treatment of nonalcoholic fatty liver disease: Fatty liver protection trial by telmisartan or losartan study (FANTASY)

Hirata, T., Tomita, K., Kawai, T., Yokoyama, H., Shimada, A., Kikuchi, M., Hirose, H., Ebinuma, H., Irie, J., Ojiro, K., Oikawa, Y., Saito, H., Itoh, H. & Hibi, T., 2013 9 23, : : International Journal of Endocrinology. 2013, 587140.

研究成果: Article

43 引用 (Scopus)

Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India

Saxena, R., Saleheen, D., Been, L. F., Garavito, M. L., Braun, T., Bjonnes, A., Young, R., Ho, W. K., Rasheed, A., Frossard, P., Sim, X., Hassanali, N., Radha, V., Chidambaram, M., Liju, S., Rees, S. D., Ng, D. P. K., Wong, T. Y., Yamauchi, T., Hara, K. および28人, Tanaka, Y., Hirose, H., McCarthy, M. I., Morris, A. P., Basit, A., Barnett, A. H., Katulanda, P., Matthews, D., Mohan, V., Wander, G. S., Singh, J. R., Mehra, N. K., Ralhan, S., Kamboh, M. I., Mulvihill, J. J., Maegawa, H., Tobe, K., Maeda, S., Cho, Y. S., Tai, E. S., Kelly, M. A., Chambers, J. C., Kooner, J. S., Kadowaki, T., Deloukas, P., Rader, D. J., Danesh, J. & Sanghera, D. K., 2013 5 1, : : Diabetes. 62, 5, p. 1746-1755 10 p.

研究成果: Article

102 引用 (Scopus)

Replication Study for the Association of 9 East Asian GWAS-Derived Loci with Susceptibility to Type 2 Diabetes in a Japanese Population

Sakai, K., Imamura, M., Tanaka, Y., Iwata, M., Hirose, H., Kaku, K., Maegawa, H., Watada, H., Tobe, K., Kashiwagi, A., Kawamori, R. & Maeda, S., 2013 9 25, : : PloS one. 8, 9, e76317.

研究成果: Article

29 引用 (Scopus)

Replication study for the association of a single-nucleotide polymorphism, rs3746876, within KCNJ15, with susceptibility to type 2 diabetes in a Japanese population

Fukuda, H., Imamura, M., Tanaka, Y., Iwata, M., Hirose, H., Kaku, K., Maegawa, H., Watada, H., Tobe, K., Kashiwagi, A., Kawamori, R. & Maeda, S., 2013 7 1, : : Journal of Human Genetics. 58, 7, p. 490-493 4 p.

研究成果: Article

5 引用 (Scopus)

Replication study for the association of rs391300 in SRR and rs17584499 in PTPRD with susceptibility to type 2 diabetes in a Japanese population

Imamura, M., Iwata, M., Maegawa, H., Watada, H., Hirose, H., Tanaka, Y., Tobe, K., Kaku, K., Kashiwagi, A., Kadowaki, T., Kawamori, R. & Maeda, S., 2013 3 1, : : Journal of Diabetes Investigation. 4, 2, p. 168-173 6 p.

研究成果: Article

9 引用 (Scopus)
2012

A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations

Imamura, M., Maeda, S., Yamauchi, T., Hara, K., Yasuda, K., Morizono, T., Takahashi, A., Horikoshi, M., Nakamura, M., Fujita, H., Tsunoda, T., Kubo, M., Watada, H., Maegawa, H., Okada-Iwabu, M., Iwabu, M., Shojima, N., Ohshige, T., Omori, S., Iwata, M. および11人, Hirose, H., Kaku, K., Ito, C., Tanaka, Y., Tobe, K., Kashiwagi, A., Kawamori, R., Kasuga, M., Kamatani, N., Nakamura, Y. & Kadowaki, T., 2012 7, : : Human molecular genetics. 21, 13, p. 3042-3049 8 p., dds113.

