Kazunobu Toshima

1996

Novel and artificial enediyne DNA cleaving molecules: molecular design, chemical synthesis, and evaluation

Toshima, K., Nakata, M. & Matsumura, S., 1996, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 54, 6, p. 503-513 11 p.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Novel and Artificial Enediyne DNA Cleaving Molecules: Molecular Design, Chemical Synthesis, and Evaluation

Toshima, K., Nakata, M. & Matsumura, S., 1996 12月 1, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 54, 6, p. 51-61 11 p.

研究成果: Article › 査読

Novel designed enediynes: Molecular design, chemical synthesis, mode of cycloaromatization and guanine-specific DNA cleavage

Toshima, K., Ohta, K., Kano, T., Nakamura, T., Nakata, M., Kinoshita, M. & Matsumura, S., 1996 1月, In: Bioorganic and Medicinal Chemistry. 4, 1, p. 105-113 9 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Preparation of poly(β-malic acid) by enzymatic ring-opening polymerization of benzyl β-malolactonate

Matsumura, S., Beppu, H., Nakamura, K., Osanai, S. & Toshima, K., 1996, In: Chemistry Letters. 9, p. 795-796 2 p.

研究成果: Article › 査読

53 被引用数 (Scopus)

Total synthesis of bafilomycin A₁. 1. Syntheses of the C5-C11, C12-C17 and C18-C25 segments

Toshima, K., Jyojima, T., Yamaguchi, H., Murase, H., Yoshida, T., Matsumura, S. & Nakata, M., 1996 2月 12, In: Tetrahedron Letters. 37, 7, p. 1069-1072 4 p.

研究成果: Article › 査読

44 被引用数 (Scopus)

Total synthesis of bafilomycin A₁. 2. The assemblage and completion of the synthesis

Toshima, K., Yamaguchi, H., Jyojima, T., Noguchi, Y., Nakata, M. & Matsumura, S., 1996 2月 12, In: Tetrahedron Letters. 37, 7, p. 1073-1076 4 p.

研究成果: Article › 査読

54 被引用数 (Scopus)

Total synthesis of urdamycinone B via C-glycosidation of an unprotected sugar and Diels-Alder reaction of C-glycosyl juglone

Matsuo, G., Miki, Y., Nakata, M., Matsumura, S. & Toshima, K., 1996, In: Chemical Communications. 2, p. 225-226 2 p.

研究成果: Article › 査読

37 被引用数 (Scopus)

Two-step synthesis of C-glycosyl juglones from unprotected sugars: A novel approach to angucycline antibiotics

Matsuo, G., Matsumura, S. & Toshima, K., 1996, In: Chemical Communications. 18, p. 2173-2174 2 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

1995

Application of Highly Stereocontrolled Glycosidations Employing 2,6-Anhydro-2-thio Sugars to the Syntheses of Erythromycin A and Olivomycin A Trisaccharide

Toshima, K., Nozaki, Y., Mukaiyama, S., Tamai, T., Nakata, M., Tatsuta, K. & Kinoshita, M., 1995 4月, In: Journal of the American Chemical Society. 117, 13, p. 3717-3727 11 p.

研究成果: Article › 査読

52 被引用数 (Scopus)

Molecular Design, Chemical Synthesis, and Study of Novel Enediyne—Sulfide Systems Related to the Neocarzinostatin Chromophore

Toshima, K., Ohta, K., Ohashi, A., Nakamura, T., Nakata, M., Tatsuta, K. & Matsumura, S., 1995 5月, In: Journal of the American Chemical Society. 117, 17, p. 4822-4831 10 p.

研究成果: Article › 査読

45 被引用数 (Scopus)

Molecular design of biodegradable functional polymers, 4 Poly(vinyl alcohol) block as biodegradable segment

Matsumura, S., Shimura, Y., Toshima, K., Tsuji, M. & Hatanaka, T., 1995 11月, In: Macromolecular Chemistry and Physics. 196, 11, p. 3437-3445 9 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Novel Dienediyne Systems Related to the Neocarzinostatin Chromophore: Molecular Design, Chemical Synthesis, and Evaluation

Toshima, K., Ohta, K., Yanagawa, K., Kano, T., Nakata, M., Kinoshita, M. & Matsumura, S., 1995, In: Journal of the American Chemical Society. 117, 44, p. 10825-10831 7 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

Practical Glycosidation Method of Glycals Using Montmorillonite K-10 as an Environmentally Acceptable and Inexpensive Industrial Catalyst

Toshima, K., Ishizuka, T., Matsuo, G. & Nakata, M., 1995 4月, In: Synlett. 1995, 4, p. 306-308 3 p.

