• 33352 引用
  • 87 h指数
1984 …2020
Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1984 2020

2020

A New Perspective on Dry Eye Classification: Proposal by the Asia Dry Eye Society

Members of The Asia Dry Eye Society, 2020 1 1, : : Eye & contact lens. 46, p. S2-S13

研究成果: Article

Tears
Mucins
Fluorescein
Wettability
Eye Diseases

A review on the epidemiology of myopia in school children worldwide

Grzybowski, A., Kanclerz, P., Tsubota, K., Lanca, C. & Saw, S. M., 2020 1 14, : : BMC ophthalmology. 20, 1, 1 p.

研究成果: Review article

公開
Myopia
Epidemiology
Mydriatics
Epidemiologic Studies
Mars

Estimation of the minimum effective dose of dietary supplement crocetin for prevention of myopia progression in mice

Mori, K., Kurihara, T., Jiang, X., Ikeda, S. I., Yotsukura, E., Torii, H. & Tsubota, K., 2020 1 1, : : Nutrients. 12, 1, 180.

研究成果: Article

公開
Myopia
Dietary Supplements
dietary supplements
animal models
mice
2019

Agaricus brasiliensis KA21 May Prevent Diet-Induced Nash through Its Antioxidant, Anti-Inflammatory, and Anti-Fibrotic Activities in the Liver

Nakamura, A., Zhu, Q., Yokoyama, Y., Kitamura, N., Uchida, S., Kumadaki, K., Tsubota, K. & Watanabe, M., 2019 1 1, : : Foods. 8, 11, 546.

研究成果: Article

公開
Agaricus subrufescens
Agaricus
Fatty Liver
alcoholism
Anti-Inflammatory Agents

Age-Related Conjunctival P2Y2 Receptor Alterations in the Cu, Zn-Superoxide Dismutase-1 (Sod1)-Knockout Dry Eye Model Mice

Dogru, M., Shinzawa, M., Kojima, T., Shimizu, T. & Tsubota, K., 2019 11 1, : : Eye & contact lens. 45, 6, p. 405-409 5 p.

研究成果: Article

Purinergic P2Y2 Receptors
Tears
Staining and Labeling
Fluorescein
Messenger RNA

Analysis of the association between the severity of ocular and systemic pain

Yamanishi, R., Uchino, M., Kawashima, M., Dogru, M., Matsuguma, S. & Tsubota, K., 2019 1 1, : : Ocular Surface.

研究成果: Article

Eye Pain
Eye Diseases
Pain Measurement
Visual Analog Scale
Quality of Life
2 引用 (Scopus)
公開
ischemia
hypoxia
inhibitors
Reperfusion
Screening
1 引用 (Scopus)
公開
Aquaporin 4
Synaptic Transmission
Fatigue
Retina
Knockout Mice
1 引用 (Scopus)

Association between retinal nerve fiber layer thickness and eye fatigue

Ayaki, M., Kuze, M., Kondo, M., Tsubota, K. & Negishi, K., 2019 1 1, : : BioMed Research International. 2019, 3014567.

研究成果: Article

公開
Asthenopia
Nerve Fibers
Fatigue of materials
Fibers
Ganglia
3 引用 (Scopus)

Changes in Murine Subbasal Corneal Nerves After Scopolamine-Induced Dry Eye Stress Exposure

Simsek, C., Kojima, T., Nagata, T., Dogru, M. & Tsubota, K., 2019 2 1, : : Investigative ophthalmology & visual science. 60, 2, p. 615-623 9 p.

研究成果: Article

公開
Scopolamine Hydrobromide
Tears
Dendritic Cells
Staining and Labeling
Fluorescein
1 引用 (Scopus)

Characteristics and Risk Factors Associated with Diagnosed and Undiagnosed Symptomatic Dry Eye Using a Smartphone Application

Inomata, T., Iwagami, M., Nakamura, M., Shiang, T., Yoshimura, Y., Fujimoto, K., Okumura, Y., Eguchi, A., Iwata, N., Miura, M., Hori, S., Hiratsuka, Y., Uchino, M., Tsubota, K., Dana, R. & Murakami, A., 2019 1 1, (Accepted/In press) : : JAMA Ophthalmology.

研究成果: Article

Odds Ratio
Eye Diseases
Depression
Seasonal Allergic Rhinitis
Contact Lenses
2 引用 (Scopus)

Choosing Core Outcomes for Use in Clinical Trials in Ophthalmology: Perspectives from Three Ophthalmology Outcomes Working Groups

Ophthalmology Outcomes Working Groups, 2019 1 1, : : Ophthalmology. 126, 1, p. 6-9 4 p.

研究成果: Editorial

公開
Ophthalmology
Clinical Trials
1 引用 (Scopus)

Clinical and Genetic Characteristics of East Asian Patients with Occult Macular Dystrophy (Miyake Disease): East Asia Occult Macular Dystrophy Studies Report Number 1

Fujinami, K., Yang, L., Joo, K., Tsunoda, K., Kameya, S., Hanazono, G., Fujinami-Yokokawa, Y., Arno, G., Kondo, M., Nakamura, N., Kurihara, T., Tsubota, K., Zou, X., Li, H., Park, K. H., Iwata, T., Miyake, Y., Woo, S. J. & Sui, R., 2019 1 1, : : Ophthalmology.

研究成果: Article

Far East
Macular Degeneration
Visual Acuity
Republic of Korea
China
1 引用 (Scopus)

Cluster of differentiation 30 expression in lacrimal gland and conjunctival tissues in patients with Sjögren's syndrome: Case series

Ogawa, A., Ogawa, Y., Mukai, S., Shimizu, E., Kuwana, M., Kawakami, Y. & Tsubota, K., 2019 7 1, : : Medicine. 98, 29, p. e16390

研究成果: Article

公開
Lacrimal Apparatus
Conjunctiva
Graft vs Host Disease
Lymphoma
Interferons

Commensal microflora in human conjunctiva; characteristics of microflora in the patients with chronic ocular graft-versus-host disease

Shimizu, E., Ogawa, Y., Saijo, Y., Yamane, M., Uchino, M., Kamoi, M., Fukui, M., Yang, F., He, J., Mukai, S. & Tsubota, K., 2019 1 1, : : Ocular Surface.

研究成果: Article

Conjunctiva
Graft vs Host Disease
Hematopoietic Stem Cell Transplantation
Gram-Positive Rods
Propionibacterium acnes
Intraocular Lenses
History
Denmark
Cataract
Germany

Corneal higher-order aberrations in eyes with chronic ocular graft-versus-host disease

Shimizu, E., Aketa, N., Yazu, H., Uchino, M., Kamoi, M., Sato, Y., Tsubota, K. & Ogawa, Y., 2019 1 1, (Accepted/In press) : : Ocular Surface.

研究成果: Article

Graft vs Host Disease
Hematopoietic Stem Cell Transplantation
Visual Acuity
Vision Disorders
Optical Coherence Tomography
2 引用 (Scopus)

Corneal Higher-Order Aberrations in Eyes with Corneal Scar after Traumatic Perforation

Shimizu, E., Yamaguchi, T., Tsubota, K. & Shimazaki, J., 2019 3 1, : : Eye and Contact Lens. 45, 2, p. 124-131 8 p.

研究成果: Article

Corneal Perforation
Cornea
Visual Acuity
Corneal Opacity
Tokyo
1 引用 (Scopus)

Corneal higher-order aberrations in Stevens-Johnson syndrome and toxic epidermal necrolysis

Ibrahim, O. M. A., Yagi-Yaguchi, Y., Noma, H., Tsubota, K., Shimazaki, J. & Yamaguchi, T., 2019 1 1, : : Ocular Surface.

研究成果: Article

Stevens-Johnson Syndrome
Pathologic Dilatations
Optical Coherence Tomography
Cornea
Visual Acuity

Corneal Sensory Experience via Transient Receptor Potential Vanilloid 1 Accelerates the Maturation of Neonatal Tearing

Jin, K., Imada, T., Nakamura, S., Izuta, Y., Oonishi, E., Shibuya, M., Sakaguchi, H., Tanabe, H., Ito, M., Katanosaka, K. & Tsubota, K., 2019 9 1, : : American Journal of Pathology. 189, 9, p. 1699-1710 12 p.

研究成果: Article

Tears
Parturition
Transient Receptor Potential Channels
Lacrimal Apparatus
vanilloid receptor subtype 1
1 引用 (Scopus)

Current Prevalence of Myopia and Association of Myopia with Environmental Factors among Schoolchildren in Japan

Yotsukura, E., Torii, H., Inokuchi, M., Tokumura, M., Uchino, M., Nakamura, K., Hyodo, M., Mori, K., Jiang, X., Ikeda, S. I., Kondo, S., Negishi, K., Kurihara, T. & Tsubota, K., 2019 1 1, (Accepted/In press) : : JAMA Ophthalmology.

