TY - JOUR
T1 - A bisindole alkaloid with hedgehog signal inhibitory activity from the myxomycete perichaena chrysosperma
AU - Shintani, Akinori
AU - Toume, Kazufumi
AU - Rifai, Yusnita
AU - Arai, Midori A.
AU - Ishibashi, Masami
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2010/10/22
Y1 - 2010/10/22
N2 - 6-Hydroxy-9′-methoxystaurosporinone (1), a new bisindole alkaloid, was isolated from field-collected fruiting bodies of the myxomycete Perichaena chrysosperma, together with two known compounds. The structure of the new alkaloid was elucidated from spectral data, and compound 1 was shown to have hedgehog signal inhibitory activity. A related new alkaloid, 6,9′-dihydroxystaurosporinone (4), was also isolated from Arcyria cinerea.
AB - 6-Hydroxy-9′-methoxystaurosporinone (1), a new bisindole alkaloid, was isolated from field-collected fruiting bodies of the myxomycete Perichaena chrysosperma, together with two known compounds. The structure of the new alkaloid was elucidated from spectral data, and compound 1 was shown to have hedgehog signal inhibitory activity. A related new alkaloid, 6,9′-dihydroxystaurosporinone (4), was also isolated from Arcyria cinerea.
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U2 - 10.1021/np1002687
DO - 10.1021/np1002687
M3 - Article
C2 - 20839811
AN - SCOPUS:77958530772
VL - 73
SP - 1711
EP - 1713
JO - Journal of Natural Products
JF - Journal of Natural Products
SN - 0163-3864
IS - 10
ER -