• 18654 引用
  • 73 h指数
1985 …2020

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

フィルター
Article
2020

2-Nitroimidazoles induce mitochondrial stress and ferroptosis in glioma stem cells residing in a hypoxic niche

Koike, N., Kota, R., Naito, Y., Hayakawa, N., Matsuura, T., Hishiki, T., Onishi, N., Fukada, J., Suematsu, M., Shigematsu, N., Saya, H. & Sampetrean, O., 2020 12 1, : : Communications biology. 3, 1, 450.

研究成果: Article

公開

Annexin A1 accounts for an anti-inflammatory binding target of sesamin metabolites

Kabe, Y., Takemoto, D., Kanai, A., Hirai, M., Ono, Y., Akazawa, S., Horikawa, M., Kitagawa, Y., Handa, H., Rogi, T., Shibata, H. & Suematsu, M., 2020 12 1, : : npj Science of Food. 4, 1, 4.

研究成果: Article

公開

Comparative Glycomic Analysis of Exosome Subpopulations Derived from Pancreatic Cancer Cell Lines

Matsuda, A., Kuno, A., Yoshida, M., Wagatsuma, T., Sato, T., Miyagishi, M., Zhao, J., Suematsu, M., Kabe, Y. & Narimatsu, H., 2020 6 5, : : Journal of Proteome Research. 19, 6, p. 2516-2524 9 p.

研究成果: Article

1 引用 (Scopus)

Comparison of a Novel Bisphosphonate Prodrug and Zoledronic Acid in the Induction of Cytotoxicity in Human Vγ2Vδ2 T Cells

Okuno, D., Sugiura, Y., Sakamoto, N., Tagod, M. S. O., Iwasaki, M., Noda, S., Tamura, A., Senju, H., Umeyama, Y., Yamaguchi, H., Suematsu, M., Morita, C. T., Tanaka, Y. & Mukae, H., 2020 7 21, : : Frontiers in Immunology. 11, 1405.

研究成果: Article

公開

C-type lectin Mincle mediates cell death-triggered inflammation in acute kidney injury

Tanaka, M., Saka-Tanaka, M., Ochi, K., Fujieda, K., Sugiura, Y., Miyamoto, T., Kohda, H., Ito, A., Miyazawa, T., Matsumoto, A., Aoe, S., Miyamoto, Y., Tsuboi, N., Maruyama, S., Suematsu, M., Yamasaki, S., Ogawa, Y. & Suganami, T., 2020 11 2, : : The Journal of experimental medicine. 217, 11

研究成果: Article

公開

Identification and local manipulation of bone marrow vasculature during intravital imaging

Morikawa, T., Tamaki, S., Fujita, S., Suematsu, M. & Takubo, K., 2020 12 1, : : Scientific reports. 10, 1, 6422.

研究成果: Article

公開

Loss of autophagy impairs physiological steatosis by accumulation of NCoR1

Takahashi, S. S., Sou, Y. S., Saito, T., Kuma, A., Yabe, T., Sugiura, Y., Lee, H. C., Suematsu, M., Yokomizo, T., Koike, M., Terai, S., Mizushima, N., Waguri, S. & Komatsu, M., 2020, : : Life Science Alliance. 3, 1, e201900513.

研究成果: Article

公開
1 引用 (Scopus)

Quantitative MALDI-MS/MS assay for serum cortisol through charged derivatization

Nakamura, M., Moritsuna, M., Yuda, K., Fujimura, S., Sugiura, Y., Shimma, S., Nishimoto, K., Nishikawa, T., Suematsu, M., Ogawa, S. & Higashi, T., 2020 1 30, : : Journal of Pharmaceutical and Biomedical Analysis. 178, 112912.

研究成果: Article

1 引用 (Scopus)

Starvation causes female-to-male sex reversal through lipid metabolism in the teleost fish, medaka (Olyzias latipes)

Sakae, Y., Oikawa, A., Sugiura, Y., Mita, M., Nakamura, S., Nishimura, T., Suematsu, M. & Tanaka, M., 2020 4, : : Biology Open. 9, 4, bio050054.

研究成果: Article

公開
1 引用 (Scopus)

Vitamin B1 Supports the Differentiation of T Cells through TGF-β Superfamily Production in Thymic Stromal Cells

Hirata, S. I., Sawane, K., Adachi, J., Isoyama, J., Sugiura, Y., Matsunaga, A., Hosomi, K., Tomonaga, T., Suematsu, M., Nagatake, T. & Kunisawa, J., 2020 9 25, : : iScience. 23, 9, 101426.

