A new, convenient cell-based screening method for small-molecule glycolytic inhibitors

Mitsuhiro Kitagawa, Mayuko Misawa, Seiichiro Ogawa, Etsu Tashiro, Masaya Imoto

研究成果: Article査読

5 被引用数 (Scopus)

抄録

To counteract active glycolysis in tumors, we developed a new, convenient cell-based screening system to identify an inhibitor of glycolysis. Using this system, we searched for an inhibitor in the synthetic Carbasugar library and found two candidates. It was found that both inhibited glycolysis by suppressing the glucose uptake step in tumor cells.

本文言語English
ページ(範囲)367-369
ページ数3
ジャーナルBioscience, Biotechnology and Biochemistry
75
2
DOI
出版ステータスPublished - 2011 3 7

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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