A physical map of the human genome

John D. McPherson, Marco Marra, La Deana Hillier, Robert H. Waterston, Asif Chinwalla, John Wallis, Mandeep Sekhon, Kristine Wylie, Elaine R. Mardis, Richard K. Wilson, Robert Fulton, Tamara A. Kucaba, Caryn Wagner-McPherson, William B. Barbazuk, Simon G. Gregory, Sean J. Humphray, Lisa French, Richard S. Evans, Graeme Bethel, Adam WhittakerJane L. Holden, Owen T. McCann, Andrew Dunham, Carol Soderlund, Carol E. Scott, David R. Bentley, Gregory Schuler, Hsiu Chuan Chen, Wonhee Jang, Eric D. Green, Jacquelyn R. Idol, Valerie V.Braden Maduro, Kate T. Montgomery, Eunice Lee, Ashley Miller, Suzanne Emerling, Raju Kucherlapati, Richard Gibbs, Steve Scherer, J. Harley Gorrell, Erica Sodergren, Kerstin Clerc-Blankenburg, Paul Tabor, Susan Naylor, Dawn Garcia, J. de Jong, Joseph J. Catanese, Norma Nowak, Kazutoyo Osoegawa, Shizhen Qin, Lee Rowen, Anuradha Madan, Monica Dors, Leroy Hood, Barbara Trask, Cynthia Friedman, Hillary Massa, Vivian G. Cheung, Ilan R. Kirsch, Thomas Reid, Raluca Yonescu, Jean Weissenbach, Thomas Bruls, Roland Heilig, Elbert Branscomb, Anne Olsen, Norman Doggett, Jan Fang Cheng, Trevor Hawkins, Richard M. Myers, Jin Shang, Lucia Ramirez, Jeremy Schmutz, Olivia Velasquez, Kami Dixon, Nancy E. Stone, David R. Cox, David Haussler, W. James Kent, Terrence Furey, Sanja Rogic, Scot Kennedy, Steven Jones, André Rosenthal, Gaiping Wen, Markus Schilhabel, Gernot Gloeckner, Gerald Nyakatura, Reiner Siebert, Brigitte Schlegelberger, Julie Korenberg, Xiao Ning Chen, Asao Fujiyama, Masahira Hattori, Atsushi Toyoda, Tetsushi Yada, Hong Seok Park, Yoshiyuki Sakaki, Nobuyoshi Shimizu, Shuichi Asakawa, Kazuhiko Kawasaki, Takashi Sasaki, Ai Shintani, Atsushi Shimizu, Kazunori Shibuya, Jun Kudoh, Shinsei Minoshima, Juliane Ramser, Peter Seranski, Celine Hoff, Annemarie Poustka, Richard Reinhardt, Hans Lehrach

研究成果: Article査読

698 被引用数 (Scopus)

抄録

The human genome is by far the largest genome to be sequenced, and its size and complexity present many challenges for sequence assembly. The International Human Genome Sequencing Consortium constructed a map of the whole genome to enable the selection of clones for sequencing and for the accurate assembly of the genome sequence. Here we report the construction of the whole-genome bacterial artificial chromosome (BAC) map and its integration with previous landmark maps and information from mapping efforts focused on specific chromosomal regions. We also describe the integration of sequence data with the map.

本文言語English
ページ(範囲)934-941
ページ数8
ジャーナルNature
409
6822
DOI
出版ステータスPublished - 2001 2 15

ASJC Scopus subject areas

  • 一般

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