A case report: Severe bone marrow suppression caused by 6-mercaptopurin in Crohn's disease patient

Daisuke Kubota, Chizuru Takishima, Ken Ishii, Takahiro Kawamura, Tomoko Matsumoto, Yasuhiro Itsui, Eriko Okada, Seishin Chin, Shinya Oooka, Kiichiro Tsuchiya, Akihiro Araki, Naoya Sakamoto, Tatsuya Miyata, Takanori Kanai, Mamoru Watanabe

研究成果: Article査読

2 被引用数 (Scopus)

抄録

A 23-year-old man was admitted for treatment of acute exacerbation of ileitis and perianal abscess caused by Crohn's disease. After incision and drainage of the abscess, coupled with antibiotic therapy, 6-mercaptopurine (6-MP) was commenced. His white blood cell (WBC) count on day 12 after initiation of 6-MP was not decreased. However, on day 24 he was re-admitted because of severe myelosuppression (WBC: 300/μl), which was complicated by the recurrence of the perianal abscess. Myelosuppression was prolonged and required the administration of granulocyte colony stimulating factor (G-CSF). G-CSF was continued for 17 days to achieve recovery of his WBC count to a normal level.

本文言語English
ページ(範囲)1044-1049
ページ数6
ジャーナルJapanese Journal of Gastroenterology
103
9
出版ステータスPublished - 2006 9月 1
外部発表はい

ASJC Scopus subject areas

  • 消化器病学

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