• 1765 引用
  • 22 h指数
19982020

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

フィルター
Article
2020

Annexin A1 accounts for an anti-inflammatory binding target of sesamin metabolites

Kabe, Y., Takemoto, D., Kanai, A., Hirai, M., Ono, Y., Akazawa, S., Horikawa, M., Kitagawa, Y., Handa, H., Rogi, T., Shibata, H. & Suematsu, M., 2020 12 1, : : npj Science of Food. 4, 1, 4.

研究成果: Article

公開

Comparative Glycomic Analysis of Exosome Subpopulations Derived from Pancreatic Cancer Cell Lines

Matsuda, A., Kuno, A., Yoshida, M., Wagatsuma, T., Sato, T., Miyagishi, M., Zhao, J., Suematsu, M., Kabe, Y. & Narimatsu, H., 2020 6 5, : : Journal of Proteome Research. 19, 6, p. 2516-2524 9 p.

研究成果: Article

2019

Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo

Kobayashi, H., Morikawa, T., Okinaga, A., Hamano, F., Hashidate-Yoshida, T., Watanuki, S., Hishikawa, D., Shindou, H., Arai, F., Kabe, Y., Suematsu, M., Shimizu, T. & Takubo, K., 2019 7 2, : : Cell Reports. 28, 1, p. 145-158.e9

研究成果: Article

公開
4 引用 (Scopus)

Identification of a binding protein for sesamin and characterization of its roles in plant growth

Tera, M., Koyama, T., Murata, J., Furukawa, A., Mori, S., Azuma, T., Watanabe, T., Hori, K., Okazawa, A., Kabe, Y., Suematsu, M., Satake, H., Ono, E. & Horikawa, M., 2019 12 1, : : Scientific reports. 9, 1, 8631.

研究成果: Article

公開
4 引用 (Scopus)

Xanthine oxidase inhibitor ameliorates postischemic renal injury in mice by promoting resynthesis of adenine nucleotides

Fujii, K., Kubo, A., Miyashita, K., Sato, M., Hagiwara, A., Inoue, H., Ryuzaki, M., Tamaki, M., Hishiki, T., Hayakawa, N., Kabe, Y., Itoh, H. & Suematsu, M., 2019 11 14, : : JCI Insight. 4, 22, e124816.

研究成果: Article

公開
1 引用 (Scopus)
2018

Baicalein Targets GTPase-Mediated Autophagy to Eliminate Liver Tumor–Initiating Stem Cell–Like Cells Resistant to mTORC1 Inhibition

Wu, R., Murali, R., Kabe, Y., French, S. W., Chiang, Y. M., Liu, S., Sher, L., Wang, C. C., Louie, S. & Tsukamoto, H., 2018 11 1, : : Hepatology. 68, 5, p. 1726-1740 15 p.

研究成果: Article

16 引用 (Scopus)

Development of a highly sensitive device for counting the number of disease-specific exosomes in human sera

Kabe, Y., Suematsu, M., Sakamoto, S., Hirai, M., Koike, I., Hishiki, T., Matsuda, A., Hasegawa, Y., Tsujita, K., Ono, M., Minegishi, N., Hozawa, A., Murakami, Y., Kubo, M., Itonaga, M. & Handa, H., 2018 10, : : Clinical Chemistry. 64, 10, p. 1463-1473 11 p.

研究成果: Article

11 引用 (Scopus)

Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival

Shiota, M., Naya, M., Yamamoto, T., Hishiki, T., Tani, T., Takahashi, H., Kubo, A., Koike, D., Itoh, M., Ohmura, M., Kabe, Y., Sugiura, Y., Hiraoka, N., Morikawa, T., Takubo, K., Suina, K., Nagashima, H., Sampetrean, O., Nagano, O., Saya, H. および3人, Yamazoe, S., Watanabe, H. & Suematsu, M., 2018 12 1, : : Nature Communications. 9, 1, 1561.

