Hiroshi Itoh

1997

Altered expression of atrial natriuretic peptide and contractile protein genes in hypertrophied ventricle of JVS mice with systemic carnitine deficiency

Yoshimine, K., Horiuchi, M., Suzuki, S., Kobayashi, K., Abdul, J. M., Masuda, M., Tomomura, M., Ogawa, Y., Itoh, H., Nakao, K., Osame, M. & Saheki, T., 1997 2月, In: Journal of Molecular and Cellular Cardiology. 29, 2, p. 571-578 8 p.

研究成果: Article › 査読

21 被引用数 (Scopus)

Cloning of rat uncoupling protein-3 and uncoupling protein-2 cDNAs: Their gene expression in rats fed high-fat diet

Matsuda, J., Hosoda, K., Itoh, H., Son, C., Doi, K., Tanaka, T., Fukunaga, Y., Inoue, G., Nishimura, H., Yoshimasa, Y., Yamori, Y. & Nakao, K., 1997 11月 24, In: FEBS Letters. 418, 1-2, p. 200-204 5 p.

研究成果: Article › 査読

181 被引用数 (Scopus)

Expression of natriuretic peptide system during embryonic stem cell vasculogenesis

Doi, K., Itoh, H., Nakagawa, O., Igaki, T., Yamashita, J., Chun, T. H., Inoue, M., Masatsugu, K. & Nakao, K., 1997 12月 1, In: Heart and vessels. 12, SUPPL. 12, p. 18-22 5 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Impaired guanosine 3',5'-cyclic phosphate production in severe pregnancy-induced hypertension with high plasma levels of atrial and brain natriuretic peptides

Itoh, H., Sagawa, N., Nanno, H., Mori, T., Mukoyama, M., Itoh, H. & Nakao, K., 1997 6月, In: Endocrine journal. 44, 3, p. 389-393 5 p.

研究成果: Article › 査読

Open Access

23 被引用数 (Scopus)

Opposite regulation of Gax homeobox expression by angiotensin II and C- type natriuretic peptide

Yamashita, J., Itoh, H., Ogawa, Y., Tamura, N., Takaya, K., Igaki, T., Doi, K., Chun, T. H., Inoue, M., Masatsugu, K. & Nakao, K., 1997 1月, In: Hypertension. 29, 1 II, p. 381-387 7 p.

研究成果: Article › 査読

Open Access

34 被引用数 (Scopus)

Plasma levels of brain and atrial natriuretic peptides elevate in proportion to left ventricular end-systolic wall stress in patients with aortic stenosis.

Ikeda, T., Matsuda, K., Itoh, H., Shirakami, G., Miyamoto, Y., Yoshimasa, T., Nakao, K. & Ban, T., 1997 3月, In: American heart journal. 133, 3, p. 307-314 8 p.

研究成果: Article › 査読

113 被引用数 (Scopus)

Role of cardiac nonmyocytes in cyclic mechanical stretch-induced myocyte hypertrophy

Harada, M., Saito, Y., Nakagawa, O., Miyamoto, Y., Ishikawa, M., Kuwahara, K., Ogawa, E., Nakayama, M., Kamitani, S., Hamanaka, I., Kajiyama, N., Masuda, I., Itoh, H., Tanaka, I. & Nakao, K., 1997 12月 1, In: Heart and vessels. 12, SUPPL. 12, p. 198-200 3 p.

研究成果: Article › 査読

20 被引用数 (Scopus)

Shear stress augments expression of C-type natriuretic peptide and adrenomedullin

Chun, T. H., Itoh, H., Ogawa, Y., Tamura, N., Takaya, K., Igaki, T., Yamashita, J., Doi, K., Inoue, M., Masatsugu, K., Korenaga, R., Ando, J. & Nakao, K., 1997 6月, In: Hypertension. 29, 6, p. 1296-1302 7 p.

研究成果: Article › 査読

177 被引用数 (Scopus)

Significance of vascular natriuretic peptide system in vascular remodeling in humans and its application to gene therapy

Itoh, H., Suga, S. I., Ogawa, Y., Komatsu, Y., Tamura, N., Igaki, T., Yamashita, J., Ikeda, T., Doi, K., Chun, T. H., Inoue, M., Matsuda, K., Yoshimasa, T., Ueda, M., Ban, T. & Nakao, K., 1997, In: Annals of the New York Academy of Sciences. 811, p. 533-541 9 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Significance of ventricular myocytes and nonmyocytes interaction during cardiocyte hypertrophy: Evidence for endothelin-1 as a paracrine hypertrophic factor from cardiac nonmyocytes

Harada, M., Itoh, H., Nakagawa, O., Ogawa, Y., Miyamoto, Y., Kuwahara, K., Ogawa, E., Igaki, T., Yamashita, J., Masuda, I., Yoshimasa, T., Tanaka, I., Saito, Y. & Nakao, K., 1997 11月 18, In: Circulation. 96, 10, p. 3737-3744 8 p.

