伊藤 裕

研究成果

年別の研究成果 1985 1988 2008 2009 2010 2011 2012 2013 2014 2015 2016 2018 2019 2020 2021 2022

• 26951 被引用数
• 80 h-index
• 590 Article
• 91 Review article
• 15 Comment/debate
• 10 Letter
• 14 その他
  • 7 Editorial
  • 3 Chapter
  • 3 Short survey
  • 1 Conference contribution

年別の研究成果

年別の研究成果

検索結果

• 1986

  Bay K 8644, a voltage-sensitive calcium channel agonist, facilitates secretion of atrial natriuretic polypeptide from isolated perfused rat hearts

  Saito, Y., Nakao, K., Morri, N., Sugawara, A., Shiono, S., Yamada, T., Itoh, H., Sakamito, M., Kurahashi, K., Fujiwara, M. & Imura, H., 1986 8月 14, In: Biochemical and Biophysical Research Communications. 138, 3, p. 1170-1176 7 p.

  研究成果: Article › 査読

  • Calcium Channel Agonist 100%
  • Bay-K-8644 92%
  • Calcium Channel Agonists 85%
  • Diuretic Agent 78%
  • 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester 77%
  53 被引用数 (Scopus)

• Central action of atrial natriuretic polypeptide on blood pressure in conscious rats

  Itoh, H., Nakao, K., Morii, N., Yamada, T., Shiono, S., Sakamoto, M., Sugawara, A., Saito, Y., Katsuura, G., Shiomu, T., Eigyo, M., Matsushita, A. & Imura, H., 1986 5月, In: Brain Research Bulletin. 16, 5, p. 745-749 5 p.

  研究成果: Article › 査読

  • Peptides 100%
  • Blood Pressure 99%
  • Angiotensin II 30%
  • Central Nervous System 23%
  • Injections 18%
  65 被引用数 (Scopus)

• Central effect of atrial natriuretic polypeptide on angiotensin II-stimulated vasopressin secretion in concious rats

  Yamada, T., Nakao, K., Morii, N., Itoh, H., Shiono, S., Sakamoto, M., Sugawara, A., Saito, Y., Ohno, H., Kanai, A., Katsuura, G., Eigyo, M., Matsushita, A. & Imura, H., 1986 6月 24, In: European journal of pharmacology. 125, 3, p. 453-456 4 p.

  研究成果: Article › 査読

  • Vasopressins 100%
  • Angiotensin II 92%
  • Peptides 61%
  • Central Nervous System 23%
  • Injections 18%
  88 被引用数 (Scopus)

• Centrally administered leumorphin possesses potent depressor activity in conscious rats.

  Itoh, H., Nakao, K., Yamada, T., Morii, N., Shiono, S., Sakamoto, M., Sugawara, A., Saito, Y., Katsuura, G. & Shiomi, T., 1986, In: NIDA research monograph. 75, p. 512-515 4 p.

  研究成果: Article › 査読

  • preproenkephalin 100%
  • Angiotensin II 49%
  • Blood Pressure 43%
  • Injections 9%
  2 被引用数 (Scopus)

• Centrally infused atrial natriuretic polypeptide attenuates exaggerated salt appetite in spontaneously hypertensive rats

  Itoh, H., Nakao, K., Katsuura, G., Morii, N., Shiono, S., Sakamoto, M., Sugawara, A., Yamada, T., Saito, Y. & Matsushita, A., 1986 1月 1, In: Circulation research. 59, 3, p. 342-347 6 p.

  研究成果: Article › 査読

  Open Access

  • Inbred SHR Rats 100%
  • Appetite 96%
  • Salts 80%
  • Peptides 58%
  • Intraventricular Infusions 28%
  73 被引用数 (Scopus)

• Detection of metastatic medullary thyroid cancer with ¹³¹I-MIBG scans in Sipple's syndrome

  Itoh, H., Sugie, K., Toyooka, S., Kawase, M., Mukaino, S., Hazama, F., Endo, K., Torizuka, K., Nakao, K. & Imura, H., 1986 4月 1, In: European Journal of Nuclear Medicine. 11, 12, p. 502-504 3 p.

