年別の研究成果
年別の研究成果
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β-Carboline-Carbohydrate hybrids: Molecular design, chemical synthesis and evaluation of novel DNA photocleavers
Toshima, K., Okuno, Y., Nakajima, Y. & Matsumura, S., 2002 2月 25, In: Bioorganic and Medicinal Chemistry Letters. 12, 4, p. 671-673 3 p.研究成果: Article › 査読
36 被引用数 (Scopus) -
Vacuolar-type H+-ATPase inhibitory activity of synthetic analogues of the concanamycins: Is the hydrogen bond network involving the lactone carbonyl, the hemiacetal hydroxy group, and the C-19 hydroxy group essential for the biological activity of the concanamycins?
Yoshimoto, Y., Jyojima, T., Arita, T., Ueda, M., Imoto, M., Matsumura, S. & Toshima, K., 2002 12月, In: Bioorganic and Medicinal Chemistry Letters. 12, 24, p. 3525-3528 4 p.研究成果: Article › 査読
10 被引用数 (Scopus) -
Two-step synthesis of C-glycosyl juglones from unprotected sugars: A novel approach to angucycline antibiotics
Matsuo, G., Matsumura, S. & Toshima, K., 1996, In: Chemical Communications. 18, p. 2173-2174 2 p.研究成果: Article › 査読
15 被引用数 (Scopus) -
Transformation of biodegradable polyesters into cyclic oligomers under continuous flow using an enzyme-packed column
Osanai, Y., Toshima, K. & Matsumura, S., 2004 11月 20, In: Macromolecular Bioscience. 4, 10, p. 936-942 7 p.研究成果: Article › 査読
18 被引用数 (Scopus) -
Toward the total synthesis of vineomycin B2: application of an efficient glycosylation methodology using 2,3-unsaturated sugars
Sasaki, K., Matsumura, S. & Toshima, K., 2007 9月 24, In: Tetrahedron Letters. 48, 39, p. 6982-6986 5 p.研究成果: Article › 査読
15 被引用数 (Scopus) -
Total synthesis of vineomycin B2
Kusumi, S., Tomono, S., Okuzawa, S., Kaneko, E., Ueda, T., Sasaki, K., Takahashi, D. & Toshima, K., 2013 10月 23, In: Journal of the American Chemical Society. 135, 42, p. 15909-15912 4 p.研究成果: Article › 査読
23 被引用数 (Scopus) -
Total synthesis of urdamycinone B via C-glycosidation of an unprotected sugar and Diels-Alder reaction of C-glycosyl juglone
Matsuo, G., Miki, Y., Nakata, M., Matsumura, S. & Toshima, K., 1996, In: Chemical Communications. 2, p. 225-226 2 p.研究成果: Article › 査読
37 被引用数 (Scopus) -
Total synthesis of the trisaccharide of olivomycin A
Toshima, K., Nozaki, Y., Nakata, M., Tatsuta, K. & Kinoshita, M., 1993 9月 3, In: Tetrahedron Letters. 34, 36, p. 5761-5764 4 p.研究成果: Article › 査読
9 被引用数 (Scopus) -
Total Synthesis of Terpioside B
Inaba, K., Endo, M., Iibuchi, N., Takahashi, D. & Toshima, K., 2020 8月 12, In: Chemistry - A European Journal. 26, 45, p. 10222-10225 4 p.研究成果: Article › 査読
3 被引用数 (Scopus) -
Total synthesis of incednam, the aglycon of incednine
Ohtani, T., Tsukamoto, S., Kanda, H., Misawa, K., Urakawa, Y., Fujimaki, T., Imoto, M., Takahashi, Y., Takahashi, D. & Toshima, K., 2010 11月 5, In: Organic Letters. 12, 21, p. 5068-5071 4 p.研究成果: Article › 査読
19 被引用数 (Scopus) -
Total synthesis of elaiophylin (azalomycin B)
Toshima, K., Tatsuta, K. & Kinoshita, M., 1986, In: Tetrahedron Letters. 27, 39, p. 4741-4744 4 p.研究成果: Article › 査読
43 被引用数 (Scopus) -
Total synthesis of elaiophylin (azalomycin B)
Toshima, K., Tatsuta, K. & Kinoshita, M., 1988 1月 1, In: Bulletin of the Chemical Society of Japan. 61, 7, p. 2369-2381 13 p.研究成果: Article › 査読
Open Access64 被引用数 (Scopus) -
Total synthesis of C-glycosylangucycline, urdamycinone B, using an unprotected sugar
Matsuo, G., Miki, Y., Nakata, M., Matsumura, S. & Toshima, K., 1999 9月 17, In: Journal of Organic Chemistry. 64, 19, p. 7101-7106 6 p.研究成果: Article › 査読
46 被引用数 (Scopus) -
Total synthesis of bafilomycin A1. 2. The assemblage and completion of the synthesis
Toshima, K., Yamaguchi, H., Jyojima, T., Noguchi, Y., Nakata, M. & Matsumura, S., 1996 2月 12, In: Tetrahedron Letters. 37, 7, p. 1073-1076 4 p.研究成果: Article › 査読
