A bisindole alkaloid with hedgehog signal inhibitory activity from the myxomycete perichaena chrysosperma

Akinori Shintani, Kazufumi Toume, Yusnita Rifai, Midori A. Arai, Masami Ishibashi

研究成果: Article査読

19 被引用数 (Scopus)

抄録

6-Hydroxy-9′-methoxystaurosporinone (1), a new bisindole alkaloid, was isolated from field-collected fruiting bodies of the myxomycete Perichaena chrysosperma, together with two known compounds. The structure of the new alkaloid was elucidated from spectral data, and compound 1 was shown to have hedgehog signal inhibitory activity. A related new alkaloid, 6,9′-dihydroxystaurosporinone (4), was also isolated from Arcyria cinerea.

本文言語English
ページ(範囲)1711-1713
ページ数3
ジャーナルJournal of Natural Products
73
10
DOI
出版ステータスPublished - 2010 10 22
外部発表はい

ASJC Scopus subject areas

  • 分析化学
  • 分子医療
  • 薬理学
  • 薬科学
  • 創薬
  • 補完代替医療
  • 有機化学

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