年別の研究成果
年別の研究成果
- 43 件
検索結果
-
2022
A bis-pyridinium fullerene derivative induces apoptosis through the generation of ROS in BCR-ABL-positive leukemia cells
Sumi, K., Tago, K., Nakazawa, Y., Takahashi, K., Ohe, T., Mashino, T. & Funakoshi-Tago, M., 2022 2月 5, In: European journal of pharmacology. 916, 174714.研究成果: Article › 査読
1 被引用数 (Scopus) -
Combination of Lanosterol and Nilvadipine Nanosuspensions Rescues Lens Opacification in Selenite-Induced Cataractic Rats
Deguchi, S., Kadowaki, R., Otake, H., Taga, A., Nakazawa, Y., Misra, M., Yamamoto, N., Sasaki, H. & Nagai, N., 2022 7月, In: Pharmaceutics. 14, 7, 1520.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Novel Mechanism by a Bis-Pyridinium Fullerene Derivative to Induce Apoptosis by Enhancing the MEK-ERK Pathway in a Reactive Oxygen Species-Independent Manner in BCR-ABL-Positive Chronic Myeloid Leukemia-Derived K562 Cells
Sumi, K., Tago, K., Nakazawa, Y., Takahashi, K., Ohe, T., Mashino, T. & Funakoshi-Tago, M., 2022 1月 1, In: International journal of molecular sciences. 23, 2, 749.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Oral Formulation Based on Irbesartan Nanocrystals Improve Drug Solubility, Absorbability, and Efficacy
Nagai, N., Ogata, F., Ike, A., Shimomae, Y., Osako, H., Nakazawa, Y., Yamamoto, N. & Kawasaki, N., 2022 2月, In: Pharmaceutics. 14, 2, 387.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Role of mucoadhesive agent in ocular delivery of ganciclovir microemulsion: cytotoxicity evaluation in vitro and ex vivo
Choudhari, M., Nayak, K., Nagai, N., Nakazawa, Y., Khunt, D. & Misra, M., 2022, (Accepted/In press) In: International Ophthalmology.研究成果: Article › 査読
-
2021
Balance of drug residence and diffusion in lacrimal fluid determine ocular bioavailability in in situ gels incorporating tranilast nanoparticles
Minami, M., Otake, H., Nakazawa, Y., Okamoto, N., Yamamoto, N., Sasaki, H. & Nagai, N., 2021 9月, In: Pharmaceutics. 13, 9, 1425.研究成果: Article › 査読
Open Access4 被引用数 (Scopus) -
Capsaicin attenuates TGFβ2-induced epithelial-mesenchymal-transition in lens epithelial cells in vivo and in vitro
Sugiyama, Y., Nakazawa, Y., Sakagami, T., Kawata, S., Nagai, N., Yamamoto, N., Funakoshi-Tago, M. & Tamura, H., 2021 12月, In: Experimental Eye Research. 213, 108840.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
Differences in a single extracellular residue underlie adhesive functions of two zebrafish aqp0s
Vorontsova, I., Hall, J. E., Schilling, T. F., Nagai, N. & Nakazawa, Y., 2021 8月, In: Cells. 10, 8, 2005.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
Effect of alpha‐glucosyl‐hesperidin consumption on lens sclerosis and presbyopia
Nakazawa, Y., Doki, Y., Sugiyama, Y., Kobayashi, R., Nagai, N., Morisita, N., Endo, S., Funakoshi‐tago, M. & Tamura, H., 2021 2月, In: Cells. 10, 2, p. 1-11 11 p., 382.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Instillation of ophthalmic formulation containing nilvadipine nanocrystals attenuates lens opacification in shumiya cataract rats
Goto, R., Yamada, S., Otake, H., Nakazawa, Y., Oka, M., Yamamoto, N., Sasaki, H. & Nagai, N., 2021 12月, In: Pharmaceutics. 13, 12, 1999.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Oral consumption of α-glucosyl-hesperidin could prevent lens hardening, which causes presbyopia