研究成果: Article › 査読

78 被引用数 (Scopus)

1994

Allyl C-glycosidations of totally unprotected glycals and allyltrimethylsilane with trimethylsilyl trifluoromethanesulfonate (TMSOTf)

Toshima, K., Ishizuka, T., Matsuo, G. & Nakata, M., 1994 8月 1, In: Tetrahedron Letters. 35, 31, p. 5673-5676 4 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

An imrpoved practical method for synthesis of aryl C-glycosides from unprotected methyl glycosides and 1-hydroxy sugars

Toshima, K., Matsuo, G. & Nakata, M., 1994 12月 1, In: Journal of the Chemical Society, Chemical Communications. 8, p. 997-998 2 p.

研究成果: Article › 査読

31 被引用数 (Scopus)

A novel monocyclic dienediyne system: Synthesis and mode of aromatization

Toshima, K., Yanagawa, K., Ohta, K., Kano, T. & Nakata, M., 1994 3月 7, In: Tetrahedron Letters. 35, 10, p. 1573-1576 4 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Builder performance in detergent formulations and biodegradability of partially dicarboxylated amylopectin

Matsumura, S., Aoki, K. & Toshima, K., 1994 7月 1, In: Journal of the American Oil Chemists' Society. 71, 7, p. 749-755 7 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Design, cycloaromatization and guanine-selective DNA cleavage of novel enediynes

Toshima, K., Ohta, K., Kano, T., Nakamura, T., Nakata, M. & Matsumura, S., 1994 12月 1, In: Journal of the Chemical Society, Chemical Communications. 19, p. 2295-2296 2 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Microbial production of (2 R, 4 R)-2,4-pentanediol by enatioselective reduction of acetylacetone and stereoinversion of 2,4-pentanediol

Matsumura, S., Kawai, Y., Takahashi, Y. & Toshima, K., 1994 5月 1, In: Biotechnology Letters. 16, 5, p. 485-490 6 p.

研究成果: Article › 査読

20 被引用数 (Scopus)

Novel Glycosidation Method Using 2,6-Anhydro-2-thio Sugars for Stereocontrolled Synthesis of 2,6-Dideoxy-α- and -β-glycosides

Toshima, K., Mukaiyama, S., Nozaki, Y., Inokuchi, H., Nakata, M. & Tatsuta, K., 1994 10月 1, In: Journal of the American Chemical Society. 116, 20, p. 9042-9051 10 p.

研究成果: Article › 査読

37 被引用数 (Scopus)

1993

A family of cyclophellitol analogs: Synthesis and evaluation

Nakata, M., Chong, C., Niwata, Y., Toshima, K. & Tatsuta, K., 1993 1月 1, In: Journal of Antibiotics. 46, 12, p. 1919-1922 4 p.

研究成果: Article › 査読

Open Access

24 被引用数 (Scopus)

A new entry for the controlled synthesis of 2,6-dideoxy oligosaccharides

Toshima, K., Nozaki, Y., Inokuchi, H., Nakata, M., Tatsuta, K. & Kinoshita, M., 1993 3月 5, In: Tetrahedron Letters. 34, 10, p. 1611-1614 4 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Cycloaromatization and DNA cleavage of novel enyne-allene systems

Toshima, K., Ohta, K., Ohtsuka, A., Matsumura, S. & Nakata, M., 1993 12月 1, In: Journal of the Chemical Society, Chemical Communications. 18, p. 1406-1407 2 p.

研究成果: Article › 査読

36 被引用数 (Scopus)

Design, synthesis and DNA cleaving profiles of hybrids containing the novel enediyne and naturally occurring DNA intercalates

Toshima, K., Ohta, K., Ohashi, A., Nakamura, T., Nakata, M. & Matsumura, S., 1993 12月 1, In: Journal of the Chemical Society, Chemical Communications. 19, p. 1525-1527 3 p.

