Yoshikazu Sugimoto

1992

Determinants of response to the DNA topoisomerase II inhibitors doxorubicin and etoposide in human lung cancer cell lines

Kasahara, K., Fujiwara, Y., Sugimoto, Y., Nishio, K., Tamura, T., Matsuda, T. & Saijo, N., 1992 1月 15, In: Journal of the National Cancer Institute. 84, 2, p. 113-118 6 p.

研究成果: Article › 査読

89 被引用数 (Scopus)

Differential expression of DNA topoisomerase I gene between CPT-11 acquired-and native-resistant human pancreatic tumor cell lines: Detected by RNA PCR-based quantitation assay

Takeda, S., Shimazoe, T., Sato, K., Sugimoto, Y., Tsuruo, T. & Kono, A., 1992 4月 30, In: Biochemical and Biophysical Research Communications. 184, 2, p. 618-625 8 p.

研究成果: Article › 査読

35 被引用数 (Scopus)

Expression of a human multidrug resistance gene in human ovarian carcinoma cell lines

Sekiya, S., Nunoyama, T., Shirasawa, H., Kimura, H., Kawata, M., Iijima, N., Sugimoto, Y., Tsuruo, T. & Takamizawa, H., 1992 6月, In: Archives of gynecology and obstetrics. 251, 2, p. 79-86 8 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Increased phosphorylation of nuclear phosphoproteins in human lung‐cancer cells resistant to cis‐diamminedichloroplatinum(II)

Nishio, K., Sugimoto, Y., Kasahara, K., Fujiwara, Y., Nishiwaki, S., Fujiki, H., Ohata, M. & Saijo, N., 1992 2月 1, In: International Journal of Cancer. 50, 3, p. 438-442 5 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

In vitro enhancement of fluoropyrimidine-induced cytotoxicity by leucovorin in colorectal and gastric carcinoma cell lines but not in non-small-cell lung carcinoma cell lines

Sugimoto, Y., Ohe, Y., Nishio, K., Ohmori, T., Fujiwara, Y. & SAijo, N., 1992 11月, In: Cancer Chemotherapy and Pharmacology. 30, 6, p. 417-422 6 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Mechanisms of collateral sensitivity to fluorouracil of a cis-diamminedichloroplatinum(Ii)-resistant human non-small lung cancer cell line

Sugimoto, Y., Ohe, Y., Nishio, K., Ohmori, T., Morikage, T., Fujiwara, Y. & Saijo, N., 1992 6月, In: British Journal of Cancer. 65, 6, p. 857-864 8 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Phospholipase C-mediated hydrolysis of phosphatidylcholine is activated by cis-diamminedichloroplatinum(II)

Nishio, K., Sugimoto, Y., Fujiwara, Y., Ohmori, T., Morikage, T., Takeda, Y., Ohata, M. & Saijo, N., 1992, In: Journal of Clinical Investigation. 89, 5, p. 1622-1628 7 p.

研究成果: Article › 査読

Open Access

25 被引用数 (Scopus)

1991

Characterization of an Etoposide‐resistant Human K562 Cell Line, K/eto

Sugawara, I., Iwahashi, T., Okamoto, K., Sugimoto, Y., Ekimoto, H., Tsuruo, T., Ikeuchi, T. & Mori, S., 1991 9月, In: Japanese Journal of Cancer Research. 82, 9, p. 1035-1043 9 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Establishment of a human leukemia subline resistant to the growth‐inhibitory effect of 12‐o‐tetradecanoylphorbol 13‐acetate (TPA) and showing non‐P‐glycoprotein‐mediated multi‐drug resistance

Takeda, Y., Nishio, K., Sugimoto, Y., Kasahara, K., Kubo, S., Fujiwara, Y., Saijo, N. & Niitani, H., 1991 7月 30, In: International Journal of Cancer. 48, 6, p. 931-937 7 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Identification and Characterization of Three DNA‐binding Proteins on the Promoter of the Human MDRl Gene in Drug‐sensitive and ‐resistant Cells

Ogura, M., Takatori, T., Sugimoto, Y. & Tsuruo, T., 1991 10月, In: Japanese Journal of Cancer Research. 82, 10, p. 1151-1159 9 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Metallothionein Content Correlates with the Sensitivity of Human Small Cell Lung Cancer Cell Lines to Cisplatin

Kasahara, K., Fujiwara, Y., Nishio, K., Ohmori, T., Sugimoto, Y. & Saijo, N., 1991 6月, In: Cancer Research. 51, 12, p. 3237-3242 6 p.