Nakazawa, Y., Aoki, M., Doki, Y., Morishita, N., Endo, S., Nagai, N., Funakoshi-Tago, M. & Tamura, H., 2021 3月, In: Biochemistry and Biophysics Reports. 25, 100885.研究成果: Article › 査読
Open Access3 被引用数 (Scopus) -
Prevention of postprandial hyperglycemia by ophthalmic nanoparticles based on protamine zinc insulin in the rabbit
Deguchi, S., Ogata, F., Isaka, T., Otake, H., Nakazawa, Y., Kawasaki, N. & Nagai, N., 2021 3月, In: Pharmaceutics. 13, 3, 375.研究成果: Article › 査読
Open Access -
Regulation of the membrane trafficking of the mechanosensitive ion channels trpv1 and trpv4 by zonular tension, osmotic stress and activators in the mouse lens
Nakazawa, Y., Petrova, R. S., Sugiyama, Y., Nagai, N., Tamura, H. & Donaldson, P. J., 2021 12月 1, In: International journal of molecular sciences. 22, 23, 12658.研究成果: Article › 査読
Open Access6 被引用数 (Scopus) -
2020
Development of sustained-release ophthalmic formulation based on tranilast solid nanoparticles
Minami, M., Seiriki, R., Otake, H., Nakazawa, Y., Kanai, K., Tanino, T. & Nagai, N., 2020 4月 1, In: Materials. 13, 7, 1675.研究成果: Article › 査読
Open Access3 被引用数 (Scopus) -
Effect of a Lens Protein in Low-Temperature Culture of Novel Immortalized Human Lens Epithelial Cells (iHLEC-NY2)
Yamamoto, N., Takeda, S., Hatsusaka, N., Hiramatsu, N., Nagai, N., Deguchi, S., Nakazawa, Y., Takata, T., Kodera, S., Hirata, A., Kubo, E. & Sasaki, H., 2020 12月 11, In: Cells. 9, 12研究成果: Article › 査読
Open Access5 被引用数 (Scopus) -
In situ gelling systems using pluronic f127 enhance corneal permeability of indomethacin nanocrystals
Nagai, N., Isaka, T., Deguchi, S., Minami, M., Yamaguchi, M., Otake, H., Okamoto, N. & Nakazawa, Y., 2020 10月 1, In: International journal of molecular sciences. 21, 19, p. 1-14 14 p., 7083.研究成果: Article › 査読
Open Access11 被引用数 (Scopus) -
Novel sustained‐release drug delivery system for dry eye therapy by rebamipide nanoparticles
Nagai, N., Ishii, M., Seiriki, R., Ogata, F., Otake, H., Nakazawa, Y., Okamoto, N., Kanai, K. & Kawasaki, N., 2020 2月, In: Pharmaceutics. 12, 2, 155.研究成果: Article › 査読
Open Access10 被引用数 (Scopus) -
Oral intake of α-glucosyl-hesperidin ameliorates selenite-induced cataract formation
Nakazawa, Y., Aoki, M., Ishiwa, S., Morishita, N., Endo, S., Nagai, N., Yamamoto, N., Funakoshi-Tago, M. & Tamura, H., 2020, In: Molecular Medicine Reports. 21, 3, p. 1258-1266 9 p.研究成果: Article › 査読
Open Access9 被引用数 (Scopus) -
2019
Combination with l-menthol enhances transdermal penetration of indomethacin solid nanoparticles
Nagai, N., Ogata, F., Yamaguchi, M., Fukuoka, Y., Otake, H., Nakazawa, Y. & Kawasaki, N., 2019 8月 1, In: International journal of molecular sciences. 20, 15, 3644.研究成果: Article › 査読
Open Access13 被引用数 (Scopus) -
Energy-dependent endocytosis is responsible for drug transcorneal penetration following the instillation of ophthalmic formulations containing indomethacin nanoparticles
Nagai, N., Ogata, F., Otake, H., Nakazawa, Y. & Kawasaki, N., 2019, In: International journal of nanomedicine. 14, p. 1213-1227 15 p.研究成果: Article › 査読
Open Access40 被引用数 (Scopus) -
