• 7862 引用
  • 49 h指数
1979 …2020

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 7862 引用
  • 49 h指数
  • 194 Article
  • 12 Review article
  • 2 Comment/debate
  • 1 Short survey
フィルター
Article
2020

Effect of TNIK upregulation on JQ1-resistant human colorectal cancer HCT116 cells

Takahashi, C., Kondo, S., Sadaoka, K., Ishizuka, S., Noguchi, K., Kato, Y. & Sugimoto, Y., 2020 9 10, : : Biochemical and Biophysical Research Communications. 530, 1, p. 230-234 5 p.

研究成果: Article

pH-dependent transport kinetics of the human organic anion-transporting polypeptide 1A2

Morita, T., Akiyoshi, T., Sato, R., Katayama, K., Yajima, K., Kataoka, H., Imaoka, A., Sugimoto, Y. & Ohtani, H., 2020 4, : : Drug Metabolism And Pharmacokinetics. 35, 2, p. 220-227 8 p.

研究成果: Article

Putative molecular determinants mediating sensitivity or resistance towards carnosic acid tumor cell responses

Mahmoud, N., Saeed, M. E. M., Sugimoto, Y., Klinger, A., Fleischer, E. & Efferth, T., 2020 10, : : Phytomedicine. 77, 153271.

研究成果: Article

1 引用 (Scopus)

SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells

Xu, S. W., Law, B. Y. K., Qu, S. L. Q., Hamdoun, S., Chen, J., Zhang, W., Guo, J. R., Wu, A. G., Mok, S. W. F., Zhang, D. W., Xia, C., Sugimoto, Y., Efferth, T., Liu, L. & Wong, V. K. W., 2020 3, : : Pharmacological Research. 153, 104660.

研究成果: Article

3 引用 (Scopus)
1 引用 (Scopus)
1 引用 (Scopus)
2019

Collateral sensitivity of drug-resistant ABCB5- and mutation-activated EGFR overexpressing cells towards resveratrol due to modulation of SIRT1 expression

Saeed, M. E. M., Rahama, M., Kuete, V., Dawood, M., Elbadawi, M., Sugimoto, Y. & Efferth, T., 2019 6, : : Phytomedicine. 59, 152890.

研究成果: Article

5 引用 (Scopus)

Cytotoxicity of 40 Egyptian plant extracts targeting mechanisms of drug-resistant cancer cells

Hegazy, M. E. F., Abdelfatah, S., Hamed, A. R., Mohamed, T. A., Elshamy, A. A., Saleh, I. A., Reda, E. H., Abdel-Azim, N. S., Shams, K. A., Sakr, M., Sugimoto, Y., Paré, P. W. & Efferth, T., 2019 6 1, : : Phytomedicine. 59, 152771.

研究成果: Article

3 引用 (Scopus)

Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells

Saeed, M. E. M., Boulos, J. C., Elhaboub, G., Rigano, D., Saab, A., Loizzo, M. R., Hassan, L. E. A., Sugimoto, Y., Piacente, S., Tundis, R., Yagi, S., Khalid, H. & Efferth, T., 2019 9 1, : : Phytomedicine. 62, 152945.

研究成果: Article

7 引用 (Scopus)
2 引用 (Scopus)

Regorafenib-Induced Hand-Foot Skin Reaction Is More Severe on the Feet Than on the Hands

Nonomiya, Y., Yokokawa, T., Kawakami, K., Kobayashi, K., Aoyama, T., Takiguchi, T., Sugisaki, T., Suzuki, K., Suenaga, M., Wakatsuki, T., Yamaguchi, K., Sugimoto, Y. & Hama, T., 2019 5 7, : : Oncology research. 27, 5, p. 551-556 6 p.

研究成果: Article

2 引用 (Scopus)
1 引用 (Scopus)
2018
12 引用 (Scopus)

Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cells

Fujiwara, C., Muramatsu, Y., Nishii, M., Tokunaka, K., Tahara, H., Ueno, M., Yamori, T., Sugimoto, Y. & Seimiya, H., 2018 12 1, : : Scientific reports. 8, 1, 14827.

