A new device for delivering drugs into the inner ear: Otoendoscope with microcatheter

Sho Kanzaki, Hideyuki Saito, Yasuhiro Inoue, Kaoru Ogawa

研究成果: Article査読

8 被引用数 (Scopus)

抄録

Objectives: Intratympanic injection (ITI) of drugs into the inner ear is an attractive way to deliver therapy. However, if the round window membrane (RWM) cannot be visualized, adhesions need to be removed first before ITI can be performed. We developed and tested a novel otoendoscopy device that allows visualization of the RWM for the purpose of ITI. Methods: Our otoendoscope consists of a catheter channel for delivering drugs and a suction channel. Results: The novel otoendoscope for inner ear drug delivery has a fine needle with catheter, which can be used to remove or perforate round window niche (RWN) mucosal adhesions. The elliptical shape of the otoendoscope effectively captures the field in the light-guided area, resulting in bright images. Conclusions: Our otoendoscope can be used to apply drugs directly onto the surface of the RWM and to verify the correct placement of an inner ear drug delivery system, ensuring that it is safely in place.

本文言語English
ページ(範囲)208-211
ページ数4
ジャーナルAuris Nasus Larynx
39
2
DOI
出版ステータスPublished - 2012 4月

ASJC Scopus subject areas

  • 外科
  • 耳鼻咽喉科学

フィンガープリント

「A new device for delivering drugs into the inner ear: Otoendoscope with microcatheter」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル