A case of primary gastric small cell carcinoma with a rare pattern of lymph node metastasis

Hiroya Takeuchi, Ken Futamata, Arafumi Maeshima, Shigemichi Hirose, Atsushi Shimada, Yoshiki Kawaguchi, Jo Tokuyama, Koji Osumi, Shinya Kishi, Takashi Hojo, Shiei Kim, Norihito Wada, Takashi Oishi, Yoh Isobe, Shunji Ikeuchi, Kiyoshi Kubochi, Sumio Matsumoto

研究成果: Article査読

3 被引用数 (Scopus)


We report a very rare case of primary gastric small cell carcinoma (GSCC) that was accompanied with gastric tubular adenocarcinoma. A male in his 60s had an elevated tumor with a central ulceration in the middle stomach. The patient underwent a distal gastrectomy with lymph node dissection. The pathological examination showed two separated lesions of the stomach, which contained the components of primary GSCC and primary gastric tubular adenocarcinoma. Immunohistochemical (IHC) examination demonstrated that the tumor cells in the small cell carcinoma stained positive for synaptophysin, chromogranin A, and neural cell adhesion molecule (NCAM). GSCC cells and adenocarcinoma cells independently metastasized to each regional lymph node. Further studies on the biological behavior of individual tumors may allow the development of new treatment strategies for GSCC.

ジャーナルInternational Journal of Gastrointestinal Cancer
出版ステータスPublished - 2005 10月

ASJC Scopus subject areas

  • 腫瘍学
  • 内分泌学
  • 消化器病学


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