• 2808 引用
  • 31 h指数
1983 …2020

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 2808 引用
  • 31 h指数
  • 97 Article
  • 3 Review article
  • 1 Chapter
  • 1 Conference contribution
フィルター
Article
2020

Inhibitors of the protein–protein interaction between phosphorylated p62 and Keap1 attenuate chemoresistance in a human hepatocellular carcinoma cell line

Yasuda, D., Ohe, T., Takahashi, K., Imamura, R., Kojima, H., Okabe, T., Ichimura, Y., Komatsu, M., Yamamoto, M., Nagano, T. & Mashino, T., 2020 1 1, (Accepted/In press) : : Free Radical Research.

研究成果: Article

1 引用 (Scopus)

Synthesis and evaluation of nevirapine analogs to study the metabolic activation of nevirapine

Tateishi, Y., Ohe, T., Yasuda, D., Takahashi, K., Nakamura, S., Kazuki, Y. & Mashino, T., 2020 4, : : Drug Metabolism And Pharmacokinetics. 35, 2, p. 238-243 6 p.

研究成果: Article

2019

Synthesis and antitumor activity of novel pyridinium fullerene derivatives

Yasuno, T., Ohe, T., Ikeda, H., Takahashi, K., Nakamura, S. & Mashino, T., 2019 1 1, : : International journal of nanomedicine. 14, p. 6325-6337 13 p.

研究成果: Article

公開
2 引用 (Scopus)
2018
4 引用 (Scopus)

Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation

Ohe, T., Umezawa, R., Kitagawara, Y., Yasuda, D., Takahashi, K., Nakamura, S., Abe, A., Sekine, S., Ito, K., Okunushi, K., Morio, H., Furihata, T., Anzai, N. & Mashino, T., 2018 1 1, (Accepted/In press) : : Bioorganic and Medicinal Chemistry Letters.

研究成果: Article

1 引用 (Scopus)
2017

Alpha-tocopherol attenuates the anti-tumor activity of crizotinib against cells transformed by NPM-ALK

Uchihara, Y., Ueda, F., Tago, K., Nakazawa, Y., Ohe, T., Mashino, T., Yokota, S., Kasahara, T., Tamura, H. & Funakoshi-Tago, M., 2017 8, : : PloS one. 12, 8, e0183003.

研究成果: Article

7 引用 (Scopus)

Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor

Yasuda, D., Yuasa, A., Obata, R., Nakajima, M., Takahashi, K., Ohe, T., Ichimura, Y., Komatsu, M., Yamamoto, M., Imamura, R., Kojima, H., Okabe, T., Nagano, T. & Mashino, T., 2017 11 15, : : Bioorganic and Medicinal Chemistry Letters. 27, 22, p. 5006-5009 4 p.

研究成果: Article

14 引用 (Scopus)
2016
3 引用 (Scopus)
1 引用 (Scopus)
6 引用 (Scopus)

P62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming

Saito, T., Ichimura, Y., Taguchi, K., Suzuki, T., Mizushima, T., Takagi, K., Hirose, Y., Nagahashi, M., Iso, T., Fukutomi, T., Ohishi, M., Endo, K., Uemura, T., Nishito, Y., Okuda, S., Obata, M., Kouno, T., Imamura, R., Tada, Y., Obata, R. および18人, Yasuda, D., Takahashi, K., Fujimura, T., Pi, J., Lee, M. S., Ueno, T., Ohe, T., Mashino, T., Wakai, T., Kojima, H., Okabe, T., Nagano, T., Motohashi, H., Waguri, S., Soga, T., Yamamoto, M., Tanaka, K. & Komatsu, M., 2016 6 27, : : Nature communications. 7, 12030.