研究成果: Article

26 引用 (Scopus)
2017

Disorganized Steroidogenesis in Adrenocortical Carcinoma, a Case Study

Uchida, T., Nishimoto, K., Fukumura, Y., Asahina, M., Goto, H., Kawano, Y., Shimizu, F., Tsujimura, A., Seki, T., Mukai, K., Kabe, Y., Suematsu, M., Gomez-Sanchez, C. E., Yao, T., Horie, S. & Watada, H., 2017 3 1, : : Endocrine pathology. 28, 1, p. 27-35 9 p.

研究成果: Article

2 引用 (Scopus)
1 引用 (Scopus)

Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1

Pati, M. L., Groza, D., Riganti, C., Kopecka, J., Niso, M., Berardi, F., Hager, S., Heffeter, P., Hirai, M., Tsugawa, H., Kabe, Y., Suematsu, M. & Abate, C., 2017 3 1, : : Pharmacological Research. 117, p. 67-74 8 p.

研究成果: Article

21 引用 (Scopus)

Somatic KCNJ5 mutation occurring early in adrenal development may cause a novel form of juvenile primary aldosteronism

Tamura, A., Nishimoto, K., Seki, T., Matsuzawa, Y., Saito, J., Omura, M., Gomez-Sanchez, C. E., Makita, K., Matsui, S., Moriya, N., Inoue, A., Nagata, M., Sasano, H., Nakamura, Y., Yamazaki, Y., Kabe, Y., Mukai, K., Kosaka, T., Oya, M., Suematsu, S. および1人, Nishikawa, T., 2017 2 5, : : Molecular and Cellular Endocrinology. 441, p. 134-139 6 p.

研究成果: Article

12 引用 (Scopus)

Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6

Lai, K. K. Y., Kweon, S. M., Chi, F., Hwang, E., Kabe, Y., Higashiyama, R., Qin, L., Yan, R., Wu, R. P., Lai, K., Fujii, N., French, S., Xu, J., Wang, J. Y., Murali, R., Mishra, L., Lee, J. S., Ntambi, J. M. & Tsukamoto, H., 2017 5 1, : : Gastroenterology. 152, 6, p. 1477-1491 15 p.

研究成果: Article

37 引用 (Scopus)
2016

Alteration of matrix metalloproteinase-3 O-glycan structure as a biomarker for disease activity of rheumatoid arthritis

Takeshita, M., Kuno, A., Suzuki, K., Matsuda, A., Shimazaki, H., Nakagawa, T., Otomo, Y., Kabe, Y., Suematsu, M., Narimatsu, H. & Takeuchi, T., 2016 5 21, : : Arthritis Research and Therapy. 18, 1, 112.

研究成果: Article

9 引用 (Scopus)

Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

Kabe, Y., Nakane, T., Koike, I., Yamamoto, T., Sugiura, Y., Harada, E., Sugase, K., Shimamura, T., Ohmura, M., Muraoka, K., Yamamoto, A., Uchida, T., Iwata, S., Yamaguchi, Y., Krayukhina, E., Noda, M., Handa, H., Ishimori, K., Uchiyama, S., Kobayashi, T. および1人, Suematsu, M., 2016 3 18, : : Nature Communications. 7, 11030.

研究成果: Article

70 引用 (Scopus)

Human Adrenocortical Remodeling Leading to Aldosterone-Producing Cell Cluster Generation

Nishimoto, K., Seki, T., Hayashi, Y., Mikami, S., Al-Eyd, G., Nakagawa, K., Morita, S., Kosaka, T., Oya, M., Mitani, F., Suematsu, M., Kabe, Y. & Mukai, K., 2016, : : International Journal of Endocrinology. 2016, 7834356.

研究成果: Article

22 引用 (Scopus)
2015
14 引用 (Scopus)

LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C

Masuda, K., Chiyoda, T., Sugiyama, N., Segura-Cabrera, A., Kabe, Y., Ueki, A., Banno, K., Suematsu, M., Aoki, D., Ishihama, Y., Saya, H. & Kuninaka, S., 2015 2 27, : : PloS one. 10, 2, e0118662.