54 被引用数 (Scopus) -
Total synthesis of bafilomycin A1. 1. Syntheses of the C5-C11, C12-C17 and C18-C25 segments
Toshima, K., Jyojima, T., Yamaguchi, H., Murase, H., Yoshida, T., Matsumura, S. & Nakata, M., 1996 2月 12, In: Tetrahedron Letters. 37, 7, p. 1069-1072 4 p.研究成果: Article › 査読
44 被引用数 (Scopus) -
Total Synthesis of Bafilomycin A1
Toshima, K., Jyojima, T., Yamaguchi, H., Noguchi, Y., Yoshida, T., Murase, H., Nakata, M. & Matsumura, S., 1997, In: Journal of Organic Chemistry. 62, 10, p. 3263-3270 8 p.研究成果: Article › 査読
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Total synthesis of bafilomycin A1
Toshima, K., Jyojima, T., Yamaguchi, H., Noguchi, Y., Yoshida, T., Murase, H., Nakata, M. & Matsumura, S., 1997 1月 1, In: Journal of Organic Chemistry. 62, 10, p. 3271-3284 14 p.研究成果: Article › 査読
76 被引用数 (Scopus) -
Total Synthesis of Aquayamycin
Kusumi, S., Nakayama, H., Kobayashi, T., Kuriki, H., Matsumoto, Y., Takahashi, D. & Toshima, K., 2016 12月 23, In: Chemistry - A European Journal. 22, 52, p. 18733-18736 4 p.研究成果: Article › 査読
11 被引用数 (Scopus) -
Total Synthesis and Structure-Activity Relationship Study of Vineomycin A1
Matsumoto, Y., Kuriki, H., Kitamura, T., Takahashi, D. & Toshima, K., 2019 1月 1, In: Journal of Organic Chemistry.研究成果: Article › 査読
1 被引用数 (Scopus) -
Total syntheses of glucosidase inhibitors, cyclophellitols
Tatsuta, K., Niwata, Y., Umezawa, K., Toshima, K. & Nakata, M., 1991 12月 30, In: Carbohydrate Research. 222, C, p. 189-203 15 p.研究成果: Article › 査読
51 被引用数 (Scopus) -
The use of organophotoacids for deprotection reactions in organic synthesis
Nishikubo, Y., Kanzaki, S., Matsumura, S. & Toshima, K., 2006 11月 13, In: Tetrahedron Letters. 47, 46, p. 8125-8128 4 p.研究成果: Article › 査読
12 被引用数 (Scopus) -
The use of 2,6-anhydro-2-thio sugar for a highly stereocontrolled glycosylation: A novel strategy for synthesis of 2,6-dideoxy-α-glycosides
Toshima, K., Mukaiyama, S., Ishiyama, T. & Tatsuta, K., 1990, In: Tetrahedron Letters. 31, 23, p. 3339-3342 4 p.研究成果: Article › 査読
26 被引用数 (Scopus) -
The use of 2,6-anhydro-2-thio glycopyranosyl fluoride for a highly α-stereoselective glycosylation
Toshima, K., Mukaiyama, S., Ishiyama, T. & Tatsuta, K., 1990, In: Tetrahedron Letters. 31, 44, p. 6361-6362 2 p.研究成果: Article › 査読
19 被引用数 (Scopus) -
The significant effect of the carbohydrate structures on the DNA photocleavage of the quinoxaline-carbohydrate hybrids
Toshima, K., Ozawa, T., Kimura, T. & Matsumura, S., 2004 6月 7, In: Bioorganic and Medicinal Chemistry Letters. 14, 11, p. 2777-2779 3 p.研究成果: Article › 査読
30 被引用数 (Scopus) -
The selective distinction of diethylisopropylsilyl ether in hydrogenolysis
Toshima, K., Yanagawa, K., Mukaiyama, S. & Tatsuta, K., 1990, In: Tetrahedron Letters. 31, 46, p. 6697-6698 2 p.研究成果: Article › 査読
26 被引用数 (Scopus) -
The novel selenium mediated aromatization of a 1,6-diyn-3-ene system related to neocarzinostatin chromophore
Toshima, K., Ohta, K., Ohtake, T. & Tatsuta, K., 1991 12月 1, In: Journal of the Chemical Society, Chemical Communications. 10, p. 694-695 2 p.研究成果: Article › 査読
17 被引用数 (Scopus) -
The manners of aromatization of a new 10-membered ring 1,6-diyn-3-ene system under basic conditions
Toshima, K., Ohta, K., Ohtake, T. & Tatsuta, K., 1991 1月 14, In: Tetrahedron Letters. 32, 3, p. 391-394 4 p.研究成果: Article › 査読
39 被引用数 (Scopus) -
The first total synthesis of concanamycin F (concanolide A)
Toshima, K., Jyojima, T., Miyamoto, N., Katohno, M., Nakata, M. & Matsumura, S., 2001 3月 9, In: Journal of Organic Chemistry. 66, 5, p. 1708-1715 8 p.研究成果: Article › 査読
59 被引用数 (Scopus) -
The education system for chemical biology in Japanese universities.
