TY - JOUR
T1 - 頸動脈小体腫瘍の診断と治療
AU - Ozawa, Hiroyuki
N1 - Publisher Copyright:
© 2022 Society of Practical Otolaryngology. All rights reserved.
PY - 2022
Y1 - 2022
N2 - With the widespread application of genetic testing in recent years, the pathogenesis of carotid body tumors has been clarified. At present, tumor resection is the only curative treatment, with the high risk of perioperative complications, such as intraoperative hemorrhage, inferior cerebral nerve dysfunction, and cerebral infarction. A multidisciplinary team approach is essential for planning safe surgical resection. In addition, treatment options are limited for cases with unresectable disease, such as those with invasion of adjacent structures and/or distant metastasis. New treatment methods are developing. In the near future, new therapies targeting factors contributing to tumor development, such as SDHx, and tumor progression are expected to be developed.
AB - With the widespread application of genetic testing in recent years, the pathogenesis of carotid body tumors has been clarified. At present, tumor resection is the only curative treatment, with the high risk of perioperative complications, such as intraoperative hemorrhage, inferior cerebral nerve dysfunction, and cerebral infarction. A multidisciplinary team approach is essential for planning safe surgical resection. In addition, treatment options are limited for cases with unresectable disease, such as those with invasion of adjacent structures and/or distant metastasis. New treatment methods are developing. In the near future, new therapies targeting factors contributing to tumor development, such as SDHx, and tumor progression are expected to be developed.
KW - carotid body tumor
KW - multidisciplinary team approach
KW - SDHB variant
KW - SDHD variant
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U2 - 10.5631/jibirin.115.259
DO - 10.5631/jibirin.115.259
M3 - Article
AN - SCOPUS:85137097398
VL - 115
SP - 259
EP - 264
JO - Practica Oto-Rhino-Laryngologica
JF - Practica Oto-Rhino-Laryngologica
SN - 0032-6313
IS - 4
ER -