  研究成果: Article › 査読

  • Multiple Endocrine Neoplasia Type 2a 100%
  • Guanidine 89%
  • Medullary Thyroid cancer 87%
  • Pheochromocytoma 51%
  • Neuroblastoma 23%
  7 被引用数 (Scopus)

• Increased tissue level of atrial natriuretic polypeptide in the hypothalamus and septum of spontaneously hypertensive rats

  Morii, N., Nakao, K., Itoh, H., Sugawara, A., Sakamoto, M., Yamada, T., Shiono, S., Kihara, M., Mano, M. & Kihara, M., 1986, In: Journal of hypertension. 4, SUPPL. 3, p. S309-S312

  研究成果: Article › 査読

  • Inbred SHR Rats 100%
  • Hypothalamus 85%
  • Inbred WKY Rats 81%
  • Peptides 58%
  • Radio 46%
  11 被引用数 (Scopus)

• Inhibitory effect of centrally administered atrial natriuretic polypeptide on the brain dopaminergic system in rats

  Kazuwa, N., Goro, K., Narito, M., Hiroshi, I., Shozo, S., Akira, S., Makoto, S., Yoshihiko, S., Masami, E., Takayuki, Y., Akira, S. & Imura, H., 1986 11月 19, In: European journal of pharmacology. 131, 2-3, p. 171-177 7 p.

  研究成果: Article › 査読

  • Angiotensin II 100%
  • Peptides 65%
  • Dopamine 65%
  • Brain 50%
  • Serotonin 44%
  49 被引用数 (Scopus)

• Leumorphin is a potent inhibitor of vasopressin secretion.

  Yamada, T., Nakao, K., Itoh, H., Morii, N., Shiono, S., Sakamoto, M., Sugawara, A., Saito, Y., Katsuura, G. & Eigyo, M., 1986, In: NIDA research monograph. 75, p. 335-338 4 p.

  研究成果: Article › 査読

  • preproenkephalin 100%
  • Vasopressins 70%
  • Angiotensin II 32%
  • Injections 29%
  • Dehydration 18%
  1 被引用数 (Scopus)

• Nature of atrial natriuretic polypeptide in rat brain

  Shiono, S., Nakao, K., Morii, N., Yamada, T., Itoh, H., Sakamoto, M., Sugawara, A., Saito, Y., Katsuura, G. & Imura, H., 1986 3月 28, In: Biochemical and Biophysical Research Communications. 135, 3, p. 728-734 7 p.

  研究成果: Article › 査読

  • Diuretic Agent 100%
  • Reversed Phase HPLC 68%
  • Polypeptide 56%
  • Peptides 43%
  • Weight 36%
  96 被引用数 (Scopus)

• Possible involvement of central atrial natriuretic polypeptide in regulation of hypothalamo-pituitary-adrenal axis in conscious rats

  Itoh, H., Nakao, K., Katsuura, G., Morii, N., Yamada, T., Shiono, S., Sakamoto, M., Sugawara, A., Saito, Y., Eigyo, M., Matsushita, A. & Imura, H., 1986 9月 12, In: Neuroscience Letters. 69, 3, p. 254-258 5 p.

  研究成果: Article › 査読

  • Hypothalamo-Hypophyseal System 100%
  • Corticosterone 75%
  • Angiotensin II 45%
  • Peptides 45%
  • Injections 13%
  43 被引用数 (Scopus)

• The lung as a possible target organ for atrial natriuretic polypeptide secreted from the heart

  Sakamoto, M., Nakao, K., Morii, N., Sugawara, A., Yamada, T., Itoh, H., Shiono, S., Saito, Y. & Imura, H., 1986 3月 13, In: Biochemical and Biophysical Research Communications. 135, 2, p. 515-520 6 p.

  研究成果: Article › 査読

  • Diuretic Agent 100%
  • Polypeptide 56%
  • Heart 44%
  • Peptides 43%
  • Lung 36%
  54 被引用数 (Scopus)

• The pharmacokinetics of α-human atrial natriuretic polypeptide in healthy subjects

  Nakao, K., Sugawara, A., Morii, N., Sakamoto, M., Yamada, T., Itoh, H., Shiono, S., Saito, Y., Nishimura, K., Ban, T., Kangawa, K., Matsuo, H. & Imura, H., 1986 1月 1, In: European Journal of Clinical Pharmacology. 31, 1, p. 101-103 3 p.

  研究成果: Article › 査読

  • Pharmacokinetics 100%
  • Healthy Volunteers 88%
  • Peptides 84%
  • Intravenous Injections 63%
  87 被引用数 (Scopus)
• 1987

  Atrial natriuretic peptides. The function of the atrial natriuretic peptide as hormone and neuropeptide

  Nakao, K., Itoh, H., Saito, Y., Yamada, T., Morii, N., Sugawara, A., Shiono, S., Mukoyama, M., Arai, H. & Hosoda, K., 1987 11月, In: Nippon rinsho. Japanese journal of clinical medicine. 45, 11, p. 2581-2590 10 p.

  研究成果: Article › 査読

• Atrial natriuretic polypeptide (ANP) in human ventricle increased gene expression of ANP in dilated cardiomyopathy

  Saito, Y., Nakao, K., Arai, H., Sugawara, A., Morii, N., Yamada, T., Itoh, H., Shiono, S., Mukoyama, M., Obata, K., Yasue, H., Ohkubo, H., Nakanishi, S. & Imura, H., 1987 10月 14, In: Biochemical and Biophysical Research Communications. 148, 1, p. 211-217 7 p.

  研究成果: Article › 査読

  • Diuretic Agent 100%
  • Messenger RNA 90%
  • Dilated Cardiomyopathy 74%
  • Atrial Natriuretic Factor 63%
  • Polypeptide 56%
  55 被引用数 (Scopus)

• Atrial natriuretic polypeptide during exercise in healthy man

  Saito, Y., Nakao, K., Sugawara, A., Nishimura, K., Sakamoto, M., Morii, N., Yamada, T., Itoh, H., Shiono, S. & Kuriyama, T., 1987, In: Acta Endocrinologica. 116, 1, p. 59-65 7 p.

  研究成果: Article › 査読

  • Exercise 100%
  • Peptides 98%
  • Blood Pressure 49%
  • Exercise Test 37%
  • Norepinephrine 32%
  41 被引用数 (Scopus)

• Atrial natriuretic polypeptide in spinal cord and autonomic ganglia

  Morii, N., Nakao, K., Itoh, H., Shiono, S., Yamada, T., Sugawara, A., Saito, Y., Mukoyama, M., Arai, H., Sakamoto, M. & Imura, H., 1987 5月 29, In: Biochemical and Biophysical Research Communications. 145, 1, p. 196-203 8 p.

  研究成果: Article › 査読

  • Autonomic Ganglia 100%
  • Diuretic Agent 95%
  • Cord 80%
  • Spinal Ganglia 70%
  • Polypeptide 54%
  39 被引用数 (Scopus)

• Atrial natriuretic polypeptides: Structure-activity relationship in the central action - a comparison of their antidipsogenic actions

  Itoh, H., Nakao, K., Katsuura, G., Morii, N., Shiono, S., Yamada, T., Sugawara, A., Saito, Y., Watanabe, K., Igano, K., Inouye, K. & Imura, H., 1987 2月 10, In: Neuroscience Letters. 74, 1, p. 102-106 5 p.

  研究成果: Article › 査読

  • Structure-Activity Relationship 100%
  • Peptides 54%
  • Amides 25%
  • Drinking Water 21%
  • Angiotensin II 20%
  22 被引用数 (Scopus)

• Central Actions of Atrial Netriuretic Polypeptides in Spontaneously Hypertensive and Normotensive rats

  Itoh, H., Morii, N., Sugawara, A., Yamada, T., Shiono, S., Saito, Y., Mukoyama, M., Arai, H., Sakamoto, M., Imura, H. & Nakao, K., 1987, In: JAPANESE CIRCULATION JOURNAL. 51, 10, p. 1208-1215 8 p.

  研究成果: Article › 査読

  Open Access

  • Inbred SHR Rats 100%
  • Atrial Natriuretic Factor 81%
  • Peptides 58%
  • Drinking 50%
  • atrial natriuretic factor (4-28) 39%
  6 被引用数 (Scopus)

• Conversion of β-human atrial natriuretic polypeptide into α-human atrial natriuretic polypeptide in human plasma in vitro

  Itoh, H., Nakao, K., Shiono, S., Mukoyama, M., Morii, N., Sugawara, A., Yamada, T., Saito, Y., Arai, H., Kambayashi, Y., Inouye, K. & Imura, H., 1987 3月 13, In: Biochemical and Biophysical Research Communications. 143, 2, p. 560-569 10 p.

  研究成果: Article › 査読

  • Diuretic Agent 100%
  • Polypeptide 56%
  • Atrial Natriuretic Factor 45%
  • Peptides 43%
  • Plasma 42%
  21 被引用数 (Scopus)

• Modulatory role of vasopressin in secretion of atrial natriuretic polypeptide in conscious rats

  Itoh, H., Nakao, K., Yamada, T., Morii, N., Shiono, S., Sugawara, A., Saito, Y., Mukoyama, M., Arai, H., Katsuura, G., Eigyo, N., Matsushita, A. & Imura, H., 1987 5月, In: Endocrinology. 120, 5, p. 2186-2188 3 p.

  研究成果: Article › 査読

  • Arginine Vasopressin 100%
  • Vasopressins 87%
  • Peptides 53%
  • Natriuretic Agents 19%
  • Vasopressin Receptors 18%
  36 被引用数 (Scopus)

• Secretory form of atrial natriuretic polypeptide as cardiac hormone in humans and rats

  Nakao, K., Sugawara, A., Shiono, S., Saito, Y., Morii, N., Yamada, T., Itoh, H., Mukoyama, M., Arai, H., Sakamoto, M. & Imura, H., 1987 1月 1, In: Canadian Journal of Physiology and Pharmacology. 65, 8, p. 1756-1761 6 p.

  研究成果: Article › 査読

  • Hormones 100%
  • Peptides 90%
  • Coronary Sinus 33%
  • Molecular Weight 31%
  • Reverse-Phase Chromatography 23%
  23 被引用数 (Scopus)

• Simultaneous measurement of atrial natriuretic polypeptide (ANP) messenger RNA and ANP in rat heart - Evidence for a preferentially increased synthesis and secretion of ANP in left atrium of spontaneously hypertensive rats (SHR) -

  Arai, H., Nakao, K., Saito, Y., Morii, N., Sugawara, A., Yamada, T., Itoh, H., Shiono, S., Mukoyama, M., Ohkubo, H., Nakanishi, S. & Imura, H., 1987 10月 14, In: Biochemical and Biophysical Research Communications. 148, 1, p. 239-245 7 p.

  研究成果: Article › 査読

  • Diuretic Agent 100%
  • Hypertensive 94%
  • Messenger RNA 90%
  • Inbred SHR Rats 74%
  • Heart Atria 68%
  24 被引用数 (Scopus)
• 1988

  A monoclonal antibody against N-terminus of α-atrial natriuretic polypeptide (α-ANP): A useful tool for preferential detection of naturally circulating ANP

  Mukoyama, M., Nakao, K., Yamada, T., Itoh, H., Sugawara, A., Saito, Y., Arai, H., Hosoda, K., Shirakami, G., Morii, N., Shiono, S. & Imura, H., 1988 1月 1, In: Biochemical and Biophysical Research Communications. 151, 3, p. 1277-1284 8 p.

  研究成果: Article › 査読

  • Diuretic Agent 100%
  • Atrial Natriuretic Factor 76%
  • Polypeptide 56%
  • Monoclonal Antibodies 50%
  • Peptides 43%
  22 被引用数 (Scopus)

• A monoclonal antibody to α-human atrial natriuretic polypeptide

  Mukoyama, M., Nakao, K., Sugawa, H., Morii, N., Sugawara, A., Yamada, T., Itoh, H., Shiono, S., Saito, Y., Arai, H., Mori, T., Yamada, H., Sano, Y. & Imura, H., 1988, In: Hypertension. 12, 2, p. 117-121 5 p.

  研究成果: Article › 査読

  Open Access

  • Atrial Natriuretic Factor 100%
  • Radioimmunoassay 72%
  • Monoclonal Antibodies 65%
  • Peptides 57%
  • Carbodiimides 19%
  20 被引用数 (Scopus)

• Antidipsogenic action of a novel peptide, 'brain natriuretic peptide', in rats

  Itoh, H., Nakao, K., Yamada, T., Shirakami, G., Kangawa, K., Minamimo, N., Matsuo, H. & Imura, H., 1988 5月 20, In: European journal of pharmacology. 150, 1-2, p. 193-196 4 p.

  研究成果: Article › 査読

  • rat natriuretic peptide precursor type B 100%
  • Brain Natriuretic Peptide 57%
  • Drinking 35%
  • Peptides 32%
  • Drinking Water 12%
  75 被引用数 (Scopus)

• Atrial natriuretic factor in essential hypertension and adrenal disorders

  Sugawara, A., Nakao, K., Kono, T., Morii, N., Yamada, T., Itoh, H., Shiono, S., Saito, Y., Mukoyama, M., Arai, H. & Imura, H., 1988 2月, In: Hypertension. 11, 2, p. I-212-I-216

  研究成果: Article › 査読

  Open Access

  • Atrial Natriuretic Factor 100%
  • Essential Hypertension 94%
  • Hyperaldosteronism 34%
  • Glandular and Epithelial Neoplasms 10%
  • Renin 9%
  29 被引用数 (Scopus)

• Atrial natriuretic polypeptide as a neuropeptide

  Nakao, K., Morii, N., Itoh, H., Yamada, T., Shiono, S., Sugawara, A., Saito, Y., Mukoyama, M., Arai, H., Sakamoto, M., Katsuura, G., Matsushita, A., Kawata, M., Sano, Y. & Imura, H., 1988, In: Therapeutic Research. 8, 6, p. 37-41 5 p.

  研究成果: Article › 査読

• Atrial natriuretic polypeptide in bovine adrenal medulla

  Mukoyama, M., Nakao, K., Morii, N., Shiono, S., Itoh, H., Sugawara, A., Yamada, T., Saito, Y., Arai, H. & Mura, H., 1988 6月, In: Hypertension. 11, 6, p. 692-696 5 p.

  研究成果: Article › 査読

  Open Access

  • Adrenal Medulla 100%
  • Atrial Natriuretic Factor 87%
  • Cattle 63%
  • Chromaffin Cells 50%
  • Peptides 50%
  19 被引用数 (Scopus)

• Augmented expression of atrial natriuretic polypeptide gene in ventricles of spontaneously hypertensive rats (SHR) and SHR-stroke prone

  Arai, H., Nakao, K., Saito, Y., Morii, N., Sugawara, A., Yamada, T., Itoh, H., Shiono, S., Mukoyama, M., Ohkubo, H., Nakanishi, S. & Imura, H., 1988, In: Circulation research. 62, 5, p. 926-930 5 p.

  研究成果: Article › 査読

  Open Access

  • Inbred SHR Rats 100%
  • Stroke 62%
  • Peptides 58%
  • Inbred WKY Rats 40%
  • Genes 37%
  110 被引用数 (Scopus)

• Augmented synthesis of β-human atrial natriuretic polypeptide in human failing hearts

  Sugawara, A., Nakao, K., Morii, N., Yamada, T., Itoh, H., Shiono, S., Saito, Y., Mukoyama, M., Arai, H., Nishimura, K., Obata, K., Yasue, H., Ban, T. & Imura, H., 1988 1月 15, In: Biochemical and Biophysical Research Communications. 150, 1, p. 60-67 8 p.