Osada, H., Hagiwara, M., Toshima, K. & Imoto, M., 2006 9月 19, In: ACS chemical biology. 1, 8, p. 492-494 3 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
The direct and one-pot transformation of xylan into the biodegradable surfactants, alkyl xylosides, is aided by an ionic liquid
Sekine, M., Kimura, T., Katayama, Y., Takahashi, D. & Toshima, K., 2013 11月 21, In: RSC Advances. 3, 43, p. 19756-19759 4 p.研究成果: Article › 査読
16 被引用数 (Scopus) -
The diethylisopropylsilyl group: A new protecting group for alcohols
Toshima, K., Mukaiyama, S., Kinoshita, M. & Tatsuta, K., 1989, In: Tetrahedron Letters. 30, 46, p. 6413-6416 4 p.研究成果: Article › 査読
37 被引用数 (Scopus) -
Target-selective photo-degradation of verotoxin-1 and reduction of its cytotoxicity to Vero cells using porphyrin–globotriose hybrids
Okochi, A., Tanimoto, S., Takahashi, D. & Toshima, K., 2013 6月 11, In: Chemical Communications. 49, 54, p. 6027-6029 3 p.研究成果: Article › 査読
8 被引用数 (Scopus) -
Target-selective photodegradation of oligosaccharides by a fullerene-boronic acid hybrid upon visible light irradiation
Takahashi, D., Hirono, S. & Toshima, K., 2011 11月 14, In: Chemical Communications. 47, 42, p. 11712-11714 3 p.研究成果: Article › 査読
12 被引用数 (Scopus) -
Target-selective photo-degradation of HIV-1 protease by a fullerene-sugar hybrid
Tanimoto, S., Sakai, S., Matsumura, S., Takahashi, D. & Toshima, K., 2008, In: Chemical Communications. 44, p. 5767-5769 3 p.研究成果: Article › 査読
55 被引用数 (Scopus) -
Target-selective photodegradation of HIV-1 protease and inhibition of HIV-1 replication in living cells by designed fullerene-sugar hybrids
Tanimoto, S., Sakai, S., Kudo, E., Okada, S., Matsumura, S., Takahashi, D. & Toshima, K., 2012 5月, In: Chemistry - An Asian Journal. 7, 5, p. 911-914 4 p.研究成果: Article › 査読
22 被引用数 (Scopus) -
Target-selective photo-degradation of a sialyl Lewis a (sLea) conjugate and photo-cytotoxicity against sLea positive cancer cells using an anthraquinone-antibody hybrid
Takahashi, D., Nagao, T., Sotokawa, S. & Toshima, K., 2016, In: MedChemComm. 7, 6, p. 1224-1228 5 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
Target-selective photo-degradation of AFP-L3 and selective photo-cytotoxicity against HuH-7 hepatocarcinoma cells using an anthraquinone-PhoSL hybrid
Okuyama, M., Ueno, H., Kobayashi, Y., Kawagishi, H., Takahashi, D. & Toshima, K., 2016, In: Chemical Communications. 52, 10, p. 2169-2172 4 p.研究成果: Article › 査読
10 被引用数 (Scopus) -
Target-Selective Fluorescence Imaging and Photocytotoxicity against H2O2 High-Expressing Cancer Cells Using a Photoactivatable Theranostic Agent
Takagi, R., Takeda, A., Takahashi, D. & Toshima, K., 2017 10月 18, In: Chemistry - An Asian Journal. 12, 20, p. 2656-2659 4 p.研究成果: Article › 査読
8 被引用数 (Scopus) -
Target-selective degradation of proteins by porphyrins upon visible photo-irradiation
Tanimoto, S., Matsumura, S. & Toshima, K., 2008, In: Chemical Communications. 31, p. 3678-3680 3 p.研究成果: Article › 査読
26 被引用数 (Scopus) -
