Tetsuji Kamata

2021

Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin αIIbβ3 for ligand binding

Nesi, D., Bush, M., Coller, B. S., Li, J., Kamata, T., Handa, M. & Walz, T., 2021 3 24, In: Blood Advances. 5, 7, p. 1781-1790 10 p.

研究成果: Article › 査読

Open Access

2013

Epitope Mapping for Monoclonal Antibody Reveals the Activation Mechanism for αVβ3 Integrin

Kamata, T., Handa, M., Takakuwa, S., Sato, Y., Kawai, Y., Ikeda, Y. & Aiso, S., 2013 6 20, In: PloS one. 8, 6, e66096.

研究成果: Article › 査読

6 被引用数 (Scopus)

2010

Structural requirements for activation in αIIbβ3 integrin

Kamata, T., Handa, M., Ito, S., Sato, Y., Ohtani, T., Kawai, Y., Ikeda, Y. & Aiso, S., 2010 12 3, In: Journal of Biological Chemistry. 285, 49, p. 38428-38437 10 p.

研究成果: Article › 査読

20 被引用数 (Scopus)

2008

Key interactions in integrin ectodomain responsible for global conformational change detected by elastic network normal-mode analysis

Matsumoto, A., Kamata, T., Takagi, J., Iwasaki, K. & Yura, K., 2008 9 15, In: Biophysical Journal. 95, 6, p. 2895-2908 14 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

2005

Membrane-proximal α/β stalk interactions differentially regulate integrin activation

Kamata, T., Handa, M., Sato, Y., Ikeda, Y. & Aiso, S., 2005 7 1, In: Journal of Biological Chemistry. 280, 26, p. 24775-24783 9 p.

研究成果: Article › 査読

41 被引用数 (Scopus)

2004

Critical cysteine residues for regulation of integrin αIIbβ3 are clustered in the epidermal growth factor domains of the β3 subunit

Kamata, T., Ambo, H., Puzon-McLaughlin, W., Tieu, K. K., Handa, M., Ikeda, Y. & Takada, Y., 2004 3 15, In: Biochemical Journal. 378, 3, p. 1079-1082 4 p.

研究成果: Article › 査読

58 被引用数 (Scopus)

2002

The role of the CPNKEKEC sequence in the β₂ subunit I domain in regulation of integrin α_Lβ₂ (LFA-1)

Kamata, T., Tieu, K. K., Tarui, T., Puzon-McLaughlin, W., Hogg, N. & Takada, Y., 2002 3 1, In: Journal of Immunology. 168, 5, p. 2296-2301 6 p.

研究成果: Article › 査読

Open Access

46 被引用数 (Scopus)

2001

Amino Acid Residues in the α_IIb Subunit that Are Critical for Ligand Binding to Integrin α_IIbβ₃ Are Clustered in the β-Propeller Model

Kamata, T., Tieu, K. K., Irie, A., Springer, T. A. & Takada, Y., 2001 11 23, In: Journal of Biological Chemistry. 276, 47, p. 44275-44283 9 p.

研究成果: Article › 査読

71 被引用数 (Scopus)

Platelet integrin αIIbβ3-ligand interactions: What can we learn from the structure?

Kamata, T. & Takada, Y., 2001, In: International journal of hematology. 74, 4, p. 382-389 8 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

Weitz-Schmidt, G., Welzenbach, K., Brinkmann, V., Kamata, T., Kallen, J., Bruns, C., Cottens, S., Takada, Y. & Hommel, U., 2001, In: Nature medicine. 7, 6, p. 687-692 6 p.

研究成果: Article › 査読

936 被引用数 (Scopus)

2000

Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin α(IIb)β₃

Puzon-McLaughlin, W., Kamata, T. & Takada, Y., 2000 3 17, In: Journal of Biological Chemistry. 275, 11, p. 7795-7802 8 p.

研究成果: Article › 査読

89 被引用数 (Scopus)

1999

Interaction between collagen and the α₂ I-domain of integrin αβ1: Critical role of conserved residues in the metal ion-dependent adhesion site (MIDAS) region

Kamata, T., Liddington, R. C. & Takada, Y., 1999 11 5, In: Journal of Biological Chemistry. 274, 45, p. 32108-32111 4 p.

研究成果: Article › 査読

42 被引用数 (Scopus)

1998

Novel point mutations in the αIIb subunit (Phe²⁸⁹ → Ser, Glu³²⁴ → Lys and Gln⁷⁴⁷ → Pro) causing thrombasthenic phenotypes in four Japanese patients

Ambo, H., Kamata, T., Handa, M., Kawai, Y., Oda, A., Murata, M., Takada, Y. & Ikeda, Y., 1998, In: British Journal of Haematology. 102, 3, p. 829-840 12 p.

研究成果: Article › 査読

21 被引用数 (Scopus)

Specific interaction of the recombinant disintegrin-like domain of MDC- 15 (Metargidin, ADAM-15) with integrin αvβ3

Zhang, X. P., Kamata, T., Yokoyama, K., Puzon-McLaughlin, W. & Takada, Y., 1998 3 27, In: Journal of Biological Chemistry. 273, 13, p. 7345-7350 6 p.

研究成果: Article › 査読

194 被引用数 (Scopus)

Three novel integrin β3 subunit missense mutations (H280P, C560F, and G579S) in thrombasthenia, including one (H280P) prevalent in Japanese patients

Ambo, H., Kamata, T., Handa, M., Taki, M., Kuwajima, M., Kawai, Y., Oda, A., Murata, M., Takada, Y., Watanabe, K. & Ikeda, Y., 1998 10 29, In: Biochemical and Biophysical Research Communications. 251, 3, p. 763-768 6 p.

研究成果: Article › 査読

39 被引用数 (Scopus)

1997

Changing ligand specificities of αvβ1 and αvβ3 integrins by swapping a short diverse sequence of the β subunit

Takagi, J., Kamata, T., Meredith, J., Puzon-McLaughlin, W. & Takada, Y., 1997 8 8, In: Journal of Biological Chemistry. 272, 32, p. 19794-19800 7 p.

研究成果: Article › 査読

109 被引用数 (Scopus)

Echovirus 1 interaction with the human very late antigen-2 (integrin α2β1) I domain: Identification of two independent virus contact sites distinct from the metal ion-dependent adhesion site

King, S. L., Kamata, T., Cunningham, J. A., Emsley, J., Liddington, R. C., Takada, Y. & Bergelson, J. M., 1997 11 7, In: Journal of Biological Chemistry. 272, 45, p. 28518-28522 5 p.

研究成果: Article › 査読

37 被引用数 (Scopus)

Multiple loop structures critical for ligand binding of the integrin α4 subunit in the upper face of the β-propeller mode

Irie, A., Kamata, T. & Takada, Y., 1997 7 8, In: Proceedings of the National Academy of Sciences of the United States of America. 94, 14, p. 7198-7203 6 p.

研究成果: Article › 査読

Open Access

60 被引用数 (Scopus)

1996

Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells

Huang, S., Kamata, T., Takada, Y., Ruggeri, Z. M. & Nemerow, G. R., 1996, In: Journal of Virology. 70, 7, p. 4502-4508 7 p.

研究成果: Article › 査読

Open Access

211 被引用数 (Scopus)

A novel regulatory epitope defined by a murine monoclonal antibody to the platelet GPIIb-IIIa complex (αIIbβ3 integrin)

Tokuhira, M., Handa, M., Kamata, T., Oda, A., Katayama, M., Tomiyama, Y., Murata, M., Kawai, Y., Watanabe, K. & Ikeda, Y., 1996 12, In: Thrombosis and Haemostasis. 76, 6, p. 1038-1046 9 p.

研究成果: Article › 査読

52 被引用数 (Scopus)

Critical residues of integrin αIIb subunit for binding of αIIbβ3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3)

Kamata, T., Irie, A., Tokuhira, M. & Takada, Y., 1996, In: Journal of Biological Chemistry. 271, 31, p. 18610-18615 6 p.

研究成果: Article › 査読

79 被引用数 (Scopus)

1995

Critical amino acid residues for ligand binding are clustered in a predicted β-turn of the third N-terminal repeat in the integrin α4 and α5 subunits

Irie, A., Kamata, T., Puzon-McLaughlin, W. & Takada, Y., 1995, In: EMBO Journal. 14, 22, p. 5550-5556 7 p.

研究成果: Article › 査読

89 被引用数 (Scopus)

Critical threonine and aspartic acid residues within the I domains of β2 integrins for interactions with intercellular adhesion molecule 1 (ICAM-1) and C3bi

Kamata, T., Wright, R. & Takada, Y., 1995, In: Journal of Biological Chemistry. 270, 21, p. 12531-12535 5 p.

