A cross-sectional observation of effect of exposure to N-Methyl-2- Pyrrolidone (NMP) on workers' health

Shigeru Nishimura, Hirohiko Yasui, Hiroyuki Miyauchi, Yuriko Kikuchi, Nami Kondo, Toru Takebayashi, Shigeru Tanaka, Yuko Mikoshiba, Kazuyuki Omae, Tetsuo Nomiyama

研究成果: Article

4 引用 (Scopus)

抄録

This study was aimed at clarifying the effect of exposure to N-methyl-2-pyrrolidone (NMP) on workers' health. Fifteen male NMP-exposed workers and 15 referent male workers were recruited for this study. Exposure concentrations were assessed by determining NMP in the breathing zones and urinary NMP. Clinical examinations, motor and sensory nerve conduction velocities in the dominant arm, and neurobehavioral tests were carried out. The subjects were asked to complete self-administered questionnaires for subjective symptoms and psychological assessment. The mean NMP exposure concentrations ranged from 0.14 to 0.26 ppm, and urinary NMP levels at the end of each workday ranged from 0.17 to 0.22 mg/l, throughout the work week. In terms of clinical data, motor and sensory nerve conduction velocities, neurobehavioral tests, and subjective symptom assessments, there were no differences and no dose-dependent changes in either the means or the prevalence of abnormal findings between NMP-exposed and referent workers.

元の言語English
ページ(範囲)355-362
ページ数8
ジャーナルIndustrial Health
47
発行部数4
DOI
出版物ステータスPublished - 2009 7

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Observation
Health
Symptom Assessment
Neural Conduction
N-methylpyrrolidone
Respiration
Psychology

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

これを引用

A cross-sectional observation of effect of exposure to N-Methyl-2- Pyrrolidone (NMP) on workers' health. / Nishimura, Shigeru; Yasui, Hirohiko; Miyauchi, Hiroyuki; Kikuchi, Yuriko; Kondo, Nami; Takebayashi, Toru; Tanaka, Shigeru; Mikoshiba, Yuko; Omae, Kazuyuki; Nomiyama, Tetsuo.

:: Industrial Health, 巻 47, 番号 4, 07.2009, p. 355-362.

研究成果: Article

Nishimura, S, Yasui, H, Miyauchi, H, Kikuchi, Y, Kondo, N, Takebayashi, T, Tanaka, S, Mikoshiba, Y, Omae, K & Nomiyama, T 2009, 'A cross-sectional observation of effect of exposure to N-Methyl-2- Pyrrolidone (NMP) on workers' health', Industrial Health, 巻. 47, 番号 4, pp. 355-362. https://doi.org/10.2486/indhealth.47.355
Nishimura, Shigeru ; Yasui, Hirohiko ; Miyauchi, Hiroyuki ; Kikuchi, Yuriko ; Kondo, Nami ; Takebayashi, Toru ; Tanaka, Shigeru ; Mikoshiba, Yuko ; Omae, Kazuyuki ; Nomiyama, Tetsuo. / A cross-sectional observation of effect of exposure to N-Methyl-2- Pyrrolidone (NMP) on workers' health. :: Industrial Health. 2009 ; 巻 47, 番号 4. pp. 355-362.
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