研究成果: Article

2 引用 (Scopus)

Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation

Mahmoud, N., Saeed, M. E. M., Sugimoto, Y., Klauck, S. M., Greten, H. J. & Efferth, T., 2018 11 1, : : Oncotarget. 9, 87, p. 35762-35779 18 p.

研究成果: Article

公開
9 引用 (Scopus)

Cytotoxicity of sesquiterpene alkaloids from: Nuphar plants toward sensitive and drug-resistant cell lines

Fukaya, M., Nakamura, S., Hegazy, M. E. F., Sugimoto, Y., Hayashi, N., Nakashima, S., Yoshikawa, M., Efferth, T. & Matsuda, H., 2018, : : Food and Function. 9, 12, p. 6279-6286 8 p.

研究成果: Article

5 引用 (Scopus)
公開
3 引用 (Scopus)

IL-10 promoter transactivation by the viral K-RTA protein involves the host-cell transcription factors, specificity proteins 1 and 3

Miyazawa, M., Noguchi, K., Kujirai, M., Katayama, K., Yamagoe, S. & Sugimoto, Y., 2018 1 12, : : Journal of Biological Chemistry. 293, 2, p. 662-676 15 p.

研究成果: Article

3 引用 (Scopus)

Molecular determinants of sensitivity or resistance of cancer cells toward sanguinarine

Saeed, M. E. M., Mahmoud, N., Sugimoto, Y., Efferth, T. & Abdel-Aziz, H., 2018 2 26, : : Frontiers in Pharmacology. 9, FEB, 136.

研究成果: Article

10 引用 (Scopus)
5 引用 (Scopus)

Repurposing of bromocriptine for cancer therapy

Seo, E. J., Sugimoto, Y., Greten, H. J. & Efferth, T., 2018 10 8, : : Frontiers in Pharmacology. 9, OCT, 1030.

研究成果: Article

7 引用 (Scopus)
2017

APC mutations as a potential biomarker for sensitivity to tankyrase inhibitors in colorectal cancer

Tanaka, N., Mashima, T., Mizutani, A., Sato, A., Aoyama, A., Gong, B., Yoshida, H., Muramatsu, Y., Nakata, K., Matsuura, M., Katayama, R., Nagayama, S., Fujita, N., Sugimoto, Y. & Seimiya, H., 2017 4, : : Molecular cancer therapeutics. 16, 4, p. 752-762 11 p.

研究成果: Article

26 引用 (Scopus)

Functional effects of AKT3 on aurora kinase inhibitorinduced aneuploidy

Noguchi, K., Hongama, K., Hariki, S., Nonomiya, Y., Katayama, K. & Sugimoto, Y., 2017 2 3, : : Journal of Biological Chemistry. 292, 5, p. 1910-1924 15 p.

研究成果: Article

2 引用 (Scopus)

mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer

Mashima, T., Taneda, Y., Jang, M. K., Mizutani, A., Muramatsu, Y., Yoshida, H., Sato, A., Tanaka, N., Sugimoto, Y. & Seimiya, H., 2017, : : Oncotarget. 8, 29, p. 47902-47915 14 p.

研究成果: Article

13 引用 (Scopus)
2016

Effect of AKT3 expression on MYC- and caspase-8-dependent apoptosis caused by polo-like kinase inhibitors in HCT 116 cells

Nonomiya, Y., Noguchi, K., Tanaka, N., Kasagaki, T., Katayama, K. & Sugimoto, Y., 2016 12 1, : : Cancer science. 107, 12, p. 1877-1887 11 p.

研究成果: Article

5 引用 (Scopus)
8 引用 (Scopus)
2015
52 引用 (Scopus)

Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells

Saeed, M. E. M., Abdelgadir, H., Sugimoto, Y., Khalid, H. E. & Efferth, T., 2015 4 1, : : Journal of Ethnopharmacology. 174, p. 644-658 15 p.