研究成果: Article › 査読

211 被引用数 (Scopus)

1996

Alternative RNA splicing of the human endothelin-A receptor generates multiple transcripts

Miyamoto, Y., Yoshimasa, T., Arai, H., Takaya, K., Ogawa, Y., Itoh, H. & Nakao, K., 1996 2月 1, In: Biochemical Journal. 313, 3, p. 795-801 7 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

cDNA cloning and gene expression of human type Iα cGMP-dependent protein kinase

Tamura, N., Itoh, H., Ogawa, Y., Nakagawa, O., Harada, M., Chun, T. H., Suga, S. I., Yoshimasa, T. & Nakao, K., 1996 3月, In: Hypertension. 27, 3 II, p. 552-557 6 p.

研究成果: Article › 査読

67 被引用数 (Scopus)

C-type natriuretic peptide as an autocrine/paracrine regulator of osteoblast: Evidence for possible presence of bone natriuretic peptide system

Suda, M., Tanaka, K., Fukushima, M., Natsui, K., Yasoda, A., Komatsu, Y., Ogawa, Y., Itoh, H. & Nakao, K., 1996 6月 5, In: Biochemical and Biophysical Research Communications. 223, 1, p. 1-6 6 p.

研究成果: Article › 査読

60 被引用数 (Scopus)

C-type natriuretic peptide in chronic renal failure and its action in humans

Igaki, T., Itoh, H., Suga, S., Hama, N., Ogawa, Y., Komatsu, Y., Mukoyama, M., Sugawara, A., Yoshimasa, T., Tanaka, I. & Nakao, K., 1996 1月 1, In: Kidney International, Supplement. 55, p. S-144-S-147

研究成果: Article › 査読

57 被引用数 (Scopus)

C-type natriuretic peptide in human coronary atherosclerotic lesions

Naruko, T., Ueda, M., Van der Wal, A. C., Van der Loos, C. M., Itoh, H., Nakao, K. & Becker, A. E., 1996, In: Circulation. 94, 12, p. 3103-3108 6 p.

研究成果: Article › 査読

58 被引用数 (Scopus)

Expression of the RET proto-oncogene in normal human tissues, pheochromocytomas, and other tumors of neural crest origin

Takaya, K., Yoshimasa, T., Arai, H., Tamura, N., Miyamoto, Y., Itoh, H. & Nakao, K., 1996 10月 25, In: Journal of Molecular Medicine. 74, 10, p. 617-621 5 p.

研究成果: Article › 査読

41 被引用数 (Scopus)

Insulin suppresses endothelial secretion of C-type natriuretic peptide, a novel endothelium-derived relaxing peptide

Igaki, T., Itoh, H., Suga, S. I., Komatsu, Y., Ogawa, Y., Doi, K., Yoshimasa, T. & Nakao, K., 1996, In: Diabetes. 45, 3 SUPPL., p. S62-S64

研究成果: Article › 査読

30 被引用数 (Scopus)

Natriuretic peptide receptors in human artery and vein and rabbit vein graft

Ikeda, T., Itoh, H., Komatsu, Y., Hanyu, M., Yoshimasa, T., Matsuda, K., Nakao, K. & Ban, T., 1996 3月, In: Hypertension. 27, 3 II, p. 833-837 5 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Regulation of endothelial production of C-type natriuretic peptide in coculture with vascular smooth muscle cells: Role of the vascular natriuretic peptide system in vascular growth inhibition

Komatsu, Y., Itoh, H., Suga, S. I., Ogawa, Y., Hama, N., Kishimoto, I., Nakagawa, O., Igaki, T., Doi, K., Yoshimasa, T. & Nakao, K., 1996 4月, In: Circulation research. 78, 4, p. 606-614 9 p.