研究成果: Article

68 引用 (Scopus)

A Single Nucleotide Polymorphism within DUSP9 Is Associated with Susceptibility to Type 2 Diabetes in a Japanese Population

Fukuda, H., Imamura, M., Tanaka, Y., Iwata, M., Hirose, H., Kaku, K., Maegawa, H., Watada, H., Tobe, K., Kashiwagi, A., Kawamori, R. & Maeda, S., 2012 9 27, : : PloS one. 7, 9, e46263.

研究成果: Article

26 引用 (Scopus)
10 引用 (Scopus)
2011

A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer

Saeki, N., Saito, A., Choi, I. J., Matsuo, K., Ohnami, S., Totsuka, H., Chiku, S., Kuchiba, A., Lee, Y., Yoon, K., Kook, M., Park, S. R., Kim, Y., Tanaka, H., Tajima, K., Hirose, H., Tanioka, F., Matsuno, Y., Sugimura, H., Kato, S. および12人, Nakamura, T., Nishina, T., Yasui, W., Aoyagi, K., Sasaki, H., Yanagihara, K., Katai, H., Shimoda, T., Yoshida, T., Nakamura, Y., Hirohashi, S. & Sakamoto, H., 2011 3, : : Gastroenterology. 140, 3, p. 892-902 11 p.

研究成果: Article

84 引用 (Scopus)

Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese

Ohshige, T., Iwata, M., Omori, S., Tanaka, Y., Hirose, H., Kaku, K., Maegawa, H., Watada, H., Kashiwagi, A., Kawamori, R., Tobe, K., Kadowaki, T., Nakamura, Y. & Maeda, S., 2011 11 2, : : PloS one. 6, 10, e26911.

研究成果: Article

46 引用 (Scopus)
6 引用 (Scopus)

Genetic variants at CDC123/CAMK1D and SPRY2 are associated with susceptibility to type 2 diabetes in the Japanese population

Imamura, M., Iwata, M., Maegawa, H., Watada, H., Hirose, H., Tanaka, Y., Tobe, K., Kaku, K., Kashiwagi, A., Kawamori, R., Nakamura, Y. & Maeda, S., 2011 12 1, : : Diabetologia. 54, 12, p. 3071-3077 7 p.

研究成果: Article

25 引用 (Scopus)

Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations

Noguchi, E., Sakamoto, H., Hirota, T., Ochiai, K., Imoto, Y., Sakashita, M., Kurosaka, F., Akasawa, A., Yoshihara, S., Kanno, N., Yamada, Y., Shimojo, N., Kohno, Y., Suzuki, Y., Kang, M. J., Kwon, J. W., Hong, S. J., Inoue, K., Goto, Y. I., Yamashita, F. および14人, Asada, T., Hirose, H., Saito, I., Fujieda, S., Hizawa, N., Sakamoto, T., Masuko, H., Nakamura, Y., Nomura, I., Tamari, M., Arinami, T., Yoshida, T., Saito, H. & Matsumoto, K., 2011 7, : : PLoS Genetics. 7, 7, e1002170.

研究成果: Article

91 引用 (Scopus)
1 引用 (Scopus)
36 引用 (Scopus)
2010

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

Yamauchi, T., Hara, K., Maeda, S., Yasuda, K., Takahashi, A., Horikoshi, M., Nakamura, M., Fujita, H., Grarup, N., Cauchi, S., Ng, D. P. K., Ma, R. C. W., Tsunoda, T., Kubo, M., Watada, H., Maegawa, H., Okada-Iwabu, M., Iwabu, M., Shojima, N., Shin, H. D. および26人, Andersen, G., Witte, D. R., Jørgensen, T., Lauritzen, T., Sandbæk, A., Hansen, T., Ohshige, T., Omori, S., Saito, I., Kaku, K., Hirose, H., So, W. Y., Beury, D., Chan, J. C. N., Park, K. S., Tai, E. S., Ito, C., Tanaka, Y., Kashiwagi, A., Kawamori, R., Kasuga, M., Froguel, P., Pedersen, O., Kamatani, N., Nakamura, Y. & Kadowaki, T., 2010 10, : : Nature genetics. 42, 10, p. 864-868 5 p.