研究成果: Article

21 引用 (Scopus)

Cytotoxicity of the sesquiterpene lactones neoambrosin and damsin from Ambrosia maritima against multidrug-resistant cancer cells

Saeed, M., Jacob, S., Sandjo, L. P., Sugimoto, Y., Khalid, H. E., Opatz, T., Thines, E. & Efferth, T., 2015, : : Frontiers in Pharmacology. 6, NOV, 267.

研究成果: Article

公開
16 引用 (Scopus)

Upregulation of cellular glutathione levels in human ABCB5- and murine Abcb5-transfected cells

Kondo, S., Hongama, K., Hanaya, K., Yoshida, R., Kawanobe, T., Katayama, K., Noguchi, K. & Sugimoto, Y., 2015 12 15, : : BMC Pharmacology and Toxicology. 16, 1, 37.

研究成果: Article

3 引用 (Scopus)
2014

Protein phosphatase complex PP5/PPP2R3C dephosphorylates P-glycoprotein/ABCB1 and down-regulates the expression and function

Katayama, K., Yamaguchi, M., Noguchi, K. & Sugimoto, Y., 2014 4 1, : : Cancer Letters. 345, 1, p. 124-131 8 p.

研究成果: Article

16 引用 (Scopus)

Resistance mechanisms of cancer cells to the novel vacuolar H+-ATPase inhibitor archazolid B

Hamm, R., Sugimoto, Y., Steinmetz, H. & Efferth, T., 2014 10, : : Investigational new drugs. 32, 5, p. 893-903 11 p., 32.

研究成果: Article

7 引用 (Scopus)
18 引用 (Scopus)
2013
17 引用 (Scopus)

FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin-proteasome pathway in cancer cells

Katayama, K., Noguchi, K. & Sugimoto, Y., 2013 6 1, : : Cancer science. 104, 6, p. 694-702 9 p.

研究成果: Article

22 引用 (Scopus)
2012

Expression of human ABCB5 confers resistance to taxanes and anthracyclines

Kawanobe, T., Kogure, S., Nakamura, S., Sato, M., Katayama, K., Mitsuhashi, J., Noguchi, K. & Sugimoto, Y., 2012 2 24, : : Biochemical and Biophysical Research Communications. 418, 4, p. 736-741 6 p.

研究成果: Article

36 引用 (Scopus)
2011

DNA ligand designed to antagonize EBNA1 represses Epstein-Barr virus-induced immortalization

Yasuda, A., Noguchi, K., Minoshima, M., Kashiwazaki, G., Kanda, T., Katayama, K., Mitsuhashi, J., Bando, T., Sugiyama, H. & Sugimoto, Y., 2011 12 1, : : Cancer science. 102, 12, p. 2221-2230 10 p.

研究成果: Article

22 引用 (Scopus)

Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRP/ABCG2-mediated drug resistance in vitro and in vivo

Yamazaki, R., Nishiyama, Y., Furuta, T., Hatano, H., Igarashi, Y., Asakawa, N., Kodaira, H., Takahashi, H., Aiyama, R., Matsuzaki, T., Yagi, N. & Sugimoto, Y., 2011 7 1, : : Molecular cancer therapeutics. 10, 7, p. 1252-1263 12 p.

研究成果: Article

34 引用 (Scopus)

Novel regulatory role for Kaposi's sarcoma-associated herpesvirus-encoded vFLIP in chemosensitization to bleomycin

Masuda, Y., Noguchi, K., Segawa, H., Tanaka, N., Katayama, K., Mitsuhashi, J. & Sugimoto, Y., 2011 11 18, : : Biochemical and Biophysical Research Communications. 415, 2, p. 305-312 8 p.

研究成果: Article

5 引用 (Scopus)
2010

A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor

Yashiroda, Y., Okamoto, R., Hatsugai, K., Takemoto, Y., Goshima, N., Saito, T., Hamamoto, M., Sugimoto, Y., Osada, H., Seimiya, H. & Yoshida, M., 2010 4 9, : : Biochemical and Biophysical Research Communications. 394, 3, p. 569-573 5 p.

