• 660 引用
  • 13 h指数
20042019

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 660 引用
  • 13 h指数
  • 23 Article
  • 1 Review article
2019

Induced Pluripotent Stem Cells Reprogrammed with Three Inhibitors Show Accelerated Differentiation Potentials with High Levels of 2-Cell Stage Marker Expression

Nishihara, K., Shiga, T., Nakamura, E., Akiyama, T., Sasaki, T., Suzuki, S., Ko, M., Tada, N., Okano, H. & Akamatsu, W., 2019 2 12, : : Stem Cell Reports. 12, 2, p. 305-318 14 p.

研究成果: Article

3 引用 (Scopus)

Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors

Hiratsuka, K., Monkawa, T., Akiyama, T., Nakatake, Y., Oda, M., Goparaju, S. K., Kimura, H., Chikazawa-Nohtomi, N., Sato, S., Ishiguro, K., Yamaguchi, S., Suzuki, S., Morizane, R., Ko, S., Itoh, H. & Ko, M. S. H., 2019 12 1, : : Scientific Reports. 9, 1, 913.

研究成果: Article

5 引用 (Scopus)
2018

Efficient differentiation of human pluripotent stem cells into skeletal muscle cells by combining RNA-based MYOD1-expression and POU5F1-silencing

Akiyama, T., Sato, S., Chikazawa-Nohtomi, N., Soma, A., Kimura, H., Wakabayashi, S., Ko, S. & Ko, M., 2018 12 1, : : Scientific Reports. 8, 1, 1189.

研究成果: Article

3 引用 (Scopus)

Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors 10 Technology 1004 Medical Biotechnology

Ida, H., Akiyama, T., Ishiguro, K., Goparaju, S. K., Nakatake, Y., Chikazawa-Nohtomi, N., Sato, S., Kimura, H., Yokoyama, Y., Nagino, M., Ko, M. S. H. & Ko, S. B. H., 2018 10 25, : : Stem Cell Research and Therapy. 9, 1, 277.

研究成果: Article

3 引用 (Scopus)
2017

Epigenetic Manipulation Facilitates the Generation of Skeletal Muscle Cells from Pluripotent Stem Cells

Akiyama, T., Wakabayashi, S., Soma, A., Sato, S., Nakatake, Y., Oda, M., Murakami, M., Sakota, M., Chikazawa-Nohtomi, N., Ko, S. & Ko, M., 2017, : : Stem Cells International. 2017, 7215010.

研究成果: Review article

2 引用 (Scopus)

Expression analysis of the endogenous Zscan4 locus and its coding proteins in mouse ES cells and preimplantation embryos

Ishiguro, K. I., Nakatake, Y., Chikazawa-Nohtomi, N., Kimura, H., Akiyama, T., Oda, M., Ko, S. B. H. & Ko, M. S. H., 2017 2 1, : : In Vitro Cellular and Developmental Biology - Animal. 53, 2, p. 179-190 12 p.

研究成果: Article

1 引用 (Scopus)

Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells

Hirayama, M., Ko, S., Kawakita, T., Akiyama, T., Goparaju, S. K., Soma, A., Nakatake, Y., Sakota, M., Chikazawa-Nohtomi, N., Shimmura, S., Tsubota, K. & Ko, M., 2017 12 1, : : npj Aging and Mechanisms of Disease. 3, 1, 1.

研究成果: Article

9 引用 (Scopus)

Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factors

Goparaju, S. K., Kohda, K., Ibata, K., Soma, A., Nakatake, Y., Akiyama, T., Wakabayashi, S., Matsushita, M., Sakota, M., Kimura, H., Yuzaki, M., Ko, S. & Ko, M., 2017 2 13, : : Scientific Reports. 7, 42367.

研究成果: Article

25 引用 (Scopus)

Zscan4 is expressed specifically during late meiotic prophase in both spermatogenesis and oogenesis

Ishiguro, K. I., Monti, M., Akiyama, T., Kimura, H., Chikazawa-Nohtomi, N., Sakota, M., Sato, S., Redi, C. A., Ko, S. B. H. & Ko, M. S. H., 2017 2 1, : : In Vitro Cellular and Developmental Biology - Animal. 53, 2, p. 167-178 12 p.

