A case of atypical POEMS syndrome without polyneuropathy

Ryuji Morizane, Hiroyuki Sasamura, Hitoshi Minakuchi, Yujiro Takae, Haruhito Kikuchi, Naomi Yoshiya, Akinori Hashiguchi, Konosuke Konishi, Shinichiro Okamoto, Hiroshi Itoh

研究成果: Article

11 引用 (Scopus)

抄録

POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, M-protein, Skin changes) syndrome is a rare hematological disease associated with overproduction of pro-inflammatory cytokines. Under the current nomenclature and diagnostic criteria for POEMS syndrome, the presence of characteristic polyneuropathy is required for diagnosis. We report a 43-year-old Japanese woman with organomegaly, endocrinopathy, M-protein, skin lesions, as well as typical renal lesions and sclerotic bone lesions. Of note, neurological examinations and peripheral nerve conduction tests were normal in this patient. In view of the overwhelming number of otherwise characteristic signs and symptoms, we made a provisional diagnosis of 'atypical POEMS syndrome without polyneuropathy'. If further similar cases are reported in the future, reconsideration of the nomenclature and/or diagnostic criteria for POEMS syndrome may be required.

元の言語English
ページ(範囲)452-455
ページ数4
ジャーナルEuropean Journal of Haematology
80
発行部数5
DOI
出版物ステータスPublished - 2008 5

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POEMS Syndrome
Polyneuropathies
Terminology
Hematologic Diseases
Neural Conduction
Neurologic Examination
Rare Diseases
Peripheral Nerves
Signs and Symptoms
Cytokines
Kidney
Bone and Bones
Skin
Proteins

ASJC Scopus subject areas

  • Hematology

これを引用

A case of atypical POEMS syndrome without polyneuropathy. / Morizane, Ryuji; Sasamura, Hiroyuki; Minakuchi, Hitoshi; Takae, Yujiro; Kikuchi, Haruhito; Yoshiya, Naomi; Hashiguchi, Akinori; Konishi, Konosuke; Okamoto, Shinichiro; Itoh, Hiroshi.

:: European Journal of Haematology, 巻 80, 番号 5, 05.2008, p. 452-455.

研究成果: Article

Morizane, Ryuji ; Sasamura, Hiroyuki ; Minakuchi, Hitoshi ; Takae, Yujiro ; Kikuchi, Haruhito ; Yoshiya, Naomi ; Hashiguchi, Akinori ; Konishi, Konosuke ; Okamoto, Shinichiro ; Itoh, Hiroshi. / A case of atypical POEMS syndrome without polyneuropathy. :: European Journal of Haematology. 2008 ; 巻 80, 番号 5. pp. 452-455.
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AU - Kikuchi, Haruhito

AU - Yoshiya, Naomi

AU - Hashiguchi, Akinori

AU - Konishi, Konosuke

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