  研究成果: Article › 査読

  • Diuretic Agent 100%
  • Polypeptide 56%
  • Heart 44%
  • Peptides 43%
  • Heart Failure 33%
  9 被引用数 (Scopus)

• Brain renin-angiotensin: Central control of secretion of atrial natriuretic factor from the heart

  Itoh, H., Nakao, K., Yamada, T., Morii, N., Shiono, S., Sugawara, A., Saito, Y., Mukoyama, M., Arai, H. & Imura, H., 1988 2月, In: Hypertension. 11, 2, p. I-57-I-61

  研究成果: Article › 査読

  Open Access

  • Angiotensins 100%
  • Atrial Natriuretic Factor 96%
  • Renin 87%
  • Angiotensin II 60%
  • Heart 56%
  18 被引用数 (Scopus)

• Central interaction of the brain atrial natriuretic polypeptide (ANP) system and the brain renin-angiotensin system in ANP secretion from heart - evidence for possible brain-heart axis

  Itoh, H., Nakao, K., Yamada, T., Morii, N., Shiono, S., Sugawara, A., Saito, Y., Mukoyama, M., Arai, H. & Imura, H., 1988, In: Canadian Journal of Physiology and Pharmacology. 66, 3, p. 255-269 15 p.

  研究成果: Article › 査読

  • Renin-Angiotensin System 100%
  • Heart 62%
  • Peptides 61%
  • Angiotensin II 50%
  • Brain 47%
  6 被引用数 (Scopus)

• Cosecretion of peptides derived from gamma-human atrial natriuretic polypeptide in normal volunteers and patients with essential hypertension and adrenal disorders

  Sugawara, A., Nakao, K., Itoh, H., Yamada, T., Saito, Y., Mukoyama, M., Arai, H., Hosoda, K., Shirakami, G., Morii, N., Shiono, S. & Imura, H., 1988 12月, In: Journal of Hypertension, Supplement. 6, 4, p. S327-S329

  研究成果: Article › 査読

  • Essential Hypertension 100%
  • Healthy Volunteers 63%
  • Peptides 60%
  • Atrial Natriuretic Factor 35%
  • anaritide 31%
  7 被引用数 (Scopus)

• Effects of intravenously administered β-human atrial natriuretic polypeptide in humans

  Itoh, H., Nakao, K., Mukoyama, M., Shiono, S., Morii, N., Sugawara, A., Yamada, T., Saito, Y., Arai, H., Hosoda, K., Kambayashi, Y., Inouye, K. & Imura, H., 1988 6月, In: Hypertension. 11, 6, p. 697-702 6 p.

  研究成果: Article › 査読

  Open Access

  • Peptides 100%
  • Atrial Natriuretic Factor 49%
  • Radioimmunoassay 42%
  • Blood Pressure 28%
  • Gel Chromatography 22%
  13 被引用数 (Scopus)

• Exaggerated secretion of atrial natriuretic polypeptide during dynamic exercise in patients with essential hypertension

  Saito, Y., Nakao, K., Sugawara, A., Nishimura, K., Morii, N., Yamada, T., Itoh, H., Shiono, S., Mukoyama, M., Arai, H., Sakamoto, M., Ban, T. & Imura, H., 1988 10月, In: American heart journal. 116, 4, p. 1052-1057 6 p.

  研究成果: Article › 査読

  • Essential Hypertension 100%
  • Exercise 61%
  • Peptides 60%
  • Blood Pressure 60%
  • Heart Rate 23%
  20 被引用数 (Scopus)

• Expression of atrial natriuretic factor gene in hearts from neonates of spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats

  Arai, H., Nakao, K., Saito, Y., Sugawara, A., Yamada, T., Itoh, H., Mukoyama, M., Hosoda, K., Shirakami, G., Morii, N., Shiono, S., Ohkubo, H., Nakanishi, S. & Imura, H., 1988 12月, In: Journal of Hypertension, Supplement. 6, 4, p. S276-S278

