検索結果
2023
Yasukawa, T. ,
Sasaki, M. ,
Motomura, K. ,
Yuki, K. ,
Kurihara, T. ,
Tomita, Y. ,
Mori, K. ,
Ozawa, N. ,
Ozawa, Y. ,
Yamagishi, K. ,
Hanyuda, A. ,
Sawada, N. ,
Tsubota, K. ,
Tsugane, S. &
Iso, H. ,
2023 1月 1 ,
In: Translational Vision Science and Technology. 12 ,
1 , 3.
研究成果: Article › 査読
Saturated fatty acids
100%
Monounsaturated fatty acids
75%
Fatty acids
70%
Polyunsaturated fatty acids
68%
Macular Degeneration
60%
Lee, D. ,
Tomita, Y. ,
Negishi, K. &
Kurihara, T. ,
2023 7月 ,
In: Neural Regeneration Research. 18 ,
7 ,
p. 1495-1496 2 p. 研究成果: Article › 査読
Lee, D. ,
Nakai, A. ,
Miwa, Y. ,
Negishi, K. ,
Tomita, Y. &
Kurihara, T. ,
2023 1月 ,
In: PeerJ. 11 , e14611.
研究成果: Article › 査読
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid
100%
macular degeneration
73%
Choroidal Neovascularization
61%
angiogenesis
60%
Growth Factor
58%
2022
Wang, Z. ,
Yemanyi, F. ,
Blomfield, A. K. ,
Bora, K. ,
Huang, S. ,
Liu, C. H. ,
Britton, W. R. ,
Cho, S. S. ,
Tomita, Y. ,
Fu, Z. ,
Ma, J. X. ,
Li, W. H. &
Chen, J. ,
2022 ,
In: eLife. 11 , e73105.
研究成果: Article › 査読
Pathologic Neovascularization
100%
Amino Acid Transport Systems
96%
Developmental
86%
Retinal Vessels
83%
Retinal
81%
Gong, Y. ,
Tomita, Y. ,
Edin, M. L. ,
Ren, A. ,
Ko, M. ,
Yang, J. ,
Bull, E. ,
Zeldin, D. C. ,
Hellström, A. ,
Fu, Z. &
Smith, L. E. H. ,
2022 9月 ,
In: Metabolism: clinical and experimental. 134 , 155266.
研究成果: Article › 査読
arachidonate epoxygenase
100%
Choroidal Neovascularization
74%
Electron Transport Complex IV
69%
Cytochrome P-450 Enzyme System
57%
Unsaturated Fatty Acids
50%
Bora, K. ,
Wang, Z. ,
Yemanyi, F. ,
Maurya, M. ,
Blomfield, A. K. ,
Tomita, Y. &
Chen, J. ,
2022 6月 ,
In: Journal of Visualized Experiments. 2022 ,
184 , e64076.
研究成果: Article › 査読
Endothelial cells
100%
Blood-Retinal Barrier
98%
Transcytosis
90%
Assays
78%
Retinal
77%
Lee, D. ,
Tomita, Y. ,
Miwa, Y. ,
Shinojima, A. ,
Ban, N. ,
Yamaguchi, S. ,
Nishioka, K. ,
Negishi, K. ,
Yoshino, J. &
Kurihara, T. ,
2022 10月 ,
In: International journal of molecular sciences. 23 ,
19 , 11228.
研究成果: Article › 査読
Oxidative stress
100%
Nicotinamide Mononucleotide
99%
nicotinamide
91%
Cell death
85%
ischemia
84%
Lee, D. ,
Tomita, Y. ,
Miwa, Y. ,
Jeong, H. ,
Shinojima, A. ,
Ban, N. ,
Yamaguchi, S. ,
Nishioka, K. ,
Negishi, K. ,
Yoshino, J. &
Kurihara, T. ,
2022 12月 ,
In: International journal of molecular sciences. 23 ,
23 , 14711.
研究成果: Article › 査読
Nicotinamide Mononucleotide
100%
nicotinamide
92%
occlusion
75%
Retinal
66%
arteries
65%
Ofuji, Y. ,
Katada, Y. ,
Tomita, Y. ,
Nagai, N. ,
Sonobe, H. ,
Watanabe, K. ,
Shinoda, H. ,
Ozawa, Y. ,
Negishi, K. ,
Tsubota, K. &
Kurihara, T. ,
2022 4月 ,
In: Life. 12 ,
4 , 542.