研究成果: Article › 査読

23 被引用数 (Scopus)

Glycosidation of glycals by 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) as a catalytic promoter

Toshima, K., Ishizuka, T., Matsuo, G., Nakata, M. & Kinoshita, M., 1993 12月 1, In: Journal of the Chemical Society, Chemical Communications. 8, p. 704-706 3 p.

研究成果: Article › 査読

86 被引用数 (Scopus)

Recent Progress in O-Glycosylation Methods and Its Application to Natural Products Synthesis

Toshima, K. & Tatsuta, K., 1993, In: Chemical Reviews. 93, 4, p. 1503-1531 29 p.

研究成果: Article › 査読

1183 被引用数 (Scopus)

Total synthesis of the trisaccharide of olivomycin A

Toshima, K., Nozaki, Y., Nakata, M., Tatsuta, K. & Kinoshita, M., 1993 9月 3, In: Tetrahedron Letters. 34, 36, p. 5761-5764 4 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

1992

C-arylglycosylation of unprotected free sugar

Toshima, K., Matsuo, G., Ishizuka, T., Nakata, M. & Kinoshita, M., 1992 12月 1, In: Journal of the Chemical Society, Chemical Communications. 22, p. 1641-1642 2 p.

研究成果: Article › 査読

32 被引用数 (Scopus)

Design and synthesis of 1-thia-3,8-diyn-5-ene systems with DNA-cleaving properties related to the neocarzinostatin chromophore

Toshima, K., Ohta, K., Ohashi, A., Ohtsuka, A., Nakata, M. & Tatsuta, K., 1992 12月 1, In: Journal of the Chemical Society, Chemical Communications. 18, p. 1306-1308 3 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Efficient C-arylglycosylation of 1-O-methyl sugar by novel use of TMSOTf-AgClO₄ catalyst system

Toshima, K., Matsuo, G. & Tatsuta, K., 1992 4月 14, In: Tetrahedron Letters. 33, 16, p. 2175-2178 4 p.

研究成果: Article › 査読

32 被引用数 (Scopus)

Highly Stereocontrolled Synthesis of 2,6-Dideoxy Sugars and its Application to Synthesis of Natural Products

Toshima, K. & Tatsuta, K., 1992, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 50, 4, p. 303-315 13 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Highly β-stereoselective glycosylation by use of 1-O-acetyl-2,6-anhydro-2-thio glycosyl donor for synthesis of 2,6-dideoxy-β-glycosides

Toshima, K., Nozaki, Y., Mukaiyama, S. & Tatsuta, K., 1992 3月 10, In: Tetrahedron Letters. 33, 11, p. 1491-1494 4 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

1991

Application of efficient glycosylation of 2,6-anhydro-2-thio sugar to the total synthesis of erythromycin A

Toshima, K., Mukaiyama, S., Yoshida, T., Tamai, T. & Tatsuta, K., 1991 10月 21, In: Tetrahedron Letters. 32, 43, p. 6155-6158 4 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

De Novo highly stereocontrolled synthesis of 2,6-dideoxy-C-3-branched carbohydrates by use of 2,6-anhydro-2-thio sugar: l-cladinose and its C-3 epimer

Toshima, K., Yoshida, T., Mukaiyama, S. & Tatsuta, K., 1991 8月 12, In: Tetrahedron Letters. 32, 33, p. 4139-4142 4 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

De novo highly stereocontrolled synthesis of 2,6-dideoxy sugars by use of 2,6-anhydro-2-thio sugars

Toshima, K., Yoshida, T., Mukaiyama, S. & Tatsuta, K., 1991 12月 30, In: Carbohydrate Research. 222, C, p. 173-188 16 p.

研究成果: Article › 査読

25 被引用数 (Scopus)

Enantiospecific synthesis and biological evaluation of 1,6-epi-cy-clophellitol

Tatsuta, K., Niwata, Y., Umezawa, K., Toshima, K. & Nakata, M., 1991 1月 1, In: The Journal of Antibiotics. 44, 4, p. 456-458 3 p.

研究成果: Article › 査読

Open Access

37 被引用数 (Scopus)

Highly stereoselective glycosylation by conformational assistance of glycosyl donor

Toshima, K., Nozaki, Y. & Tatsuta, K., 1991 11月 18, In: Tetrahedron Letters. 32, 47, p. 6887-6890 4 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Syntheses and Enzyme Inhibiting Activities of Cyclophellitol Analogs

Tatsuta, K., Niwata, Y., Umezawa, K., Toshima, K. & Nakata, M., 1991 1月 1, In: Journal of Antibiotics. 44, 8, p. 912-914 3 p.