研究成果: Article › 査読

85 被引用数 (Scopus)

Identification of putative ligand-binding sites of the integrin α4β1 (VLA-4, CD49d/CD29)

Kamata, T., Puzon, W. & Takada, Y., 1995, In: Biochemical Journal. 305, 3, p. 945-951 7 p.

研究成果: Article › 査読

121 被引用数 (Scopus)

Platelet unresponsiveness to collagen: Involvement of glycoprotein Ia-IIa (α₂β₁ integrin) deficiency associated with a myeloproliferative disorder

Handa, M., Watanabe, K., Kawai, Y., Kamata, T., Koyama, T., Nagai, H. & Ikeda, Y., 1995, In: Thrombosis and Haemostasis. 73, 3, p. 521-528 8 p.

研究成果: Article › 査読

83 被引用数 (Scopus)

1994

Direct binding of collagen to the I domain of integrin α2β1 (VLA-2, CD49b/CD29) in a divalent cation-independent manner

Kamata, T. & Takada, Y., 1994 10 21, In: Journal of Biological Chemistry. 269, 42, p. 26006-26010 5 p.

研究成果: Article › 査読

140 被引用数 (Scopus)

Identification of putative ligand binding sites within I domain of integrin α2β1 (VLA-2, CD49b/CD29)

Kamata, T., Puzon, W. & Takada, Y., 1994 4 1, In: Journal of Biological Chemistry. 269, 13, p. 9659-9663 5 p.

研究成果: Article › 査読

147 被引用数 (Scopus)

Rapid improvement of coagulopathy by all‐trans retinoic acid in acute promyelocytic leukemia

Kawai, Y., Watanabe, K., Kizaki, M., Murata, M., Kamata, T., Uchida, H., Moriki, T., Yokoyama, K., Tokuhira, M., Nakajima, H., Handa, M. & Ikeda, Y., 1994 7, In: American journal of hematology. 46, 3, p. 184-188 5 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

1993

Transmembrane calcium influx associated with von Willebrand factor binding to GP Ib in the initiation of shear-induced platelet aggregation

Ikeda, Y., Handa, M., Kamata, T., Kawano, K., Kawai, Y., Watanabe, K., Kawakami, K., Sakai, K., Fukuyama, M., Itagaki, I., Yoshioka, A. & Ruggeri, Z. M., 1993, In: Thrombosis and Haemostasis. 69, 5, p. 496-502 7 p.

研究成果: Article › 査読

159 被引用数 (Scopus)

1992

Extramedullary diseases as presenting features of aleukemic acute monocytic leukemia

Hayashida, T., Araki, Y., Kawano, K., Kamata, T., Kawai, Y., Takeuchi, K., Watanabe, K., Okamoto, S. & Ogawa, T., 1992 11, In: [Rinshō ketsueki] The Japanese journal of clinical hematology. 33, 11, p. 1679-1684 6 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

1991

The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress

Ikeda, Y., Handa, M., Kawano, K., Kamata, T., Murata, M., Araki, Y., Anbo, H., Kawai, Y., Watanabe, K., Itagaki, I., Sakai, K. & Ruggeri, Z. M., 1991 4, In: Journal of Clinical Investigation. 87, 4, p. 1234-1240 7 p.

研究成果: Article › 査読

Open Access

514 被引用数 (Scopus)

1990

Effects of anti-platelet agents on shear-induced platelet aggregation

Ikeda, Y., Handa, M., Kawano, K., Kamata, T., Anyasu, H., Araki, Y., kawaiY & Watanabe, K., 1990 6 1, In: [Rinsho ketsueki] The Japanese journal of clinical hematology. 31, 6, p. 787-792 6 p.

研究成果: Article › 査読

Enhancing effect by heparin on shear-induced platelet aggregation

Kawano, K., Ikeda, Y., Handa, M., Kamata, T., Anbo, H., Araki, Y., Kawai, Y., Watanabe, K., Itagaki, I., Kawakami, K., Fukuyama, M. & Sakai, K., 1990 1 1, In: Seminars in Thrombosis and Hemostasis. 16, SUPPL., p. 60-65 6 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

1989

Role of membrane glycoproteins in the interaction of blood platelets with the vessel wall--the study on platelet adhesion to in vitro cultured subendothelial matrix.

Kawai, Y., Handa, M., Nagai, H., Kamata, T., Anbo, H., Kawano, K., Araki, Y., Yamamoto, M., Ikeda, Y. & Watanabe, K., 1989 12, In: Acta Haematologica Japonica. 52, 8, p. 1312-1321 10 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

鎌田 徹治

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鎌田徹治