年単位の研究成果
研究成果
2020
Association of glomerular DNA damage and DNA methylation with one-year eGFR decline in IgA nephropathy
Hayashi, K., Hishikawa, A., Hashiguchi, A., Azegami, T., Yoshimoto, N., Nakamichi, R., Tokuyama, H. & Itoh, H., 2020 12 1, ： : Scientific reports. 10, 1, 237.研究成果: Article
公開
DNA damage and expression of DNA methylation modulators in urine-derived cells of patients with hypertension and diabetes
Hishikawa, A., Hayashi, K., Yoshimoto, N., Nakamichi, R., Homma, K. & Itoh, H., 2020 2 25, ： : Scientific reports. 10, 1, 1 p.研究成果: Article
公開
2019
Decreased KAT5 Expression Impairs DNA Repair and Induces Altered DNA Methylation in Kidney Podocytes
Hishikawa, A., Hayashi, K., Abe, T., Kaneko, M., Yokoi, H., Azegami, T., Nakamura, M., Yoshimoto, N., Kanda, T., Sakamaki, Y. & Itoh, H., 2019 1 29, ： : Cell Reports. 26, 5, p. 1318-1332.e4研究成果: Article
2
引用
（Scopus）
2018
Intranasal vaccination against angiotensin II type 1 receptor and pneumococcal surface protein A attenuates hypertension and pneumococcal infection in rodents
Azegami, T., Yuki, Y., Hayashi, K., Hishikawa, A., Sawada, S. I., Ishige, K., Akiyoshi, K., Kiyono, H. & Itoh, H., 2018 2 1, ： : Journal of Hypertension. 36, 2, p. 387-394 8 p.研究成果: Article
11
引用
（Scopus）
Pre-emptive medicine for hypertension and its prospects
Itoh, H., Hayashi, K. & Miyashita, K., 2018 1 1, (Accepted/In press) ： : Hypertension Research.研究成果: Article
1
引用
（Scopus）
2017
Association of kidney dysfunction with asymptomatic cerebrovascular abnormalities in a Japanese population with health checkups
Hayashi, K., Takayama, M., Kanda, T., Kashiwagi, K., Hishikawa, A., Iwao, Y. & Itoh, H., 2017, ： : Circulation Journal. 81, 8, p. 1191-1197 7 p.研究成果: Article
3
引用
（Scopus）
Investigation of metabolic factors associated with eGFR decline over 1 year in a Japanese population without CKD
Hayashi, K., Takayama, M., Abe, T., Kanda, T., Hirose, H., Shimizu, R., Shiomi, E., Iwao, Y. & Itoh, H., 2017, ： : Journal of Atherosclerosis and Thrombosis. 24, 8, p. 863-875 13 p.研究成果: Article
8
引用
（Scopus）
2015
Renin-angiotensin blockade resets podocyte epigenome through Kruppel-like Factor 4 and attenuates proteinuria
Hayashi, K., Sasamura, H., Nakamura, M., Sakamaki, Y., Azegami, T., Oguchi, H., Tokuyama, H., Wakino, S., Hayashi, K. & Itoh, H., 2015 10 3, ： : Kidney International. 88, 4, p. 745-753 9 p.研究成果: Article
28
引用
（Scopus）
Therapeutic effect of RAS inhibitors on epigenetic changes in life-style related diseases
Hayashi, K. & Itoh, H., 2015 11 1, ： : Nihon rinsho. Japanese journal of clinical medicine. 73, 11, p. 1933-1938 6 p.研究成果: Article
2014
KLF4-dependent epigenetic remodeling modulates podocyte phenotypes and attenuates proteinuria
Hayashi, K., Sasamura, H., Nakamura, M., Azegami, T., Oguchi, H., Sakamaki, Y. & Itoh, H., 2014 6 2, ： : Journal of Clinical Investigation. 124, 6, p. 2523-2537 15 p.研究成果: Article
60
引用
（Scopus）