Verification and spatial mapping of TRPV1 and TRPV4 expression in the embryonic and adult mouse lens
Nakazawa, Y., Donaldson, P. J. & Petrova, R. S., 2019 9月, In: Experimental Eye Research. 186, 107707.研究成果: Article › 査読
20 被引用数 (Scopus) -
2018
Design of a transdermal formulation containing raloxifene nanoparticles for osteoporosis treatment
Nagai, N., Ogata, F., Otake, H., Nakazawa, Y. & Kawasaki, N., 2018, In: International journal of nanomedicine. 13, p. 5215-5229 15 p.研究成果: Article › 査読
Open Access29 被引用数 (Scopus) -
Effect of hesperetin derivatives on the development of selenite-induced cataracts in rats
Nakazawa, Y., Pauze, M., Fukuyama, K., Nagai, N., Funakoshi-Tago, M., Sugai, T. & Tamura, H., 2018 7月, In: Molecular Medicine Reports. 18, 1, p. 1043-1050 8 p.研究成果: Article › 査読
Open Access10 被引用数 (Scopus) -
Involvement of endocytosis in the transdermal penetration mechanism of ketoprofen nanoparticles
Nagai, N., Ogata, F., Ishii, M., Fukuoka, Y., Otake, H., Nakazawa, Y. & Kawasaki, N., 2018 7月 23, In: International journal of molecular sciences. 19, 7, 2138.研究成果: Article › 査読
Open Access23 被引用数 (Scopus) -
Roasted Coffee Reduces β-Amyloid Production by Increasing Proteasomal β-Secretase Degradation in Human Neuroblastoma SH-SY5Y Cells
Fukuyama, K., Kakio, S., Nakazawa, Y., Kobata, K., Funakoshi-Tago, M., Suzuki, T. & Tamura, H., 2018 11月, In: Molecular Nutrition and Food Research. 62, 21, 1800238.研究成果: Article › 査読
16 被引用数 (Scopus) -
2017
Administration of antioxidant compounds affects the lens chaperone activity and prevents the onset of cataracts
Nakazawa, Y., Nagai, N., Ishimori, N., Oguchi, J. & Tamura, H., 2017 11月, In: Biomedicine and Pharmacotherapy. 95, p. 137-143 7 p.研究成果: Article › 査読
11 被引用数 (Scopus) -
Alpha-tocopherol attenuates the anti-tumor activity of crizotinib against cells transformed by NPM-ALK
Uchihara, Y., Ueda, F., Tago, K., Nakazawa, Y., Ohe, T., Mashino, T., Yokota, S., Kasahara, T., Tamura, H. & Funakoshi-Tago, M., 2017 8月, In: PloS one. 12, 8, e0183003.研究成果: Article › 査読
11 被引用数 (Scopus) -
A nanoparticle-based ophthalmic formulation of dexamethasone enhances corneal permeability of the drug and prolongs its corneal residence time
Nagai, N., Nakazawa, Y., Ito, Y., Kanai, K., Okamoto, N. & Shimomura, Y., 2017, In: Biological and Pharmaceutical Bulletin. 40, 7, p. 1055-1062 8 p.研究成果: Article › 査読
Open Access11 被引用数 (Scopus) -
Co-instillation of nano-solid magnesium hydroxide enhances corneal permeability of dissolved timolol
Nagai, N., Ogata, F., Otake, H., Kawasaki, N., Nakazawa, Y., Kanai, K., Okamoto, N. & Shimomura, Y., 2017 12月, In: Experimental Eye Research. 165, p. 118-124 7 p.研究成果: Article › 査読
10 被引用数 (Scopus) -
Improvement of dissolution rate and stability in a pirenoxine ophthalmic suspension by the bead mill methods
Ueno, A., Yamaoka, S., Ito, Y., Kotake, T., Nakazawa, Y. & Nagai, N., 2017, In: Yakugaku Zasshi. 137, 5, p. 635-641 7 p.研究成果: Article › 査読
Open Access -
Model for studying anti- allergic drugs for allergic conjunctivitis in animals
Nakazawa, Y., Oka, M. & Takehana, M., 2017 1月 1, In: Open Medicine (Poland). 12, 1, p. 231-238 8 p.研究成果: Article › 査読
Open Access5 被引用数 (Scopus) -
