A new perspective on the mechanism of asymmetric amplification

Kouichi Asakura, Tetsuya Yamamoto, Sawako Inoue, Shuichi Osanai, Dilip K. Kondepudi, Tomohiko Yamaguchi

研究成果: Article

7 引用 (Scopus)

抄録

A mechanism of asymmetric amplification, i.e., chemical reaction in which enantiomeric excess, ee, of a product is higher than that of chiral auxiliary for catalyst, was investigated. The reaction rate and the ee of the product differed significantly when the order of reagent addition was changed. A kinetic model formulated to explain this phenomenon predicted that the ee of the product should vary during the reaction. Our experimental investigation indeed found the variation of ee predicted by this theoretical model. There has been no previous report observing such a variation in ee during asymmetric amplification and a different ee produced by changing the order of reagent addition.

元の言語English
ページ(範囲)312-317
ページ数6
ジャーナルChemical Physics Letters
406
発行部数4-6
DOI
出版物ステータスPublished - 2005 5 2

Fingerprint

Amplification
reagents
products
Reaction rates
Chemical reactions
Catalysts
Kinetics
chemical reactions
reaction kinetics
catalysts
kinetics

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Spectroscopy
  • Atomic and Molecular Physics, and Optics
  • Surfaces and Interfaces
  • Condensed Matter Physics

これを引用

Asakura, K., Yamamoto, T., Inoue, S., Osanai, S., Kondepudi, D. K., & Yamaguchi, T. (2005). A new perspective on the mechanism of asymmetric amplification. Chemical Physics Letters, 406(4-6), 312-317. https://doi.org/10.1016/j.cplett.2005.03.009

A new perspective on the mechanism of asymmetric amplification. / Asakura, Kouichi; Yamamoto, Tetsuya; Inoue, Sawako; Osanai, Shuichi; Kondepudi, Dilip K.; Yamaguchi, Tomohiko.

:: Chemical Physics Letters, 巻 406, 番号 4-6, 02.05.2005, p. 312-317.

研究成果: Article

Asakura, K, Yamamoto, T, Inoue, S, Osanai, S, Kondepudi, DK & Yamaguchi, T 2005, 'A new perspective on the mechanism of asymmetric amplification', Chemical Physics Letters, 巻. 406, 番号 4-6, pp. 312-317. https://doi.org/10.1016/j.cplett.2005.03.009
Asakura, Kouichi ; Yamamoto, Tetsuya ; Inoue, Sawako ; Osanai, Shuichi ; Kondepudi, Dilip K. ; Yamaguchi, Tomohiko. / A new perspective on the mechanism of asymmetric amplification. :: Chemical Physics Letters. 2005 ; 巻 406, 番号 4-6. pp. 312-317.
@article{728e1fa9abac4c37b1970daf3ae5eb62,
title = "A new perspective on the mechanism of asymmetric amplification",
abstract = "A mechanism of asymmetric amplification, i.e., chemical reaction in which enantiomeric excess, ee, of a product is higher than that of chiral auxiliary for catalyst, was investigated. The reaction rate and the ee of the product differed significantly when the order of reagent addition was changed. A kinetic model formulated to explain this phenomenon predicted that the ee of the product should vary during the reaction. Our experimental investigation indeed found the variation of ee predicted by this theoretical model. There has been no previous report observing such a variation in ee during asymmetric amplification and a different ee produced by changing the order of reagent addition.",
author = "Kouichi Asakura and Tetsuya Yamamoto and Sawako Inoue and Shuichi Osanai and Kondepudi, {Dilip K.} and Tomohiko Yamaguchi",
year = "2005",
month = "5",
day = "2",
doi = "10.1016/j.cplett.2005.03.009",
language = "English",
volume = "406",
pages = "312--317",
journal = "Chemical Physics Letters",
issn = "0009-2614",
publisher = "Elsevier",
number = "4-6",

}

TY - JOUR

T1 - A new perspective on the mechanism of asymmetric amplification

AU - Asakura, Kouichi

AU - Yamamoto, Tetsuya

AU - Inoue, Sawako

AU - Osanai, Shuichi

AU - Kondepudi, Dilip K.

AU - Yamaguchi, Tomohiko

PY - 2005/5/2

Y1 - 2005/5/2

N2 - A mechanism of asymmetric amplification, i.e., chemical reaction in which enantiomeric excess, ee, of a product is higher than that of chiral auxiliary for catalyst, was investigated. The reaction rate and the ee of the product differed significantly when the order of reagent addition was changed. A kinetic model formulated to explain this phenomenon predicted that the ee of the product should vary during the reaction. Our experimental investigation indeed found the variation of ee predicted by this theoretical model. There has been no previous report observing such a variation in ee during asymmetric amplification and a different ee produced by changing the order of reagent addition.

AB - A mechanism of asymmetric amplification, i.e., chemical reaction in which enantiomeric excess, ee, of a product is higher than that of chiral auxiliary for catalyst, was investigated. The reaction rate and the ee of the product differed significantly when the order of reagent addition was changed. A kinetic model formulated to explain this phenomenon predicted that the ee of the product should vary during the reaction. Our experimental investigation indeed found the variation of ee predicted by this theoretical model. There has been no previous report observing such a variation in ee during asymmetric amplification and a different ee produced by changing the order of reagent addition.

UR - http://www.scopus.com/inward/record.url?scp=16644385480&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=16644385480&partnerID=8YFLogxK

U2 - 10.1016/j.cplett.2005.03.009

DO - 10.1016/j.cplett.2005.03.009

M3 - Article

AN - SCOPUS:16644385480

VL - 406

SP - 312

EP - 317

JO - Chemical Physics Letters

JF - Chemical Physics Letters

SN - 0009-2614

IS - 4-6

ER -