研究成果: Article

公開
2019

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

Tanoue, T., Morita, S., Plichta, D. R., Skelly, A. N., Suda, W., Sugiura, Y., Narushima, S., Vlamakis, H., Motoo, I., Sugita, K., Shiota, A., Takeshita, K., Yasuma-Mitobe, K., Riethmacher, D., Kaisho, T., Norman, J. M., Mucida, D., Suematsu, M., Yaguchi, T., Bucci, V. および8人, Inoue, T., Kawakami, Y., Olle, B., Roberts, B., Hattori, M., Xavier, R. J., Atarashi, K. & Honda, K., 2019 1 31, : : Nature. 565, 7741, p. 600-605 6 p.

研究成果: Article

150 引用 (Scopus)

A thin layer of sucrose octasulfate protects the oesophageal mucosal epithelium in reflux oesophagitis

Hayakawa, T., Kawasaki, S., Hirayama, Y., Tsutsui, T., Sugiyama, E., Adachi, K., Kon, R., Suematsu, M. & Sugiura, Y., 2019 12 1, : : Scientific reports. 9, 1, 3559.

研究成果: Article

公開

Autophagy regulates lipid metabolism through selective turnover of NCoR1

Saito, T., Kuma, A., Sugiura, Y., Ichimura, Y., Obata, M., Kitamura, H., Okuda, S., Lee, H. C., Ikeda, K., Kanegae, Y., Saito, I., Auwerx, J., Motohashi, H., Suematsu, M., Soga, T., Yokomizo, T., Waguri, S., Mizushima, N. & Komatsu, M., 2019 12 1, : : Nature communications. 10, 1, 1567.

研究成果: Article

公開
34 引用 (Scopus)

Cancer Stem-Cell Marker CD44v9-Positive Cells Arise From Helicobacter pylori–Infected CAPZA1-Overexpressing Cells

Tsugawa, H., Kato, C., Mori, H., Matsuzaki, J., Kameyama, K., Saya, H., Hatakeyama, M., Suematsu, M. & Suzuki, H., 2019, : : CMGH. 8, 3, p. 319-334 16 p.

研究成果: Article

公開
3 引用 (Scopus)

CAPZA1 determines the risk of gastric carcinogenesis by inhibiting Helicobacter pylori CagA-degraded autophagy

Tsugawa, H., Mori, H., Matsuzaki, J., Sato, A., Saito, Y., Imoto, M., Suematsu, M. & Suzuki, H., 2019 2 1, : : Autophagy. 15, 2, p. 242-258 17 p.

研究成果: Article

5 引用 (Scopus)

Detection of a High-Turnover Serotonin Circuit in the Mouse Brain Using Mass Spectrometry Imaging

Sugiyama, E., Guerrini, M. M., Honda, K., Hattori, Y., Abe, M., Källback, P., Andrén, P. E., Tanaka, K. F., Setou, M., Fagarasan, S., Suematsu, M. & Sugiura, Y., 2019 10 25, : : iScience. 20, p. 359-372 14 p.

研究成果: Article

公開
3 引用 (Scopus)

Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo

Kobayashi, H., Morikawa, T., Okinaga, A., Hamano, F., Hashidate-Yoshida, T., Watanuki, S., Hishikawa, D., Shindou, H., Arai, F., Kabe, Y., Suematsu, M., Shimizu, T. & Takubo, K., 2019 7 2, : : Cell Reports. 28, 1, p. 145-158.e9

研究成果: Article

公開
8 引用 (Scopus)

Fatty acid β-oxidation-dependent and -independent responses and tumor aggressiveness acquired under mild hypoxia

Wakui, M., Kawai, K., Mizushima, T., Nishime, C., Serizawa, A., Suemizu, H., Asakura, K., Yamauchi, Y., Hayashida, T., Suematsu, M. & Murata, M., 2019 1, : : Anticancer research. 39, 1, p. 191-200 10 p.

研究成果: Article

Hydrogen sulfide bypasses the rate-limiting oxygen activation of heme oxygenase

Matsui, T., Sugiyama, R., Sakanashi, K., Tamura, Y., Iida, M., Nambu, Y., Higuchi, T., Suematsu, M. & Ikeda-Saito, M., 2019 10 26, : : Journal of Biological Chemistry. 293, 43, p. 16931-16939 9 p.