研究成果: Article › 査読

250 被引用数 (Scopus)

Suppression of Experimental Lung Colonization of a Metastatic Variant of Murine Colon Adenocarcinoma 26 by a Monoclonal Antibody 8F11 Inhibiting Tumor Cell-induced Platelet Aggregation

Sugimoto, Y., Watanabe, M., Oh-hara, T., Sato, S. & Tsuruo, T., 1991 2月, In: Cancer Research. 51, 3, p. 921-925 5 p.

研究成果: Article › 査読

56 被引用数 (Scopus)

The development of a treatment model for lymph node metastasis in nude mice transplanted with rat fibrosarcoma clone A

Soejima, Y., Shen, W. M., Minato, K., Nishio, K., Sugimoto, Y., Fujiwara, Y., Tamura, T., Hara, K. & Saijo, N., 1991 1月 1, In: Invasion and Metastasis. 11, 3, p. 174-180 7 p.

研究成果: Article › 査読

1990

3′-Deamino-3′-morpholino-13-deoxo-10-hydroxycarminomycin Conquers Multidrug Resistance by Rapid Influx following Higher Frequency of Formation of DNA Single- and Double-Strand Breaks

Horichi, N., Tapiero, H., Sugimoto, Y., Bungo, M., Nishiyama, M., Fourcade, A., Lampidis, T. J., Kasahara, K., Sasaki, Y., Takahashi, T. & Saijo, N., 1990 8月 1, In: Cancer Research. 50, 15, p. 4698-4701 4 p.

研究成果: Article › 査読

36 被引用数 (Scopus)

Collateral sensitivity of cisplatin-resistant human lung cancer cell lines to thymidylate synthase inhibitors

Ohe, Y., Sugimoto, Y. & Saijo, N., 1990 12月 1, In: Cancer Journal. 3, 6, p. 332-336 5 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Cross-resistance to tumour promoters in human cancer cell lines resistant to adriamycin or cisplatin

Nishio, K., Sugimoto, Y., Nakagawa, K., Niimi, S., Fujiwara, Y., Bungo, M., Kasahara, K., Fujiki, H. & Saijo, N., 1990 9月, In: British Journal of Cancer. 62, 3, p. 415-419 5 p.

研究成果: Article › 査読

25 被引用数 (Scopus)

Decreased Expression of DNA Topoisomerase I in Camptothecin-resistant Tumor Cell Lines as Determined by a Monoclonal Antibody

Sugimoto, Y., Tsukahara, S., Oh-hara, T., Isoe, T. & Tsuruo, T., 1990 11月 1, In: Cancer Research. 50, 21, p. 6925-6930 6 p.

研究成果: Article › 査読

231 被引用数 (Scopus)

Detection of 300-kilodalton membrane protein in adriamycin-resistant human tumor cells by a monoclonal antibody MRK18

Sugimoto, Y., Okochi, E., Hamada, H., Oh-hara, T. & Tsuruo, T., 1990 6月 15, In: Biochemical and Biophysical Research Communications. 169, 2, p. 686-691 6 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Detection of Proteins that Recognize Platinum‐modified DNA Using Gel Mobility Shift Assay

Fujiwara, Y., Kasahara, K., Sugimoto, Y., Nishio, K., Ohmori, T. & Saijo, N., 1990 12月, In: Japanese Journal of Cancer Research. 81, 12, p. 1210-1213 4 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Determinants of Drug Response in a Cisplatin‐resistant Human Lung Cancer Cell Line

Fujiwara, Y., Sugimoto, Y., Kasahara, K., Bungo, M., Yamakido, M., Tew, K. D. & Saijo, N., 1990 5月, In: Japanese Journal of Cancer Research. 81, 5, p. 527-535 9 p.