研究成果: Article › 査読

83 被引用数 (Scopus)

Regulation of secretion and clearance of C-type natriuretic peptide in the interaction of vascular endothelial cells and smooth muscle cells

Komatsu, Y., Itoh, H., Suga, S. I., Igaki, T., Ogawa, Y., Kishimoto, I., Nakagawa, O., Yoshimasa, T. & Nakao, K., 1996 6月 7, In: Journal of hypertension. 14, 5, p. 585-592 8 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Roles of natriuretic peptides in heart failure

Nakao, K., Saito, Y., Itoh, H., Ogawa, Y., Nakagawa, O., Harada, M., Masuda, I. & Yoshimasa, T., 1996, In: Journal of Cardiac Failure. 2, SUPPL. 1, p. S129-S133

研究成果: Article › 査読

3 被引用数 (Scopus)

The RET proto-oncogene in sporadic pheochromocytomas

Takaya, K., Yoshimasa, T., Arai, H., Tamura, N., Miyamoto, Y., Itoh, H. & Nakao, K., 1996 6月, In: Internal Medicine. 35, 6, p. 449-452 4 p.

研究成果: Article › 査読

Open Access

10 被引用数 (Scopus)

Two cardiac natriuretic peptide genes (Atrial natriuretic peptide and brain natriuretic peptide) are organized in tandem in the mouse and human genomes

Tamura, N., Ogawa, Y., Yasoda, A., Itoh, H., Saito, Y. & Nakao, K., 1996 8月, In: Journal of Molecular and Cellular Cardiology. 28, 8, p. 1811-1815 5 p.

研究成果: Article › 査読

77 被引用数 (Scopus)

Type 2 angiotensin II receptor is expressed in human myometrium and uterine leiomyoma and is down-regulated during pregnancy

Matsumoto, T., Sagawa, N., Mukoyama, M., Tanaka, I., Itoh, H., Goto, M., Itoh, H., Horiuchi, M., Dzau, V. J., Mori, T. & Nakao, K., 1996 12月 19, In: Journal of Clinical Endocrinology and Metabolism. 81, 12, p. 4366-4372 7 p.

研究成果: Article › 査読

32 被引用数 (Scopus)

Vascular endothelial growth factor suppresses C-type natriuretic peptide secretion

Doi, K., Itoh, H., Komatsu, Y., Igaki, T., Chun, T. H., Takaya, K., Yamashita, J., Inoue, M., Yoshimasa, T. & Nakao, K., 1996 3月, In: Hypertension. 27, 3 II, p. 811-815 5 p.

研究成果: Article › 査読

44 被引用数 (Scopus)

1995

ALTERED GENE EXPRESSION OF NATRIURETIC PEPTIDE RECEPTOR SUBTYPES IN THE KIDNEY OF STROKE‐PRONE SPONTANEOUSLY HYPERTENSIVE RATS

Goto, M., Itoh, H., Tanaka, I., Suga, S. ., Ogawa, Y., Kishimoto, I., Nakagawa, M., Sugawara, A., Yoshimasa, T., Mukoyama, M. & Nakao, K., 1995 11月, In: Clinical and Experimental Pharmacology and Physiology. 22, p. S177-S179

研究成果: Article › 査読

6 被引用数 (Scopus)

AUGMENTED EXPRESSION OF THE ENDOTHELIN‐A RECEPTOR GENE IN CULTURED MESANGIAL CELLS FROM STROKE‐PRONE SPONTANEOUSLY HYPERTENSIVE RATS

Hiraoka, J., Arai, H., Yoshimasa, T., Takaya, K., Miyamoto, Y., Yamashita, J., Suga, S. ., Ogawa, Y., Shirakami, G., Itoh, H., Yamori, Y. & Nakao, K., 1995 11月, In: Clinical and Experimental Pharmacology and Physiology. 22, p. S191-S192

研究成果: Article › 査読

2 被引用数 (Scopus)

Characterization of the 5′-flanking region and chromosomal assignment of the human brain natriuretic peptide gene

Ogawa, Y., Itoh, H., Nakagawa, O., Shirakami, G., Tamura, N., Yoshimasa, T., Nagata, K., Yoshida, N. & Nakao, K., 1995 9月 1, In: Journal of Molecular Medicine. 73, 9, p. 457-463 7 p.