研究成果: Article

99 引用 (Scopus)

Potential Suppressive Effects of Two C60 Fullerene Derivatives on Acquired Immunity

Hirai, T., Yoshioka, Y., Udaka, A., Uemura, E., Ohe, T., Aoshima, H., Gao, J. Q., Kokubo, K., Oshima, T., Nagano, K., Higashisaka, K., Mashino, T. & Tsutsumi, Y., 2016 12 1, : : Nanoscale Research Letters. 11, 1, 449.

研究成果: Article

4 引用 (Scopus)
1 引用 (Scopus)

Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity

Yasuda, D., Nakajima, M., Yuasa, A., Obata, R., Takahashi, K., Ohe, T., Ichimura, Y., Komatsu, M., Yamamoto, M., Imamura, R., Kojima, H., Okabe, T., Nagano, T. & Mashino, T., 2016 12 15, : : Bioorganic and Medicinal Chemistry Letters. 26, 24, p. 5956-5959 4 p.

研究成果: Article

22 引用 (Scopus)
2015

Novel bioactivation pathway of benzbromarone mediated by cytochrome P450

Kitagawara, Y., Ohe, T., Tachibana, K., Takahashi, K., Nakamura, S. & Mashino, T., 2015 9 1, : : Drug Metabolism and Disposition. 43, 9, p. 1303-1306 4 p.

研究成果: Article

10 引用 (Scopus)
13 引用 (Scopus)
2014

Effect of chemical modification on the ability of pyrrolidinium fullerene to induce apoptosis of cells transformed by JAK2 V617F mutant

Funakoshi-Tago, M., Tsukada, M., Watanabe, T., Mameda, Y., Tago, K., Ohe, T., Nakamura, S., Mashino, T. & Kasahara, T., 2014 5, : : International Immunopharmacology. 20, 1, p. 258-263 6 p.

研究成果: Article

5 引用 (Scopus)

Pyrrolidinium fullerene induces apoptosis by activation of procaspase-9 via suppression of Akt in primary effusion lymphoma

Watanabe, T., Nakamura, S., Ono, T., Ui, S., Yagi, S., Kagawa, H., Watanabe, H., Ohe, T., Mashino, T. & Fujimuro, M., 2014 8 15, : : Biochemical and Biophysical Research Communications. 451, 1, p. 93-100 8 p.

研究成果: Article

15 引用 (Scopus)
2013

Anti-Influenza Activity of C60 Fullerene Derivatives

Shoji, M., Takahashi, E., Hatakeyama, D., Iwai, Y., Morita, Y., Shirayama, R., Echigo, N., Kido, H., Nakamura, S., Mashino, T., Okutani, T. & Kuzuhara, T., 2013 6 13, : : PloS one. 8, 6, e66337.

研究成果: Article

41 引用 (Scopus)
11 引用 (Scopus)

Synthesis, radical scavenging activity and structure-activity relationship of uric acid analogs

Yasuda, D., Takahashi, K., Kakinoki, T., Tanaka, Y., Ohe, T., Nakamura, S. & Mashino, T., 2013 3 1, : : MedChemComm. 4, 3, p. 527-529 3 p.

研究成果: Article

12 引用 (Scopus)
2012

Fullerene derivative prevents cellular transformation induced by JAK2 V617F mutant through inhibiting c-Jun N-terminal kinase pathway

Funakoshi-Tago, M., Nagata, T., Tago, K., Tsukada, M., Tanaka, K., Nakamura, S., Mashino, T. & Kasahara, T., 2012 11 1, : : Cellular Signalling. 24, 11, p. 2024-2034 11 p.

研究成果: Article

8 引用 (Scopus)

Impairment of heme biosynthesis induces short circadian period in body temperature rhythms in mice

Iwadate, R., Satoh, Y., Watanabe, Y., Kawai, H., Kudo, N., Kawashima, Y., Mashino, T. & Mitsumoto, A., 2012 7 1, : : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 303, 1, p. R8-R18

研究成果: Article

5 引用 (Scopus)
2011

Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin

Funakoshi-Tago, M., Nakamura, K., Tago, K., Mashino, T. & Kasahara, T., 2011 9 1, : : International Immunopharmacology. 11, 9, p. 1150-1159 10 p.