Ophthalmic formulation containing nilvadipine nanoparticles prevents retinal dysfunction in rats injected with streptozotocin
Deguchi, S., Otake, H., Nakazawa, Y., Hiramatsu, N., Yamamoto, N. & Nagai, N., 2017 12月 15, In: International journal of molecular sciences. 18, 12, 2720.研究成果: Article › 査読
Open Access10 被引用数 (Scopus) -
Roasting Enhances the Anti-Cataract Effect of Coffee Beans: Ameliorating Selenite-Induced Cataracts in Rats
Ishimori, N., Oguchi, J., Nakazawa, Y., Kobata, K., Funakoshi-Tago, M. & Tamura, H., 2017 6月 3, In: Current Eye Research. 42, 6, p. 864-870 7 p.研究成果: Article › 査読
14 被引用数 (Scopus) -
The Extracellular C-loop Domain Plays an Important Role in the Cell Adhesion Function of Aquaporin 0
Nakazawa, Y., Oka, M., Funakoshi-Tago, M., Tamura, H. & Takehana, M., 2017 4月 3, In: Current Eye Research. 42, 4, p. 617-624 8 p.研究成果: Article › 査読
9 被引用数 (Scopus) -
2016
Effect of hesperetin on chaperone activity in selenite-induced cataract
Nakazawa, Y., Oka, M., Tamura, H. & Takehana, M., 2016 6月 1, In: Open Medicine (Poland). 11, 1, p. 183-189 7 p.研究成果: Article › 査読
12 被引用数 (Scopus) -
2015
Establishment of a recessive mutant small-eye rat with lens involution and retinal detachment associated with partial deletion and rearrangement of the Cryba1 gene
Yamada, T., Nanashima, N., Shimizu, T., Nakazawa, Y., Nakazawa, M. & Tsuchida, S., 2015 10月 15, In: Biochemical Journal. 471, 2, p. 293-305 13 p.研究成果: Article › 査読
-
Hesperetin prevents selenite-induced cataract in rats
Nakazawa, Y., Oka, M., Bando, M. & Takehana, M., 2015 7月 31, In: Molecular vision. 21, p. 804-810 7 p.研究成果: Article › 査読
20 被引用数 (Scopus) -
2011
Quantitative analysis of ascorbic acid permeability of aquaporin 0 in the lens
Nakazawa, Y., Oka, M., Mitsuishi, A., Bando, M. & Takehana, M., 2011 11月 11, In: Biochemical and Biophysical Research Communications. 415, 1, p. 125-130 6 p.研究成果: Article › 査読
8 被引用数 (Scopus) -
The effect of the interaction between aquaporin 0 (AQP0) and the filensin tail region on AQP0 water permeability
Nakazawa, Y., Oka, M., Furuki, K., Mitsuishi, A., Nakashima, E. & Takehana, M., 2011 12月 13, In: Molecular vision. 17, p. 3191-3199 9 p.研究成果: Article › 査読
17 被引用数 (Scopus) -
The role of ascorbic acid transporter in the lens of streptozotocin-induced diabetic rat
Nakazawa, Y., Oka, M., Bando, M., Inoue, T. & Takehana, M., 2011 1月, In: Biomedicine and Preventive Nutrition. 1, 1, p. 43-48 6 p.研究成果: Article › 査読
7 被引用数 (Scopus) -
2010
Characterization and localization of side population cells in the lens
Oka, M., Toyoda, C., Kaneko, Y., Nakazawa, Y., Aizu-Yokota, E. & Takehana, M., 2010, In: Molecular vision. 16, p. 945-953 9 p.研究成果: Article › 査読
24 被引用数 (Scopus) -
The role of ascorbic acid transporter in the lens of streptozotocin-induced diabetic rat
Nakazawa, Y., Oka, M., Bando, M., Inoue, T. & Takehana, M., 2010, In: Biomedicine and Pharmacotherapy.研究成果: Article › 査読
-
2007
Cooperative interaction between ETS1 and GFI1 transcription factors in the repression of Bax gene expression
Nakazawa, Y., Suzuki, M., Manabe, N., Yamada, T., Kihara-Negishi, F., Sakurai, T., Tenen, D. G., Iwama, A., Mochizuki, M. & Oikawa, T., 2007 5月 24, In: Oncogene. 26, 24, p. 3541-3550 10 p.研究成果: Article › 査読
30 被引用数 (Scopus)