研究成果: Article › 査読

21 被引用数 (Scopus)

Cis elements for transcriptional regulation of the human endothelin-A receptor gene

Yamashita, J., Yoshimasa, T., Arai, H., Hiraoka, J., Takaya, K., Miyamoto, Y., Ogawa, Y., Itoh, H. & Nakao, K., 1995, In: Journal of Cardiovascular Pharmacology. 26, p. S26-S28

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

ENDOTHELIN‐INDUCED ACTIVATION OF MITOGEN‐ACTIVATED PROTEIN KINASES IN GLOMERULAR MESANGIAL CELLS FROM NORMOTENSIVE AND STROKE‐PRONE SPONTANEOUSLY HYPERTENSIVE RATS

Kishimoto, I., Yoshimasa, T., Arai, H., Takaya, K., Miyamoto, Y., Yamashita, J., Suga, S., Komatsu, Y., Nakagawa, O., Tanaka, I., Itoh, H. & Nakao, K., 1995 11月, In: Clinical and Experimental Pharmacology and Physiology. 22, p. S207-S208

研究成果: Article › 査読

4 被引用数 (Scopus)

Gene expression of natriuretic peptide receptor subtypes in the kidney of SHR-stroke prone

Goto, M., Itoh, H., Suga, S. I., Ogawa, Y., Kishimoto, I., Nakagawa, M., Mukoyama, M., Sugawara, A., Yoshimasa, T., Tanaka, I. & Nakao, K., 1995, In: japanese heart journal. 36, 4, p. 532 1 p.

研究成果: Article › 査読

Open Access

GENE EXPRESSION OF PROSTACYCLIN RECEPTOR IN THE HYPERTROPHIED HEART OF SPONTANEOUSLY HYPERTENSIVE RATS

Nakagawa, O., Sasaki, Y., Tanaka, I., Usui, T., Sando, T., Muro, S., Mori, K., Itoh, H., Yoshimasa, T., Narumiya, S. & Nakao, K., 1995 11月, In: Clinical and Experimental Pharmacology and Physiology. 22, p. S270-S272

研究成果: Article › 査読

4 被引用数 (Scopus)

GENE REGULATION OF BRAIN NATRIURETIC PEPTIDE IN CARDIOCYTE HYPERTROPHY BY α₁‐ADRENERGIC STIMULATION

Nakagawa, O., Itoh, H., Harada, M., Komatsu, Y., Yoshimasa, T. & Nakao, K., 1995 11月, In: Clinical and Experimental Pharmacology and Physiology. 22, p. S183-S185

研究成果: Article › 査読

8 被引用数 (Scopus)

Lipoproteins regulate C-type natriuretic peptide secretion from cultured vascular endothelial cells

Sugiyama, S., Kugiyama, K., Matsumura, T., Suga, S. I., Itoh, H., Nakao, K. & Yasue, H., 1995 11月, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 15, 11, p. 1968-1974 7 p.

研究成果: Article › 査読

40 被引用数 (Scopus)

MOLECULAR BIOLOGY AND BIOCHEMISTRY OF NATRIURETIC PEPTIDE FAMILY

Ogawa, Y., Itoh, H. & Nakao, K., 1995 1月, In: Clinical and Experimental Pharmacology and Physiology. 22, 1, p. 49-54 6 p.

研究成果: Article › 査読

76 被引用数 (Scopus)

Multiple transcripts of human endothelin-A receptor gene detected by reverse transcription and the polymerase chain reaction

Miyamoto, Y., Yoshimasa, T., Arai, H., Takaya, K., Ogawa, Y., Itoh, H. & Nakao, K., 1995, In: Journal of Cardiovascular Pharmacology. 26, p. S29-S31

研究成果: Article › 査読

Open Access

5 被引用数 (Scopus)

PREPARATION OF A MONOCLONAL ANTIBODY AGAINST MOUSE BRAIN NATRIURETIC PEPTIDE (BNP) AND TISSUE DISTRIBUTION OF BNP IN MICE

Nakagawa, M., Tanaka, I., Suga, S. ., Ogawa, Y., Tamura, N., Goto, M., Sugawara, A., Yoshimasa, T., Itoh, H., Mukoyama, M. & Nakao, K., 1995 11月, In: Clinical and Experimental Pharmacology and Physiology. 22, p. S186-S187

研究成果: Article › 査読

8 被引用数 (Scopus)

Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy: Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload

Nakagawa, O., Ogawa, Y., Itoh, H., Suga, S. I., Komatsu, Y., Kishimoto, I., Nishino, K., Yoshimasa, T. & Nakao, K., 1995 9月, In: Journal of Clinical Investigation. 96, 3, p. 1280-1287 8 p.

研究成果: Article › 査読

Open Access

571 被引用数 (Scopus)

Rapid ventricular induction of brain natriuretic peptide gene expression in experimental acute myocardial infarction

Hama, N., Itoh, H., Shirakami, G., Nakagawa, O., Suga, S. I., Ogawa, Y., Masuda, I., Nakanishi, K., Yoshimasa, T., Hashimoto, Y., Yamaguchi, M., Hori, R., Yasue, H. & Nakao, K., 1995 9月 15, In: Circulation. 92, 6, p. 1558-1564 7 p.

研究成果: Article › 査読

382 被引用数 (Scopus)

Significance of autocrine/paracrine network in renal vascular and mesangial growth

Itoh, H. & Nakao, K., 1995, In: japanese heart journal. 36, 4, p. 501 1 p.

研究成果: Article › 査読

Open Access

Structural organization and chromosomal assignment of the human prostacyclin receptor gene

Ogawa, Y., Tanaka, I., Inoue, M., Yoshitake, Y., Isse, N., Nakagawa, O., Usui, T., Itoh, H., Yoshimasa, T., Narumiya, S. & Nakao, K., 1995 5月 1, In: Genomics. 27, 1, p. 142-148 7 p.

研究成果: Article › 査読

35 被引用数 (Scopus)

Umbilical venous guanosine 3', 5'-cyclic phosphate (Cgmp) concentration increases in asphyxiated newborns1

Itoh, H., Sagawa, N., Hasegawa, M., Mori, T., Suga, S. I., Mukoyama, M., Yoshimasa, T., Itoh, H. & Nakao, K., 1995, In: Reproduction, Fertility and Development. 7, 6, p. 1515-1519 5 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

1994

A monoclonal antibody to C-type natriuretic peptide - Preparation and application to radioimmunoassay and neutralization experiment

Hama, N., Itoh, H., Suga, S., Komatsu, Y., Yoshimasa, T. & Nakao, K., 1994, In: Journal of Endocrinology. 141, 3, p. 473-479 7 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Antagonism between the vascular renin-angiotensin and natriuretic peptide systems in vascular remodelling

Itoh, H. & Nakao, K., 1994 1月 1, In: Blood Pressure, Supplement. 3, 5, p. 49-53 5 p.

研究成果: Article › 査読

23 被引用数 (Scopus)

Detection of C-type natriuretic peptide in human circulation and marked increase of plasma CNP level in septic shock patients

Hama, N., Itoh, H., Shirakami, G., Suga, S. I., Komatsu, Y., Yoshimasa, T., Tanaka, I., Mori, K. & Nakao, K., 1994 2月 14, In: Biochemical and Biophysical Research Communications. 198, 3, p. 1177-1182 6 p.

研究成果: Article › 査読

130 被引用数 (Scopus)

Expression of Biologically Active Receptors for Natriuretic Peptides in the Human Uterus during Pregnancy

Itoh, H., Sagawa, N., Hasegawa, M., Nanno, H., Kobayashi, F., Ihara, Y., Mori, T., Komatsu, Y., Suga, S. I., Yoshimasa, T., Itoh, H. & Nakao, K., 1994 1月 1, In: Biochemical and Biophysical Research Communications. 203, 1, p. 602-607 6 p.

研究成果: Article › 査読

46 被引用数 (Scopus)

Functional evidence for an apical ANP receptor in LLC-PK₁ kidney epithelial cells

Yukiya Hashimoto, H., Junko Ozaki, O., Masato Yasuhara, Y., Ryohei Hori, H., Shin-ichi Suga, S., Hiroshi Itoh, I., Kazuwa Nakao, N. & Ken-inchi Inui, I., 1994 8月 16, In: European Journal of Pharmacology: Molecular Pharmacology. 268, 3, p. 443-445 3 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Molecular biology of brain natriuretic peptide

Ogawa, Y., Itoh, H. & Nakao, K., 1994, In: japanese heart journal. 35, 4, p. 496-497 2 p.

研究成果: Article › 査読

Open Access

Molecular cloning and chromosomal assignment of the mouse C-Type natriuretic peptide (CNP) gene (NPPC): Comparison with the human CNP gene (NPPC)

Ogawa, Y., Itoh, H., Yoshitake, Y., Inoue, M., Yoshimasa, T., Serikawa, T. & Nakao, K., 1994 11月 15, In: Genomics. 24, 2, p. 383-387 5 p.

研究成果: Article › 査読

72 被引用数 (Scopus)

Molecular cloning of hamster brain and atrial natriuretic peptide cDNAs. Cardiomyopathic hamsters are useful models for brain and atrial natriuretic peptides

Tamura, N., Ogawa, Y., Itoh, H., Arai, H., Suga, S. I., Nakagawa, O., Komatsu, Y., Kishimoto, I., Takaya, K., Yoshimasa, T., Shiono, S. & Nakao, K., 1994, In: Journal of Clinical Investigation. 94, 3, p. 1059-1068 10 p.

研究成果: Article › 査読

Open Access

31 被引用数 (Scopus)

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伊藤裕