研究成果: Article

公開
2 引用 (Scopus)

Identification of a binding protein for sesamin and characterization of its roles in plant growth

Tera, M., Koyama, T., Murata, J., Furukawa, A., Mori, S., Azuma, T., Watanabe, T., Hori, K., Okazawa, A., Kabe, Y., Suematsu, M., Satake, H., Ono, E. & Horikawa, M., 2019 12 1, : : Scientific reports. 9, 1, 8631.

研究成果: Article

公開
4 引用 (Scopus)

IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma

Kofuji, S., Hirayama, A., Eberhardt, A. O., Kawaguchi, R., Sugiura, Y., Sampetrean, O., Ikeda, Y., Warren, M., Sakamoto, N., Kitahara, S., Yoshino, H., Yamashita, D., Sumita, K., Wolfe, K., Lange, L., Ikeda, S., Shimada, H., Minami, N., Malhotra, A., Morioka, S. および37人, Ban, Y., Asano, M., Flanary, V. L., Ramkissoon, A., Chow, L. M. L., Kiyokawa, J., Mashimo, T., Lucey, G., Mareninov, S., Ozawa, T., Onishi, N., Okumura, K., Terakawa, J., Daikoku, T., Wise-Draper, T., Majd, N., Kofuji, K., Sasaki, M., Mori, M., Kanemura, Y., Smith, E. P., Anastasiou, D., Wakimoto, H., Holland, E. C., Yong, W. H., Horbinski, C., Nakano, I., DeBerardinis, R. J., Bachoo, R. M., Mischel, P. S., Yasui, W., Suematsu, M., Saya, H., Soga, T., Grummt, I., Bierhoff, H. & Sasaki, A. T., 2019 8 1, : : Nature Cell Biology. 21, 8, p. 1003-1014 12 p.

研究成果: Article

14 引用 (Scopus)

Increased cytotoxicity of herpes simplex virus thymidine kinase expression in human induced pluripotent stem cells

Iwasawa, C., Tamura, R., Sugiura, Y., Suzuki, S., Kuzumaki, N., Narita, M., Suematsu, M., Nakamura, M., Yoshida, K., Toda, M., Okano, H. & Miyoshi, H., 2019 2 2, : : International journal of molecular sciences. 20, 4, 810.

研究成果: Article

公開
6 引用 (Scopus)

Mechanical allodynia induced by optogenetic sensory nerve excitation activates dopamine signaling and metabolism in medial nucleus accumbens

Sugiyama, E., Kondo, T., Kuzumaki, N., Honda, K., Yamanaka, A., Narita, M., Suematsu, M. & Sugiura, Y., 2019 10, : : Neurochemistry International. 129, 104494.

研究成果: Article

公開
3 引用 (Scopus)

Small molecules assisting eggshell calcium dissolution for embryonic bone formation

Ito, T., Kato, S., Kubo, A., Suematsu, M., Nakata, M. & Saikawa, Y., 2019 1 1, (Accepted/In press) : : Tetrahedron. 130854.

研究成果: Article

1 引用 (Scopus)

Tandem Mass Spectrometry Imaging Reveals Distinct Accumulation Patterns of Steroid Structural Isomers in Human Adrenal Glands

Takeo, E., Sugiura, Y., Uemura, T., Nishimoto, K., Yasuda, M., Sugiyama, E., Ohtsuki, S., Higashi, T., Nishikawa, T., Suematsu, M., Fukusaki, E. & Shimma, S., 2019 7 16, : : Analytical chemistry. 91, 14, p. 8918-8925 8 p.

研究成果: Article

5 引用 (Scopus)

Xanthine oxidase inhibitor ameliorates postischemic renal injury in mice by promoting resynthesis of adenine nucleotides

Fujii, K., Kubo, A., Miyashita, K., Sato, M., Hagiwara, A., Inoue, H., Ryuzaki, M., Tamaki, M., Hishiki, T., Hayakawa, N., Kabe, Y., Itoh, H. & Suematsu, M., 2019 11 14, : : JCI Insight. 4, 22, e124816.

研究成果: Article

公開
1 引用 (Scopus)
2018

Aldosterone and 18-oxocortisol coaccumulation in aldosterone-producing lesions

Sugiura, Y., Takeo, E., Shimma, S., Yokota, M., Higashi, T., Seki, T., Mizuno, Y., Oya, M., Kosaka, T., Omura, M., Nishikawa, T., Suematsu, M. & Nishimoto, K., 2018 12, : : Hypertension. 72, 6, p. 1345-1354 10 p.

研究成果: Article

13 引用 (Scopus)
5 引用 (Scopus)
2 引用 (Scopus)

Brief exposure of skin to near-infrared laser modulates mast cell function and augments the immune response

Kimizuka, Y., Katagiri, W., Locascio, J. J., Shigeta, A., Sasaki, Y., Shibata, M., Morse, K., Sirbulescu, R. F., Miyatake, M., Reeves, P., Suematsu, M., Gelfand, J., Brauns, T., Poznansky, M. C., Tsukada, K. & Kashiwagi, S., 2018 12 15, : : Journal of Immunology. 201, 12, p. 3587-3603 17 p.

研究成果: Article

4 引用 (Scopus)

Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target

Nurkanto, A., Jeelani, G., Yamamoto, T., Naito, Y., Hishiki, T., Mori, M., Suematsu, M., Shiomi, K., Hashimoto, T. & Nozaki, T., 2018 4, : : International Journal for Parasitology: Drugs and Drug Resistance. 8, 1, p. 125-136 12 p.

研究成果: Article

3 引用 (Scopus)

Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye

Sakurai, T., Uruno, T., Sugiura, Y., Tatsuguchi, T., Yamamura, K., Ushijima, M., Hattori, Y., Kukimoto-Niino, M., Mishima-Tsumagari, C., Watanabe, M., Suematsu, M. & Fuku, Y., 2018 7 31, : : Science Signaling. 11, 541, eaao4874.

研究成果: Article

10 引用 (Scopus)

Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese

Okada, Y., Momozawa, Y., Sakaue, S., Kanai, M., Ishigaki, K., Akiyama, M., Kishikawa, T., Arai, Y., Sasaki, T., Kosaki, K., Suematsu, M., Matsuda, K., Yamamoto, K., Kubo, M., Hirose, N. & Kamatani, Y., 2018 12 1, : : Nature communications. 9, 1, 1631.

研究成果: Article

35 引用 (Scopus)

Development of a highly sensitive device for counting the number of disease-specific exosomes in human sera

Kabe, Y., Suematsu, M., Sakamoto, S., Hirai, M., Koike, I., Hishiki, T., Matsuda, A., Hasegawa, Y., Tsujita, K., Ono, M., Minegishi, N., Hozawa, A., Murakami, Y., Kubo, M., Itonaga, M. & Handa, H., 2018 10, : : Clinical Chemistry. 64, 10, p. 1463-1473 11 p.

研究成果: Article

13 引用 (Scopus)

Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: Evidence from fatty acid-binding protein-4 and-5 knockout mice

Umbarawan, Y., Syamsunarno, M. R. A. A., Koitabashi, N., Yamaguchi, A., Hanaoka, H., Hishiki, T., Nagahata-Naito, Y., Obinata, H., Sano, M., Sunaga, H., Matsui, H., Tsushima, Y., Suematsu, M., Kurabayashi, M. & Iso, T., 2018 7 1, : : Cardiovascular Research. 114, 8, p. 1132-1144 13 p.

研究成果: Article

8 引用 (Scopus)

Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival

Shiota, M., Naya, M., Yamamoto, T., Hishiki, T., Tani, T., Takahashi, H., Kubo, A., Koike, D., Itoh, M., Ohmura, M., Kabe, Y., Sugiura, Y., Hiraoka, N., Morikawa, T., Takubo, K., Suina, K., Nagashima, H., Sampetrean, O., Nagano, O., Saya, H. および3人, Yamazoe, S., Watanabe, H. & Suematsu, M., 2018 12 1, : : Nature Communications. 9, 1, 1561.

研究成果: Article

27 引用 (Scopus)

Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure

Umbarawan, Y., Syamsunarno, M. R. A. A., Koitabashi, N., Obinata, H., Yamaguchi, A., Hanaoka, H., Hishiki, T., Hayakawa, N., Sano, M., Sunaga, H., Matsui, H., Tsushima, Y., Suematsu, M., Kurabayashi, M. & Iso, T., 2018 12 1, : : Scientific reports. 8, 1, 12035.

研究成果: Article

8 引用 (Scopus)
9 引用 (Scopus)

Optogenetic astrocyte activation evokes BOLD fMRI response with oxygen consumption without neuronal activity modulation

Takata, N., Sugiura, Y., Yoshida, K., Koizumi, M., Hiroshi, N., Honda, K., Yano, R., Komaki, Y., Matsui, K., Suematsu, M., Mimura, M., Okano, H. & Tanaka, K. F., 2018 9, : : Glia. 66, 9, p. 2013-2023 11 p.