研究成果: Article

8 引用 (Scopus)
2014

Microscopic imaging mass spectrometry assisted by on-tissue chemical derivatization for visualizing multiple amino acids in human colon cancer xenografts

Toue, S., Sugiura, Y., Kubo, A., Ohmura, M., Karakawa, S., Mizukoshi, T., Yoneda, J., Miyano, H., Noguchi, Y., Kobayashi, T., Kabe, Y. & Suematsu, M., 2014 1 1, : : Proteomics. 14, 7-8, p. 810-819 10 p.

研究成果: Article

30 引用 (Scopus)
2013

Vesnarinone suppresses TNFa mRNA expression by inhibiting valosin-containing protein

Hotta, K., Nashimoto, A., Yasumura, E., Suzuki, M., Azuma, M., Iizumi, Y., Shima, D., Nabeshima, R., Hiramoto, M., Okada, A., Sakata-Sogawa, K., Tokunaga, M., Ito, T., Ando, H., Sakamoto, S., Kabe, Y., Aizawa, S., Imai, T., Yamaguchi, Y., Watanabe, H. および1人, Handa, H., 2013 5, : : Molecular Pharmacology. 83, 5, p. 930-938 9 p.

研究成果: Article

6 引用 (Scopus)

Vitamin K2 covalently binds to bak and induces bak-mediated apoptosiss

Karasawa, S., Azuma, M., Kasama, T., Sakamoto, S., Kabe, Y., Imai, T., Yamaguchi, Y., Miyazawa, K. & Handa, H., 2013 3 1, : : Molecular Pharmacology. 83, 3, p. 613-620 8 p.

研究成果: Article

24 引用 (Scopus)
2012

HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice

Nishiyama, Y., Goda, N., Kanai, M., Niwa, D., Osanai, K., Yamamoto, Y., Senoo-Matsuda, N., Johnson, R. S., Miura, S., Kabe, Y. & Suematsu, M., 2012 2, : : Journal of Hepatology. 56, 2, p. 441-447 7 p.

研究成果: Article

56 引用 (Scopus)

Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway

Morikawa, T., Kajimura, M., Nakamura, T., Hishiki, T., Nakanishi, T., Yukutake, Y., Nagahata, Y., Ishikawa, M., Hattori, K., Takenouchi, T., Takahashi, T., Ishii, I., Matsubara, K., Kabe, Y., Uchiyama, S., Nagata, E., Gadalla, M. M., Snyder, S. H. & Suematsu, M., 2012 1 24, : : Proceedings of the National Academy of Sciences of the United States of America. 109, 4, p. 1293-1298 6 p.

研究成果: Article

150 引用 (Scopus)
13 引用 (Scopus)
2010

Identification of dynamin-2-mediated endocytosis as a new target of osteoporosis drugs, bisphosphonates

Masaike, Y., Takagi, T., Hirota, M., Yamada, J., Ishihara, S., Yung, T. M. C., Inoue, T., Sawa, C., Sagara, H., Sakamoto, S., Kabe, Y., Takahashi, Y., Yamaguchi, Y. & Handa, H., 2010 2 1, : : Molecular Pharmacology. 77, 2, p. 262-269 8 p.

研究成果: Article

16 引用 (Scopus)
2009

Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus

Kuramori, C., Azuma, M., Kume, K., Kaneko, Y., Inoue, A., Yamaguchi, Y., Kabe, Y., Hosoya, T., Kizaki, M., Suematsu, M. & Handa, H., 2009 2 6, : : Biochemical and Biophysical Research Communications. 379, 2, p. 519-525 7 p.

研究成果: Article

35 引用 (Scopus)

Development and application of high-performance affinity beads: Toward chemical biology and drug discovery

Sakamoto, S., Kabe, Y., Hatakeyama, M., Yamaguchi, Y. & Handa, H., 2009 3 5, : : Chemical Record. 9, 1, p. 66-85 20 p.