研究成果: Article › 査読
diabetic retinopathy
100%
Proliferative
80%
angiography
77%
progressions
67%
Diabetic Retinopathy
62%
Lee, D. ,
Nakai, A. ,
Miwa, Y. ,
Tomita, Y. ,
Kunimi, H. ,
Chen, J. ,
Ikeda, S. I. ,
Tsubota, K. ,
Negishi, K. &
Kurihara, T. ,
2022 9月 ,
In: FASEB Journal. 36 ,
9 , e22497.
研究成果: Article › 査読
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid
100%
Retinal Degeneration
61%
Retinal
56%
Wounds and Injuries
24%
Peroxisome Proliferator-Activated Receptors
13%
2021
Mori, T. ,
Kikuchi, T. ,
Koh, M. ,
Koda, Y. ,
Yamazaki, R. ,
Sakurai, M. ,
Tomita, Y. ,
Ozawa, Y. ,
Kohashi, S. ,
Abe, R. ,
Saburi, M. &
Kato, J. ,
2021 6月 ,
In: Bone Marrow Transplantation. 56 ,
6 ,
p. 1266-1271 6 p. 研究成果: Article › 査読
Cytomegalovirus Retinitis
100%
Hematopoietic Stem Cell Transplantation
74%
Cytomegalovirus
69%
Cytomegalovirus Infections
43%
Incidence
24%
Lee, D. ,
Tomita, Y. ,
Miwa, Y. ,
Jeong, H. ,
Mori, K. ,
Tsubota, K. &
Kurihara, T. ,
2021 3月 ,
In: Pharmaceuticals. 14 ,
3 , 223.
研究成果: Article › 査読
Fenofibrate
100%
Ocular
81%
Retinal
73%
Common Carotid Artery
71%
Ischemia
48%
Ozawa, H. ,
Usui, Y. ,
Takano, Y. ,
Horiuchi, N. ,
Kuribayashi, T. ,
Kurihara, T. ,
Smith, L. E. H. ,
Tsubota, K. &
Tomita, Y. ,
2021 6月 4 ,
In: Medicine (United States). 100 ,
22 ,
p. E26232 研究成果: Article › 査読
Iris
100%
Esophageal Neoplasms
92%
Fine Needle Biopsy
92%
Neoplasm Metastasis
56%
Eye
42%
Tomita, Y. ,
Qiu, C. ,
Bull, E. ,
Allen, W. ,
Kotoda, Y. ,
Talukdar, S. ,
Smith, L. E. H. &
Fu, Z. ,
2021 11月 ,
In: Experimental and Molecular Medicine. 53 ,
11 ,
p. 1748-1758 11 p. 研究成果: Article › 査読
Retinitis Pigmentosa
100%
Rod Like Crystal
76%
Neuroglia
72%
Retinal
70%
Vertebrate Photoreceptor Cells
61%
Wang, T. ,
Zhou, P. ,
Xie, X. ,
Tomita, Y. ,
Cho, S. ,
Tsirukis, D. ,
Lam, E. ,
Luo, H. R. &
Sun, Y. ,
2021 11月 ,
In: EBioMedicine. 73 , 103632.
研究成果: Article › 査読
Pathologic Neovascularization
100%
Choroidal Neovascularization
88%
Agonist
67%
Cytokines
44%
Cell Lineage
24%
Lee, D. ,
Tomita, Y. ,
Jeong, H. ,
Miwa, Y. ,
Tsubota, K. ,
Negishi, K. &
Kurihara, T. ,
2021 9月 1 ,
In: International journal of molecular sciences. 22 ,
17 , 9408.
研究成果: Article › 査読
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid
100%
ischemia
72%
occlusion
64%
Retinal
56%
arteries
55%
Lee, D. ,
Nakai, A. ,
Miwa, Y. ,
Tomita, Y. ,
Serizawa, N. ,
Katada, Y. ,
Hatanaka, Y. ,
Tsubota, K. ,
Negishi, K. &
Kurihara, T. ,
2021 ,
In: BioMed Research International. 2021 , 7727648.
研究成果: Article › 査読
Retinal Degeneration
100%
Retinal
93%
Common Carotid Artery
90%
Ischemia
61%
Ocular
59%
Fu, Z. ,
Qiu, C. ,
Cagnone, G. ,
Tomita, Y. ,
Huang, S. ,
Cakir, B. ,
Kotoda, Y. ,
Allen, W. ,
Bull, E. ,
Akula, J. D. ,
Joyal, J. S. ,
Hellström, A. ,
Talukdar, S. &
Smith, L. E. H. ,
2021 4月 23 ,
In: iScience. 24 ,
4 , 102376.