Target-selective degradation of proteins by a light-activated 2-phenylquinoline-estradiol hybrid
Suzuki, A., Tsumura, K., Tsuzuki, T., Matsumura, S. & Toshima, K., 2007 1月 1, In: Chemical Communications. 41, p. 4260-4262 3 p.研究成果: Article › 査読
17 被引用数 (Scopus) -
Target-selective degradation of oligosaccharides by a light-activated small-molecule-lectin hybrid
Ishii, M., Matsumura, S. & Toshima, K., 2007 11月 21, In: Angewandte Chemie - International Edition. 46, 44, p. 8396-8399 4 p.研究成果: Article › 査読
24 被引用数 (Scopus) -
Systematic synthesis of sulfated oligofucosides and their effect on breast cancer MCF-7 cells
Arafuka, S., Koshiba, N., Takahashi, D. & Toshima, K., 2014 7月 31, In: Chemical Communications. 50, 69, p. 9831-9834 4 p.研究成果: Article › 査読
15 被引用数 (Scopus) -
Systematic synthesis of low-molecular weight fucoidan derivatives and their effect on cancer cells
Kasai, A., Arafuka, S., Koshiba, N., Takahashi, D. & Toshima, K., 2015, In: Organic and Biomolecular Chemistry. 13, 42, p. 10556-10568 13 p.研究成果: Article › 査読
43 被引用数 (Scopus) -
Systematic and Stereoselective Total Synthesis of Mannosylerythritol Lipids and Evaluation of Their Antibacterial Activity
Nashida, J., Nishi, N., Takahashi, Y., Hayashi, C., Igarashi, M., Takahashi, D. & Toshima, K., 2018 7月 6, In: Journal of Organic Chemistry. 83, 13, p. 7281-7289 9 p.研究成果: Article › 査読
23 被引用数 (Scopus) -
Synthetic studies on concanamycin A: Total synthesis of concanolide A (concanamycin F)
Jyojima, T., Miyamoto, N., Katohno, M., Nakata, M., Matsumura, S. & Toshima, K., 1998 8月 13, In: Tetrahedron Letters. 39, 33, p. 6007-6010 4 p.研究成果: Article › 査読
26 被引用数 (Scopus) -
Synthetic studies on concanamycin A: Synthesis of the C5~C13 and C20~C28 segments
Jyojima, T., Katohno, M., Miyamoto, N., Nakata, M., Matsumura, S. & Toshima, K., 1998 8月 13, In: Tetrahedron Letters. 39, 33, p. 6003-6006 4 p.研究成果: Article › 査読
21 被引用数 (Scopus) -
Synthetic studies on apoptolidin: Synthesis of the C12-C28 fragment via a highly stereoselective aldol reaction
Abe, K., Kato, K., Arai, T., Rahim, M. A., Sultana, I., Matsumura, S. & Toshima, K., 2004 11月 22, In: Tetrahedron Letters. 45, 48, p. 8849-8853 5 p.研究成果: Article › 査読
21 被引用数 (Scopus) -
Synthetic studies on apoptolidin: Synthesis of the C1-C21 macrolide fragment
Toshima, K., Arita, T., Kato, K., Tanaka, D. & Matsumura, S., 2001 12月 10, In: Tetrahedron Letters. 42, 50, p. 8873-8876 4 p.研究成果: Article › 査読
49 被引用数 (Scopus) -
Synthetic studies of rifamycins. VIII. An improved practical synthesis of the ansa-chain compounds for the rifamycin W synthesis
Nakata, M., Toshima, K., Kai, T. & Kinoshita, M., 1985 1月 1, In: Bulletin of the Chemical Society of Japan. 58, 12, p. 3457-3464 8 p.研究成果: Article › 査読
Open Access21 被引用数 (Scopus) -
Synthetic studies of incednine: synthesis of C1-C13 pentaenoic acid segment
Ohtani, T., Kanda, H., Misawa, K., Urakawa, Y. & Toshima, K., 2009 5月 13, In: Tetrahedron Letters. 50, 19, p. 2270-2273 4 p.研究成果: Article › 査読
6 被引用数 (Scopus)