研究成果: Article

51 引用 (Scopus)

Inhibitory effect of N,N-didesmethylgrossularine-1 on inflammatory cytokine production in lipopolysaccharide-stimulated RAW 264.7 cells

Oda, T., Lee, J. S., Sato, Y., Kabe, Y., Sakamoto, S., Handa, H., Mangindaan, R. E. P. & Namikoshi, M., 2009 12 1, : : Marine Drugs. 7, 4, p. 589-599 11 p.

研究成果: Article

14 引用 (Scopus)

Mono-(2-ethylhexyl) phthalate targets glycogen debranching enzyme and affects glycogen metabolism in rat testis

Kuramori, C., Hase, Y., Hoshikawa, K., Watanabe, K., Nishi, T., Hishiki, T., Soga, T., Nashimoto, A., Kabe, Y., Yamaguchi, Y., Watanabe, H., Kataoka, K., Suematsu, M. & Handa, H., 2009 5 13, : : Toxicological Sciences. 109, 1, p. 143-151 9 p.

研究成果: Article

11 引用 (Scopus)

Preparation of conophylline affinity nano-beads and identification of a target protein

Suzuki, E., Ogura, H., Kato, K., Takei, I., Kabe, Y., Handa, H. & Umezawa, K., 2009 9 1, : : Bioorganic and Medicinal Chemistry. 17, 17, p. 6188-6195 8 p.

研究成果: Article

8 引用 (Scopus)
55 引用 (Scopus)
2008

Adenine nucleotide translocator transports haem precursors into mitochondria

Azuma, M., Kabe, Y., Kuramori, C., Kondo, M., Yamaguchi, Y. & Handa, H., 2008 8 27, : : PloS one. 3, 8, e3070.

研究成果: Article

41 引用 (Scopus)

A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity

Ando, K., Hirao, S., Kabe, Y., Ogura, Y., Sato, I., Yamaguchi, Y., Wada, T. & Handa, H., 2008 8, : : Nucleic acids research. 36, 13, p. 4327-4336 10 p.

研究成果: Article

95 引用 (Scopus)
15 引用 (Scopus)

Atrazine binds to F1F0-ATP synthase and inhibits mitochondrial function in sperm

Hase, Y., Tatsuno, M., Nishi, T., Kataoka, K., Kabe, Y., Yamaguchi, Y., Ozawa, N., Natori, M., Handa, H. & Watanabe, H., 2008 2 1, : : Biochemical and Biophysical Research Communications. 366, 1, p. 66-72 7 p.

研究成果: Article

38 引用 (Scopus)

Development of a chemical screening system using aqueorin-fused protein

Suzuki, M., Furukawa, S., Kuramori, C., Sawa, C., Kabe, Y., Nakamura, M., Sawada, J. I., Yamaguchi, Y., Sakamoto, S., Inouye, S. & Handa, H., 2008 4 11, : : Biochemical and Biophysical Research Communications. 368, 3, p. 600-605 6 p.

研究成果: Article

2 引用 (Scopus)
2007

hnRNP-U enhances the expression of specific genes by stabilizing mRNA

Yugami, M., Kabe, Y., Yamaguchi, Y., Wada, T. & Handa, H., 2007 1 9, : : FEBS Letters. 581, 1, p. 1-7 7 p.

研究成果: Article

37 引用 (Scopus)

Polymer particles as the carrier for affinity purification

Hatakeyama, M., Nishio, K., Nakamura, M., Sakamoto, S., Kabe, Y., Wada, T. & Handa, H., 2007 1 1, : : Kobunshi Ronbunshu. 64, 1, p. 9-20 12 p.