研究成果: Article

Myopia
Japan
Students
Eye Diseases
Refractive Errors
2 引用 (Scopus)

Cytokine Levels in the Aqueous Humor Are Associated With Corneal Thickness in Eyes With Bullous Keratopathy

Suzuki, N., Yamaguchi, T., Shibata, S., Nagai, T., Noma, H., Tsubota, K. & Shimazaki, J., 2019 2 1, : : American Journal of Ophthalmology. 198, p. 174-180 7 p.

研究成果: Article

Aqueous Humor
Intercellular Adhesion Molecule-1
Cytokines
Interferons
P-Selectin
公開
Spirulina
Dietary Supplements
Proteins
Oxygen
Reactive Oxygen Species

Diurnal variation of human tear meniscus volume measured with tear strip meniscometry self-examination

Ayaki, M., Tachi, N., Hashimoto, Y., Kawashima, M., Tsubota, K. & Negishi, K., 2019 4 1, : : PloS one. 14, 4, e0215922.

研究成果: Article

公開
Self-Examination
diurnal variation
Tears
Optical tomography
Mirrors
公開
Vascular Endothelial Growth Factor A
Therapeutics
Injections
Choroid
Optical Coherence Tomography
公開
Retinal Perforations
Retinoschisis
Neurodegenerative Diseases
Optical Coherence Tomography
Retina
公開
Epiretinal Membrane
Temazepam
Vitrectomy
Visual Acuity
Confidence Intervals
1 引用 (Scopus)

Effect of eyelid hygiene detergent on obstructive meibomian gland dysfunction

Tanabe, H., Kaido, M., Kawashima, M., Ishida, R., Ayaki, M. & Tsubota, K., 2019 1 1, : : Journal of Oleo Science. 68, 1, p. 67-78 12 p.

研究成果: Article

Detergents
Water
Fluorescein
Medetomidine
Butorphanol
Midazolam
Pentobarbital
Xylazine

Effects of hyperoxia on the refraction in murine neonatal and adult models

Mori, K., Kurihara, T., Jiang, X., Ikeda, S. I., Ishida, A., Torii, H. & Tsubota, K., 2019 12 1, : : International journal of molecular sciences. 20, 23, 6014.

研究成果: Article

公開
hyperoxia
Hyperoxia
Refraction
refraction
Oxygen
4 引用 (Scopus)

Efficacy of Plate Expression of Meibum on Tear Function and Ocular Surface Findings in Meibomian Gland Disease

Aketa, N., Shinzawa, M., Kawashima, M., Dogru, M., Okamoto, S., Tsubota, K. & Shimazaki, J., 2019 1 1, : : Eye & contact lens. 45, 1, p. 19-22 4 p.

研究成果: Article

Meibomian Glands
Tears
Therapeutics
Quality of Life
Staining and Labeling

Enriched environment alleviates stress-induced dry-eye through the BDNF axis

Sano, K., Kawashima, M., Imada, T., Suzuki, T., Nakamura, S., Mimura, M., Tanaka, K. & Tsubota, K., 2019 12 1, : : Scientific reports. 9, 1, 3422.

研究成果: Article

公開
Brain-Derived Neurotrophic Factor
Tears
Eye Diseases
Gene Knockdown Techniques
Mental Disorders
2 引用 (Scopus)

Evaluation of AAV-DJ vector for retinal gene therapy

Katada, Y., Kobayashi, K., Tsubota, K. & Kurihara, T., 2019 1 1, : : PeerJ. 2019, 1, e6317.

研究成果: Article

Dependovirus
Gene therapy
gene therapy
Viruses
retina

HIF inhibitor topotecan has a neuroprotective effect in a murine retinal ischemia-reperfusion model

Kunimi, H., Miwa, Y., Katada, Y., Tsubota, K. & Kurihara, T., 2019 1 1, : : PeerJ. 2019, 10, e7849.

研究成果: Article

公開
Topotecan
neuroprotective effect
Retinal Ganglion Cells
Neuroprotective Agents
ischemia

Hydrogen-producing milk to prevent reduction in tear stability in persons using visual display terminals

Kawashima, M., Tsuno, S., Matsumoto, M. & Tsubota, K., 2019 10, : : Ocular Surface. 17, 4, p. 714-721 8 p.