Renal arteriolar injury by salt intake contributes to salt memory for the development of hypertension
Oguchi, H., Sasamura, H., Shinoda, K., Morita, S., Kono, H., Nakagawa, K., Ishiguro, K., Hayashi, K., Nakamura, M., Azegami, T., Oya, M. & Itoh, H., 2014, ： : Hypertension. 64, 4, p. 784-791 8 p.研究成果: Article
5
引用
（Scopus）
Transcription Factors and Epigenetic Modulation: Its Therapeutic Implication in Chronic Kidney Disease
Hayashi, K. & Itoh, H., 2014 12 11, (Accepted/In press) ： : Archivum Immunologiae et Therapiae Experimentalis.研究成果: Article
5
引用
（Scopus）
2012
Regression of atherosclerosis in apolipoprotein E-deficient mice is feasible using high-dose angiotensin receptor blocker, candesartan
Hayashi, K., Sasamura, H., Azegami, T. & Itoh, H., 2012, ： : Journal of Atherosclerosis and Thrombosis. 19, 8, p. 736-746 11 p.研究成果: Article
15
引用
（Scopus）
Vaccination against the angiotensin type 1 receptor for the prevention of L-NAME-induced nephropathy
Azegami, T., Sasamura, H., Hayashi, K. & Itoh, H., 2012 5, ： : Hypertension Research. 35, 5, p. 492-499 8 p.研究成果: Article
21
引用
（Scopus）
2011
Use of serum and urine metabolome analysis for the detection of metabolic changes in patients with stage 1-2 chronic kidney disease
Hayashi, K., Sasamura, H., Hishiki, T., Suematsu, M., Ikeda, S., Soga, T. & Itoh, H., 2011, ： : Nephro-Urology Monthly. 3, 3, p. 164-171 8 p.研究成果: Article
20
引用
（Scopus）
2010
Absence of gelatinase (MMP-9) or collagenase (MMP-13) attenuates adriamycin-Induced albuminuria and glomerulosclerosis
Sakamaki, Y., Sasamura, H., Hayashi, K., Ishiguro, K., Takaishi, H., Okada, Y., D'Armiento, J. M., Saruta, T. & Itoh, H., 2010 6, ： : Nephron - Experimental Nephrology. 115, 2研究成果: Article
14
引用
（Scopus）
Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2
Hayashi, K., Sasamura, H., Ishiguro, K., Sakamaki, Y., Azegami, T. & Itoh, H., 2010 7, ： : Kidney International. 78, 1, p. 69-78 10 p.研究成果: Article
35
引用
（Scopus）
2009
Activation of dendritic-like cells and neural stem/progenitor cells in injured spinal cord by GM-CSF
Hayashi, K., Ota, S., Kawakami, Y. & Toda, M., 2009 5, ： : Neuroscience Research. 64, 1, p. 96-103 8 p.研究成果: Article
31
引用
（Scopus）
Prevention and regression of hypertension: Role of renal microvascular protection
Sasamura, H., Hayashi, K., Ishiguro, K., Nakaya, H., Saruta, T. & Itoh, H., 2009, ： : Hypertension Research. 32, 8, p. 658-664 7 p.研究成果: Article
15
引用
（Scopus）
"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension
Ishiguro, K., Hayashi, K., Sasamura, H., Sakamaki, Y. & Itoh, H., 2009 1, ： : Hypertension. 53, 1, p. 83-89 7 p.研究成果: Article
22
引用
（Scopus）
2008
Differential effects of transient treatment of spontaneously hypertensive rats with various antihypertensive agents on the subsequent development of diabetic nephropathy
Ishiguro, K., Sasamura, H., Sakamaki, Y., Hayashi, K., Saruta, T. & Itoh, H., 2008 6, ： : Nephron - Experimental Nephrology. 109, 1研究成果: Article
7
引用
（Scopus）