@article{b8a01cf0b6e7479fbed4e1ac9d5c0c87,
title = "A practical approach for the chemical synthesis of 2′-deoxyguanosine-C8 adducts with mutagenic/carcinogenic amino- or nitro-arenes",
abstract = "Synthetic methods for the preparation of 2′-deoxyguanosine-C8 (dG-C8) adducts with several mutagenic and carcinogenic amino- or nitro-arenes were developed using the palladium-mediated cross-coupling reaction of protected 8-amino-dG with bromoarenes in around 80% yields, followed by conventional deprotection procedures. This approach can be applied to preparation of a variety of authentic dG-C8 adducts with amino or nitro-arenes.",
keywords = "Arylamination reaction, DG-C8 adducts",
author = "Takeji Takamura-Enya and Satoko Ishikawa and Masataka Mochizuki and Keiji Wakabayashi",
note = "Funding Information: This study was supported by a Grant-in-Aid for Cancer Research from the Ministry of Health, Labour and Welfare, Japan. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",
year = "2003",
month = aug,
day = "4",
doi = "10.1016/S0040-4039(03)01484-9",
language = "English",
volume = "44",
pages = "5969--5973",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "32",
}