研究成果: Article › 査読

Open Access

89 被引用数 (Scopus)

Elevated Expression of DNA Topoisomerase II in Camptothecin-resistant Human Tumor Cell Lines

Sugimoto, Y., Tsukahara, S., Oh-hara, T., Tsuruo, T. & Liu, L. F., 1990 12月 15, In: Cancer Research. 50, 24, p. 7962-7965 4 p.

研究成果: Article › 査読

133 被引用数 (Scopus)

Establishment of a camptothecin analogue (CPT-11)-resistant cell line of human non-small cell lung cancer: Characterization and mechanism of resistance

Kanzawa, F., Sugimoto, Y., Minato, K., Kasahara, K., Bungo, M., Nagakawa, K., Fujiwara, Y., Liu, L. F. & Saijo, N., 1990, In: Cancer Research. 50, 18, p. 5919-5924 6 p.

研究成果: Article › 査読

173 被引用数 (Scopus)

Establishment of highly metastatic variants of murine colon adenocarcinoma 26 under serum‐free conditions

Sugimoto, Y., Oh‐hara, T., Heike, Y., Watanabe, M., Nakatsuru, Y., Ishikawa, T. & Tsuruo, T., 1990 7月 15, In: International Journal of Cancer. 46, 1, p. 118-124 7 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Expression of a Mr 41,000 Glycoprotein Associated with Thrombin-independent Platelet Aggregation in High Metastatic Variants of Murine B16 Melanoma

Watanabe, M., Sugimoto, Y. & Tsuruo, T., 1990 10月 15, In: Cancer Research. 50, 20, p. 6657-6662 6 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

Inhibition of lung colonization of mouse colon 26 adenocarcinoma by recombinant mouse interferon β through a modification of platelet function

Tsuruo, T., Saito, H., Watanabe, M., Sugimoto, Y., Yamori, T. & Oh-Hara, T., 1990 3月 1, In: Clinical & Experimental Metastasis. 8, 2, p. 203-213 11 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Low metastatic potential of clone from murine colon adenocarcinoma 26 increased by transfection of activated c-erbb-2 gene

Yusa, K., Sugimoto, Y., Yamori, T., Yamamoto, T., Toyoshima, K. & Tsuruo, T., 1990 10月 17, In: Journal of the National Cancer Institute. 82, 20, p. 1633-1636 4 p.

研究成果: Article › 査読

35 被引用数 (Scopus)

Mechanism of action of a new macromolecular antitumor antibiotic, C-1027

Sugimoto, Y., Otani, T., Ole, S., Wierzba, K. & Yamada, Y., 1990, In: The Journal of Antibiotics. 43, 4, p. 417-421 5 p.

研究成果: Article › 査読

Open Access

89 被引用数 (Scopus)

Menogaril, an Anthracycline Compound with a Novel Mechanism of Action: Cellular Pharmacology

Wierzba, K., Sugimoto, Y., Matsuo, K. ., Toko, T., Takeda, S., Yamada, Y. & Tsukagoshi, S., 1990 8月, In: Japanese Journal of Cancer Research. 81, 8, p. 842-849 8 p.

研究成果: Article › 査読

Open Access

9 被引用数 (Scopus)

TAT-59, a new triphenylethylene derivative with antitumor activity against hormone-dependent tumors

Toko, T., Sugimoto, Y., Matsuo, K. I., Yamasaki, R., Takeda, S., Wierzba, K., Asao, T. & Yamada, Y., 1990 3月, In: European Journal of Cancer and Clinical Oncology. 26, 3, p. 397-404 8 p.