研究成果: Article

19 引用 (Scopus)

PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth

Morita, M., Sato, T., Nomura, M., Sakamoto, Y., Inoue, Y., Tanaka, R., Ito, S., Kurosawa, K., Yamaguchi, K., Sugiura, Y., Takizaki, H., Yamashita, Y., Katakura, R., Sato, I., Kawai, M., Okada, Y., Watanabe, H., Kondoh, G., Matsumoto, S., Kishimoto, A. および12人, Obata, M., Matsumoto, M., Fukuhara, T., Motohashi, H., Suematsu, M., Komatsu, M., Nakayama, K. I., Watanabe, T., Soga, T., Shima, H., Maemondo, M. & Tanuma, N., 2018 3 12, : : Cancer Cell. 33, 3, p. 355-367.e7

研究成果: Article

35 引用 (Scopus)

Plant hormone cytokinins control cell cycle progression and plastid replication in apicomplexan parasites

Andrabi, S. B. A., Tahara, M., Matsubara, R., Toyama, T., Aonuma, H., Sakakibara, H., Suematsu, M., Tanabe, K., Nozaki, T. & Nagamune, K., 2018 2, : : Parasitology International. 67, 1, p. 47-58 12 p.

研究成果: Article

公開
9 引用 (Scopus)
2 引用 (Scopus)

Sodium–glucose cotransporter 2 inhibition normalizes glucose metabolism and suppresses oxidative stress in the kidneys of diabetic mice

Tanaka, S., Sugiura, Y., Saito, H., Sugahara, M., Higashijima, Y., Yamaguchi, J., Inagi, R., Suematsu, M., Nangaku, M. & Tanaka, T., 2018 11, : : Kidney international. 94, 5, p. 912-925 14 p.

研究成果: Article

34 引用 (Scopus)
公開
2 引用 (Scopus)
2017

Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos

Oka, M., Hashimoto, K., Yamaguchi, Y., Saitoh, S. I., Sugiura, Y., Motoi, Y., Honda, K., Kikko, Y., Ohata, S., Suematsu, M., Miura, M., Miyake, K., Katada, T. & Kontani, K., 2017 1 1, : : Journal of Cell Science. 130, 20, p. 3568-3577 10 p.

研究成果: Article

9 引用 (Scopus)

Disorganized Steroidogenesis in Adrenocortical Carcinoma, a Case Study

Uchida, T., Nishimoto, K., Fukumura, Y., Asahina, M., Goto, H., Kawano, Y., Shimizu, F., Tsujimura, A., Seki, T., Mukai, K., Kabe, Y., Suematsu, M., Gomez-Sanchez, C. E., Yao, T., Horie, S. & Watada, H., 2017 3 1, : : Endocrine pathology. 28, 1, p. 27-35 9 p.

研究成果: Article

4 引用 (Scopus)

Japan's initiative on rare and undiagnosed diseases (IRUD): Towards an end to the diagnostic odyssey

Adachi, T., Kawamura, K., Furusawa, Y., Nishizaki, Y., Imanishi, N., Umehara, S., Izumi, K. & Suematsu, M., 2017 9 1, : : European Journal of Human Genetics. 25, 9, p. 1025-1028 4 p.

研究成果: Article

公開
25 引用 (Scopus)

Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior

Miyajima, M., Zhang, B., Sugiura, Y., Sonomura, K., Guerrini, M. M., Tsutsui, Y., Maruya, M., Vogelzang, A., Chamoto, K., Honda, K., Hikida, T., Ito, S., Qin, H., Sanuki, R., Suzuki, K., Furukawa, T., Ishihama, Y., Matsuda, F., Suematsu, M., Honjo, T. および1人, Fagarasan, S., 2017 11 16, : : Nature Immunology. 18, 12, p. 1342-1352 11 p.

研究成果: Article

41 引用 (Scopus)

Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling

Tai-Nagara, I., Yoshikawa, Y., Numata, N., Ando, T., Okabe, K., Sugiura, Y., Ieda, M., Takakura, N., Nakagawa, O., Zhou, B., Okabayashi, K., Suematsu, M., Kitagawa, Y., Bastmeyer, M., Sato, K., Klein, R., Navankasattusas, S., Li, D. Y., Yamagishi, S. & Kubota, Y., 2017, : : Development (Cambridge). 144, 13, p. 2392-2401 10 p.

研究成果: Article

8 引用 (Scopus)
1 引用 (Scopus)