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研究成果 2001 2018

  • 1168 引用
  • 16 h指数
  • 27 Article
2018
1 引用 (Scopus)
Bowen's Disease
Centrioles
Epidermis
Squamous Cell Carcinoma
Cells

Rituximab therapy for refractory autoimmune bullous diseases: A multicenter, open-label, single-arm, phase 1/2 study on 10 Japanese patients

Kurihara, Y., Yamagami, J., Funakoshi, T., Ishii, M., Miyamoto, J., Fujio, Y., Kakuta, R., Tanikawa, A., Aoyama, Y., Iwatsuki, K., Ishii, N., Hashimoto, T., Nishie, W., Shimizu, H., Koyama, K. & Amagai, M., 2018 1 1, (Accepted/In press) : : Journal of Dermatology.

研究成果: Article

Pemphigus
Autoimmune Diseases
Bullous Pemphigoid
Therapeutics
Infectious Arthritis
2016

Effects of laser in situ keratomileusis on mental health-related quality of life

Tounaka-Fujii, K., Yuki, K., Negishi, K., Toda, I., Abe, T., Koyama, K. & Tsubota, K., 2016 9 26, : : Clinical Ophthalmology. 10, p. 1859-1864 6 p.

研究成果: Article

Laser In Situ Keratomileusis
Mental Health
Quality of Life
Health Surveys
Linear Models
2015
6 引用 (Scopus)

Glaucomatous visual field defect severity and the prevalence of motor vehicle collisions in Japanese: A hospital/clinic-based cross-sectional study

Ono, T., Yuki, K., Asaoka, R., Koyama, K., Abe, T., Tanabe, S., Fukagawa, K., Uchino, M., Shimoyama, M., Ozawa, Y., Ozeki, N., Shiba, D. & Tsubota, K., 2015, : : Journal of Ophthalmology. 2015, 497067.

研究成果: Article

Motor Vehicles
Visual Fields
Cross-Sectional Studies
Logistic Models
Primary Open Angle Glaucoma
2014
56 引用 (Scopus)

Distinct behavior of human Langerhans cells and inflammatory dendritic epidermal cells at tight junctions in patients with atopic dermatitis

Yoshida, K., Kubo, A., Fujita, H., Yokouchi, M., Ishii, K., Kawasaki, H., Nomura, T., Shimizu, H., Koyama, K., Ebihara, T., Nagao, K. & Amagai, M., 2014 10 1, : : Journal of Allergy and Clinical Immunology. 134, 4, p. 856-864 9 p.

研究成果: Article

Langerhans Cells
Tight Junctions
Atopic Dermatitis
Skin
Dendrites
3 引用 (Scopus)
Eye Diseases
Deterioration
Mental Health
Health
Quality of Life
15 引用 (Scopus)

Risk factors for decreased bone mineral density in inflammatory bowel disease: A cross-sectional study

Wada, Y., Hisamatsu, T., Naganuma, M., Matsuoka, K., Okamoto, S., Inoue, N., Yajima, T., Koyama, K., Iwao, Y., Ogata, H., Hibi, T., Abe, T. & Kanai, T., 2014 6 4, (Accepted/In press) : : Clinical Nutrition.

研究成果: Article

Inflammatory Bowel Diseases
Bone Density
Cross-Sectional Studies
Metabolic Bone Diseases
Ulcerative Colitis
2013
2 引用 (Scopus)
Trabeculectomy
Anterior Chamber
Intraocular Pressure
Incidence
Mitomycin
17 引用 (Scopus)
Frozen Sections
Endometrial Neoplasms
Magnetic Resonance Imaging
Sensitivity and Specificity
Retrospective Studies
19 引用 (Scopus)

The association between visual field defect severity and fear of falling in primary open-angle glaucoma

Yuki, K., Tanabe, S., Koyama, K., Fukagawa, K., Uchino, M., Shimoyama, M., Ozeki, N., Shiba, D., Ozawa, Y., Abe, T. & Tsubota, K., 2013 11 21, : : Investigative Ophthalmology and Visual Science. 54, 12, p. 7739-7745 7 p.