研究成果: Article › 査読

56 被引用数 (Scopus)

1989

A Fluorine-containing Anthracycline (ME2303) as a New Antitumor Agent against Murine and Human Tumors and Their Multidrug-resistant Sublines

Tsuruo, T., Yusa, K., Sudo, Y., Takamori, R. & Sugimoto, Y., 1989 10月 15, In: Cancer Research. 49, 20, p. 5537-5542 6 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

Expression of P‐Glycoprotein mRNA in Human Gastric Tumors

Sugimoto, Y., Asami, N. & Tsuruo, T., 1989 10月, In: Japanese Journal of Cancer Research. 80, 10, p. 993-999 7 p.

研究成果: Article › 査読

Open Access

15 被引用数 (Scopus)

Multidrug Resistance in Cultured Human Leukemia and Lymphoma Cell Lines Detected by a Monoclonal Antibody, MRK16

Ishida, Y., Ohtsu, T., Hamada, H., Sugimoto, Y., Tobinai, K., Minato, K., Tsuruo, T. & Shimoyama, M., 1989 10月, In: Japanese Journal of Cancer Research. 80, 10, p. 1006-1013 8 p.

研究成果: Article › 査読

Open Access

24 被引用数 (Scopus)

1988

Detection of drug resistance in human hematologic malignancy by monoclonal antibodies

Ohtsu, T., Shimoyama, M., Hamada, H., Sugimoto, Y., Ohkochi, E., Tsuruo, T., Ishida, Y., Tobinai, K. & Minato, K., 1988 1月 1, In: Acta Haematologica Japonica. 51, 8, p. 310-320 11 p.

研究成果: Article › 査読

Identification of a Platelet-aggregating Factor of Murine Colon Adenocarcinoma 26: M_r 44,000 Membrane Protein as Determined by Monoclonal Antibodies

Watanabe, M., Okochi, E., Sugimoto, Y. & Tsuruo, T., 1988 11月, In: Cancer Research. 48, 22, p. 6411-6416 6 p.

研究成果: Article › 査読

63 被引用数 (Scopus)

Mr 85,000 membrane protein specifically expressed in adriamycin-resistant human tumor cells

Hamada, H., Okochi, E., Watanabe, M., Oh-hara, T., Sugimoto, Y., Kawabata, H. & Tsuruo, T., 1988 12月 1, In: Cancer Research. 48, p. 7082-7087 6 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

1987

Acquisition of Metastatic Ability in Hybridomas between Two Low Metastatic Clones of Murine Colon Adenocarcinoma 26 Defective in Either Platelet-aggregating Activity or in Vivo Growth Potential

Sugimoto, Y., Oh-hara, T., Watanabe, M., Saito, H., Yamori, T. & Tsuruo, T., 1987 8月, In: Cancer Research. 47, 16, p. 4396-4401 6 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

Decreased expression of the amplified mdr1 gene in revertants of multidrug-resistant human myelogenous leukemia K562 occurs without loss of amplified DNA

Sugimoto, Y., Roninson, I. B. & Tsuruo, T., 1987, In: Molecular and cellular biology. 7, 12, p. 4549-4552 4 p.

研究成果: Article › 査読

36 被引用数 (Scopus)

Detection of Multidrug Resistance Markers, P-Glycoprotein and mdrl mRNA, in Human Leukemia Cells

Tsuruo, T., Sugimoto, Y., Hamada, H., Roninson, I., Okumura, M., Adachi, K., Morishima, Y. & Ohno, R., 1987, In: Japanese Journal of Cancer Research GANN. 78, 12, p. 1415-1419 5 p.

研究成果: Article › 査読

74 被引用数 (Scopus)

DNA-mediated Transfer and Cloning of a Human Multidrug-resistant Gene of Adriamycin-resistant Myelogenous Leukemia K562

Sugimoto, Y. & Tsuruo, T., 1987 5月 15, In: Cancer Research. 47, 10, p. 2620-2625 6 p.