研究成果: Article › 査読
fibroblast growth factor 21
100%
Neuroglia
60%
Retinitis Pigmentosa
50%
Retinal Degeneration
33%
Neuroprotection
28%
Tomita, Y. ,
Lee, D. ,
Tsubota, K. ,
Negishi, K. &
Kurihara, T. ,
2021 10月 2 ,
In: Journal of Clinical Medicine. 10 ,
20 , 4666.
研究成果: Article › 査読
Diabetic Retinopathy
100%
Macular Edema
30%
Vascular Endothelial Growth Factor A
22%
PPAR alpha
22%
Light Coagulation
20%
Tomita, Y. ,
Cagnone, G. ,
Fu, Z. ,
Cakir, B. ,
Kotoda, Y. ,
Asakage, M. ,
Wakabayashi, Y. ,
Hellström, A. ,
Joyal, J. S. ,
Talukdar, S. ,
Smith, L. E. H. &
Usui, Y. ,
2021 1月 ,
In: Diabetologia. 64 ,
1 ,
p. 70-82 13 p. 研究成果: Article › 査読
Metabolomics
100%
Diabetic Retinopathy
94%
Creatine
93%
Vitreous Body
45%
Retinal Neovascularization
31%
2020
Tomita, Y. ,
Shao, Z. ,
Cakir, B. ,
Kotoda, Y. ,
Fu, Z. &
Smith, L. E. H. ,
2020 8月 ,
In: Journal of Visualized Experiments. 2020 ,
162 ,
p. 1-10 10 p. , e61677.
研究成果: Article › 査読
Endothelial cells
100%
Ocular
86%
Choroid
79%
Assays
78%
Retinal
77%
Tomita, Y. ,
Cakir, B. ,
Liu, C. H. ,
Fu, Z. ,
Huang, S. ,
Cho, S. S. ,
Britton, W. R. ,
Sun, Y. ,
Puder, M. ,
Hellström, A. ,
Talukdar, S. &
Smith, L. E. H. ,
2020 8月 1 ,
In: Angiogenesis. 23 ,
3 ,
p. 385-394 10 p. 研究成果: Article › 査読
Choroidal Neovascularization
100%
Nonesterified Fatty Acids
84%
Retinal Pigment
50%
Retinal Pigment Epithelium
42%
Agonist
35%
Cakir, B. ,
Hellström, W. ,
Tomita, Y. ,
Fu, Z. ,
Liegl, R. ,
Winberg, A. ,
Hansen-Pupp, I. ,
Ley, D. ,
Hellström, A. ,
Löfqvist, C. &
Smith, L. E. H. ,
2020 10月 2 ,
In: JCI Insight. 5 ,
19 , 140363.
研究成果: Article › 査読
Extremely Premature Infants
100%
Retinopathy of Prematurity
86%
Glucose
43%
Hyperglycemia
31%
Serum
31%
Tomita, Y. ,
Fu, Z. ,
Wang, Z. ,
Cakir, B. ,
Cho, S. S. ,
Britton, W. ,
Sun, Y. ,
Hellström, A. ,
Talukdar, S. &
Smith, L. E. H. ,
2020 2月 2 ,
In: International journal of molecular sciences. 21 ,
4 , 1188.
研究成果: Article › 査読
Intercellular Signaling Peptides and Proteins
100%
fibroblast growth factor 21
96%
Fibroblasts
95%
fibroblasts
83%
Retinal Vessels
77%
Tomita, Y. ,
Lee, D. ,
Miwa, Y. ,
Jiang, X. ,
Ohta, M. ,
Tsubota, K. &
Kurihara, T. ,
2020 9月 1 ,
In: International journal of molecular sciences. 21 ,
17 ,
p. 1-17 17 p. , 6243.
研究成果: Article › 査読
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid
100%
Retinal
56%
Diabetic Retinopathy
51%
mice
51%
blood
47%
Uchida, A. ,
Sasaki, M. ,
Motomura, K. ,
Yuki, K. ,
Kurihara, T. ,
Tomita, Y. ,
Ozawa, Y. ,
Yamagishi, K. ,
Kawasaki, R. ,
Hanyuda, A. ,
Sawada, N. ,
Tsubota, K. ,
Tsugane, S. &
Iso, H. ,
2020 12月 1 ,
In: Scientific reports. 10 ,
1 , 779.