研究成果: Article

5 引用 (Scopus)
2016

Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells

Akiyama, T., Wakabayashi, S., Soma, A., Sato, S., Nakatake, Y., Oda, M., Murakami, M., Sakota, M., Chikazawa-Nohtomi, N., Ko, S. & Ko, M., 2016 10 15, : : Development (Cambridge). 143, 20, p. 3674-3685 12 p.

研究成果: Article

19 引用 (Scopus)
2015

Maternal TET3 is dispensable for embryonic development but is required for neonatal growth

Tsukada, Y. I., Akiyama, T. & Nakayama, K. I., 2015 10 28, : : Scientific reports. 5, 15876.

研究成果: Article

公開
20 引用 (Scopus)

Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cells

Akiyama, T., Xin, L., Oda, M., Sharov, A. A., Amano, M., Piao, Y., Cadet, J. S., Dudekula, D. B., Qian, Y., Wang, W., Ko, S. & Ko, M., 2015 5 6, : : DNA Research. 22, 5, p. 307-318 12 p.

研究成果: Article

33 引用 (Scopus)
2014

Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells

Yukawa, M., Akiyama, T., Franke, V., Mise, N., Isagawa, T., Suzuki, Y., Suzuki, M. G., Vlahovicek, K., Abe, K., Aburatani, H. & Aoki, F., 2014 3 21, : : PloS one. 9, 3, e92689.

研究成果: Article

公開
13 引用 (Scopus)
2013

Zscan4 restores the developmental potency of embryonic stem cells

Amano, T., Hirata, T., Falco, G., Monti, M., Sharova, L. V., Amano, M., Sheer, S., Hoang, H. G., Piao, Y., Stagg, C. A., Yamamizu, K., Akiyama, T. & Ko, M. S. H., 2013 6 6, : : Nature communications. 4, 1966.

研究成果: Article

公開
59 引用 (Scopus)
2012

The expression and nuclear deposition of histone H3.1 in murine oocytes and preimplantation embryos

Kawamura, M., Akiyama, T., Tsukamoto, S., Suzuki, M. G. & Aoki, F., 2012 11 19, : : Journal of Reproduction and Development. 58, 5, p. 557-562 6 p.

研究成果: Article

公開
6 引用 (Scopus)
2011

Dramatic replacement of histone variants during genome remodeling in nuclear-transferred embryos

Nashun, B., Akiyama, T., Suzuki, M. G. & Aoki, F., 2011 1 1, : : Epigenetics. 6, 12, p. 1489-1497 9 p.

研究成果: Article

公開
27 引用 (Scopus)

Dynamic replacement of histone H3 variants reprograms epigenetic marks in early mouse embryos

Akiyama, T., Suzuki, O., Matsuda, J. & Aoki, F., 2011 10 1, : : PLoS Genetics. 7, 10, e1002279.

研究成果: Article

公開
89 引用 (Scopus)
2010

Changes in the nuclear deposition of histone H2A variants during pre-implantation development in mice

Nashun, B., Yukawa, M., Liu, H., Akiyama, T. & Aoki, F., 2010 11 15, : : Development. 137, 22, p. 3785-3794 10 p.

研究成果: Article

公開
70 引用 (Scopus)
2008

Changes in H3K79 methylation during preimplantation development in mice

Ooga, M., Inoue, A., Kageyama, S. I., Akiyama, T., Nagata, M. & Aoki, F., 2008 3 1, : : Biology of reproduction. 78, 3, p. 413-424 12 p.

研究成果: Article

公開
63 引用 (Scopus)

Changes in histone modification upon activation of dormant mouse blastocysts

Matsuhashi, T., Akiyama, T., Aoki, F. & Sakai, S., 2007 12 1, : : Animal Science Journal. 78, 6, p. 575-586 12 p.

研究成果: Article

The perivitelline space-forming capacity of mouse oocytes is associated with meiotic competence

Inoue, A., Akiyama, T., Nagata, M. & Aoki, F., 2007 10 1, : : Journal of Reproduction and Development. 53, 5, p. 1043-1052 10 p.

研究成果: Article

公開
21 引用 (Scopus)
2006
公開
121 引用 (Scopus)
2004

Regulation of histone acetylation during meiotic maturation in mouse oocytes

Akiyama, T., Kim, J. M., Nagata, M. & Aoki, F., 2004 10 1, : : Molecular reproduction and development. 69, 2, p. 222-227 6 p.

研究成果: Article

63 引用 (Scopus)