研究成果: Article

Accidental Falls
Visual Fields
Fear
Confidence Intervals
Logistic Models
2012
24 引用 (Scopus)

Indocyanine green fluorescence imaging for evaluation of uterine blood flow in cynomolgus macaque

Kisu, I., Banno, K., Mihara, M., Lin, L. Y., Tsuji, K., Yanokura, M., Hara, H., Araki, J., Iida, T., Abe, T., Koyama, K., Suganuma, N. & Aoki, D., 2012 4 20, : : PLoS One. 7, 4, e35124.

研究成果: Article

Indocyanine Green
Macaca fascicularis
Optical Imaging
Hemodynamics
Macaca
2011
8 引用 (Scopus)

Flexible hysteroscopy with narrow band imaging (NBI) for endoscopic diagnosis of malignant endometrial lesions

Kisu, I., Banno, K., Kobayashi, Y., Ono, A., Masuda, K., Ueki, A., Nomura, H., Hirasawa, A., Abe, T., Kouyama, K., Susumu, N. & Aoki, D., 2011 3, : : International Journal of Oncology. 38, 3, p. 613-618 6 p.

研究成果: Article

Narrow Band Imaging
Hysteroscopy
Confidence Intervals
Endometrial Hyperplasia
Endometrial Neoplasms
5 引用 (Scopus)

Narrow band imaging hysteroscopy: A comparative study using randomized video images

Kisu, I., Banno, K., Kobayashi, Y., Ono, A., Masuda, K., Ueki, A., Nomura, H., Hirasawa, A., Abe, T., Kouyama, K., Susumu, N. & Aoki, D., 2011 11, : : International Journal of Oncology. 39, 5, p. 1057-1062 6 p.

研究成果: Article

Narrow Band Imaging
Hysteroscopy
Light
Endometrial Hyperplasia
Endometrial Neoplasms
37 引用 (Scopus)
Motor Vehicles
Primary Open Angle Glaucoma
Eye Diseases
Age Factors
Visual Fields
2010
5 引用 (Scopus)

Clinical research in Japan: Past, present and future

Sato, Y. & Koyama, K., 2010 9, : : Keio Journal of Medicine. 59, 3, p. 104-109 6 p.

研究成果: Article

Japan
Research
Drug Approval
Clinical Trials
Equipment and Supplies
2008
61 引用 (Scopus)

A Real-Time Three-Dimensional Echocardiographic Quantitative Analysis of Left Atrial Function in Left Ventricular Diastolic Dysfunction

Murata, M., Iwanaga, S., Tamura, Y., Kondo, M., Koyama, K., Murata, M. & Ogawa, S., 2008 10 15, : : American Journal of Cardiology. 102, 8, p. 1097-1102 6 p.

研究成果: Article

Left Atrial Function
Left Ventricular Dysfunction
Left Ventricular Function
Echocardiography
Stroke Volume
2005
75 引用 (Scopus)

A humanin derivative, S14G-HN, prevents amyloid-β-induced memory impairment in mice

Tajima, H., Kawasumi, M., Chiba, T., Yamada, M., Yamashita, K., Nawa, M., Kita, Y., Koyama, K., Aiso, S., Matsuoka, M., Niikura, T. & Nishimoto, I., 2005 3 1, : : Journal of Neuroscience Research. 79, 5, p. 714-723 10 p.

研究成果: Article

Amyloid
Amnesia
Alzheimer Disease
Protein-Tyrosine Kinases
Cholinergic Neurons
2004
53 引用 (Scopus)

Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-β peptides via p75NTR/PLAIDD

Hashimoto, Y., Kaneko, Y., Tsukamoto, E., Frankowski, H., Koyama, K., Kita, Y., Niikura, T., Aiso, S., Bredesen, D. E., Matsuoka, M. & Nishimoto, I., 2004 8, : : Journal of Neurochemistry. 90, 3, p. 549-558 10 p.

研究成果: Article

Nerve Growth Factor Receptor
Cell death
Amyloid
Cell Death
Apoptosis
37 引用 (Scopus)

Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice

Kawasumi, M., Chiba, T., Yamada, M., Miyamae-Kaneko, M., Matsuoka, M., Nakahara, J., Tomita, T., Iwatsubo, T., Kato, S., Aiso, S., Nishimoto, I. & Koyama, K., 2004 5, : : European Journal of Neuroscience. 19, 10, p. 2826-2838 13 p.