研究成果: Article

Tears
Hydrogen
Milk
Fluorescein
Placebos
1 引用 (Scopus)

Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells

Fujii, S., Yoshida, S., Inagaki, E., Hatou, S., Tsubota, K., Takahashi, M., Shimmura, S. & Sugita, S., 2019 1 1, : : Stem Cells and Development. 28, 1, p. 28-43 16 p.

研究成果: Article

Induced Pluripotent Stem Cells
Neural Crest
Immunosuppressive Agents
T-Lymphocytes
Wound Healing

Impact of Corneal Higher-Order Aberrations on Visual Acuity After Deep Anterior Lamellar Keratoplasty in Treating Keratoconus

Suzuki, N., Yamaguchi, T., Tomida, D., Tsubota, K. & Shimazaki, J., 2019 7 1, : : Eye & contact lens. 45, 4, p. 238-245 8 p.

研究成果: Article

Descemet Membrane
Keratoconus
Corneal Transplantation
Visual Acuity
Cornea

Inducement and Evaluation of a Murine Model of Experimental Myopia

Jiang, X., Kurihara, T., Ikeda, S. I., Kunimi, H., Mori, K., Torii, H. & Tsubota, K., 2019 1 22, : : Journal of visualized experiments : JoVE. 143

研究成果: Article

Myopia
Lenses
Theoretical Models
Eyeglasses
Refraction
公開
Visual Acuity
Aptitude
Tears
Healthy Volunteers
1 引用 (Scopus)

Lack of social support and social trust as potential risk factors for dry eye disease: JPHC-NEXT study

for the JPHC-NEXT Study Group, 2019 4 1, : : Ocular Surface. 17, 2, p. 278-284 7 p.

研究成果: Article

Eye Diseases
Social Support
Odds Ratio
Japan
Public Health

Latanoprost could exacerbate the progression of presbyopia

Ayaki, M., Tsuneyoshi, Y., Yuki, K., Tsubota, K. & Negishi, K., 2019 1 1, : : PLoS One. 14, 1, e0211631.

研究成果: Article

latanoprost
Presbyopia
glaucoma
Glaucoma
Synthetic Prostaglandins

Melon GliSODin® prevents diet-induced NASH onset by reducing fat synthesis and improving liver function

Nakamura, A., Kitamura, N., Yokoyama, Y., Uchida, S., Kumadaki, K., Tsubota, K. & Watanabe, M., 2019 8 1, : : Nutrients. 11, 8, 1779.

研究成果: Article

公開
Cucurbitaceae
liver function
Fatty Liver
melons
Fats
1 引用 (Scopus)
公開
Biometry
Refractometry
Optical Coherence Tomography
Anterior Chamber
Intraocular Lenses

Ocular-component-specific miRNA expression in a murine model of lens-induced myopia

Tanaka, Y., Kurihara, T., Hagiwara, Y., Ikeda, S. I., Mori, K., Jiang, X., Torii, H. & Tsubota, K., 2019 8 1, : : International journal of molecular sciences. 20, 15, 3629.

研究成果: Article

公開
myopia
Myopia
MicroRNAs
Lenses
lenses
8 引用 (Scopus)

Oral crocetin administration suppressed refractive shift and axial elongation in a murine model of lens-induced myopia

Mori, K., Kurihara, T., Miyauchi, M., Ishida, A., Jiang, X., Ikeda, S. I., Torii, H. & Tsubota, K., 2019 12 1, : : Scientific Reports. 9, 1, 295.

研究成果: Article

Myopia
Lenses
Oral Administration
Early Growth Response Protein 1
Refractive Errors

Pemafibrate prevents retinal pathological neovascularization by increasing FGF21 level in a murine oxygen-induced retinopathy model

Tomita, Y., Ozawa, N., Miwa, Y., Ishida, A., Ohta, M., Tsubota, K. & Kurihara, T., 2019 12 1, : : International journal of molecular sciences. 20, 23, 5878.

研究成果: Article

公開
Pathologic Neovascularization
Retinal Neovascularization
Fenofibrate
angiogenesis
PPAR alpha
7 引用 (Scopus)
Retinal Neovascularization
Vascular Endothelial Growth Factor A
Pharmacology
Oxygen
Topotecan
Eye Diseases
Exercise
Leisure Activities
Confidence Intervals
Life Style
公開
Retinal Vein Occlusion
Macular Edema
Vascular Endothelial Growth Factor A
Visual Acuity
Recurrence