TY - JOUR
T1 - A case of Macular corneal dystrophy type II
AU - Shinoda, Hajime
AU - Nii, Seiji
AU - Yamada, Masakazu
AU - Nakamura, Yu
AU - Mashima, Yukihiko
AU - Takagishi, Kenji
PY - 1998/12/1
Y1 - 1998/12/1
N2 - Most cases of macular corneal dystrophy (MCD) can be classified as type 1, which is keratan sulfate (KS) negative, or type II (KS positive) by testing for the presence of KS in the cornea and in the serum. We examined a 55-year-old Japanese male who had MCD. Histochemical studies revealed that the patient's corneal stroma stained with anti-KS monoclonal antibody (5-D- 4). The KS level in the patient's serum, as determined by an enzyme-linked immunosorbent assay, was within the normal range. These results confirmed the diagnosis of MCD type II.
AB - Most cases of macular corneal dystrophy (MCD) can be classified as type 1, which is keratan sulfate (KS) negative, or type II (KS positive) by testing for the presence of KS in the cornea and in the serum. We examined a 55-year-old Japanese male who had MCD. Histochemical studies revealed that the patient's corneal stroma stained with anti-KS monoclonal antibody (5-D- 4). The KS level in the patient's serum, as determined by an enzyme-linked immunosorbent assay, was within the normal range. These results confirmed the diagnosis of MCD type II.
KW - Anti-Keratan Sulfate Monoclonal Antibody
KW - Corneal Keratan Sulfate
KW - Macular Corneal Dystrophy
KW - Serum Keratan Sulfate
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M3 - Article
AN - SCOPUS:0032425425
VL - 49
SP - 956
EP - 958
JO - Folia Ophthalmologica Japonica
JF - Folia Ophthalmologica Japonica
SN - 0015-5667
IS - 11
ER -