A practical chemoenzymatic synthesis of a key intermediate of antifungal agents

Yoshihiko Yasohara; Kenji Miyamoto; Noriyuku Kizaki; Junzo Hasegawa; Takehisa Ohashi

doi:10.1016/S0040-4039(01)00425-7

A practical chemoenzymatic synthesis of a key intermediate of antifungal agents

Yoshihiko Yasohara, Kenji Miyamoto, Noriyuku Kizaki, Junzo Hasegawa, Takehisa Ohashi

研究成果: Article › 査読

21 被引用数 (Scopus)

抄録

A novel synthesis of an azole antifungal building block, the optically active diol, is described. The key step involves an enantioselective hydrolysis of a prochiral diester by a lipase.

本文言語	English
ページ（範囲）	3331-3333
ページ数	3
ジャーナル	Tetrahedron Letters
巻	42
号	19
DOI	https://doi.org/10.1016/S0040-4039(01)00425-7
出版ステータス	Published - 2001 5月 7
外部発表	はい

ASJC Scopus subject areas

生化学
創薬
有機化学

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10.1016/S0040-4039(01)00425-7

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AU - Ohashi, Takehisa

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A practical chemoenzymatic synthesis of a key intermediate of antifungal agents

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