  研究成果: Article › 査読

  • Atrial Natriuretic Factor 100%
  • Inbred SHR Rats 97%
  • Stroke 61%
  • Heart 58%
  • Inbred WKY Rats 53%
  2 被引用数 (Scopus)

• Implication of leumorphin in inhibitory control of vasopressin secretion in conscious rats

  Yamada, T., Nakao, K., Itoh, H., Morii, N., Shiono, S., Sakamoto, M., Sugawara, A., Saito, Y., Mukoyama, M., Arai, H. & Imura, H., 1988 2月, In: Hypertension. 11, 2, p. I-80-I-83

  研究成果: Article › 査読

  Open Access

  • preproenkephalin 100%
  • Vasopressins 70%
  • Injections 22%
  • Naloxone 20%
  • Angiotensin II 18%
  5 被引用数 (Scopus)

• Inhibitory action of leumorphin on vasopressin secretion in conscious rats

  Yamada, T., Nakao, K., Itoh, H., Morii, N., Shiono, S., Sakamoto, M., Sugawara, A., Saito, Y., Mukoyama, M., Arai, H., Eigyo, M., Matsushita, A. & Imura, H., 1988 3月 1, In: Endocrinology. 122, 3, p. 985-990 6 p.

  研究成果: Article › 査読

  • preproenkephalin 100%
  • Arginine Vasopressin 80%
  • Vasopressins 70%
  • Injections 23%
  • proenkephalin 10%
  17 被引用数 (Scopus)

• Inhibitory effect of brain natriuretic peptide on central angiotensin II-stimulated pressor response in conscious rats

  Shirakami, G., Nakao, K., Yamada, T., Itoh, H., Mori, K., Kangawa, K., Minamino, N., Matsuo, H. & Imura, H., 1988 8月 15, In: Neuroscience Letters. 91, 1, p. 77-83 7 p.

  研究成果: Article › 査読

  • Brain Natriuretic Peptide 100%
  • Angiotensin II 87%
  • Blood Pressure 57%
  • Heart Rate 44%
  • Injections 34%
  61 被引用数 (Scopus)

• Intracerebroventricular injection of brain natriuretic peptide inhibits vasopressin secretion in conscious rats

  Yamada, T., Nakao, K., Itoh, H., Shirakami, G., Kangawa, K., Minamino, N., Matsuo, H. & Imura, H., 1988 12月 19, In: Neuroscience Letters. 95, 1-3, p. 223-228 6 p.

  研究成果: Article › 査読

  • Brain Natriuretic Peptide 100%
  • Vasopressins 94%
  • Arginine Vasopressin 86%
  • Injections 52%
  • Peptides 46%
  54 被引用数 (Scopus)

• Involvement of leumorphin in central control of body fluid and blood pressure

  Nakao, K., Yamada, T., Itoh, H. & Imura, H., 1988, In: Therapeutic Research. 9, 2, p. 119-124 6 p.

  研究成果: Article › 査読

• Opioid modulation of vasopressin secretion in conscious rats

  Yamada, T., Nakao, K., Itoh, H., Shirakami, G., Sugawara, A., Saito, Y., Mukoyama, M., Arai, H., Hosoda, K., Morii, N., Shiono, S. & Imura, H., 1988, In: Clinical and Experimental Hypertension. A10, S1, p. 361-367 7 p.

  研究成果: Article › 査読

  • Vasopressins 100%
  • preproenkephalin 94%
  • Opioid Analgesics 84%
  • Opioid Peptides 78%
  • Naloxone 67%
  5 被引用数 (Scopus)

• Peptides derived from atrial natriuretic polypeptide precursor in human and monkey brains

  Itoh, H., Nakao, K., Mukoyama, M., Hosada, K., Shiono, S., Morii, N., Yamada, T., Sugawara, A., Saito, Y., Arai, H., Shirakami, G. & Imura, H., 1988 12月, In: Journal of Hypertension, Supplement. 6, 4, p. S309-S313