研究成果: Article

30 引用 (Scopus)

BCRP/ABCG2 confers anticancer drug resistance without covalent dimerization

Shigeta, J., Katayama, K., Mitsuhashi, J., Noguchi, K. & Sugimoto, Y., 2010 8 1, : : Cancer science. 101, 8, p. 1813-1821 9 p.

研究成果: Article

16 引用 (Scopus)

Breast cancer resistant protein (BCRP) is a molecular determinant of the outcome of photodynamic therapy (PDT) for centrally located early lung cancer

Usuda, J., Tsunoda, Y., Ichinose, S., Ishizumi, T., Ohtani, K., Maehara, S., Ono, S., Tsutsui, H., Ohira, T., Okunaka, T., Furukawa, K., Sugimoto, Y., Kato, H. & Ikeda, N., 2010 2 1, : : Lung Cancer. 67, 2, p. 198-204 7 p.

研究成果: Article

31 引用 (Scopus)

Functional availability of γ-herpesvirus K-cyclin is regulated by cellular CDK6 and p16INK4a

Yoshioka, H., Noguchi, K., Katayama, K., Mitsuhashi, J., Yamagoe, S., Fujimuro, M. & Sugimoto, Y., 2010 4 16, : : Biochemical and Biophysical Research Communications. 394, 4, p. 1000-1005 6 p.

研究成果: Article

3 引用 (Scopus)

In vivo expansion of MDR1-transduced cells accompanied by a post-transplantation chemotherapy regimen with mitomycin C and methotrexate

Mitsuhashi, J., Hosoyama, H., Tsukahara, S., Katayama, K., Noguchi, K., Ito, Y., Hatake, K., Aiba, K., Takahashi, S. & Sugimoto, Y., 2010 7 1, : : Journal of Gene Medicine. 12, 7, p. 596-603 8 p.

研究成果: Article

2 引用 (Scopus)

Pharmacological interaction with sunitinib is abolished by a germ-line mutation (1291T>C) of BCRP/ABCG2 gene

Kawahara, H., Noguchi, K., Katayama, K., Mitsuhashi, J. & Sugimoto, Y., 2010 6 1, : : Cancer science. 101, 6, p. 1493-1500 8 p.

研究成果: Article

24 引用 (Scopus)

Tankyrase-1 assembly to large protein complexes blocks its telomeric function

Hatsugai, K., Ohishi, T., Sugimoto, Y. & Seimiya, H., 2010 9, : : FEBS Letters. 584, 18, p. 3885-3890 6 p.

研究成果: Article

4 引用 (Scopus)
2009

Acyl-CoA synthetase as a cancer survival factor: Its inhibition enhances the efficacy of etoposide

Mashima, T., Sato, S., Okabe, S., Miyata, S., Matsuura, M., Sugimoto, Y., Tsuruo, T. & Seimiya, H., 2009 7 23, : : Cancer science. 100, 8, p. 1556-1562 7 p.

研究成果: Article

39 引用 (Scopus)

CMC-544 (inotuzumab ozogamicin), an anti-CD22 immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells

Takeshita, A., Yamakage, N., Shinjo, K., Ono, T., Hirano, I., Nakamura, S., Shigeno, K., Tobita, T., Maekawa, M., Kiyoi, H., Naoe, T., Ohnishi, K., Sugimoto, Y. & Ohno, R., 2009, : : Leukemia. 23, 7, p. 1329-1336 8 p.

研究成果: Article

17 引用 (Scopus)

CMC-544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: Analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma

Takeshita, A., Shinjo, K., Yamakage, N., Ono, T., Hirano, I., Matsui, H., Shigeno, K., Nakamura, S., Tobita, T., Maekawa, M., Ohnishi, K., Sugimoto, Y., Kiyoi, H., Naoe, T. & Ohno, R., 2009 7, : : British Journal of Haematology. 146, 1, p. 34-43 10 p.

研究成果: Article

39 引用 (Scopus)