A case of intrahepatic cholangiocarcinoma effectively treated by hepatic arterial infusion chemotherapy

Toshihiro Nishizawa, Hajime Higuchi, Hiromasa Takaishi, Hideko Iizuka, Motoko Izumiya, Yoshiyuki Yamagishi, Tadakazu Hisamatsu, Hidekazu Suzuki, Tatsuhiro Masaoka, Eisuke Iwasaki, Hiroshi Nagata, Toshifumi Hibi

研究成果: Article査読

抄録

The patient was a 50-year-old woman who suffered from gastric discomfort. She was first diagnosed as intrahepatic cholangiocarcinoma with hepatic, paraaortic lymphnodal and bone metastasis. Initial systemic chemotherapy using gemcitabine (GEM) and 5-FU failed to control the disease activity. Then she was given GEM and cisplatin (CDDP) combination chemotherapy. The response was assessed as stable disease (SD), but grade 4 leukopenia was seen. Then systemic therapy using GEM, and hepatic arterial infusion therapy with CDDP, l-leucovorin and 5-FU were continued biweekly. Partial response (PR) was achieved six months later, and her disease status was maintained as SD. This hepatic arterial infusion chemotherapy would be safe and feasible as therapy for inoperable intrahepatic cholangiocarcinoma.

本文言語English
ページ(範囲)1657-1659
ページ数3
ジャーナルGan to kagaku ryoho. Cancer & chemotherapy
33
11
出版ステータスPublished - 2006 11

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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