• 519 引用
  • 14 h指数
20042020

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 519 引用
  • 14 h指数
  • 34 Article
  • 2 Review article
  • 1 Conference contribution
  • 1 Comment/debate
フィルター
Article
2020

2-Nitroimidazoles induce mitochondrial stress and ferroptosis in glioma stem cells residing in a hypoxic niche

Koike, N., Kota, R., Naito, Y., Hayakawa, N., Matsuura, T., Hishiki, T., Onishi, N., Fukada, J., Suematsu, M., Shigematsu, N., Saya, H. & Sampetrean, O., 2020 12 1, : : Communications biology. 3, 1, 450.

研究成果: Article

公開

A potent blood–brain barrier-permeable mutant IDH1 inhibitor suppresses the growth of glioblastoma with IDH1 mutation in a patient-derived orthotopic xenograft model

Machida, Y., Nakagawa, M., Matsunaga, H., Yamaguchi, M., Ogawara, Y., Shima, Y., Yamagata, K., Katsumoto, T., Hattori, A., Itoh, M., Seki, T., Nishiya, Y., Nakamura, K., Suzuki, K., Imaoka, T., Baba, D., Suzuki, M., Sampetrean, O., Saya, H., Ichimura, K. および1人, Kitabayashi, I., 2020 2, : : Molecular cancer therapeutics. 19, 2, p. 375-383 9 p.

研究成果: Article

3 引用 (Scopus)
公開

In Vitro Blood-Brain Barrier Permeability and Cytotoxicity of an Atorvastatin-Loaded Nanoformulation against Glioblastoma in 2D and 3D Models

Lübtow, M. M., Oerter, S., Quader, S., Jeanclos, E., Jeanclos, E., Cubukova, A., Krafft, M., Haider, M. S., Schulte, C., Meier, L., Rist, M., Sampetrean, O., Kinoh, H., Gohla, A., Kataoka, K., Kataoka, K., Appelt-Menzel, A., Appelt-Menzel, A., Luxenhofer, R. & Luxenhofer, R., 2020 6 1, : : Molecular Pharmaceutics. 17, 6, p. 1835-1847 13 p.

研究成果: Article

1 引用 (Scopus)
2019

IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma

Kofuji, S., Hirayama, A., Eberhardt, A. O., Kawaguchi, R., Sugiura, Y., Sampetrean, O., Ikeda, Y., Warren, M., Sakamoto, N., Kitahara, S., Yoshino, H., Yamashita, D., Sumita, K., Wolfe, K., Lange, L., Ikeda, S., Shimada, H., Minami, N., Malhotra, A., Morioka, S. および37人, Ban, Y., Asano, M., Flanary, V. L., Ramkissoon, A., Chow, L. M. L., Kiyokawa, J., Mashimo, T., Lucey, G., Mareninov, S., Ozawa, T., Onishi, N., Okumura, K., Terakawa, J., Daikoku, T., Wise-Draper, T., Majd, N., Kofuji, K., Sasaki, M., Mori, M., Kanemura, Y., Smith, E. P., Anastasiou, D., Wakimoto, H., Holland, E. C., Yong, W. H., Horbinski, C., Nakano, I., DeBerardinis, R. J., Bachoo, R. M., Mischel, P. S., Yasui, W., Suematsu, M., Saya, H., Soga, T., Grummt, I., Bierhoff, H. & Sasaki, A. T., 2019 8 1, : : Nature Cell Biology. 21, 8, p. 1003-1014 12 p.

研究成果: Article

14 引用 (Scopus)

Visualization of spatiotemporal dynamics of human glioma stem cell invasion

Tamura, R., Miyoshi, H., Sampetrean, O., Shinozaki, M., Morimoto, Y., Iwasawa, C., Fukaya, R., Mine, Y., Masuda, H., Maruyama, T., Narita, M., Saya, H., Yoshida, K., Okano, H. & Toda, M., 2019 5 6, : : Molecular brain. 12, 1, 45.

研究成果: Article

公開
6 引用 (Scopus)
2018
4 引用 (Scopus)

Convection-enhanced delivery of sulfasalazine prolongs survival in a glioma stem cell brain tumor model

Haryu, S., Saito, R., Jia, W., Shoji, T., Mano, Y., Sato, A., Kanamori, M., Sonoda, Y., Sampetrean, O., Saya, H. & Tominaga, T., 2018 1 1, : : Journal of Neuro-Oncology. 136, 1, p. 23-31 9 p.

研究成果: Article

5 引用 (Scopus)

Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate–sensitive glutamate receptor signaling

Suina, K., Tsuchihashi, K., Yamasaki, J., Kamenori, S., Shintani, S., Hirata, Y., Okazaki, S., Sampetrean, O., Baba, E., Akashi, K., Mitsuishi, Y., Takahashi, F., Takahashi, K., Saya, H. & Nagano, O., 2018 12, : : Cancer science. 109, 12, p. 3874-3882 9 p.

研究成果: Article

3 引用 (Scopus)

Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival

Shiota, M., Naya, M., Yamamoto, T., Hishiki, T., Tani, T., Takahashi, H., Kubo, A., Koike, D., Itoh, M., Ohmura, M., Kabe, Y., Sugiura, Y., Hiraoka, N., Morikawa, T., Takubo, K., Suina, K., Nagashima, H., Sampetrean, O., Nagano, O., Saya, H. および3人, Yamazoe, S., Watanabe, H. & Suematsu, M., 2018 12 1, : : Nature Communications. 9, 1, 1561.

研究成果: Article

27 引用 (Scopus)

HER2 heterogeneity is associated with poor survival in HER2-positive breast cancer

Hosonaga, M., Arima, Y., Sampetrean, O., Komura, D., Koya, I., Sasaki, T., Sato, E., Okano, H., Kudoh, J., Ishikawa, S., Saya, H. & Ishikawa, T., 2018 8, : : International journal of molecular sciences. 19, 8, 2158.

研究成果: Article

5 引用 (Scopus)

Metabolic heterogeneity and plasticity of glioma stem cells in a mouse glioblastoma model

Shibao, S., Minami, N., Koike, N., Fukui, N., Yoshida, K., Saya, H. & Sampetrean, O., 2018 2 19, : : Neuro-Oncology. 20, 3, p. 343-354 12 p.

研究成果: Article

11 引用 (Scopus)
5 引用 (Scopus)
2017

Blocking COX-2 induces apoptosis and inhibits cell proliferation via the Akt/survivin- and Akt/ID3 pathway in low-grade-glioma

Sato, A., Mizobuchi, Y., Nakajima, K., Shono, K., Fujihara, T., Kageji, T., Kitazato, K., Matsuzaki, K., Mure, H., Kuwayama, K., Sumi, A., Saya, H., Sampetrean, O. & Nagahirao, S., 2017 4 1, : : Journal of Neuro-Oncology. 132, 2, p. 231-238 8 p.

研究成果: Article

10 引用 (Scopus)

Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality

Kitagawa, M., Liao, P. J., Lee, K. H., Wong, J., Shang, S. C., Minami, N., Sampetrean, O., Saya, H., Lingyun, D., Prabhu, N., Diam, G. K., Sobota, R., Larsson, A., Nordlund, P., McCormick, F., Ghosh, S., Epstein, D. M., Dymock, B. W. & Lee, S. H., 2017 12 1, : : Nature communications. 8, 1, 2200.

研究成果: Article

23 引用 (Scopus)
18 引用 (Scopus)

Functional analysis of the DEPDC1 oncoantigen in malignant glioma and brain tumor initiating cells

Kikuchi, R., Sampetrean, O., Saya, H., Yoshida, K. & Toda, M., 2017 5 29, (Accepted/In press) : : Journal of Neuro-Oncology. p. 1-11 11 p.

研究成果: Article

5 引用 (Scopus)

Organotypic brain explant culture as a drug evaluation system for malignant brain tumors

Minami, N., Maeda, Y., Shibao, S., Arima, Y., Ohka, F., Kondo, Y., Maruyama, K., Kusuhara, M., Sasayama, T., Kohmura, E., Saya, H. & Sampetrean, O., 2017 11, : : Cancer medicine. 6, 11, p. 2635-2645 11 p.

研究成果: Article

10 引用 (Scopus)
15 引用 (Scopus)
2016

Generation of heterozygous fibrillin-1 mutant cloned pigs from genome-edited foetal fibroblasts

Umeyama, K., Watanabe, K., Watanabe, M., Horiuchi, K., Nakano, K., Kitashiro, M., Matsunari, H., Kimura, T., Arima, Y., Sampetrean, O., Nagaya, M., Saito, M., Saya, H., Kosaki, K., Nagashima, H. & Matsumoto, M., 2016 4 14, : : Scientific reports. 6, 24413.

研究成果: Article

17 引用 (Scopus)

Histopathological investigation of glioblastomas resected under bevacizumab treatment

Tamura, R., Tanaka, T., Miyake, K., Tabei, Y., Ohara, K., Sampetrean, O., Kono, M., Mizutani, K., Yamamoto, Y., Murayama, Y., Tamiya, T., Yoshida, K. & Sasaki, H., 2016 8 1, : : Oncotarget. 7, 32, p. 52423-52435 13 p.

研究成果: Article

25 引用 (Scopus)

The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-)

Tsuchihashi, K., Okazaki, S., Ohmura, M., Ishikawa, M., Sampetrean, O., Onishi, N., Wakimoto, H., Yoshikawa, M., Seishima, R., Iwasaki, Y., Morikawa, T., Abe, S., Takao, A., Shimizu, M., Masuko, T., Nagane, M., Furnari, F. B., Akiyama, T., Suematsu, M., Baba, E. および3人, Akashi, K., Saya, H. & Nagano, O., 2016 5 15, : : Cancer Research. 76, 10, p. 2954-2963 10 p.

研究成果: Article

32 引用 (Scopus)
2015

Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression

Kozono, D., Li, J., Nitta, M., Sampetrean, O., Gonda, D., Kushwaha, D. S., Merzon, D., Ramakrishnan, V., Zhu, S., Zhu, K., Matsui, H., Harismendy, O., Hua, W., Mao, Y., Kwon, C. H., Saya, H., Nakano, I., Pizzo, D. P., Van Den Berg, S. R. & Chen, C. C., 2015 7 28, : : Proceedings of the National Academy of Sciences of the United States of America. 112, 30, p. E4055-E4064

研究成果: Article

31 引用 (Scopus)
2014

Basic biology of gliomas

Saya, H., Shibao, S. & Sampetrean, O., 2014 1 1, : : Japanese Journal of Neurosurgery. 23, 7, p. 541-546 6 p.

研究成果: Article

公開

Integrated analysis identifies different metabolic signatures for tumor-initiating cells in a murine glioblastoma model

Saga, I., Shibao, S., Okubo, J., Osuka, S., Kobayashi, Y., Yamada, S., Fujita, S., Urakami, K., Kusuhara, M., Yoshida, K., Saya, H. & Sampetrean, O., 2014 8, : : Neuro-oncology. 16, 8, p. 1048-1056 9 p.

研究成果: Article

26 引用 (Scopus)
2013

Characteristics of glioma stem cells

Sampetrean, O. & Saya, H., 2013 10, : : Brain tumor pathology. 30, 4, p. 209-214 6 p.

研究成果: Article

34 引用 (Scopus)

IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells

Osuka, S., Sampetrean, O., Shimizu, T., Saga, I., Onishi, N., Sugihara, E., Okubo, J., Fujita, S., Takano, S., Matsumura, A. & Saya, H., 2013 4, : : Stem Cells. 31, 4, p. 627-640 14 p.

研究成果: Article

70 引用 (Scopus)
2011

Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells

Sampetrean, O., Saga, I., Nakanishi, M., Sugihara, E., Fukaya, R., Onishi, N., Osuka, S., Akahata, M., Kai, K., Sugimoto, H., Hirao, A. & Saya, H., 2011 9, : : Neoplasia. 13, 9, p. 784-791 8 p.

研究成果: Article

54 引用 (Scopus)
2009

Maintenance of HCT116 colon cancer cell line conforms to a stochastic model but not a cancer stem cell model

Kai, K., Nagano, O., Sugihara, E., Arima, Y., Sampetrean, O., Ishimoto, T., Nakanishi, M., Ueno, N. T., Iwase, H. & Saya, H., 2009 12 1, : : Cancer science. 100, 12, p. 2275-2282 8 p.

研究成果: Article

35 引用 (Scopus)

Reversible whole-organism cell cycle arrest in a living vertebrate

Sampetrean, O., Lida, S. I., Makino, S., Matsuzaki, Y., Ohno, K. & Saya, H., 2009 2 15, : : Cell Cycle. 8, 4, p. 620-627 8 p.

研究成果: Article

公開
7 引用 (Scopus)
2008

Endosaccular embolization of an intrasellar aneurysm with hypopituitarism: Case report

Fujii, M., Tone, O., Tomita, H., Tamaki, M., Akimoto, H., Shigeta, K., Sampetrean, O., Kanno, K. & Matsushita, M., 2008 4 1, : : Neurological Surgery. 36, 4, p. 329-337 9 p.

研究成果: Article

3 引用 (Scopus)
2006

Coil embolization for ruptured cerebral aneurysms fo 2x3 mm diameter

Tone, O., Tomita, H., Tamaki, M., Akimoto, H., Shigeta, K., Sampetrean, O. & Fujii, M., 2006 1 1, : : Interventional Neuroradiology. 12, SUPPL. 1, p. 97-100 4 p.

研究成果: Article

Rapidly growing dysembryoplastic neuroepithelial tumor: Case report

Sampetrean, O., Maehara, T., Arai, N. & Nemoto, T., 2006 12 1, : : Neurosurgery. 59, 6, p. E1337-E1338

研究成果: Article

16 引用 (Scopus)
2004

Endovascular surgery as the first-choice treatment for ruptured cerebral aneurysms: How far has it come?

Tone, O., Tomita, H., Tamaki, M., Satoh, Y., Matsuoka, Y., Sampetrean, O., Nakabayaashi, M., Katsumi, A. & Suzaki, S., 2004 12, : : Interventional Neuroradiology. 10, SUPPL. 2, p. 41-47 7 p.

研究成果: Article

1 引用 (Scopus)