A Case of Cowden's Disease Without Typical Skin Eruptions

Toshifumi Hibi, Atsushi Hayashi, Hiromasa Takaishi, Nagamu Inoue, Yoshitaka Ueno, Yasuo Hosoda, Mamoru Watanabe, Hiromasa Ishii, Takashi Inoue, Makio Mukai

研究成果: Article査読

1 被引用数 (Scopus)

抄録

A 21-year-old man was admitted to our hospital hoping for the follow-up of gastric polyps. X-ray and endoscopic examinations revealed multiple polypoid lesions in the esophagus, and multiple polyps in the stomach and colon. Esophageal epithelial thickening was demonstrated in the esophageal polypoid lesions. Gastric and colonic hyperplastic polyps were confirmed histologically. Although typical skin findings were absent, Cowden's disease was strongly suggested by clinical features such as adenoid appearance, goiter, arteriovenous malformation and gingival papillomatosis. Cowden's disease is characterized by multiple hyperplastic or hamartomatous development originating from three embryonic germ layers in the whole body. Cowden's disease is frequently complicated with malignant tumors and should be considered in the differential diagnosis of various diseases with gastrointestinal polyposis.

本文言語English
ページ(範囲)65-71
ページ数7
ジャーナルGastroenterological Endoscopy
37
1
DOI
出版ステータスPublished - 1995
外部発表はい

ASJC Scopus subject areas

  • 放射線学、核医学およびイメージング
  • 消化器病学

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