研究成果: Article

146 引用 (Scopus)

Ipso substitution of bisphenol A catalyzed by microsomal cytochrome P450 and enhancement of estrogenic activity

Nakamura, S., Tezuka, Y., Ushiyama, A., Kawashima, C., Kitagawara, Y., Takahashi, K., Ohta, S. & Mashino, T., 2011 5 30, : : Toxicology Letters. 203, 1, p. 92-95 4 p.

研究成果: Article

40 引用 (Scopus)

Isolation and structural identification of a direct-acting mutagen derived from N-nitroso-N-methylpentylamine and Fenton's reagent with copper ion

Miura, M., Inami, K., Yoshida, M., Yamaguchi, K., Mashino, T. & Mochizuki, M., 2011 9 15, : : Bioorganic and Medicinal Chemistry. 19, 18, p. 5693-5697 5 p.

研究成果: Article

6 引用 (Scopus)
2010
24 引用 (Scopus)
33 引用 (Scopus)
2009
23 引用 (Scopus)

Fullerene nanowhiskers and related fullerene nanomaterials

Miyazawa, K., Kato, R., Saito, K., Kizuka, T., Mashino, T. & Nakamura, S., 2009 1 1, : : Journal of Physics: Conference Series. 159, 012007.

研究成果: Article

3 引用 (Scopus)
63 引用 (Scopus)

In vitro free radical scavenging activity of platinum nanoparticles

Watanabe, A., Kajita, M., Kim, J., Kanayama, A., Takahashi, K., Mashino, T. & Miyamoto, Y., 2009 11 9, : : Nanotechnology. 20, 45, 455105.

研究成果: Article

95 引用 (Scopus)
38 引用 (Scopus)

Licochalcone A significantly suppresses LPS signaling pathway through the inhibition of NF-κB p65 phosphorylation at serine 276

Furusawa, J. I., Funakoshi-Tago, M., Tago, K., Mashino, T., Inoue, H., Sonoda, Y. & Kasahara, T., 2009 5 1, : : Cellular Signalling. 21, 5, p. 778-785 8 p.

研究成果: Article

55 引用 (Scopus)

Pyrrolidinium-type fullerene derivative-induced apoptosis by the generation of reactive oxygen species in HL-60 cells

Nishizawa, C., Hashimoto, N., Yokoo, S., Funakoshi-Tago, M., Kasahara, T., Takahashi, K., Nakamura, S. & Mashino, T., 2009, : : Free Radical Research. 43, 12, p. 1240-1247 8 p.

研究成果: Article

29 引用 (Scopus)
2008

2,2′-Pyridoin derivatives protect HL-60 cells against oxidative stress

Hatanaka, M., Nishizawa, C., Kakinoki, T., Takahashi, K., Nakamura, S. & Mashino, T., 2008 10 1, : : Bioorganic and Medicinal Chemistry Letters. 18, 19, p. 5290-5293 4 p.

研究成果: Article

8 引用 (Scopus)

C60 nanowhisker field-effect-transistor application for nano-electronics

Ogawa, K. I., Aoki, N., Miyazawa, K., Nakamura, S., Mashino, T., Bird, J. P. & Ochiai, Y., 2008 1 22, : : Japanese journal of applied physics. 47, 1 PART 2, p. 501-504 4 p.

研究成果: Article

9 引用 (Scopus)

Licochalcone A is a potent inhibitor of TEL-Jak2-mediated transformation through the specific inhibition of Stat3 activation

Funakoshi-Tago, M., Tago, K., Nishizawa, C., Takahashi, K., Mashino, T., Iwata, S., Inoue, H., Sonoda, Y. & Kasahara, T., 2008 12 15, : : Biochemical Pharmacology. 76, 12, p. 1681-1693 13 p.