研究成果: Article › 査読

Open Access

40 被引用数 (Scopus)

The manners of aromatization of a new 10-membered ring 1,6-diyn-3-ene system under basic conditions

Toshima, K., Ohta, K., Ohtake, T. & Tatsuta, K., 1991 1月 14, In: Tetrahedron Letters. 32, 3, p. 391-394 4 p.

研究成果: Article › 査読

39 被引用数 (Scopus)

The novel selenium mediated aromatization of a 1,6-diyn-3-ene system related to neocarzinostatin chromophore

Toshima, K., Ohta, K., Ohtake, T. & Tatsuta, K., 1991 12月 1, In: Journal of the Chemical Society, Chemical Communications. 10, p. 694-695 2 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

Total syntheses of glucosidase inhibitors, cyclophellitols

Tatsuta, K., Niwata, Y., Umezawa, K., Toshima, K. & Nakata, M., 1991 12月 30, In: Carbohydrate Research. 222, C, p. 189-203 15 p.

研究成果: Article › 査読

51 被引用数 (Scopus)

1990

Enantiospecific Total Synthesis of a β-Glucosidase Inhibitor, Cyclophellitol

Tatsuta, K., Niwata, Y., Umezawa, K., Toshima, K. & Nakata, M., 1990, In: Tetrahedron Letters. 31, 8, p. 1171-1172 2 p.

研究成果: Article › 査読

76 被引用数 (Scopus)

The selective distinction of diethylisopropylsilyl ether in hydrogenolysis

Toshima, K., Yanagawa, K., Mukaiyama, S. & Tatsuta, K., 1990, In: Tetrahedron Letters. 31, 46, p. 6697-6698 2 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

The use of 2,6-anhydro-2-thio glycopyranosyl fluoride for a highly α-stereoselective glycosylation

Toshima, K., Mukaiyama, S., Ishiyama, T. & Tatsuta, K., 1990, In: Tetrahedron Letters. 31, 44, p. 6361-6362 2 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

The use of 2,6-anhydro-2-thio sugar for a highly stereocontrolled glycosylation: A novel strategy for synthesis of 2,6-dideoxy-α-glycosides

Toshima, K., Mukaiyama, S., Ishiyama, T. & Tatsuta, K., 1990, In: Tetrahedron Letters. 31, 23, p. 3339-3342 4 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

1989

A New Class of DNA‐Cleaving Molecules: pH‐Dependent DNA Cleavage by Propargylic and Allenic Sulfones

Nicolaou, K. C., Skokotas, G., Maligres, P., Zuccarello, G., Schweiger, E. J., Toshima, K. & Wendeborn, S., 1989 9月, In: Angewandte Chemie International Edition in English. 28, 9, p. 1272-1275 4 p.

研究成果: Article › 査読

98 被引用数 (Scopus)

Enantiospecific synthesis of C₂₀C₂₈ segment of concanamycin A: Application of diethylisopropylsilyl protecting group

Toshima, K., Misawa, M., Ohta, K., Tatsuta, K. & Kinoshita, M., 1989, In: Tetrahedron Letters. 30, 46, p. 6417-6420 4 p.

研究成果: Article › 査読

39 被引用数 (Scopus)

The diethylisopropylsilyl group: A new protecting group for alcohols

Toshima, K., Mukaiyama, S., Kinoshita, M. & Tatsuta, K., 1989, In: Tetrahedron Letters. 30, 46, p. 6413-6416 4 p.

研究成果: Article › 査読

38 被引用数 (Scopus)

1988

Total synthesis of elaiophylin (azalomycin B)

Toshima, K., Tatsuta, K. & Kinoshita, M., 1988 1月 1, In: Bulletin of the Chemical Society of Japan. 61, 7, p. 2369-2381 13 p.

研究成果: Article › 査読

Open Access

64 被引用数 (Scopus)

1986

Total synthesis of elaiophylin (azalomycin B)

Toshima, K., Tatsuta, K. & Kinoshita, M., 1986, In: Tetrahedron Letters. 27, 39, p. 4741-4744 4 p.

研究成果: Article › 査読

43 被引用数 (Scopus)

戸嶋 一敦

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戸嶋一敦