研究成果: Article

184 引用 (Scopus)

Association of increased reactive oxygen species production with abdominal obesity in type 2 diabetes

Hirao, K., Maruyama, T., Ohno, Y., Hirose, H., Shimada, A., Takei, I., Murata, M., Morii, T., Eguchi, T., Hayashi, M., Saruta, T. & Itoh, H., 2010 4 1, : : Obesity Research and Clinical Practice. 4, 2, p. e83-e90

研究成果: Article

7 引用 (Scopus)

Elevated serum adiponectin level in patients with mycobacterium avium-intracellulare complex pulmonary disease

Tasaka, S., Hasegawa, N., Nishimura, T., Yamasawa, W., Kamata, H., Shinoda, H., Kimizuka, Y., Fujiwara, H., Hirose, H. & Ishizaka, A., 2010 4 1, : : Respiration. 79, 5, p. 383-387 5 p.

研究成果: Article

23 引用 (Scopus)

Genome-wide association study of pancreatic cancer in Japanese population

Low, S. K., Kuchiba, A., Zembutsu, H., Saito, A., Takahashi, A., Kubo, M., Daigo, Y., Kamatani, N., Chiku, S., Totsuka, H., Ohnami, S., Hirose, H., Shimada, K., Okusaka, T., Yoshida, T., Nakamura, Y. & Sakamoto, H., 2010, : : PloS one. 5, 7, e11824.

研究成果: Article

93 引用 (Scopus)

Individuals susceptible to lung adenocarcinoma defined by combined HLA-DQA1 and TERT genotypes

Kohno, T., Kunitoh, H., Shimada, Y., Shiraishi, K., Ishii, Y., Goto, K., Ohe, Y., Nishiwaki, Y., Kuchiba, A., Yamamoto, S., Hirose, H., Oka, A., Yanagitani, N., Saito, R., Inoko, H. & Yokota, J., 2010 1 8, : : Carcinogenesis. 31, 5, p. 834-841 8 p.

研究成果: Article

41 引用 (Scopus)

Serum high-molecular-weight adiponectin as a marker for the evaluation and care of subjects with metabolic syndrome and related disorders

Hirose, H., Yamamoto, Y., Seino-Yoshihara, Y., Kawabe, H. & Saito, I., 2010 1 1, : : Journal of atherosclerosis and thrombosis. 17, 12, p. 1201-1211 11 p.

研究成果: Review article

公開
71 引用 (Scopus)
公開
8 引用 (Scopus)

Use of home blood pressure monitoring and exercise, diet and medication compliance in Japan

Saito, I., Nomura, M., Hirose, H. & Kawabe, H., 2010 7 1, : : Clinical and Experimental Hypertension. 32, 4, p. 210-213 4 p.

研究成果: Article

10 引用 (Scopus)
2009

CD36 single nucleotide polymorphism is associated with variation in low-density lipoprotein-cholesterol in young Japanese men

Morii, T., Ohno, Y., Kato, N., Hirose, H., Kawabe, H., Hirao, K., Eguchi, T., Maruyama, T., Hayashi, M., Saito, I., Yazaki, Y. & Saruta, T., 2009 6 1, : : Biomarkers. 14, 4, p. 207-212 6 p.

研究成果: Article

14 引用 (Scopus)
2 引用 (Scopus)

Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese

Shiraishi, K., Kohno, T., Kunitoh, H., Watanabe, S. I., Goto, K., Nishiwaki, Y., Shimada, Y., Hirose, H., Saito, I., Kuchiba, A., Yamamoto, S. & Yokota, J., 2009 2 3, : : Carcinogenesis. 30, 1, p. 65-70 6 p.

研究成果: Article

86 引用 (Scopus)
5 引用 (Scopus)
19 引用 (Scopus)

FOXP3/Scurfin gene polymorphism is associated with adult onset type 1 diabetes in Japanese, especially in women and slowly progressive-type patients

Iwase, K., Shimada, A., Kawai, T., Okubo, Y., Kanazawa, Y., Irie, J., Oikawa, Y., Hirose, H., Maruyama, T. & Itoh, H., 2009 2 3, : : Autoimmunity. 42, 2, p. 159-167 9 p.

研究成果: Article

11 引用 (Scopus)
56 引用 (Scopus)