TY - JOUR
T1 - A Phase III randomized trial of lobectomy versus limited resection for small-sized peripheral non-small cell lung cancer (JCOG0802/WJOG4607L)
AU - Nakamura, Kenichi
AU - Saji, Hisashi
AU - Nakajima, Ryu
AU - Okada, Morihito
AU - Asamura, Hisao
AU - Shibata, Taro
AU - Nakamura, Shinichiro
AU - Tada, Hirohito
AU - Tsuboi, Masahiro
N1 - Funding Information:
This work is supported in part by Grant-in-Aid for Cancer Research (20S-2, 20S-6) from the Ministry of Health, Labour and Welfare of Japan.
PY - 2009/11/22
Y1 - 2009/11/22
N2 - A Phase III study was started in Japan to evaluate the non-inferiority in overall survival of segmentectomy compared with lobectomy in patients with small-sized (diameter ≤2 cm) peripheral non-small cell lung cancer, excluding radiologically determined non-invasive cancer. This study began in August 2009, and a total of 1100 patients will be accrued from 71 institutions within 3 years. The primary endpoint is overall survival. The secondary endpoints are post-operative respiratory function, relapse-free survival, proportion of local recurrence, adverse events, proportion of patients who complete segmentectomy, duration of hospitalization, duration of chest tube placement, operation time, blood loss and number of autosutures used. This study is one of the first intergroup studies in Japan between the Japan Clinical Oncology Group and the West Japan Oncology Group.
AB - A Phase III study was started in Japan to evaluate the non-inferiority in overall survival of segmentectomy compared with lobectomy in patients with small-sized (diameter ≤2 cm) peripheral non-small cell lung cancer, excluding radiologically determined non-invasive cancer. This study began in August 2009, and a total of 1100 patients will be accrued from 71 institutions within 3 years. The primary endpoint is overall survival. The secondary endpoints are post-operative respiratory function, relapse-free survival, proportion of local recurrence, adverse events, proportion of patients who complete segmentectomy, duration of hospitalization, duration of chest tube placement, operation time, blood loss and number of autosutures used. This study is one of the first intergroup studies in Japan between the Japan Clinical Oncology Group and the West Japan Oncology Group.
KW - Clinical trial
KW - Non-small cell lung carcinoma
KW - Phase III
KW - Pneumonectomy
KW - Thoracic surgery
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U2 - 10.1093/jjco/hyp156
DO - 10.1093/jjco/hyp156
M3 - Article
C2 - 19933688
AN - SCOPUS:77950345964
VL - 40
SP - 271
EP - 274
JO - Japanese Journal of Clinical Oncology
JF - Japanese Journal of Clinical Oncology
SN - 0368-2811
IS - 3
M1 - hyp156
ER -