研究成果: Article

Amyloid beta-Protein Precursor
Alzheimer Disease
Mutation
Genes
Short-Term Memory
2003
22 引用 (Scopus)

Analysis of neurons created from wild-type and Alzheimer's mutation knock-in embryonic stem cells by a highly efficient differentiation protocol

Abe, Y., Koyama, K., Tomita, T., Tomita, Y., Ban, N., Nawa, M., Matsuoka, M., Niikura, T., Aiso, S., Kita, Y., Iwatsubo, T. & Nishimoto, I., 2003 9 17, : : Journal of Neuroscience. 23, 24, p. 8513-8525 13 p.

研究成果: Article

Embryonic Stem Cells
Neurons
Mutation
Alzheimer Disease
Amyloid beta-Protein Precursor
80 引用 (Scopus)

Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death

Hashimoto, Y., Tsuji, O., Niikura, T., Yamagishi, Y., Ishizaka, M., Kawasumi, M., Chiba, T., Kanekura, K., Yamada, M., Tsukamoto, E., Koyama, K., Terashita, K., Aiso, S., Lint, A. & Nishimoto, I., 2003 2, : : Journal of Neurochemistry. 84, 4, p. 864-877 14 p.

研究成果: Article

JNK Mitogen-Activated Protein Kinases
Amyloid beta-Protein Precursor
Cell death
Cell Death
Pertussis Toxin
2002
33 引用 (Scopus)

p53-independent apoptosis is induced by the p19ARF tumor suppressor

Tsuji, K., Mizumoto, K., Sudo, H., Koyama, K., Ogata, E. & Matsuoka, M., 2002, : : Biochemical and Biophysical Research Communications. 295, 3, p. 621-629 9 p.

研究成果: Article

Tumors
Apoptosis
Cells
Neoplasms
Fibroblasts
2001
357 引用 (Scopus)

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

Hashimoto, Y., Niikura, T., Tajima, H., Yasukawa, T., Sudo, H., Ito, Y., Kita, Y., Kawasumi, M., Koyama, K., Doyu, M., Sobue, G., Koide, T., Tsuji, S., Lang, J., Kurokawa, K. & Nishimoto, I., 2001 5 22, : : Proceedings of the National Academy of Sciences of the United States of America. 98, 11, p. 6336-6341 6 p.

研究成果: Article

Alzheimer Disease
Cell Death
Peptides
Complementary DNA
Genes
158 引用 (Scopus)

c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK

Matsuda, S., Yasukawa, T., Homma, Y., Ito, Y., Niikura, T., Hiraki, T., Hirai, S., Ohno, S., Kita, Y., Kawasumi, M., Koyama, K., Yamamoto, T., Kyriakis, J. M. & Nishimoto, I., 2001 9 1, : : Journal of Neuroscience. 21, 17, p. 6597-6607 11 p.

研究成果: Article

JNK Mitogen-Activated Protein Kinases
Amyloid beta-Protein Precursor
Brain
Phosphotyrosine
Proteins
62 引用 (Scopus)

Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer's V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner

Niikura, T., Hashimoto, Y., Okamoto, T., Abe, Y., Yasukawa, T., Kawasumi, M., Hiraki, T., Kita, Y., Terashita, K., Koyama, K. & Nishimoto, I., 2001 3 15, : : Journal of Neuroscience. 21, 6, p. 1902-1910 9 p.

研究成果: Article

Insulin-Like Growth Factor Binding Proteins
IGF Type 1 Receptor
Mutant Proteins
Insulin-Like Growth Factor I
Amyloid
29 引用 (Scopus)

Secreted Aβ does not mediate neurotoxicity by antibody-stimulated amyloid precursor protein

Sudo, H., Hashimoto, Y., Niikura, T., Shao, Z., Yasukawa, T., Ito, Y., Yamada, M., Hata, M., Hiraki, T., Kawasumi, M., Koyama, K. & Nishimoto, I., 2001, : : Biochemical and Biophysical Research Communications. 282, 2, p. 548-556 9 p.

研究成果: Article

Amyloid beta-Protein Precursor
Anti-Idiotypic Antibodies
Antibodies
Toxicity
Cause of Death