A ratiometric fluorescent pH glass optode based on a boron-dipyrromethene derivative

Yosuke Ando, Shinji Iino, Koji Yamada, Keitaro Umezawa, Naoko Iwasawa, Daniel Citterio, Koji Suzuki

研究成果: Article査読

21 被引用数 (Scopus)

抄録

This paper describes the preparation of a single-excitation, dual-emission type optical pH-sensing device using a newly designed proton-responsive boron-dipyrromethene derivative (KBH-01). The indicator dye was successfully synthesized and immobilized covalently on the surface of a porous glass support (Corning 7930, 13 mm × 30 mm size with a thickness of 1 mm) having a large internal surface area (250 m2/g) using a silane-coupling agent. The resulting pH glass optode shows dual fluorescence emission in aqueous buffer solutions of varying pH values, allowing ratiometric signal processing. The response curves are independent of buffer ionic strength. The sensor response was found to be reversible in the pH range from below 0.8 to 4.5 and showed good repeatability. The determination of pH of gastric juice samples was demonstrated as a possible practical application of the pH glass optode. The pH values determined by the pH glass optode corresponded reasonably to those measured by a field effect transistor (FET) pH meter. These results indicate that the novel pH glass optode can be employed as a pH-sensing device with high durability, sensitivity and accuracy for medical and environmental analyses.

本文言語English
ページ(範囲)74-82
ページ数9
ジャーナルSensors and Actuators, B: Chemical
121
1
DOI
出版ステータスPublished - 2007 1月 30

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 器械工学
  • 凝縮系物理学
  • 表面、皮膜および薄膜
  • 金属および合金
  • 電子工学および電気工学
  • 材料化学

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