研究成果: Article

3 引用 (Scopus)

The Enteropathogenic E. coli Effector EspB Facilitates Microvillus Effacing and Antiphagocytosis by Inhibiting Myosin Function

Iizumi, Y., Sagara, H., Kabe, Y., Azuma, M., Kume, K., Ogawa, M., Nagai, T., Gillespie, P. G., Sasakawa, C. & Handa, H., 2007 12 13, : : Cell Host and Microbe. 2, 6, p. 383-392 10 p.

研究成果: Article

70 引用 (Scopus)
2006

Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier

Kabe, Y., Ohmori, M., Shinouchi, K., Tsuboi, Y., Hirao, S., Azuma, M., Watanabe, H., Okura, I. & Handa, H., 2006 10 20, : : Journal of Biological Chemistry. 281, 42, p. 31729-31735 7 p.

研究成果: Article

45 引用 (Scopus)

TFII-I down-regulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor α

Ogura, Y., Azuma, M., Tsuboi, Y., Kabe, Y., Yamaguchi, Y., Wada, T., Watanabe, H. & Handa, H., 2006 4 1, : : Genes to Cells. 11, 4, p. 373-381 9 p.

研究成果: Article

16 引用 (Scopus)
2005

GABP, HCF-1 and YY1 are involved in Rb gene expression during myogenesis

Deléhouzée, S., Yoshikawa, T., Sawa, C., Sawada, J. I., Ito, T., Omori, M., Wada, T., Yamaguchi, Y., Kabe, Y. & Handa, H., 2005 7 1, : : Genes to Cells. 10, 7, p. 717-731 15 p.

研究成果: Article

42 引用 (Scopus)

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

Kabe, Y., Yamada, J., Uga, H., Yamaguchi, Y., Wada, T. & Handa, H., 2005 1 1, : : Molecular and cellular biology. 25, 1, p. 512-522 11 p.

研究成果: Article

68 引用 (Scopus)
2004

Design and synthesis of a solid-supported FR225659 derivative for its receptor screening

Zenkoh, T., Hatori, H., Tanaka, H., Hasegawa, M., Hatakeyama, M., Kabe, Y., Setoi, H., Kawaguchi, H., Handa, H. & Takahashi, T., 2004 7 8, : : Organic Letters. 6, 14, p. 2477-2480 4 p.

研究成果: Article

14 引用 (Scopus)

Screening of drug target receptor by using nanotechnology

Hatakeyama, M., Kabe, Y. & Handa, H., 2004, : : Drug Delivery System. 19, 2, p. 127-132 6 p.

研究成果: Article

1999

Identification of the core domain and the secondary structure of the transcriptional coactivator MBF-1

Ozaki, J., Takemaru, K. I., Ikegami, T., Mishima, M., Ueda, H., Hirose, S., Kabe, Y., Handa, H. & Shirakawa, M., 1999 9 6, : : Genes to Cells. 4, 7, p. 415-424 10 p.

研究成果: Article

15 引用 (Scopus)

Resonance assignments, secondary structure and 15N relaxation data of the human transcriptional coactivator hMBF1 (57-148)

Mishima, M., Ozaki, J., Ikegami, T., Kabe, Y., Goto, M., Ueda, H., Hirose, S., Handa, H. & Shirakawa, M., 1999 10 18, : : Journal of Biomolecular NMR. 14, 4, p. 373-376 4 p.

研究成果: Article

9 引用 (Scopus)

The role of human MBF1 as a transcriptional coactivator

Kabe, Y., Goto, M., Shima, D., Imai, T., Wada, T., Morohashi, K. I., Shirakawa, M., Hirose, S. & Handa, H., 1999 11 26, : : Journal of Biological Chemistry. 274, 48, p. 34196-34202 7 p.

研究成果: Article

67 引用 (Scopus)
1998

(+)-Rhododendrol and epi-rhododendrin suppress the no production by activated macrophages in vivo

Fushiya, S., Kabe, Y., Ikegaya, Y. & Takano, F., 1998 11 2, : : Planta Medica. 64, 7, p. 598-602 5 p.

研究成果: Article

20 引用 (Scopus)