A case of squamous cell carcinoma of the lung preceded by pulmonary aspergillosis

Nao Odajima, Koichi Yamazaki, Tomoko Betsuyaku, Masaharu Nishimura

研究成果: Article査読

抄録

Background. We report a case of squamous cell carcinoma of the lung preceded by pulmonary aspergillosis associated with interstitial pneumonia and diabetes mellitus. Case. An 81-year-old man had a consolidation in his left S9 detected by chest CT in March 2000, which was diagnosed as pulmonary aspergillosis. Despite antifungal therapy with itraconazole, rapid enlargement of the consolidation occured around November 2002. He was refered to our hospital for re-evaluation of the disease in March 2003. Squamous cell lung carcinoma was eventually detected by transbronchial biopsy and left lower lobectomy was performed. The pathological examination of the resected specimen showed aspergillus hyphae in the necrotic cavities of the squamous cell carcinoma, and interstitial pneumonia (nonspecific interstitial pneumonia: NSIP, group 2) was seen around the tumor. We speculate that saprophytic pulmonary aspergillosis occurred in the cysts formed by NSIP, and thereafter squamous cell carcinoma occured. Conclusion. When aspergillus infection is unresponsive to antimycotics, we should keep in mind that lung carcinoma may overlap fungal in-fection.

本文言語English
ページ(範囲)145-150
ページ数6
ジャーナルJapanese Journal of Lung Cancer
45
2
DOI
出版ステータスPublished - 2005 4月

ASJC Scopus subject areas

  • 腫瘍学
  • 呼吸器内科

フィンガープリント

「A case of squamous cell carcinoma of the lung preceded by pulmonary aspergillosis」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル