In the present study, we used the typical false recognition paradigm to test a hypothesis that the ventromedial prefrontal cortex (VMPFC) mediates event-category judgement and retrieving past similar events. Eight VMPFC patients and 10 normal subjects were first requested to learn 18 sets of 14 semantic associates. In the test phase, participants were asked to recognize paired words including true words, related lures, and unrelated lures. The VMPFC patients showed significantly higher false alarm rates than the normal subjects for lure words. A further analysis suggests that the VMPFC patients succeeded in judging the event category, yet they were more likely to fail to retrieve past similar events.
|ジャーナル||Brain and Cognition|
|出版ステータス||Published - 2001 12 1|
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