研究成果: Article

31 引用 (Scopus)
2007

DMPO-OH radical formation from 5,5-dimethyl-1-pyrroline N-oxide (DMPO) in hot water

Shoji, T., Li, L., Abe, Y., Ogata, M., Ishimoto, Y., Gonda, R., Mashino, T., Mochizuki, M., Uemoto, M. & Miyata, N., 2007 2, : : Analytical Sciences. 23, 2, p. 219-221 3 p.

研究成果: Article

12 引用 (Scopus)

Iron-chelating agents never suppress Fenton reaction but participate in quenching spin-trapped radicals

Li, L., Abe, Y., Kanagawa, K., Shoji, T., Mashino, T., Mochizuki, M., Tanaka, M. & Miyata, N., 2007 9 19, : : Analytica Chimica Acta. 599, 2, p. 315-319 5 p.

研究成果: Article

37 引用 (Scopus)

Novel metabolic pathways of p-n-nonylphenol catalyzed by cytochrome P450 and estrogen receptor binding activity of new metabolites

Tezuka, Y., Takahashi, K., Suzuki, T., Kitamura, S., Ohta, S., Nakamura, S. & Mashino, T., 2007 10, : : Journal of Health Science. 53, 5, p. 552-561 10 p.

研究成果: Article

17 引用 (Scopus)

Solubilization of dipropofol, an antibacterial agent, using saccharide and ascorbic acid

Ogata, M., Oka, K., Seki, M., Hoshi, M., Takatsu, H., Mashino, T., Urano, S. & Endo, T., 2007 8 1, : : Biological and Pharmaceutical Bulletin. 30, 8, p. 1565-1568 4 p.

研究成果: Article

3 引用 (Scopus)
2006

Metabolic conversion of 24-methyl-Δ25-cholesterol to 24-methylcholesterol in higher plants

Takahashi, K., Nasu, K., Mashino, T., Morisaki, M., Hara, N. & Fujimoto, Y., 2006 2 1, : : Bioorganic and Medicinal Chemistry. 14, 3, p. 732-738 7 p.

研究成果: Article

1 引用 (Scopus)

Structural characterization of room-temperature synthesized fullerene nanowhiskers

Miyazawa, K., Minato, J. I., Mashino, T., Nakamura, S., Fujino, M. & Suga, T., 2006 6 14, : : Nukleonika. 51, SUPPL. 1, p. S41-S48

研究成果: Article

10 引用 (Scopus)
2005

Biodegradable polymers in chondrogenesis of human articular chondrocytes

Banu, N., Banu, Y., Sakai, M., Mashino, T. & Tsuchiya, T., 2005 9 1, : : Journal of Artificial Organs. 8, 3, p. 184-191 8 p.

研究成果: Article

14 引用 (Scopus)

Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives

Mashino, T., Shimotohno, K., Ikegami, N., Nishikawa, D., Okuda, K., Takahashi, K., Nakamura, S. & Mochizuki, M., 2005 2 15, : : Bioorganic and Medicinal Chemistry Letters. 15, 4, p. 1107-1109 3 p.

研究成果: Article

140 引用 (Scopus)

Preparation and antioxidant activity of α-pyridoin and its derivatives

Hatanaka, M., Takahashi, K., Nakamura, S. & Mashino, T., 2005 12 15, : : Bioorganic and Medicinal Chemistry. 13, 24, p. 6763-6770 8 p.

研究成果: Article

30 引用 (Scopus)
2004

An HPLC assay of hydroxyl radicals by the hydroxylation reaction of terephthalic acid

Linxiang, L., Abe, Y., Nagasawa, Y., Kudo, R., Usui, N., Imai, K., Mashino, T., Mochizuki, M. & Miyata, N., 2004 9 1, : : Biomedical Chromatography. 18, 7, p. 470-474 5 p.

研究成果: Article

67 引用 (Scopus)