• 4920 引用
  • 31 h指数
1993 …2020

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 4920 引用
  • 31 h指数
  • 51 Article
  • 3 Chapter
  • 3 Review article
  • 1 Comment/debate
2020
公開
2019
公開
7 引用 (Scopus)
2016
5 引用 (Scopus)
2 引用 (Scopus)
2015

MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells

Tsuyama, J., Bunt, J., Richards, L. J., Iwanari, H., Mochizuki, Y., Hamakubo, T., Shimazaki, T. & Okano, H., 2015 9 8, : : Stem Cell Reports. 5, 3, p. 365-377 13 p.

研究成果: Article

24 引用 (Scopus)
2014
2 引用 (Scopus)

The miR-17/106-p38 axis is a key regulator of the neurogenic-to-gliogenic transition in developing neural stem/progenitor cells

Naka-Kaneda, H., Nakamura, S., Igarashi, M., Aoi, H., Kanki, H., Tsuyama, J., Tsutsumi, S., Aburatani, H., Shimazaki, T. & Okano, H., 2014 1 28, : : Proceedings of the National Academy of Sciences of the United States of America. 111, 4, p. 1604-1609 6 p.

研究成果: Article

36 引用 (Scopus)
2013

Regulatory mechanisms underlying the neurogenesis-to-gliogenesis switch by neural stem cells

Shimazaki, T., 2013 1 1, Cortical Development: Neural Diversity and Neocortical Organization. Springer Japan, p. 63-88 26 p.

研究成果: Chapter

1 引用 (Scopus)
2012

Generation of neural cells from pluripotent stem cells

Shimazaki, T. & Okano, H., 2012 1 1, Nuclear Reprogramming and Stem Cells. Humana Press Inc., p. 127-140 14 p.

研究成果: Chapter

2010

Efficient generation of mature cerebellar Purkinje cells from mouse embryonic stem cells

Tao, O., Shimazaki, T., Okada, Y., Naka, H., Kohda, K., Yuzaki, M., Mizusawa, H. & Okano, H., 2010 2 1, : : Journal of neuroscience research. 88, 2, p. 234-247 14 p.

研究成果: Article

20 引用 (Scopus)

FRS2α regulates Erk levels to control a self-renewal target Hes1 and proliferation of FGF-responsive neural stem/progenitor cells

Sato, T., Shimazaki, T., Naka, H., Fukami, S. I., Satoh, Y., Okano, H., Irit, L., Schlessinger, J. & Gotoh, N., 2010 9, : : Stem Cells. 28, 9, p. 1661-1673 13 p.

研究成果: Article

25 引用 (Scopus)

Regulation of adult neural progenitor cells by Galectin-1/β1 Integrin interaction

Sakaguchi, M., Imaizumi, Y., Shingo, T., Tada, H., Hayama, K., Yamada, O., Morishita, T., Kadoya, T., Uchiyama, N., Shimazaki, T., Kuno, A., Poirier, F., Hirabayashi, J., Sawamoto, K. & Okano, H., 2010 6, : : Journal of Neurochemistry. 113, 6, p. 1516-1524 9 p.

研究成果: Article

21 引用 (Scopus)
23 引用 (Scopus)
2009

Evaluation of human fetal neural stem/progenitor cells as a source for cell replacement therapy for neurological disorders: Properties and tumorigenicity after long-term in vitro maintenance

Ogawa, D., Okada, Y., Nakamura, M., Kanemura, Y., Okano, H. J., Matsuzaki, Y., Shimazaki, T., Ito, M., Ikeda, E., Tamiya, T., Nagao, S. & Okano, H., 2009 2 1, : : Journal of neuroscience research. 87, 2, p. 307-317 11 p.

研究成果: Article

23 引用 (Scopus)
2008

[Mammalian neural stem cells].

Shimazaki, T. & Okano, H., 2008 3 1, : : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 53, 4 Suppl, p. 311-317 7 p.

研究成果: Review article

3 引用 (Scopus)

Consequence of the loss of Sox2 in the developing brain of the mouse

Miyagi, S., Masui, S., Niwa, H., Saito, T., Shimazaki, T., Okano, H., Nishimoto, M., Muramatsu, M., Iwama, A. & Okuda, A., 2008 8 6, : : FEBS Letters. 582, 18, p. 2811-2815 5 p.

研究成果: Article

67 引用 (Scopus)
152 引用 (Scopus)
45 引用 (Scopus)

Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells

Okada, Y., Matsumoto, A., Shimazaki, T., Enoki, R., Koizumi, A., Ishii, S., Itoyama, Y., Sobue, G. & Okano, H., 2008 12 1, : : Stem Cells. 26, 12, p. 3086-3098 13 p.

研究成果: Article

123 引用 (Scopus)
2007
16 引用 (Scopus)

Leptin suppresses ghrelin-induced activation of neuropeptide Y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway

Kohno, D., Nakata, M., Maekawa, F., Fujiwara, K., Maejima, Y., Kuramochi, M., Shimazaki, T., Okano, H., Onaka, T. & Yada, T., 2007 5, : : Endocrinology. 148, 5, p. 2251-2263 13 p.

研究成果: Article

105 引用 (Scopus)

Simian fetal brain progenitor cells for studying viral neuropathogenesis

Iwata, N., Yoshida, H., Tobiume, M., Ono, F., Shimazaki, T., Sata, T. & Nakajima, N., 2007 1 1, : : Journal of NeuroVirology. 13, 1, p. 11-22 12 p.

研究成果: Article

2 引用 (Scopus)
16 引用 (Scopus)
2006

A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells

Sakaguchi, M., Shingo, T., Shimazaki, T., Okano, H. J., Shiwa, M., Ishibashi, S., Oguro, H., Ninomiya, M., Kadoya, T., Horie, H., Shibuya, A., Mizusawa, H., Poirier, F., Nakauchi, H., Sawamoto, K. & Okano, H., 2006 5 2, : : Proceedings of the National Academy of Sciences of the United States of America. 103, 18, p. 7112-7117 6 p.

研究成果: Article

133 引用 (Scopus)

Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury

Okada, S., Nakamura, M., Katoh, H., Miyao, T., Shimazaki, T., Ishii, K., Yamane, J., Yoshimura, A., Iwamoto, Y., Toyama, Y. & Okano, H., 2006 7 1, : : Nature medicine. 12, 7, p. 829-834 6 p.

研究成果: Article

590 引用 (Scopus)

Generation of neural cells from embryonic stem cells

Shimazaki, T., Okada, Y., Yoshizaki, T. & Okano, H., 2006 11 1, : : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 51, 13, p. 1854-1861 8 p.

研究成果: Review article

Histopathological and behavioral improvement of murine mucopolysaccharidosis type VII by intracerebral transplantation of neural stem cells

Fukuhara, Y., Li, X. K., Kitazawa, Y., Inagaki, M., Matsuoka, K., Kosuga, M., Kosaki, R., Shimazaki, T., Endo, H., Umezawa, A., Okano, H., Takahashi, T. & Okuyama, T., 2006 3 1, : : Molecular Therapy. 13, 3, p. 548-555 8 p.

研究成果: Article

14 引用 (Scopus)

Neural stem cells: Isolation and self-renewal

Okano, H., Kohyama, J., Ohba, H., Sakaguchi, M., Tokunaga, A., Shimazaki, T. & Okano, H. J., 2006 1 1, Tissue Stem Cells. CRC Press, p. 55-70 16 p.

研究成果: Chapter

2005

Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart

Tomita, Y., Matsumura, K., Wakamatsu, Y., Matsuzaki, Y., Shibuya, I., Kawaguchi, H., Ieda, M., Kanakubo, S., Shimazaki, T., Ogawa, S., Osumi, N., Okano, H. & Fukuda, K., 2005 9 26, : : Journal of Cell Biology. 170, 7, p. 1135-1146 12 p.

研究成果: Article

252 引用 (Scopus)

Comparative functional genomics revealed conservation and diversification of three enhancers of the isl1 gene for motor and sensory neuron-specific expression

Uemura, O., Okada, Y., Ando, H., Guedj, M., Higashijima, S. I., Shimazaki, T., Chino, N., Okano, H. & Okamoto, H., 2005 2 15, : : Developmental Biology. 278, 2, p. 587-606 20 p.

研究成果: Article

101 引用 (Scopus)

Erratum: Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells (Nature Biotechnology (2005) 23 (607-611))

Yuasa, S., Itabashi, Y., Koshimizu, U., Tanaka, T., Sugimura, K., Kinoshita, M., Hattori, F., Fukami, S. I., Shimazaki, T., Ogawa, S., Okano, H. & Fukuda, K., 2005 12 1, : : Nature Biotechnology. 23, 7, 1 p.

研究成果: Comment/debate

2 引用 (Scopus)

Essential role of Shp2-binding sites on FRS2α for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells

Yamamoto, S., Yoshino, I., Shimazaki, T., Murohashi, M., Hevner, R. F., Lax, I., Okano, H., Shibuya, M., Schlessinger, J. & Gotoh, N., 2005 11 1, : : Proceedings of the National Academy of Sciences of the United States of America. 102, 44, p. 15983-15988 6 p.

研究成果: Article

53 引用 (Scopus)

Inhibition of glioma cell proliferation by neural stem cell factor

Suzuki, T., Izumoto, S., Wada, K., Fujimoto, Y., Maruno, M., Yamasaki, M., Kanemura, Y., Shimazaki, T., Okano, H. & Yoshimine, T., 2005 9 1, : : Journal of Neuro-Oncology. 74, 3, p. 233-239 7 p.

研究成果: Article

20 引用 (Scopus)

Prospective characterization of neural stem cells by flow cytometry analysis using a combination of surface markers

Nagato, M., Heike, T., Kato, T., Yamanaka, Y., Yoshimoto, M., Shimazaki, T., Okano, H. & Nakahata, T., 2005 5 15, : : Journal of neuroscience research. 80, 4, p. 456-466 11 p.

研究成果: Article

64 引用 (Scopus)

Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells

Yuasa, S., Itabashi, Y., Koshimizu, U., Tanaka, T., Sugimura, K., Kinoshita, M., Hattori, F., Fukami, S. I., Shimazaki, T., Okano, H., Ogawa, S. & Fukuda, K., 2005, : : Nature Biotechnology. 23, 5, p. 607-611 5 p.

研究成果: Article

236 引用 (Scopus)
2004

Blockade of Interleukin-6 Receptor Suppresses Reactive Astrogliosis and Ameliorates Functional Recovery in Experimental Spinal Cord Injury

Okada, S., Nakamura, M., Mikami, Y., Shimazaki, T., Mihara, M., Ohsugi, Y., Iwamoto, Y., Yoshizaki, K., Kishimoto, T., Toyama, Y. & Okano, H., 2004 4 15, : : Journal of neuroscience research. 76, 2, p. 265-276 12 p.

研究成果: Article

180 引用 (Scopus)

Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina

Ozawa, Y., Nakao, K., Shimazaki, T., Takeda, J., Akira, S., Ishihara, K., Hirano, T., Oguchi, Y. & Okano, H., 2004 6 1, : : Molecular and Cellular Neuroscience. 26, 2, p. 258-270 13 p.

研究成果: Article

41 引用 (Scopus)

Human neural stem/progenitor cells, expanded in long-term neurosphere culture, promote functional recovery after focal ischemia in Mongolian gerbils

Ishibashi, S., Sakaguchi, M., Kuroiwa, T., Yamasaki, M., Kanemura, Y., Shizuko, I., Shimazaki, T., Onodera, M., Okano, H. & Mizusawa, H., 2004 10 15, : : Journal of neuroscience research. 78, 2, p. 215-223 9 p.

研究成果: Article

139 引用 (Scopus)
67 引用 (Scopus)

Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells

Yoshizaki, T., Inaji, M., Kouike, H., Shimazaki, T., Sawamoto, K., Ando, K., Date, I., Kobayashi, K., Suhara, T., Uchiyama, Y. & Okano, H., 2004 6 3, : : Neuroscience Letters. 363, 1, p. 33-37 5 p.

研究成果: Article

75 引用 (Scopus)

Meteorin: A secreted protein that regulates glial cell differentiation and promotes axonal extension

Nishino, J., Yamashita, K., Hashiguchi, H., Fujii, H., Shimazaki, T. & Hamada, H., 2004 5 5, : : EMBO Journal. 23, 9, p. 1998-2008 11 p.

研究成果: Article

64 引用 (Scopus)
244 引用 (Scopus)
2003

Biology and clinical application of neural stem cells

Shimazaki, T., 2003 12 30, : : Hormone Research. 60, SUPPL. 3, p. 1-9 9 p.

研究成果: Article

17 引用 (Scopus)

Glycoprotein 130 signaling regulates Notch1 expression and activation in the self-renewal of mammalian forebrain neural stem cells

Chojnacki, A., Shimazaki, T., Gregg, C., Weinmaster, G. & Weiss, S., 2003 3 1, : : Journal of Neuroscience. 23, 5, p. 1730-1741 12 p.

研究成果: Article

143 引用 (Scopus)

Hepatocyte growth factor promotes proliferation and neuronal differentiation of neural stem cells from mouse embryos

Kokuzawa, J., Yoshimura, S., Kitajima, H., Shinoda, J., Kaku, Y., Iwama, T., Morishita, R., Shimazaki, T., Okano, H., Kunisada, T. & Sakai, N., 2003 9 1, : : Molecular and Cellular Neuroscience. 24, 1, p. 190-197 8 p.

研究成果: Article

40 引用 (Scopus)

Transplantation of neural stem cells into epileptic brain

Matsumoto, Y., Sindo, A., Kawai, N., Kunishio, K., Nagao, S., Miyazaki, T., Itano, T., Okada, Y., Shimazaki, T. & Okano, H., 2003 6 1, : : International Congress Series. 1252, C, p. 489-492 4 p.

研究成果: Article

3 引用 (Scopus)
2002

Flow cytometric analysis of neural stem cells in the developing and adult mouse brain

Murayama, A., Matsuzaki, Y., Kawaguchi, A., Shimazaki, T. & Okano, H., 2002 9 15, : : Journal of neuroscience research. 69, 6, p. 837-847 11 p.

研究成果: Article

106 引用 (Scopus)

Isolation and transplantation of dopaminergic neurons and neural stem cells

Okano, H., Yoshizaki, T., Shimazaki, T. & Sawamoto, K., 2002 10 1, : : Parkinsonism and Related Disorders. 9, 1, p. 23-28 6 p.

研究成果: Article

16 引用 (Scopus)
2001

Brain from bone: Efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent

Kohyama, J., Abe, H., Shimazaki, T., Koizumi, A., Nakashima, K., Gojo, S., Taga, T., Okano, H., Hata, J. I. & Umezawa, A., 2001 10, : : Differentiation. 68, 4-5, p. 235-244 10 p.

研究成果: Article

270 引用 (Scopus)