研究成果: Article › 査読

62 被引用数 (Scopus)

1986

A² H NMR study on alteration of the membrane organization of mouse b16 melanoma cells treated with 12-O-tetradecanoylphorbol-13-acetate

Sugimoto, Y., Saito, H., Tabeta, R. & Kodama, M., 1986 10月, In: Journal of biochemistry. 100, 4, p. 867-874 8 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Transplantability and Sensitivity to Natural Killer Cells of Aclarubicin-resistant Murine Lymphoma

Sugimoto, Y., Hirakawa, Y., Tanaka, N., Tahara, M., Sato, I., Nishimura, T., Suzuki, H. & Tanaka, N., 1986 11月 1, In: Cancer Research. 46, 11, p. 5646-5648 3 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

1984

Binding of bile acids with rat colon and resultant perturbation of membrane organization as studied by uptake measurement and ³¹P nuclear magnetic resonance spectroscopy

Sugimoto, Y., Saito, H. & Tabeta, R., 1984, In: Gann, The Japanese Journal of Cancer Research. 75, 9, p. 798-808 11 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Isolation, drug sensitivity, and some biochemical and genetical properties of macromomycin-resistant mouse lymphoblastoma l5178y cells

Suzuki, H., Sugimoto, Y., Tanaka, K., Nishimura, T. & Tanaka, N., 1984 1月, In: Journal of Antibiotics. 37, 5, p. 602-609 8 p.

研究成果: Article › 査読

Open Access

4 被引用数 (Scopus)

1983

Alteration of plasma membrane of drug-resistant tumor cells: 230-Kilodalton protein identified by monoclonal antibody

Sugimoto, Y., Suzuki, H. & Tanaka, N., 1983 8月 12, In: Biochemical and Biophysical Research Communications. 114, 3, p. 969-975 7 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

Incorporation of bile acid of low concentration into model and biological membranes studied by H and ³¹P NMR¹

Saitô, H., Sugimoto, Y., Tabeta, R., Suzuki, S., Izumi, G., Kodama, M., Toyoshima, S. & Nagata, C., 1983 12月, In: Journal of biochemistry. 94, 6, p. 1877-1887 11 p.

研究成果: Article › 査読

29 被引用数 (Scopus)

1982

Mechanism of action of 2-crotonyloxymethyl-4,5,6-trihydroxycyclohex-2-enone, a sh inhibitory antitumor antibiotic, and its effect on drug-resistant neoplastic cells

Sugimoto, Y., Suzuki, H., Yamaki, H., Nishimura, T. & Tanaka, N., 1982, In: The Journal of Antibiotics. 35, 9, p. 1222-1230 9 p.

研究成果: Article › 査読

Open Access

32 被引用数 (Scopus)

1981

Alteration of membrane-associated enzymes in drug-resistant sublines of mouse lymphoblastoma L5178Y cells

Sugimoto, Y., Nishimura, T., Suzuki, H. & Tanaka, N., 1981, In: Journal of Antibiotics. 34, 9, p. 1200-1205 6 p.

研究成果: Article › 査読

Open Access

14 被引用数 (Scopus)

Evidence of altered influx of adriamycin into anthracycline-resistant cells

Sugimoto, Y., Nishimura, T., Suzuki, H. & Tanaka, N., 1981, In: Journal of Antibiotics. 34, 8, p. 1064-1066 3 p.

研究成果: Article › 査読

Open Access

27 被引用数 (Scopus)

Mechanism of inactivation of hepatitis B surface antigen by N(α)-cocoyl-L-arginine ethyl ester

Sugimoto, Y. & Toyoshima, S., 1981, In: Antimicrobial Agents and Chemotherapy. 20, 1, p. 120-127 8 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

1980

Influence of chemical modification of Nα-cocoyl-L-arginine ethyl ester on its hepatitis B surface antigen-inactivating effect

Sugimoto, Y. & Toyoshima, S., 1980, In: Antimicrobial Agents and Chemotherapy. 18, 4, p. 525-528 4 p.

研究成果: Article › 査読

杉本 芳一

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杉本芳一