研究成果: Article › 査読
Epiretinal Membrane
100%
Nerve Fibers
72%
Eye
45%
Optic Disk
32%
Population
28%
Wang, Z. ,
Liu, C. H. ,
Huang, S. ,
Fu, Z. ,
Tomita, Y. ,
Britton, W. R. ,
Cho, S. S. ,
Chen, C. T. ,
Sun, Y. ,
Ma, J. X. ,
He, X. &
Chen, J. ,
2020 8月 ,
In: Science Advances. 6 ,
35 , eaba7457.
研究成果: Article › 査読
Blood-Retinal Barrier
100%
Transcytosis
91%
Protein Domains
69%
Blood Vessels
40%
Caveolin 1
29%
2019
Tomita, Y. ,
Ozawa, N. ,
Miwa, Y. ,
Ishida, A. ,
Ohta, M. ,
Tsubota, K. &
Kurihara, T. ,
2019 12月 1 ,
In: International journal of molecular sciences. 20 ,
23 , 5878.
研究成果: Article › 査読
Peroxisome Proliferator-Activated Receptors
100%
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid
98%
Fenofibrate
76%
angiogenesis
73%
fibroblast growth factor 21
71%
2017
Sato, S. ,
Shinoda, H. ,
Nagai, N. ,
Suzuki, M. ,
Uchida, A. ,
Kurihara, T. ,
Kamoshita, M. ,
Tomita, Y. ,
Iyama, C. ,
Minami, S. ,
Yuki, K. ,
Tsubota, K. &
Ozawa, Y. ,
2017 ,
In: Medicine (United States). 96 ,
16 , e6459.
研究成果: Article › 査読
Endothelial Growth Factors
100%
Ranibizumab
91%
Macular Edema
78%
Visual Acuity
52%
Pharmaceutical Preparations
28%
2016
Suzuki, M. ,
Nagai, N. ,
Shinoda, H. ,
Uchida, A. ,
Kurihara, T. ,
Tomita, Y. ,
Kamoshita, M. ,
Iyama, C. ,
Tsubota, K. &
Ozawa, Y. ,
2016 6月 1 ,
In: American Journal of Ophthalmology. 166 ,
p. 52-59 8 p. 研究成果: Article › 査読
Ranibizumab
100%
Polyps
76%
Visual Acuity
28%
Optical Coherence Tomography
16%
Therapeutics
12%
Tomita, Y. ,
Nagai, N. ,
Suzuki, M. ,
Shinoda, H. ,
Uchida, A. ,
Mochimaru, H. ,
Izumi-Nagai, K. ,
Sasaki, M. ,
Tsubota, K. &
Ozawa, Y. ,
2016 ,
In: Optometry and Vision Science. 93 ,
1 ,
p. 70-76 7 p. 研究成果: Article › 査読
Macular Degeneration
100%
Visual Acuity
82%
Eye
42%
Optical Coherence Tomography
27%
Lenses
12%
2015
Nagai, N. ,
Izumi-Nagai, K. ,
Suzuki, M. ,
Shinoda, H. ,
Koto, T. ,
Uchida, A. ,
Mochimaru, H. ,
Tomita, Y. ,
Miyake, S. ,
Kobayashi, S. ,
Sasaki, M. ,
Tsubota, K. &
Ozawa, Y. ,
2015 4月 1 ,
In: Retina. 35 ,
4 ,
p. 820-826 7 p. 研究成果: Article › 査読
Macular Pigment
100%
oxidized low density lipoprotein
64%
Serum
29%
Confidence Intervals
16%
meso-zeaxanthin
13%
Tomita, Y. ,
Kurihara, T. ,
Uchida, A. ,
Nagai, N. ,
Shinoda, H. ,
Tsubota, K. &
Ozawa, Y. ,
2015 9月 2 ,
In: Scientific reports. 5 , 13256.
研究成果: Article › 査読
Scleral Buckling
100%
Ophthalmoscopy
88%
Retinal Detachment
37%
Eye
32%
Temazepam
20%
2014
Uchida, A. ,
Miwa, M. ,
Shinoda, H. ,
Koto, T. ,
Nagai, N. ,
Mochimaru, H. ,
Tomita, Y. ,
Sasaki, M. ,
Ikeda, K. ,
Tsubota, K. &
Ozawa, Y. ,
2014 ,
In: Journal of Ophthalmology. 2014 , 187929.
研究成果: Article › 査読
Retinopathy of Prematurity
100%
Maternal Age
85%
Gestational Age
69%
Lasers
51%
Confidence Intervals
47%