  研究成果: Article › 査読

  • Atrial Natriuretic Factor 100%
  • Haplorhini 83%
  • Peptides 57%
  • Brain 44%
  • Radio 27%
  5 被引用数 (Scopus)

• Possible antagonistic relationship between atrial natriuretic peptide (ANP)-brain natriuretic peptide (BNP) system and brain renin-angiotensin system in central control of body fluid and cardiovascular function

  Nakao, K., Yamada, T., Itoh, H., Shirakami, G., Saito, Y., Sugawara, A., Mukoyama, M., Arai, H., Hosoda, K., Morii, N., Shiono, S., Minamino, N., Kangawa, K., Matsuo, H. & Imura, H., 1988, In: Clinical and Experimental Hypertension - Part A Theory and Practice. 10, 6, p. 1289-1291 3 p.

  研究成果: Article › 査読
  1 被引用数 (Scopus)

• Potent depressor action of leumorphin, a κ-opioia agonist, in conscious rats

  Itoh, H., Nakao, K., Yamada, T., Morii, N., Shiono, S., Sakamoto, M., Sugawara, A., Saito, Y., Mukoyama, M., Arai, H. & Imura, H., 1988 7月, In: American journal of hypertension. 1, 3, p. 256-261 6 p.

  研究成果: Article › 査読

  • preproenkephalin 100%
  • Blood Pressure 24%
  • Arterial Pressure 15%
  • proenkephalin 14%
  • Dynorphins 13%
  3 被引用数 (Scopus)

• Preparation of monoclonal antibodies against atrial natriuretic polypeptide precursor and application to highly sensitive sandwich enzyme immunoassay

  Mukoyama, M., Nakao, K., Yamada, T., Itoh, H., Hosoda, K., Saito, Y., Sugawara, A., Arai, H., Shirakami, G., Morii, N., Shiono, S., Hashida, S., Ishikawa, E. & Imura, H., 1988 12月, In: Journal of Hypertension, Supplement. 6, 4, p. S320-S322

  研究成果: Article › 査読

  • Immunoenzyme Techniques 100%
  • Monoclonal Antibodies 71%
  • Peptides 62%
  • Atrial Natriuretic Factor 19%
  • anaritide 17%
  3 被引用数 (Scopus)

• Secretion of N-terminal fragment of γ-human atrial natriuretic polypeptide

  Itoh, H., Nakao, K., Mukoyama, M., Sugawara, A., Saito, Y., Morii, N., Yamada, T., Shiono, S., Arai, H. & Imura, H., 1988 2月, In: Hypertension. 11, 2, p. I-52-I-56

  研究成果: Article › 査読

  • Peptides 100%
  • Radioimmunoassay 21%
  • Atrial Natriuretic Factor 16%
  • Molecular Weight 12%
  • Atrial Pressure 9%
  48 被引用数 (Scopus)

• Synthesis of atrial natriuretic polypeptide in human failing hearts. Evidence for altered processing of atrial natriuretic polypeptide precursor and augmented synthesis of β-human ANP

  Sugawara, A., Nakao, K., Morii, N., Yamada, T., Itoh, H., Shiono, S., Saito, Y., Mukoyama, M., Arai, H., Nishimura, K., Obata, K., Yasue, H., Ban, T. & Imura, H., 1988, In: Journal of Clinical Investigation. 81, 6, p. 1962-1970 9 p.

  研究成果: Article › 査読

  Open Access

  • Heart 100%
  • Peptides 98%
  • Heart Failure 65%
  • Human Rights 33%
  • Reverse-Phase Chromatography 16%
  86 被引用数 (Scopus)

• Treatment of congestive heart failure with atrial natriuretic polypeptide

  Saito, Y., Nakao, K., Sugawara, A., Morii, N., Yamada, T., Itoh, H., Mukoyama, M., Arai, H., Hosoda, K., Shirakami, G., Nishimura, K., Okumura, K., Obata, K., Ban, T., Yasue, H. & Imura, H., 1988 1月 1, In: Saishin-Igaku. 43, 1, p. 118-127 10 p.

  研究成果: Article › 査読